نتائج البحث - "Holthuis, Joost"

1

Academic Journal

Optical control of sphingolipid biosynthesis using photoswitchable sphingosines

المؤلفون: Kol, Matthijs, Novak, Alexander J.E., Morstein, Johannes, Schröer, Christian, Sokoya, Tolulope, Mensing, Svenja, Korneev, Sergei M., Trauner, Dirk, Holthuis, Joost C.M.

المساهمون: NIH NIGMS, German Research Foundation

المصدر: Journal of Lipid Research ; volume 66, issue 1, page 100724 ; ISSN 0022-2275

الاتاحة: https://doi.org/10.1016/j.jlr.2024.100724
https://api.elsevier.com/content/article/PII:S0022227524002293?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0022227524002293?httpAccept=text/plain

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2

Academic Journal

Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

المؤلفون: Sokoya, Tolulope, Parolek, Jan, Foged, Mads Moller, Danylchuk, Dmytro, Bozan, Manuel, Sarkar, Bingshati, Hilderink, Angelika, Philippi, Michael, Botto, Lorenzo D., Terhal, Paulien A., Makitie, Outi, Piehler, Jacob, Kim, Yeongho, Burd, Christopher G., Klymchenko, Andrey S., Maeda, Kenji, Holthuis, Joost C. M.

المساهمون: Clinicum, Children's Hospital, Lastentautien yksikkö, HUS Children and Adolescents

مصطلحات موضوعية: Human, Lipid order probes, Organellar lipidomics, Osteoporosis, Sphingomyelin biosensor, Transbilayer lipid asymmetry, Biomedicine

وصف الملف: application/pdf

Relation: Sokoya , T , Parolek , J , Foged , M M , Danylchuk , D , Bozan , M , Sarkar , B , Hilderink , A , Philippi , M , Botto , L D , Terhal , P A , Makitie , O , Piehler , J , Kim , Y , Burd , C G , Klymchenko , A S , Maeda , K & Holthuis , J C M 2022 , ' Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway ' , eLife , vol. 11 , e79278 . https://doi.org/10.7554/eLife.79278; ORCID: /0000-0002-4547-001X/work/155651714; http://hdl.handle.net/10138/354276; 22390f35-8b97-4115-8a7a-bab18e55bfa6; 000864031300001

الاتاحة: http://hdl.handle.net/10138/354276

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3

Academic Journal

Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase

المؤلفون: Jahn Helene, Bartoš Ladislav, Dearden Grace I., Dittman Jeremy S., Holthuis Joost C. M, Vácha Robert, Menon Anant K.

المصدر: Nature Communications

مصطلحات موضوعية: Mitochondria, Phospholipids, Saccharomyces cerevisiae, Voltage-Dependent Anion Channels

Relation: https://is.muni.cz/publication/2361877

الاتاحة: https://is.muni.cz/publication/2361877
https://doi.org/10.1038/s41467-023-43570-y

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4

Academic Journal

Membrane damage and repair: a thin line between life and death

المؤلفون: Barisch, Caroline, Holthuis, Joost C. M., Cosentino, Katia

المساهمون: Deutsche Forschungsgemeinschaft

المصدر: Biological Chemistry ; volume 404, issue 5, page 467-490 ; ISSN 1431-6730 1437-4315

الاتاحة: http://dx.doi.org/10.1515/hsz-2022-0321
https://www.degruyter.com/document/doi/10.1515/hsz-2022-0321/xml
https://www.degruyter.com/document/doi/10.1515/hsz-2022-0321/pdf

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5

Academic Journal

Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co-Condensation of Wnt Signalodroplets

المؤلفون: Philippi, Michael, Richter, Christian P, Kappen, Marie, Watrinet, Isabelle, Miao, Yi, Runge, Mercedes, Jorde, Lara, Korneev, Sergej, Holtmannspötter, Michael, Kurre, Rainer, Holthuis, Joost C M, Garcia, K Christopher, Plückthun, Andreas, Steinhart, Martin, Piehler, Jacob, You, Changjiang

المصدر: Philippi, Michael; Richter, Christian P; Kappen, Marie; Watrinet, Isabelle; Miao, Yi; Runge, Mercedes; Jorde, Lara; Korneev, Sergej; Holtmannspötter, Michael; Kurre, Rainer; Holthuis, Joost C M; Garcia, K Christopher; Plückthun, Andreas; Steinhart, Martin; Piehler, Jacob; You, Changjiang (2022). Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co-Condensation of Wnt Signalodroplets. Small, 18(50):2203723.

