المؤلفون: Gonzalez-Visiedo, Miguel, Herzog, Roland W., Munoz-Melero, Maite, Blessinger, Sophia A., Cook-Mills, Joan M., Daniell, Henry, Markusic, David M.

المصدر: 7 ; Viruses ; 16

مصطلحات موضوعية: Dentistry, adeno-associated virus, food allergy, immune tolerance, liver gene transfer, peanut allergy

وصف الملف: application/pdf

Relation: https://repository.upenn.edu/handle/20.500.14332/60757

الاتاحة: https://repository.upenn.edu/handle/20.500.14332/60757
https://hdl.handle.net/20.500.14332/60757

المؤلفون: Li, Ning, Kumar, Sandeep R. P., Cao, Di, Munoz-Melero, Maite, Arisa, Sreevani, Brian, Bridget A., Greenwood, Calista M., Yamada, Kentaro, Duan, Dongsheng, Herzog, Roland W.

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Adeno-associated virus, CD8 T cell, TLR9, IL-1, Muscle

وصف الملف: application/pdf

Relation: Viruses; https://hdl.handle.net/1805/44521

الاتاحة: https://hdl.handle.net/1805/44521

المؤلفون: Zhou, Yuan, Zhang, Chen, Xiao, Weidong, Herzog, Roland W., Han, Renzhi

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Dependovirus, Genetic therapy, Myocardium, Sarcolemma

وصف الملف: application/pdf

Relation: Nature Communications; Zhou Y, Zhang C, Xiao W, Herzog RW, Han R. Systemic delivery of full-length dystrophin in Duchenne muscular dystrophy mice. Nat Commun. 2024;15(1):6141. Published 2024 Jul 21. doi:10.1038/s41467-024-50569-6; https://hdl.handle.net/1805/43354

الاتاحة: https://hdl.handle.net/1805/43354

المؤلفون: Kodippili, Kasun, Hakim, Chady H., Burke, Matthew J., Yue, Yongping, Teixeira, James A., Zhang, Keqing, Yao, Gang, Babu, Gopal J., Herzog, Roland W., Duan, Dongsheng

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Duchenne muscular dystrophy, DMD, SERCA2a, AAV, Canine model, Muscle function, Treg, Tyrosine mutant AAV9, Sarcoplasmic reticulum, Extensor carpi ulnaris

وصف الملف: application/pdf

Relation: Molecular Therapy: Methods & Clinical Development; Kodippili K, Hakim CH, Burke MJ, et al. SERCA2a overexpression improves muscle function in a canine Duchenne muscular dystrophy model. Mol Ther Methods Clin Dev. 2024;32(2):101268. Published 2024 May 20. doi:10.1016/j.omtm.2024.101268; https://hdl.handle.net/1805/42972

الاتاحة: https://hdl.handle.net/1805/42972

المؤلفون: Zhang, Junping, Yu, Xiangping, Chrzanowski, Matthew, Tian, Jiahe, Pouchnik, Derek, Guo, Ping, Herzog, Roland W., Xiao, Weidong

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Adeno-associated virus, AAV, TMCA-AAVseq, Noncanonical AAV genomes, Molecular configuration, Library construction

وصف الملف: application/pdf

Relation: Molecular Therapy - Methods & Clinical Development; Zhang J, Yu X, Chrzanowski M, et al. Thorough molecular configuration analysis of noncanonical AAV genomes in AAV vector preparations. Mol Ther Methods Clin Dev. 2024;32(1):101215. Published 2024 Feb 19. doi:10.1016/j.omtm.2024.101215; https://hdl.handle.net/1805/41784

الاتاحة: https://hdl.handle.net/1805/41784

المؤلفون: Rana, Jyoti, Herzog, Roland W., Muñoz-Melero, Maite, Yamada, Kentaro, Kumar, Sandeep R. P., Lam, Anh K., Markusic, David M., Duan, Dongsheng, Terhorst, Cox, Byrne, Barry J., Corti, Manuela, Biswas, Moanaro

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Gene therapy, Adeno-associated virus (AAV), Immune suppression, Redosing, Re-administration, Capsid, Transgene

وصف الملف: application/pdf

Relation: Molecular Therapy - Methods & Clinical Development; Rana J, Herzog RW, Muñoz-Melero M, et al. B cell focused transient immune suppression protocol for efficient AAV readministration to the liver. Mol Ther Methods Clin Dev. 2024;32(1):101216. Published 2024 Feb 20. doi:10.1016/j.omtm.2024.101216; https://hdl.handle.net/1805/41819

الاتاحة: https://hdl.handle.net/1805/41819

المؤلفون: Zhang, Junping, Frabutt, Dylan A., Chrzanowski, Matthew, Li, Ning, Miller, Lohra M., Tian, Jiahe, Mulcrone, Patrick L., Lam, Anh K., Draper, Benjamin E., Jarrold, Martin F., Herzog, Roland W., Xiao, Weidong

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Adeno-associated virus, Self-complementary AAV vectors, Covalently closed-end double-stranded AAV, Transduction, Genome integrity

وصف الملف: application/pdf

Relation: Molecular Therapy - Methods & Clinical Development; Zhang J, Frabutt DA, Chrzanowski M, et al. A novel class of self-complementary AAV vectors with multiple advantages based on cceAAV lacking mutant ITR. Mol Ther Methods Clin Dev. 2024;32(1):101206. Published 2024 Feb 3. doi:10.1016/j.omtm.2024.101206; https://hdl.handle.net/1805/41387

الاتاحة: https://hdl.handle.net/1805/41387

المؤلفون: Kumar, Sandeep R.P., Biswas, Moanaro, Cao, Di, Arisa, Sreevani, Muñoz-Melero, Maite, Lam, Anh K., Piñeros, Annie R., Kapur, Reuben, Kaisho, Tsuneyasu, Kaufman, Randal J., Xiao, Weidong, Shayakhmetov, Dmitry M., Terhorst, Cox, de Jong, Ype P., Herzog, Roland W.

المساهمون: National Heart Lung and Blood Institute, National Institute of Allergy and Infectious Diseases

المصدر: Molecular Therapy ; volume 32, issue 2, page 325-339 ; ISSN 1525-0016

الاتاحة: http://dx.doi.org/10.1016/j.ymthe.2023.11.029
https://api.elsevier.com/content/article/PII:S1525001623006627?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1525001623006627?httpAccept=text/plain

المؤلفون: Bertolini, Thais B., Herzog, Roland W., Kumar, Sandeep R.P., Sherman, Alexandra, Rana, Jyoti, Kaczmarek, Radoslaw, Yamada, Kentaro, Arisa, Sreevani, Lillicrap, David, Terhorst, Cox, Daniell, Henry, Biswas, Moanaro

المصدر: Cellular Immunology ; 385

مصطلحات موضوعية: Dentistry, Forkhead Transcription Factors

وصف الملف: application/pdf

Relation: https://repository.upenn.edu/handle/20.500.14332/60748

الاتاحة: https://repository.upenn.edu/handle/20.500.14332/60748
https://hdl.handle.net/20.500.14332/60748

المؤلفون: Butterfield, John S.S., Li, Xin, Arisa, Sreevani, Kwon, Kwang-Chul, Daniell, Henry, Herzog, Roland W.

المصدر: Cellular Immunology ; 391-392

مصطلحات موضوعية: Dentistry, Gene therapy, Hemophilia, Oral tolerance

وصف الملف: application/pdf

Relation: https://repository.upenn.edu/handle/20.500.14332/60753

الاتاحة: https://repository.upenn.edu/handle/20.500.14332/60753
https://hdl.handle.net/20.500.14332/60753

المؤلفون: Biswas, Moanaro, So, Kaman, Bertolini, Thais B., Krishnan, Preethi, Rana, Jyoti, Muñoz-Melero, Maite, Syed, Farooq, Kumar, Sandeep R. P., Gao, Hongyu, Xuei, Xiaoling, Terhorst, Cox, Daniell, Henry, Cao, Sha, Herzog, Roland W.

المصدر: Frontiers in Immunology ; 14

مصطلحات موضوعية: Dentistry, antidrug antibodies (ADA), FoxP3+ regulatory T cells, latency associated peptide (LAP), oral tolerance, single cell RNA and transcriptome sequencing

وصف الملف: application/pdf

Relation: https://repository.upenn.edu/handle/20.500.14332/60747

الاتاحة: https://repository.upenn.edu/handle/20.500.14332/60747
https://hdl.handle.net/20.500.14332/60747

المؤلفون: Kaczmarek, Radoslaw, Piñeros, Annie R., Patterson, Paige E., Bertolini, Thais B., Perrin, George Q., Sherman, Alexandra, Born, Jameson, Arisa, Sreevani, Arvin, Matthew C., Kamocka, Malgorzata M., Martinez, Michelle M., Dunn, Kenneth W., Quinn, Sean M., Morris, Johnathan J., Wilhelm, Amelia R., Kaisho, Tsuneyasu, Munoz-Melero, Maite, Biswas, Moanaro, Kaplan, Mark H., Linnemann, Amelia K., George, Lindsey A., Camire, Rodney M., Herzog, Roland W.

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Factor VIII, Hemostatics, Hemophilia A, Ovalbumin

وصف الملف: application/pdf

Relation: Blood; Kaczmarek R, Piñeros AR, Patterson PE, et al. Factor VIII trafficking to CD4+ T cells shapes its immunogenicity and requires several types of antigen-presenting cells. Blood. 2023;142(3):290-305. doi:10.1182/blood.2022018937; https://hdl.handle.net/1805/38372

الاتاحة: https://hdl.handle.net/1805/38372

المