المؤلفون: Lynda S. Cook, Laura Zawadzke, Ramesh Padmanabha, Ping Wu, Margaret Casperson, Li Fan, Mona Kishnani, Deepa Calambur, Hofstead Sandra J

المصدر: Analytical Biochemistry. 314:243-252

مصطلحات موضوعية: Time Factors, Biophysics, Transferases (Other Substituted Phosphate Groups), Bacterial enzymes, Biology, N-Acetylglucosaminyltransferases, medicine.disease_cause, Biochemistry, Inhibitory Concentration 50, Bacterial Proteins, Cell Wall, Transferases, Escherichia coli, medicine, Inhibitory concentration 50, Plate assay, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Escherichia coli Proteins, Nucleosides, Cell Biology, Antimicrobial, Molecular biology, Anti-Bacterial Agents, Molecular Weight, Enzyme, chemistry, Electrophoresis, Polyacrylamide Gel, Membrane fraction, MurG enzyme, Bacterial Outer Membrane Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd7dc7293a579b40034c3417bc5f4de
https://doi.org/10.1016/s0003-2697(02)00622-x

المؤلفون: Pamela A. Trail, Harold Mastalerz, Raymond A. Firestone, David Willner, Hofstead Sandra J, Shirley J. Lasch, Dalton King, Gene M. Dubowchik

المصدر: Journal of Medicinal Chemistry. 45:4336-4343

مصطلحات موضوعية: Immunoconjugates, Stereochemistry, media_common.quotation_subject, Antineoplastic Agents, Peptide, Inhibitory Concentration 50, chemistry.chemical_compound, Amide, Drug Discovery, Tumor Cells, Cultured, medicine, Humans, Moiety, Doxorubicin, Internalization, media_common, chemistry.chemical_classification, Dipeptide, Hydrolysis, Antibodies, Monoclonal, Dipeptides, Hydrogen-Ion Concentration, Immunoconjugate, chemistry, Molecular Medicine, Dimerization, Linker, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29fb0884a9989d4a2ec907eb30cf07f
https://doi.org/10.1021/jm020149g

المؤلفون: Michael A. Walker, Shilpa Radia, Dalton King, Shirley J. Lasch, David Willner, Hofstead Sandra J, Gene M. Dubowchik, Harold Mastalerz, Raymond A. Firestone, Pamela A. Trail

المصدر: Bioorganic & Medicinal Chemistry Letters. 12:1529-1532

مصطلحات موضوعية: Immunoconjugates, Lung Neoplasms, medicine.drug_class, Stereochemistry, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, Peptide, Monoclonal antibody, Biochemistry, Cathepsin B, Inhibitory Concentration 50, chemistry.chemical_compound, Drug Discovery, Tumor Cells, Cultured, medicine, Humans, Doxorubicin, Sulfhydryl Compounds, Internalization, Molecular Biology, media_common, chemistry.chemical_classification, Binding Sites, Dipeptide, Organic Chemistry, Antibodies, Monoclonal, Stereoisomerism, Biological activity, Dipeptides, Immunoconjugate, chemistry, Chromatography, Gel, Molecular Medicine, Lysosomes, Dimerization, Half-Life, Conjugate, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933401d420d7b01374ef7d812e2fa84b
https://doi.org/10.1016/s0960-894x(02)00194-4

المؤلفون: David Willner, Gary R. Braslawsky, Greenfield Robert S, Shirley J. Lasch, Anna Maria Casazza, Hofstead Sandra J, Ingegerd Hellström, Raymond A. Firestone, Karl Erik Hellström, Pamela A. Trail, Arris J. Henderson, Takushi Kaneko, King Hd

المصدر: Journal of Controlled Release. 39:251-259

مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Chemistry, Pharmaceutical Science, Hydrazone, Biological activity, Endocytosis, Monoclonal antibody, Immunoconjugate, medicine.anatomical_structure, Biochemistry, In vivo, Lysosome, polycyclic compounds, medicine, Cancer research, Doxorubicin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c9bd0cf5063635932136c3bfc6102d4
https://doi.org/10.1016/0168-3659(95)00160-3

المؤلفون: David Willner, Greenfield Robert S, Shirley J. Lasch, Hofstead Sandra J, Pamela A. Trail, King Hd, Raymond A. Firestone, Takushi Kaneko, Braslawsky Gary R