مصطلحات موضوعية: Department of Biochemistry, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/223624/8/Small___2022___Philippi___Biofunctional_Nanodot_Arrays_in_Living_Cells_Uncover_Synergistic_Co_Condensation_of_Wnt.pdf; info:pmid/36266931; urn:issn:1613-6810

الاتاحة: https://www.zora.uzh.ch/id/eprint/223624/
https://www.zora.uzh.ch/id/eprint/223624/8/Small___2022___Philippi___Biofunctional_Nanodot_Arrays_in_Living_Cells_Uncover_Synergistic_Co_Condensation_of_Wnt.pdf
https://doi.org/10.1002/smll.202203723

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6

Academic Journal

Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair

المؤلفون: Niekamp, Patrick, Felix, Scharte, Tolulope, Sokoya, Vittadello, Laura, Kim, Yeongho, Deng, Yongqiang, Südhoff, Elisabeth, Hilderink, Angelika, Imlau, Mirco, Clarke, Christopher J., Hensel, Michael, Burd, Christopher G., Holthuis, Joost C. M.

مصطلحات موضوعية: Calcium signalling, Lysosomes, Sphingolipids, ddc:570

وصف الملف: application/pdf

Relation: https://doi.org/10.1038/s41467-022-29481-4; https://doi.org/10.48693/302; Niekamp, P., Scharte, F., Sokoya, T., Vittadello, L., Kim, Y., Deng, Y., . . . Holthuis, J. C. M. (2022): Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair. Nature Communications, 13(1), 1875.; https://osnadocs.ub.uni-osnabrueck.de/bitstream/ds-202305028771/1/Niekamp_etal_naturecom_2022.pdf

الاتاحة: https://doi.org/10.48693/302
https://doi.org/10.1038/s41467-022-29481-4
https://osnadocs.ub.uni-osnabrueck.de/bitstream/ds-202305028771/1/Niekamp_etal_naturecom_2022.pdf

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7

Academic Journal

Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants

المؤلفون: Kunduri, Govind, Turner-Evans, Daniel, Konya, Yutaka, Izumi, Yoshihiro, Nagashima, Kunio, Lockett, Stephen, Holthuis, Joost, Bamba, Takeshi, Acharya, Usha, Acharya, Jairaj K.

المساهمون: Department of Molecular, Cell and Cancer Biology

المصدر: Proceedings of the National Academy of Sciences of the United States of America ; 115 ; 38 ; E8919-E8928

مصطلحات موضوعية: Drosophila, glia, neuron, photosensitive epilepsy, sphingolipids, Genetic Phenomena, Nervous System, Nervous System Diseases, Neuroscience and Neurobiology

Relation: Link to Article in PubMed; Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8919-E8928. doi:10.1073/pnas.1808463115. Epub 2018 Sep 5. Link to article on publisher's site; 0027-8424 (Linking); http://hdl.handle.net/20.500.14038/40800; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4620&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3608; oapubs/3608

الاتاحة: https://doi.org/10.1073/pnas.1808463115
https://hdl.handle.net/20.500.14038/40800
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4620&context=oapubs&unstamped=1
https://escholarship.umassmed.edu/oapubs/3608

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8

Academic Journal

Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

المؤلفون: Sokoya, Tolulope, Parolek, Jan, Foged, Mads Møller, Danylchuk, Dmytro I, Bozan, Manuel, Sarkar, Bingshati, Hilderink, Angelika, Philippi, Michael, Botto, Lorenzo D, Terhal, Paulien A, Mäkitie, Outi, Piehler, Jacob, Kim, Yeongho, Burd, Christopher G, Klymchenko, Andrey S, Maeda, Kenji, Holthuis, Joost CM

المساهمون: Deutsche Forschungsgemeinschaft, National Institutes of Health, Novo Nordisk Foundation, Independent Research Fund Denmark

المصدر: eLife ; volume 11 ; ISSN 2050-084X

الاتاحة: http://dx.doi.org/10.7554/elife.79278
https://cdn.elifesciences.org/articles/79278/elife-79278-v2.pdf
https://cdn.elifesciences.org/articles/79278/elife-79278-v2.xml
https://elifesciences.org/articles/79278

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9

Academic Journal

An alliance between lipid transfer proteins and scramblases for membrane expansion

المؤلفون: Holthuis, Joost C M, Jahn, Helene, Menon, Anant K, Mizushima, Noboru

المصدر: Faculty Reviews ; volume 11 ; ISSN 2732-432X

الاتاحة: http://dx.doi.org/10.12703/r-01-0000015

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10

Academic Journal

Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants

المؤلفون: Kunduri, Govind, Turner-Evans, Daniel, Konya, Yutaka, Izumi, Yoshihiro, Nagashima, Kunio, Lockett, Stephen, Holthuis, Joost, Bamba, Takeshi, Acharya, Usha, Acharya, Jairaj K.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2018 Sep . 115(38), E8919-E8928.

