المؤلفون: Mi-Hye Lee, Kathryn M. Appleton, Hesham M. El-Shewy, Mary G. Sorci-Thomas, Michael J. Thomas, Maria F. Lopes-Virella, Louis M. Luttrell, Samar M. Hammad, Richard L. Klein

المصدر: Journal of Lipid Research, Vol 58, Iss 2, Pp 325-338 (2017)

مصطلحات موضوعية: high density lipoprotein, sphingosine 1-phosphate, protein-fragment complementation assay, scavenger receptor BI, S1P receptors, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520314140; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/65f47730c6104614afd8fdba1e2a23ef

المؤلفون: Hesham M. El-Shewy, F. Kendall, William, Marcus Darrabie, Bradley H. Collins, Emmanuel C. Opara

المصدر: Cell Transplantation, Vol 13 (2004)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

URL الوصول: https://doaj.org/article/c83ff727782d4d91a0f93ca67d67faf4

المؤلفون: Louis M Luttrell, Moahad S Dar, Diane Gesty-Palmer, Hesham M El-Shewy, Katherine M Robinson, Courtney J Haycraft, Jeremy L Barth

المصدر: PLoS ONE, Vol 14, Iss 1, p e0204197 (2019)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1371/journal.pone.0204197; https://doaj.org/toc/1932-6203; https://doaj.org/article/a2dcf0467f014bbbb7d264e131ad3d2b

الاتاحة: https://doi.org/10.1371/journal.pone.0204197
https://doaj.org/article/a2dcf0467f014bbbb7d264e131ad3d2b

المؤلفون: Maria F. Lopes-Virella, Hesham M. El-Shewy, Michael J. Thomas, Kathryn M. Appleton, Louis M. Luttrell, Samar M. Hammad, Richard L. Klein, Mary G. Sorci-Thomas, Mi-Hye Lee

المصدر: Journal of Lipid Research, Vol 58, Iss 2, Pp 325-338 (2017)

مصطلحات موضوعية: 0301 basic medicine, media_common.quotation_subject, Nanotechnology, protein-fragment complementation assay, QD415-436, 030204 cardiovascular system & hematology, Biochemistry, Calcium in biology, 03 medical and health sciences, chemistry.chemical_compound, Organ Culture Techniques, 0302 clinical medicine, Endocrinology, Sphingosine, Cell surface receptor, Calcium flux, Animals, Humans, Internalization, Receptor, Sphingosine-1-Phosphate Receptors, Aorta, Research Articles, sphingosine 1-phosphate, S1PR1, media_common, nutritional and metabolic diseases, Biological Transport, scavenger receptor BI, Cell Biology, Scavenger Receptors, Class B, Rats, Cell biology, Receptors, Lysosphingolipid, HEK293 Cells, 030104 developmental biology, S1P receptors, chemistry, high density lipoprotein, Calcium, lipids (amino acids, peptides, and proteins), Lysophospholipids, Signal transduction, Lipoproteins, HDL, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee107c6cad9c3b56c46ed3b6688bc92
https://doi.org/10.1194/jlr.m070706

المؤلفون: Moahad Dar, Louis M. Luttrell, Hesham M. El-Shewy, Diane Gesty-Palmer, Jeremy L. Barth, Katherine M. Robinson, Courtney J. Haycraft

المصدر: PLoS ONE, Vol 14, Iss 1, p e0204197 (2019)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Microarrays, Cellular differentiation, Gene Expression, Datasets as Topic, Signal transduction, Extracellular matrix, Mice, 0302 clinical medicine, Animal Cells, Bone Density, Osteogenesis, Medicine and Health Sciences, Gene Regulatory Networks, Connective Tissue Cells, Oligonucleotide Array Sequence Analysis, Regulation of gene expression, 0303 health sciences, Multidisciplinary, Wnt signaling pathway, Signaling cascades, Cell Differentiation, Osteoblast, 3T3 Cells, Osteoblast Differentiation, Extracellular Matrix, Cell biology, Autocrine Communication, Bioassays and Physiological Analysis, medicine.anatomical_structure, RANKL, Connective Tissue, 030220 oncology & carcinogenesis, Medicine, Bone Remodeling, Cellular Types, Anatomy, Network Analysis, Research Article, musculoskeletal diseases, Computer and Information Sciences, Science, 030209 endocrinology & metabolism, Biology, Research and Analysis Methods, 03 medical and health sciences, Paracrine signalling, Paracrine Communication, Genetics, medicine, Animals, Gene Regulation, Autocrine signalling, 030304 developmental biology, Osteoblasts, Gene Expression Profiling, Mesenchymal stem cell, Biology and Life Sciences, Signaling Networks, Gene expression profiling, Biological Tissue, 030104 developmental biology, TGF-beta signaling cascade, biology.protein, Transcriptome, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc80c9daa6c3e01d525f779c56969b0d
https://doaj.org/article/a2dcf0467f014bbbb7d264e131ad3d2b

المؤلفون: Erika E. Büllesbach, Hesham M. El-Shewy, Louis M. Luttrell, Stuart Parnham, Dzmitry Fedarovich

المصدر: The FASEB Journal. 32

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Chemistry, Genetics, STIM1, Sphingosine-1-phosphate, Molecular Biology, Biochemistry, Store-operated calcium entry, Biotechnology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e3c20b6902f5eae610d83df506d3650e
https://doi.org/10.1096/fasebj.2018.32.1_supplement.815.10

المؤلفون: Kathryn M. Appleton, Thomas A. Morinelli, Mi-Hye Lee, Parker C. Wilson, Hesham M. El-Shewy, Louis M. Luttrell, Yuri K. Peterson, Ayad A. Jaffa

المصدر: Journal of Biological Chemistry. 288:18872-18884

مصطلحات موضوعية: Receptor, Bradykinin B2, Arrestins, Myocytes, Smooth Muscle, Pharmacology, Biology, Ligands, Biochemistry, Losartan, Receptor, Angiotensin, Type 1, Rats, Sprague-Dawley, GTP-Binding Proteins, Enzyme-linked receptor, Functional selectivity, Animals, Humans, 5-HT5A receptor, cardiovascular diseases, Bradykinin receptor, Receptor, Molecular Biology, Aorta, Angiotensin II receptor type 1, Dose-Response Relationship, Drug, urogenital system, Angiotensin II, Hemodynamics, Cell Biology, biological factors, Rats, HEK293 Cells, cardiovascular system, Calcium, Kallikreins, Estrogen-related receptor gamma, Dimerization, Allosteric Site, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb891c55cdc2e13d9380fb222c1dbea
https://doi.org/10.1074/jbc.m113.472381

المؤلفون: Samar M. Hammad, Ayad A. Jaffa, Mi Hye Lee, Hesham M. El-Shewy, Parker C. Wilson, Louis M. Luttrell, Mimi Sohn

المصدر: Molecular Endocrinology. 26:833-845

مصطلحات موضوعية: Transcriptional Activation, MAP Kinase Signaling System, Recombinant Fusion Proteins, Pertussis toxin, chemistry.chemical_compound, Transactivation, Endocrinology, Sphingosine, Animals, Humans, Protein Isoforms, Diabetic Nephropathies, Gene Silencing, RNA, Messenger, Sphingosine-1-phosphate, RNA, Small Interfering, Receptor, Sphingosine-1-Phosphate Receptors, Molecular Biology, Cells, Cultured, Dyslipidemias, Original Research, biology, Cell Membrane, Connective Tissue Growth Factor, General Medicine, Molecular biology, Rats, Up-Regulation, Lipoproteins, LDL, CTGF, Phosphotransferases (Alcohol Group Acceptor), Protein Transport, Receptors, Lysosphingolipid, chemistry, Sphingosine kinase 1, Mesangial Cells, biology.protein, lipids (amino acids, peptides, and proteins), Lysophospholipids, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05e733525a9c5503fad2e420e758f92
https://doi.org/10.1210/me.2011-1261

