المؤلفون: Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah, Gilkes, Amanda F., Knapper, Steven, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L., Tonks, Alex

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/126243/1/TONKS,%20A%20-%20Integrated%20nuclear%20proteomics%20and%20transcriptomics.pdf; Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata https://orca.cardiff.ac.uk/view/cardiffauthors/A2302815N.html, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle https://orca.cardiff.ac.uk/view/cardiffauthors/A1816822.html, Baker, Sarah https://orca.cardiff.ac.uk/view/cardiffauthors/A393772C.html orcid:0000-0002-7474-9757 orcid:0000-0002-7474-9757, Gilkes, Amanda F. https://orca.cardiff.ac.uk/view/cardiffauthors/A062527N.html, Knapper, Steven https://orca.cardiff.ac.uk/view/cardiffauthors/A016111L.html orcid:0000-0002-6405-4441 orcid:0000-0002-6405-4441, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L. https://orca.cardiff.ac.uk/view/cardiffauthors/A008360O.html orcid:0000-0003-0879-0724 orcid:0000-0003-0879-0724 and Tonks, Alex https://orca.cardiff.ac.uk/view/cardiffauthors/A016105H.html orcid:0000-0002-6073-4976 orcid:0000-0002-6073-4976 2020. Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia. Leukemia 34 (2) , pp. 427-440. 10.1038/s41375-019-0596-4 https://doi.org/10.1038/s41375-019-0596-4 file https://orca.cardiff.ac.uk/id/eprint/126243/1/TONKS,%20A%20-%20Integrated%20nuclear%20proteomics%20and%20transcriptomics.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/126243/
https://doi.org/10.1038/s41375-019-0596-4

المؤلفون: Jones, Nicholas, Vincent, Emma E, Felix, Lindsey C, Cronin, James G, Scott, Louis M, Hole, Paul S, Lacy, Paige, Thornton, Catherine A

المصدر: Jones , N , Vincent , E E , Felix , L C , Cronin , J G , Scott , L M , Hole , P S , Lacy , P & Thornton , C A 2019 , ' Interleukin-5 drives glycolysis and reactive oxygen species-dependent citric acid cycling by eosinophils ' , Allergy . https://doi.org/10.1111/all.14158

مصطلحات موضوعية: /dk/atira/pure/core/keywords/icep, name=ICEP

وصف الملف: application/pdf

Relation: https://research-information.bris.ac.uk/en/publications/34b982a3-d64c-4362-93c1-df4a8cb70cf5

الاتاحة: https://hdl.handle.net/1983/34b982a3-d64c-4362-93c1-df4a8cb70cf5
https://research-information.bris.ac.uk/en/publications/34b982a3-d64c-4362-93c1-df4a8cb70cf5
https://doi.org/10.1111/all.14158
https://research-information.bris.ac.uk/ws/files/220514251/Metabolic_reprogramming_in_human_eosinophils_Interleukin_5_drives_glycolysis_and_ROS_dependent_TCA_cycling_UNMARKED.pdf

المؤلفون: Wadley, Alex J., Morgan, Rhys G., Heesom, Kate J., Hole, Paul S., Coles, Steven J.

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/120094/1/HOLE,%20Paul%20-%20Detecting%20intracellular%20thiol%20redox%20state%20in%20leukaemia%20and%20heterogeneous%20immune%20cell%20populations%20An%20optimised%20protocol%20for%20digital%20flow%20cytometers.pdf; Wadley, Alex J., Morgan, Rhys G., Heesom, Kate J., Hole, Paul S. and Coles, Steven J. 2018. Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers. MethodsX 5 , pp. 1473-1483. 10.1016/j.mex.2018.10.013 https://doi.org/10.1016/j.mex.2018.10.013 file https://orca.cardiff.ac.uk/id/eprint/120094/1/HOLE,%20Paul%20-%20Detecting%20intracellular%20thiol%20redox%20state%20in%20leukaemia%20and%20heterogeneous%20immune%20cell%20populations%20An%20optimised%20protocol%20for%20digital%20flow%20cytometers.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/120094/
https://doi.org/10.1016/j.mex.2018.10.013
https://orca.cardiff.ac.uk/id/eprint/120094/1/HOLE,%20Paul%20-%20Detecting%20intracellular%20thiol%20redox%20state%20in%20leukaemia%20and%20heterogeneous%20immune%20cell%20populations%20An%20optimised%20protocol%20for%20digital%20flow%20cytometers.pdf

المؤلفون: Khan, Naeem, Hills, Robert K., Knapper, Steve, Steadman, Lora, Qureshi, Ushna, Rector, Jerrald L., Bradbury, Charlotte, Russell, Nigel H., Vyas, Paresh, Burnett, Alan K., Grimwade, David, Hole, Paul S., Freeman, Sylvie D

المصدر: Khan , N , Hills , R K , Knapper , S , Steadman , L , Qureshi , U , Rector , J L , Bradbury , C , Russell , N H , Vyas , P , Burnett , A K , Grimwade , D , Hole , P S & Freeman , S D 2016 , ' Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia. ' , PLoS ONE , vol. 11 , no. 9 , e0163291 . https://doi.org/10.1371/journal.pone.0163291

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/1983/dd5a30dd-dd61-4255-bdc0-318d01adf36a
https://research-information.bris.ac.uk/en/publications/dd5a30dd-dd61-4255-bdc0-318d01adf36a
https://doi.org/10.1371/journal.pone.0163291
https://research-information.bris.ac.uk/ws/files/99278516/journal.pone.0163291.PDF
http://www.scopus.com/inward/record.url?scp=84992390478&partnerID=8YFLogxK

المؤلفون: Agathanggelou, Angelo, Weston, Victoria J, Perry, Tracey, Davies, Nicholas J, Skowronska, Anna, Payne, Daniel T, Fossey, John S, Oldreive, Ceri E, Wei, Wenbin, Pratt, Guy, Parry, Helen, Oscier, David, Coles, Steve J, Hole, Paul S, Darley, Richard L, McMahon, Michael, Hayes, John D, Moss, Paul, Stewart, Grant S, Taylor, A Malcolm R, Stankovic, Tatjana

مصطلحات موضوعية: WH Haemic and lymphatic systems. Haematology

وصف الملف: text

Relation: http://www.repository.uhblibrary.co.uk/id/eprint/1089/1/Targeting%20the%20Ataxia%20Telangiectasia%20Mutated-null%20phenotype%20in%20chronic%20lymphocytic%20leukemia%20with%20pro-oxidants.pdf; Agathanggelou, Angelo, Weston, Victoria J, Perry, Tracey, Davies, Nicholas J, Skowronska, Anna, Payne, Daniel T, Fossey, John S, Oldreive, Ceri E, Wei, Wenbin, Pratt, Guy, Parry, Helen, Oscier, David, Coles, Steve J, Hole, Paul S, Darley, Richard L, McMahon, Michael, Hayes, John D, Moss, Paul, Stewart, Grant S, Taylor, A Malcolm R and Stankovic, Tatjana (2015) Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants. Haematologica, 100 (8). pp. 1076-85. ISSN 1592-8721. This article is available to all UHB staff and students using a UHB OpenAthens Account. Register for OpenAthens here - http://openathens.nice.org.uk/

الاتاحة: http://www.repository.uhblibrary.co.uk/id/eprint/1089/
http://www.haematologica.org/content/100/8/1076.full.pdf+html
http://www.repository.uhblibrary.co.uk/id/eprint/1089/1/Targeting%20the%20Ataxia%20Telangiectasia%20Mutated-null%20phenotype%20in%20chronic%20lymphocytic%20leukemia%20with%20pro-oxidants.pdf
https://doi.org/10.3324/haematol.2014.115170

المؤلفون: Wadley, Alex J., Morgan, Rhys G., Darley, Richard L., Hole, Paul S., Coles, Steven J.

المساهمون: Hancock, John T., Conway, Myra E.

Relation: Wadley, Alex J., Morgan, Rhys G., Darley, Richard L. https://orca.cardiff.ac.uk/view/cardiffauthors/A008360O.html orcid:0000-0003-0879-0724 orcid:0000-0003-0879-0724, Hole, Paul S. and Coles, Steven J. 2019. Using flow cytometry to detect and measure intracellular thiol redox status in viable T cells from heterogeneous populations. Hancock, John T. and Conway, Myra E., eds. Redox-Mediated Signal Transduction: Methods and Protocols, Vol. 1990. Methods in Molecular Biology, New York, NY, USA: Humana Press, pp. 53-70. (10.1007/978-1-4939-9463-2_5 https://doi.org/10.1007/978-1-4939-9463-2_5)

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/131975/
https://doi.org/10.1007/978-1-4939-9463-2_5

المؤلفون: Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader, Darley, Richard L., Tonks, Alex

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/129344/1/ROBINSON,%20Andrew%20-%20Reactive%20oxygen%20species%20drive%20proliferation%20in%20acute%20myeloid%20leukemia%20via%20the%20glycolytic%20regulator%20PFKFB3.pdf; Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata https://orca.cardiff.ac.uk/view/cardiffauthors/A2302815N.html, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader https://orca.cardiff.ac.uk/view/cardiffauthors/A039332V.html, Darley, Richard L. https://orca.cardiff.ac.uk/view/cardiffauthors/A008360O.html orcid:0000-0003-0879-0724 orcid:0000-0003-0879-0724 and Tonks, Alex https://orca.cardiff.ac.uk/view/cardiffauthors/A016105H.html orcid:0000-0002-6073-4976 orcid:0000-0002-6073-4976 2020. Reactive oxygen species drive proliferation in acute myeloid leukemia via the glycolytic regulator PFKFB3. Cancer Research 80 (5) , pp. 937-949. 10.1158/0008-5472.CAN-19-1920 https://doi.org/10.1158/0008-5472.CAN-19-1920 file https://orca.cardiff.ac.uk/id/eprint/129344/1/ROBINSON,%20Andrew%20-%20Reactive%20oxygen%20species%20drive%20proliferation%20in%20acute%20myeloid%20leukemia%20via%20the%20glycolytic%20regulator%20PFKFB3.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/129344/
https://doi.org/10.1158/0008-5472.CAN-19-1920

المؤلفون: Jones, Nicholas, Vincent, Emma E., Felix, Lindsey C., Cronin, James G., Scott, Louis M., Hole, Paul S., Lacy, Paige, Thornton, Catherine A.

المصدر: Allergy; Jun2020, Vol. 75 Issue 6, p1361-1370, 10p, 1 Color Photograph, 1 Diagram, 4 Graphs

مصطلحات موضوعية: KREBS cycle, LACTATES, WARBURG Effect (Oncology), GRANULOCYTE-macrophage colony-stimulating factor, NICOTINAMIDE adenine dinucleotide phosphate, REACTIVE oxygen species, GLYCOLYSIS

المؤلفون: Hole, Paul S., Davies, Sara, Kreuser, Sandra, Omidvar, Nader, Tonks, Alex, Darley, Richard L.

مصطلحات موضوعية: hemic and lymphatic diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1061d9064d545cbd49060e1b0abb71b9

المؤلفون: Hole, Paul S., Zabkiewicz, Joanna, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul, Marquez, Nuria, Hills, Robert K., Burnett, Alan K., Tonks, Alex, Darley, Richard L.

Relation: Hole, P. S. et al. (2013) Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood , 122(19), pp. 3322-3330. (doi:10.1182/blood-2013-04-491944 ) (PMID:24089327)

الاتاحة: http://eprints.gla.ac.uk/123736/

المؤلفون: Hole, Paul S., Pearn, Lorna, Tonks, Amanda J., James, Philip E., Burnett, Alan K., Darley, Richard L., Tonks, Alex

المصدر: Blood; February 2010, Vol. 115 Issue: 6 p1238-1246, 9p

المؤلفون: Hole, Paul S., Pearn, Lorna, Tonks, Amanda J., James, Philip E., Burnett, Alan K., Darley, Richard L., Tonks, Alex

المصدر: Blood; February 2010, Vol. 115 Issue: 6 p1238-1246, 9p

المؤلفون: Hole, Paul S., Davies, Sara, Munje, Chinmay R, Kreuser, Sandra, Hills, Robert K., Omidvar, Nader, Knapper, Steven, Burnett, Alan K., Tonks, Alex, Darley, Richard L.

المصدر: Blood; December 2014, Vol. 124 Issue: 21 p785-785, 1p

المؤلفون: Hopkins, Goitseone Lucy, Robinson, Andrew J, Hole, Paul S, Darley, Richard L., Tonks, Alex

المصدر: Blood; December 2014, Vol. 124 Issue: 21 p2210-2210, 1p

المؤلفون: Hole, Paul S., Davies, Sara, Munje, Chinmay R, Kreuser, Sandra, Hills, Robert K., Omidvar, Nader, Knapper, Steven, Burnett, Alan K., Tonks, Alex, Darley, Richard L.

المصدر: Blood; December 2014, Vol. 124 Issue: 21 p785-785, 1p

المؤلفون: Hole, Paul S, Pearn, Lorna, James, Philip E, Burnett, Alan, Darley, Richard L, Tonks, Alex

المصدر: Blood; November 2008, Vol. 112 Issue: 11 p3797-3797, 1p

المؤلفون: Hole, Paul S, Pearn, Lorna, James, Philip E, Burnett, Alan, Darley, Richard L, Tonks, Alex

المصدر: Blood; November 2008, Vol. 112 Issue: 11 p3797-3797, 1p

المؤلفون: Hole, Paul Spencer

مصطلحات موضوعية: 616.15

الاتاحة: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584861