URL الوصول: https://www.jstor.org/stable/26531177

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11

Academic Journal

Short Photoswitchable Ceramides Enable Optical Control of Apoptosis

المؤلفون: Morstein, Johannes, Kol, Matthijs, Novak, Alexander J. E., Feng, Suihan, Khayyo, Shadi, Hinnah, Konstantin, Li-Purcell, Nasi, Pan, Grace, Williams, Benjamin M., Riezman, Howard, Atilla-Gokcumen, G. Ekin, Holthuis, Joost C. M., Trauner, Dirk

المصدر: ACS Chemical Biology, 16(3), 452-456, (2021-03-19)

مصطلحات موضوعية: Apoptosis, Bioactivity, Cell uptake, Lipids, Molecular structure

Relation: https://doi.org/10.1021/acschembio.0c00823

الاتاحة: https://doi.org/10.1021/acschembio.0c00823

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12

Academic Journal

Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry

المؤلفون: Niekamp, Patrick, Guzman, Gaelen, Leier, Hans C., Rashidfarrokhi, Ali, Richina, Veronica, Pott, Fabian, Barisch, Caroline, Holthuis, Joost C. M., Tafesse, Fikadu G.

المساهمون: Stallings, Christina L., Deutsche Forschungsgemeinschaft, Division of Intramural Research, National Institute of Allergy and Infectious Diseases

المصدر: mBio ; volume 12, issue 1 ; ISSN 2161-2129 2150-7511

الاتاحة: http://dx.doi.org/10.1128/mbio.03141-20
https://journals.asm.org/doi/pdf/10.1128/mBio.03141-20

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13

Academic Journal

A switchable ceramide transfer protein for dissecting the mechanism of ceramide‐induced mitochondrial apoptosis

المؤلفون: Jain, Amrita, Dadsena, Shashank, Holthuis, Joost C. M.

المساهمون: FP7 People: Marie-Curie Actions, Deutsche Forschungsgemeinschaft

المصدر: FEBS Letters ; volume 594, issue 22, page 3739-3750 ; ISSN 0014-5793 1873-3468

الاتاحة: http://dx.doi.org/10.1002/1873-3468.13956
https://onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.13956
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/1873-3468.13956
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1002/1873-3468.13956

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14

Academic Journal

Osteoporosis and skeletal dysplasia caused by pathogenic variants in SGMS2

المساهمون: Genetica Klinische Genetica, Child Health, Genetica Sectie Genoomdiagnostiek, Genetica Sectie Metabole Diagnostiek

مصطلحات موضوعية: General Medicine, Journal Article

وصف الملف: image/pdf

Relation: https://dspace.library.uu.nl/handle/1874/392199

الاتاحة: https://dspace.library.uu.nl/handle/1874/392199

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15

Academic Journal

Ceramides bind VDAC2 to trigger mitochondrial apoptosis

المؤلفون: Dadsena, Shashank, Bockelmann, Svenja, Mina, John G M, Hassan, Dina G, Korneev, Sergei, Razzera, Guilherme, Jahn, Helene, Niekamp, Patrick, Müller, Dagmar, Schneider, Markus, Tafesse, Fikadu G, Marrink, Siewert J, Melo, Manuel N, Holthuis, Joost C M

المصدر: Dadsena , S , Bockelmann , S , Mina , J G M , Hassan , D G , Korneev , S , Razzera , G , Jahn , H , Niekamp , P , Müller , D , Schneider , M , Tafesse , F G , Marrink , S J , Melo , M N & Holthuis , J C M 2019 , ' Ceramides bind VDAC2 to trigger mitochondrial apoptosis ' , Nature Communications , vol. 10 , no. 1 , 1832 . https://doi.org/10.1038/s41467-019-09654-4

مصطلحات موضوعية: Ceramides, apoptosis, mitochondria, Coarse-grain molecular dynamics simulations, VDAC2, RADIATION-INDUCED APOPTOSIS, DEPENDENT ANION CHANNEL-1, SPHINGOLIPID METABOLISM, CELL-DEATH, BAX, MEMBRANE, PROTEINS, INHIBITION, TRANSPORT, EFFICIENT