المؤلفون: Nicholas S. Luke, Michael J. DeVito, Christopher J. Portier, Hisham A. El-Masri

المصدر: Dose-Response, Vol 8 (2010)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1559-3258

URL الوصول: https://doaj.org/article/9ce61d6ef7b74e749e4eb2e61180bc17

المؤلفون: Clara Bay, Hisham A. El-Masri

المصدر: Toxicol Lett

مصطلحات موضوعية: Benzylamines, Fluorocarbons, Sulfonamides, Receptors, Cytoplasmic and Nuclear, General Medicine, Toxicology, Benzoates, Models, Biological, Article, Xenobiotics, Fatty Liver, Hepatocytes, Humans, Rifampin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daf4c110be915256033f10ad9326ff9
https://doi.org/10.1016/j.toxlet.2022.02.002

المؤلفون: J. Christopher Corton, Hisham A. El-Masri, Katharine L Korunes, John P. Rooney, Shihan He, Cari Martini, Jason M. Brown, Ying Liu, Katie Paul-Friedman, Jaleh Abedini

المصدر: Toxicol Pathol

مصطلحات موضوعية: medicine.medical_specialty, Liver tumor, Carcinogenesis, Bilirubin, 010501 environmental sciences, Toxicology, medicine.disease_cause, 01 natural sciences, Article, Pathology and Forensic Medicine, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Internal medicine, medicine, Animals, Aspartate Aminotransferases, Molecular Biology, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, Liver Neoplasms, Albumin, Alanine Transaminase, Cell Biology, medicine.disease, Rats, Endocrinology, Liver, chemistry, Toxicity, Alkaline phosphatase, Liver cancer, Genotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109534ce11b1c5e443c4b8b86111b301
https://doi.org/10.1177/0192623320960412

المؤلفون: Charles E. Wood, J. Christopher Corton, Thomas A. Hill, Jaleh Abedini, Hisham A. El-Masri, John P. Rooney

المصدر: Toxicol Sci

مصطلحات موضوعية: Liver tumor, Carcinogenesis, Gene Expression, Estrogen receptor, Biology, Toxicology, Bioinformatics, Aryl hydrocarbon receptor, medicine.disease, medicine.disease_cause, Article, Rats, Liver, biology.protein, medicine, Animals, Biomarker (medicine), Peroxisome proliferator-activated receptor alpha, Toxicogenomics, Liver cancer, DNA Damage, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1660890f26d35b0766ea70dabf383c
https://doi.org/10.1093/toxsci/kfaa102

المؤلفون: Sakshi Handa, Mary E. Gilbert, Hisham A. El-Masri, Iman Hassan

المصدر: Toxicol Sci

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Physiologically based pharmacokinetic modelling, Thyroid Hormones, Thyroid Gland, 010501 environmental sciences, Pharmacology, Toxicology, 01 natural sciences, Iodide Peroxidase, Article, 03 medical and health sciences, Thyroid peroxidase, In vivo, medicine, Animals, Computer Simulation, 0105 earth and related environmental sciences, ADME, biology, Chemistry, Thyroid, In vitro toxicology, Rats, 030104 developmental biology, medicine.anatomical_structure, Propylthiouracil, biology.protein, Hormone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859b2931d4a7b5ada2e3b3221a6d0e86
https://pubmed.ncbi.nlm.nih.gov/34117770

المؤلفون: John N. Snouwaert, Miroslav Stýblo, Beverly H. Koller, David J. Thomas, Christelle Douillet, Leigh A. Jania, Hisham A. El-Masri

المصدر: Environmental Health Perspectives. 128

مصطلحات موضوعية: inorganic chemicals, Chronic exposure, Methyltransferase, integumentary system, Inorganic arsenic, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, chemistry.chemical_element, Locus (genetics), Metabolism, Methylation, 010501 environmental sciences, Biology, Pharmacology, 01 natural sciences, 03 medical and health sciences, 0302 clinical medicine, chemistry, 030212 general & internal medicine, Arsenic, 0105 earth and related environmental sciences, Synteny

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a489b20dcbf050140f5ffc6c9fa06b40
https://doi.org/10.1289/ehp6943

المؤلفون: Nicholas S. Luke, Reeder Sams Ii, Michael J. Devito, Rory B. Conolly, Hisham A. El-masri

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://toxsci.oxfordjournals.org/content/115/1/253.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1026.2292; http://toxsci.oxfordjournals.org/content/115/1/253.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1026.2292
http://toxsci.oxfordjournals.org/content/115/1/253.full.pdf

المؤلفون: Marina V. Evans, Sean M. Dowd, Elaina M. Kenyon, Michael F. Hughes, Hisham A. El-masri

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://toxsci.oxfordjournals.org/content/104/2/250.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.553.7681; http://toxsci.oxfordjournals.org/content/104/2/250.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.553.7681
http://toxsci.oxfordjournals.org/content/104/2/250.full.pdf

المؤلفون: Mary E. Gilbert, Sigmund J. Degitz, Jermaine Ford, Patricia A. Kosian, Iman Hassan, Hisham A. El-Masri

المصدر: Toxicological Sciences. 160:57-73

مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_specialty, Time Factors, Offspring, Thyroid Gland, Gestational Age, Endocrine Disruptors, Toxicology, Iodide Peroxidase, 03 medical and health sciences, Pregnancy, Thyroid peroxidase, Internal medicine, Adverse Outcome Pathway, medicine, Animals, Computer Simulation, Rats, Long-Evans, Enzyme Inhibitors, Fetus, Adverse Outcome Pathways, Dose-Response Relationship, Drug, biology, business.industry, Thyroid, Brain, medicine.disease, Malformations of Cortical Development, Thyroxine, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Maternal Exposure, Propylthiouracil, Prenatal Exposure Delayed Effects, biology.protein, Female, business, Biomarkers, Hormone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f232ece1ad3133e9a65604d4d91de58
https://doi.org/10.1093/toxsci/kfx163

المؤلفون: Sakshi Handa, Mary E. Gilbert, Iman Hassan, Amanda Brennan, Hisham A. El-Masri, Katie Paul Friedman, Jermaine Ford

المصدر: Toxicol Sci

مصطلحات موضوعية: Male, endocrine system, Thyroid Hormones, Thyroid Gland, Pharmacology, Toxicology, Iodide Peroxidase, Article, fluids and secretions, Thyroid peroxidase, In vivo, medicine, Animals, Rats, Long-Evans, Methimazole, biology, Chemistry, Thyroid, food and beverages, hemic and immune systems, In vitro, Rats, medicine.anatomical_structure, Propylthiouracil, embryonic structures, Microsome, biology.protein, Ex vivo, Hormone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544a965a068f8271d48595434d0cd2ee
https://europepmc.org/articles/PMC9210949/

المؤلفون: Micah N. Jasper, Philip J. Bushnell, Sheppard A. Martin, Wendy M. Oshiro, Hisham A. El-Masri, Jermaine Ford

المصدر: Environmental Science & Technology. 50:3231-3238

مصطلحات موضوعية: Simulation error, Inhalation Exposure, Physiologically based pharmacokinetic modelling, Water contaminants, Chemistry, General Chemistry, Chemical interaction, Complex Mixtures, Models, Theoretical, 010501 environmental sciences, 01 natural sciences, Toxicokinetics, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Blood concentration, Environmental chemistry, Animals, Environmental Chemistry, Female, Rats, Long-Evans, Gasoline, 0105 earth and related environmental sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f03bcfa11ce584e21ee5a0c2bc5ac57
https://doi.org/10.1021/acs.est.5b05648

المؤلفون: Jeremy A. Leonard, Kristin Isaacs, Yu-Mei Tan, Mary E. Gilbert, Hisham A. El-Masri

المصدر: Toxicological Sciences. 151:57-70

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Physiologically based pharmacokinetic modelling, Thyroid Gland, 010501 environmental sciences, Pharmacology, Toxicology, Iodide Peroxidase, Models, Biological, Risk Assessment, 01 natural sciences, 03 medical and health sciences, Thyroid peroxidase, Internal medicine, medicine, Animals, Humans, Enzyme Inhibitors, 0105 earth and related environmental sciences, Triiodothyronine, biology, Chemistry, Thyroid, In vitro toxicology, Estimation of Margin of Exposure for Thyroid Peroxidase Inhibitors, Environmental exposure, High-Throughput Screening Assays, Rats, Thyroxine, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, biology.protein, Propylthiouracil, Biomarkers, Protein Binding, Hormone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dedc96dc3198003a3b3b948bd4413e2
https://doi.org/10.1093/toxsci/kfw022

المؤلفون: Yu-Mei Tan, Michael-Rock Goldsmith, Hisham A. El-Masri, Daniel T. Chang, Raina Brooks, Christopher M. Grulke, Stephen W. Edwards, Martin B. Phillips, Jeremy A. Leonard

المصدر: Environmental Health Perspectives

مصطلحات موضوعية: In Vitro Techniques, business.industry, Research, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, food and beverages, Bioinformatics, Risk Assessment, In vitro, High-Throughput Screening Assays, Workflow, Chemical screening, Pharmacokinetics, Adverse Outcome Pathway, Acetylcholinesterase, Humans, Medicine, Cholinesterase Inhibitors, Adverse effect, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8769c779b428a59f1da48f74659e4e
https://doi.org/10.1289/ehp.1409450

المؤلفون: Barbara A. Wetmore, Tina Bahadori, Hisham A. El-Masri, John F. Wambaugh, Elaine A. Cohen Hubal, Jon R. Sobus