المصدر: Bioconjugate Chemistry. 4:521-527

مصطلحات موضوعية: Lung Neoplasms, Stereochemistry, Biomedical Engineering, Pharmaceutical Science, Hydrazone, Bioengineering, Adenocarcinoma, Conjugated system, Epitopes, Mice, Drug Stability, medicine, Animals, Humans, Doxorubicin, Sulfhydryl Compounds, Cytotoxicity, Pharmacology, chemistry.chemical_classification, Chemistry, Immunotoxins, Organic Chemistry, Hydrazones, Antibodies, Monoclonal, Dithiothreitol, Cross-Linking Reagents, Covalent bond, Michael reaction, Oxidation-Reduction, Linker, Biotechnology, Conjugate, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d376fa23fd2adcf44afcec9d99262a04
https://doi.org/10.1021/bc00024a015

المؤلفون: Stella Huang, David R. Langley, Hofstead Sandra J, Kimberly L. Colson, Jerzy Golik, Daniel R. Schroeder, Steven E. Klohr, John E. Leet, Mike S. Lee

المصدر: Journal of the American Chemical Society. 115:8432-8443

مصطلحات موضوعية: Stereochemistry, General Chemistry, Chromophore, Biochemistry, Catalysis, Kedarcidin, chemistry.chemical_compound, Sodium borohydride, Colloid and Surface Chemistry, chemistry, Chromoprotein, Enediyne, Molecule, Derivatization, Chemical decomposition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::90a745ab913479f32eb69a3db7131049
https://doi.org/10.1021/ja00071a062

المؤلفون: Daniel R. Schroeder, John E. Leet, James A. Matson, Stella Huang, Jerzy Golik, Hofstead Sandra J, Kimberly L. Colson, Terrence W. Doyle, Steven E. Klohr

المصدر: ChemInform. 24

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Chromoprotein, medicine.drug_class, Stereochemistry, Kedarcidin chromophore, Antibiotics, medicine, General Medicine, Kedarcidin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::89e8e1e6dc97a7ad6643ff6eda49a318
https://doi.org/10.1002/chin.199303279

المؤلفون: John E. Leet, James A. Matson, Angela Y. Lee, Jerzy Golik, Hofstead Sandra J, Jon Clardy

المصدر: Tetrahedron Letters. 33:6107-6110

مصطلحات موضوعية: chemistry.chemical_classification, Amino sugar, Stereochemistry, Organic Chemistry, Absolute configuration, Nuclear magnetic resonance spectroscopy, Crystal structure, Biochemistry, Kedarcidin, chemistry.chemical_compound, chemistry, Kedarcidin chromophore, Drug Discovery, Moiety, Molecule

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3587db079840ea44f66b61d8793674a2
https://doi.org/10.1016/s0040-4039(00)60018-7

المؤلفون: Dubowchik, Gene M., Firestone, Raymond A., Padilla, Linda, Willner, David, Hofstead, Sandra J., Mosure, Kathleen, Knipe, Jay O., Lasch, Shirley J., Trail, Pamela A.

المصدر: Bioconjugate Chemistry ; volume 13, issue 4, page 855-869 ; ISSN 1043-1802 1520-4812

الاتاحة: http://dx.doi.org/10.1021/bc025536j
https://pubs.acs.org/doi/pdf/10.1021/bc025536j

المؤلفون: Wenying Li, Christopher L. Steele, Zizhuo Xing, Brian A. Dougherty, Hofstead Sandra J, Yijun Chen, Kin Sing Lam, Shu-Jen Chiang

المصدر: Archives of biochemistry and biophysics. 438(1)

مصطلحات موضوعية: Paclitaxel, Molecular Sequence Data, Biophysics, Phenylalanine, Phenylalanine ammonia-lyase, Protein Engineering, Biochemistry, chemistry.chemical_compound, Protein sequencing, stomatognathic system, Biosynthesis, Complementary DNA, parasitic diseases, Enzyme Stability, Escherichia coli, Amino Acid Sequence, Cloning, Molecular, Molecular Biology, Histidine, Phenylalanine Ammonia-Lyase, chemistry.chemical_classification, biology, Sequence Homology, Amino Acid, Active site, Recombinant Proteins, Enzyme Activation, Enzyme, chemistry, embryonic structures, biology.protein, Taxus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7c153b85ed3720df636551807a24cf
https://pubmed.ncbi.nlm.nih.gov/15878763

المؤلفون: David Willner, Hofstead Sandra J, Kathleen W. Mosure, Linda Padilla, Gene M. Dubowchik, Pamela A. Trail, Shirley J. Lasch, Raymond A. Firestone, Jay O. Knipe

المصدر: Bioconjugate chemistry. 13(4)

مصطلحات موضوعية: medicine.drug_class, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Monoclonal antibody, Cathepsin B, chemistry.chemical_compound, Lewis Blood Group Antigens, Antigen, Drug Stability, Antigens, Neoplasm, medicine, Tumor Cells, Cultured, Animals, Humans, Doxorubicin, Pharmacology, chemistry.chemical_classification, Dipeptide, Organic Chemistry, Antibodies, Monoclonal, Dipeptides, Molecular biology, Cysteine protease, In vitro, Enzymes, Rats, Kinetics, Enzyme, Cross-Linking Reagents, chemistry, Biochemistry, Lysosomes, Cell Division, Biotechnology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a77046ac1d541d0a19f366b28b419a3
https://pubmed.ncbi.nlm.nih.gov/12121142

المؤلفون: Michael A. Walker, Hofstead Sandra J, Gene M. Dubowchik, Raymond A. Firestone, Pamela A. Trail

المصدر: Bioorganicmedicinal chemistry letters. 12(2)

مصطلحات موضوعية: Immunoconjugates, Endosome, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biological activity, Endocytosis, Cleavage (embryo), Biochemistry, Cathepsin B, Immunoconjugate, Drug Discovery, medicine, Molecular Medicine, Camptothecin, Molecular Biology, Linker, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150ffe705af33cdfc50b6712523a0096
https://pubmed.ncbi.nlm.nih.gov/11755358

المؤلفون: Daniel R. Schroeder, James A. Matson, Jerzy Golik, Hofstead Sandra J, Kimberly L. Colson, Stella Huang, John E. Leet, Steven E. Klohr, Terrence W. Doyle

المصدر: Journal of the American Chemical Society. 114:7946-7948

مصطلحات موضوعية: chemistry.chemical_compound, Colloid and Surface Chemistry, Chemistry, Chromoprotein, Stereochemistry, Kedarcidin chromophore, General Chemistry, Chromophore, Biochemistry, Catalysis, Kedarcidin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b7967be240414d3aafd7b4e9543579df
https://doi.org/10.1021/ja00046a071

المؤلفون: Leet, John E., Schroeder, Daniel R., Langley, David R., Colson, Kimberly L., Huang, Stella, Klohr, Steven E., Lee, Mike S., Golil, Jerzy, Hofstead, Sandra J.

المصدر: Journal of the American Chemical Society ; volume 116, issue 5, page 2233-2233 ; ISSN 0002-7863 1520-5126

الاتاحة: http://dx.doi.org/10.1021/ja00084a112
https://pubs.acs.org/doi/pdf/10.1021/ja00084a112

المؤلفون: Anna Maria Casazza, David Willner, Ingegerd Hellström, Hofstead Sandra J, Shirley J. Lasch, Arris J. Henderson, Raymond A. Firestone, Pamela A. Trail, Hellstrom Karl Erik

المصدر: Science (New York, N.Y.). 261(5118)

مصطلحات موضوعية: Lung Neoplasms, medicine.drug_class, Ratón, medicine.medical_treatment, Mammary gland, Mice, Nude, Breast Neoplasms, Monoclonal antibody, Mice, Rats, Nude, Antigen, Antigens, Neoplasm, medicine, Carcinoma, Animals, Humans, Doxorubicin, Chemotherapy, Multidisciplinary, biology, business.industry, Immunotoxins, Antibodies, Monoclonal, Neoplasms, Experimental, medicine.disease, Rats, medicine.anatomical_structure, Immunology, Antigens, Surface, Colonic Neoplasms, Cancer research, biology.protein, Antibody, business, Neoplasm Transplantation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ad6d4b6d5f17d7e4031a8bcb09abd3
https://pubmed.ncbi.nlm.nih.gov/8327892

المؤلفون: James A. Matson, Hans Marquardt, Alison R. Malacko, Hofstead Sandra J

المصدر: The Journal of antibiotics. 45(8)

مصطلحات موضوعية: Size-exclusion chromatography, Ion chromatography, Molecular Sequence Data, Peptide, Naphthalenes, Kedarcidin, chemistry.chemical_compound, Chromoprotein, Drug Discovery, Actinomycetales, Amino Acid Sequence, Amino Acids, Chromatography, High Pressure Liquid, Pharmacology, chemistry.chemical_classification, Chromatography, Antibiotics, Antineoplastic, biology, Ion exchange, Proteins, Cycloparaffins, biology.organism_classification, Anti-Bacterial Agents, chemistry, Sephadex, Alkynes, Intercellular Signaling Peptides and Proteins, Enediynes, Isoelectric Focusing, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56638ccb6988b415aae092b8a21259ed
https://pubmed.ncbi.nlm.nih.gov/1399845