المؤلفون: Hesham M. El-Shewy, Lina M. Obeid, Souzan A. Abdelsamie, Mi Hye Lee, Ayad A. Jaffa, Kazuyuki Kitatani, Louis M. Luttrell, Abdelmohsen M. al Qalam, Viviana Anelli

المصدر: Molecular Endocrinology. 25:2144-2156

مصطلحات موضوعية: Indoles, Recombinant Fusion Proteins, Green Fluorescent Proteins, Enzyme Activators, Protein Kinase C beta, Mitogen-activated protein kinase kinase, Receptor, IGF Type 2, Receptor, IGF Type 1, Diglycerides, Maleimides, chemistry.chemical_compound, Endocrinology, Insulin-Like Growth Factor II, Sphingosine, Humans, Molecular Biology, Protein Kinase C, Protein kinase C, Original Research, Cell Proliferation, MAP kinase kinase kinase, Phospholipase C, biology, General Medicine, Lipid signaling, Molecular biology, Cell biology, Enzyme Activation, Phosphotransferases (Alcohol Group Acceptor), Protein Transport, HEK293 Cells, chemistry, Sphingosine kinase 1, Gene Knockdown Techniques, Type C Phospholipases, Mesangial Cells, biology.protein, Tetradecanoylphorbol Acetate, RNA Interference, Lysophospholipids, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dae924569d9a9234f70b9cca6dcd9f4
https://doi.org/10.1210/me.2011-0101

المؤلفون: Christopher R. Gault, Arelis Salas, Joshua J. Oaks, Yusuf Baran, Besim Ogretmen, Robert K. Stuart, Ramasamy Santhanam, Guido Marcucci, Danilo Perrotti, Suriyan Ponnusamy, Elif Apohan, Lina M. Obeid, Hesham M. El-Shewy, Daniel J. Fernandes, Marisa Meyers-Needham, Sandeep Mahajan, Sahar A. Saddoughi, Shanmugam Panneer Selvam, Can E. Senkal, R. David Sentelle, Charles D. Smith

المساهمون: TR119193, Baran, Yusuf, Izmir Institute of Technology. Molecular Biology and Genetics

المصدر: Blood. 117:5941-5952

مصطلحات موضوعية: Cancer cells, Immunology, Phosphatase, Fusion Proteins, bcr-abl, Mice, SCID, Protein degradation, Biochemistry, Piperazines, Dephosphorylation, Mice, chemistry.chemical_compound, Sphingosine, Cell Line, Tumor, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, Protein Phosphatase 2, Sphingosine-1-phosphate, Phosphorylation, RNA, Small Interfering, Myeloid Neoplasia, biology, Chronic myeloid leukemia, Ubiquitination, Cell Biology, Hematology, Small interfering RNA, Phosphotransferases (Alcohol Group Acceptor), Receptors, Lysosphingolipid, Pyrimidines, Imatinib mesylate, chemistry, Sphingosine kinase 1, Nilotinib, Drug Resistance, Neoplasm, Drug resistance, Benzamides, Imatinib Mesylate, Cancer research, biology.protein, Lysophospholipids, Signal Transduction, medicine.drug, K562 cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ba74c280d6d383ca8042691be9ea57
https://doi.org/10.1182/blood-2010-08-300772

المؤلفون: Monika Gooz, Joo-Seob Keum, Mi-Hye Lee, Ayad A. Jaffa, Louis M. Luttrell, Hesham M. El-Shewy, Deirdre K. Luttrell, Bing Wang, Rany T. Abdallah

المصدر: Journal of Biological Chemistry. 285:35206-35215

مصطلحات موضوعية: Transcriptional Activation, EGF Family of Proteins, medicine.medical_specialty, Vascular smooth muscle, MAP Kinase Signaling System, High-molecular-weight kininogen, Bradykinin, ADAM17 Protein, Biology, Amphiregulin, Biochemistry, Muscle, Smooth, Vascular, Rats, Sprague-Dawley, chemistry.chemical_compound, Epidermal growth factor, Internal medicine, Diabetes Mellitus, medicine, Animals, Humans, Receptor, PAR-2, Receptor, PAR-1, Protease-activated receptor, Molecular Biology, Glycoproteins, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, urogenital system, Prekallikrein, Cell Biology, Kallikrein, Rats, Cell biology, Enzyme Activation, ErbB Receptors, ADAM Proteins, HEK293 Cells, Endocrinology, chemistry, Intercellular Signaling Peptides and Proteins, Kallikreins, Receptors, Thrombin, Signal transduction, Signal Transduction, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924550c1a958e4fa176c6dc2b5cea123
https://doi.org/10.1074/jbc.m110.171769

المؤلفون: Hesham M. El-Shewy, Richard L. Klein, Mi-Hye Lee, Louis M. Luttrell, Deirdre K. Luttrell

المصدر: Biochemistry. 47:11682-11692

مصطلحات موضوعية: MAP Kinase Signaling System, Biology, Models, Biological, Biochemistry, Article, Cell Line, Downregulation and upregulation, Animals, Humans, Small GTPase, RNA, Small Interfering, Protein kinase A, Cells, Cultured, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Base Sequence, Adiponectin, Recombinant Proteins, Rats, Cell biology, Enzyme Activation, src-Family Kinases, ras Proteins, Cancer research, Adiponectin binding, RNA Interference, Rap1, Receptors, Adiponectin, Signal transduction, Cell Division, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f7ffe91eaf26a0a9bdc76dc263b40b
https://doi.org/10.1021/bi801451f

المؤلفون: Mi-Hye Lee, Deirdre K. Luttrell, Hesham M. El-Shewy, Louis M. Luttrell

المصدر: Journal of Biological Chemistry. 283:2088-2097

مصطلحات موضوعية: Transcription, Genetic, Arrestins, MAP Kinase Signaling System, Biology, Biochemistry, Receptor, Angiotensin, Type 1, Cell Line, Heterotrimeric G protein, Homologous desensitization, Arrestin, Enzyme-linked receptor, Animals, Humans, Protein Isoforms, Vasoconstrictor Agents, 5-HT5A receptor, Receptor, Molecular Biology, beta-Arrestins, Oligonucleotide Array Sequence Analysis, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Beta-Arrestins, Angiotensin II, Gene Expression Profiling, Cell Biology, MAP Kinase Kinase Kinases, Molecular biology, Rats, Up-Regulation, Enzyme Activation, GTP-Binding Protein alpha Subunits, Gq-G11, raf Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43006c5859af3fbc5e19df9f1c4e7172
https://doi.org/10.1074/jbc.m706892200

المؤلفون: Michael W. Brands, Ayad A. Jaffa, Wayne R. Fitzgibbon, Sara M. Garrett, Hesham M. El-Shewy, Louis M. Luttrell, Parker C. Wilson

مصطلحات موضوعية: Male, medicine.medical_specialty, chemistry.chemical_element, Blood Pressure, Calcium, Calcium in biology, Rats, Sprague-Dawley, chemistry.chemical_compound, Endocrinology, Sphingosine, Internal medicine, medicine, Animals, Humans, Molecular Biology, Original Research, Voltage-dependent calcium channel, biology, Calcium channel, Angiotensin II, Cell Membrane, T-type calcium channel, General Medicine, Cell biology, Enzyme Activation, Mice, Inbred C57BL, Phosphotransferases (Alcohol Group Acceptor), Receptors, Lysosphingolipid, HEK293 Cells, chemistry, Sphingosine kinase 1, Chronic Disease, Hypertension, biology.protein, Calcium Channels, Lysophospholipids, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8a0608c49e243054f8892b5945efd0
https://europepmc.org/articles/PMC4447644/

المؤلفون: Parker C. Wilson, Louis M. Luttrell, Hesham M. El-Shewy

المصدر: The FASEB Journal. 29

مصطلحات موضوعية: Vascular smooth muscle, biology, Sphingosine, Voltage-dependent calcium channel, Chemistry, Calcium channel, Biochemistry, Angiotensin II, Calcium in biology, Cell biology, chemistry.chemical_compound, Sphingosine kinase 1, Genetics, biology.protein, lipids (amino acids, peptides, and proteins), Molecular Biology, Intracellular, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a4eb0babda1c6a8e829d4be32babf4b8
https://doi.org/10.1096/fasebj.29.1_supplement.715.34

المؤلفون: Hesham M. El-Shewy, Lina M. Obeid, Mi-Hye Lee, Ayad A. Jaffa, Korey R. Johnson, Louis M. Luttrell

المصدر: Journal of Biological Chemistry. 281:31399-31407

مصطلحات موضوعية: Transcriptional Activation, G protein, Sphingosine-1-phosphate receptor, Green Fluorescent Proteins, Sphingosine kinase, Biochemistry, Transactivation, Somatomedins, Sphingosine, Heterotrimeric G protein, Animals, Humans, Molecular Biology, G protein-coupled receptor, Mitogen-Activated Protein Kinase 1, G protein-coupled receptor kinase, Mitogen-Activated Protein Kinase 3, biology, Cell Biology, Molecular biology, Protein Structure, Tertiary, Cell biology, Enzyme Activation, Phosphotransferases (Alcohol Group Acceptor), Gq alpha subunit, biology.protein, Lysophospholipids, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44665c8a2edeba67afbdc132ca56f3c6
https://doi.org/10.1074/jbc.m605339200

المؤلفون: Mi-Hye Lee, Deirdre K. Luttrell, Hesham M. El-Shewy, Farahdiba Jafri, Margaret M. Kelly, Louis M. Luttrell

المصدر: Journal of Biological Chemistry. 281:19346-19357

مصطلحات موضوعية: G protein-coupled receptor kinase, Beta-Arrestins, Tachykinin receptor 1, 5-HT5A receptor, Cell Biology, Signal transduction, Biology, Receptor, Protein kinase A, Molecular Biology, Biochemistry, G protein-coupled receptor, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::84b5bfa686af9140cbb43c287078bc46
https://doi.org/10.1074/jbc.m512643200

المؤلفون: Emmanuel C. Opara, Marcus D. Darrabie, Hesham M. El-Shewy, William F. Kendall

المصدر: Journal of Microencapsulation. 21:821-828

مصطلحات موضوعية: Alginate microspheres, Materials science, Alginates, Drug Compounding, Islets of Langerhans Transplantation, Pharmaceutical Science, Bioengineering, Microsphere, Islets of Langerhans, chemistry.chemical_compound, Colloid and Surface Chemistry, Glucuronic Acid, Pharmaceutical technology, Humans, Particle Size, Physical and Theoretical Chemistry, Chromatography, business.industry, Organic Chemistry, Glucuronic acid, Microspheres, Biotechnology, Transplantation, Diabetes Mellitus, Type 1, chemistry, Type i diabetes, Particle size, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f85ab0df845e4536bc94fdd2c67e0be
https://doi.org/10.1080/02652040400015452

المؤلفون: Salah Abdel-aleem, Khalifa El-Dawy, James D. St. Louis, James E. Lowe, Hesham M. El-Shewy, Steven C. Hendrickson, Doris A. Taylor

المصدر: Molecular and Cellular Biochemistry. 180:95-103

مصطلحات موضوعية: chemistry.chemical_classification, medicine.medical_specialty, Fatty acid metabolism, Clinical Biochemistry, Fatty acid, Cell Biology, General Medicine, Biology, Carbohydrate metabolism, Pyruvate dehydrogenase complex, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, medicine, Extracellular, Glycolysis, Carnitine, Molecular Biology, Beta oxidation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::88afba15f5e84ba8830d6deba938da04
https://doi.org/10.1023/a:1006843107922

المؤلفون: Rany T. Abdallah, Joo-Seob Keum, Hesham M. El-Shewy, Mi-Hye Lee, Bing Wang, Monika Gooz, Deirdre K. Luttrell, Louis M. Luttrell, Ayad A. Jaffa

مصطلحات موضوعية: Additions and Corrections, Cell Biology, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e1c1d0360de985db099ce113ab7782
https://europepmc.org/articles/PMC3123125/