المصدر: Journal of Exposure Science & Environmental Epidemiology

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, In vitro test, Computer science, Epidemiology, 010501 environmental sciences, Toxicology, 01 natural sciences, Models, Biological, Risk Assessment, Exposure modeling, 03 medical and health sciences, Human health, Credibility, medicine, Humans, Public health policy, 0105 earth and related environmental sciences, PBPK modeling, Public health, Public Health, Environmental and Occupational Health, Environmental Exposure, Pollution, Toxicokinetics, 030104 developmental biology, Risk analysis (engineering), Perspective, Public Health, Risk assessment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7abdeb52509879934b7088c57c432b
https://pubmed.ncbi.nlm.nih.gov/30116055

المؤلفون: Brian N. Chorley, Stephen W. Edwards, Sakshi Handa, Jaleh Abedini, Hisham A. El-Masri

المصدر: Toxicol Appl Pharmacol

مصطلحات موضوعية: 0301 basic medicine, Computational biology, Toxicology, Article, Xenobiotics, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Databases, Genetic, Animals, Gene Regulatory Networks, KEGG, Gene, Pharmacology, Pregnane X receptor, biology, Microarray analysis techniques, Gene Expression Profiling, Cytochrome P450, Aryl hydrocarbon receptor, Fatty acid omega-oxidation, Rats, Fatty Liver, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7e31e67b64d92ea846e765071eacaf
https://doi.org/10.1016/j.taap.2019.114757

المؤلفون: William K. Boyes, Philip J. Bushnell, Kyoungju Choi, Jerry L. Campbell, Eva D. McLanahan, Sheppard A. Martin, Hisham A. El-Masri, Harvey J. Clewell, William R. LeFew

المصدر: Inhalation Toxicology. 24:698-722

مصطلحات موضوعية: Developmental neurotoxicity, Physiologically based pharmacokinetic modelling, Neonatal rat, Ethanol, Inhalation, Drug Administration Routes, Health, Toxicology and Mutagenesis, Absorption (skin), Pharmacology, Toxicology, Models, Biological, Rats, Peak concentration, chemistry.chemical_compound, Animals, Newborn, chemistry, Pharmacokinetics, Pregnancy, Biofuels, mental disorders, Animals, Computer Simulation, Female, reproductive and urinary physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161b7f1264e60bb9301c6d2109eaf2c5
https://doi.org/10.3109/08958378.2012.712165

المؤلفون: John F. Wambaugh, Harvey J. Clewell, Paul M. Schlosser, Hisham A. El-Masri, Eva D. McLanahan, Leonid Kopylev, Lisa M. Sweeney

المصدر: Toxicological Sciences. 126:5-15

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Source code, Process (engineering), Computer science, media_common.quotation_subject, Probabilistic logic, Benchmarking, Pharmacology, Toxicology, Software portability, Risk analysis (engineering), Benchmark (surveying), Risk assessment, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa2ee3e6f223c46b9c02e5e8638873b2
https://doi.org/10.1093/toxsci/kfr295

المؤلفون: Hisham A. El-Masri

المصدر: Principles and Practice of Mixtures Toxicology

مصطلحات موضوعية: Chemical mixtures, Non-competitive inhibition, Chemistry, Organic chemistry, Righting reflex, Pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b3d6f5e5b51bbf98156c1cfdfbabcd40
https://doi.org/10.1002/9783527630196.ch7

المؤلفون: Elaina M. Kenyon, Sean M. Dowd, Michael F. Hughes, Marina V. Evans, Hisham A. El-Masri

المصدر: Toxicological Sciences. 104:250-260

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Dose-Response Relationship, Drug, Herbicides, Chemistry, Administration, Oral, Experimental data, Dimethylarsinic Acid, Pharmacology, Toxicology, Models, Biological, Sensitivity and Specificity, Oral gavage, Mice, Pharmacokinetics, Injections, Intravenous, Organ specific, Time course, Animals, Cacodylic Acid, Toxicokinetics, Female, Tissue Distribution, Biological system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9196895b485995d877073aafb29c17aa
https://doi.org/10.1093/toxsci/kfn080

المؤلفون: Hisham A. El-Masri

المصدر: Toxicology and Applied Pharmacology. 223:148-154

مصطلحات موضوعية: Pharmacology, Physiologically based pharmacokinetic modelling, Injury control, Computer science, Computational Biology, Experimental data, Poison control, Complex Mixtures, Models, Theoretical, Toxicology, Hazardous Substances, Regression, Modelling methods, Animals, Humans, Drug Interactions, Response surface methodology, Threshold Limit Values, Experimental methods, Biological system

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d680816f0b663505840f1049010a6f5d
https://doi.org/10.1016/j.taap.2006.07.009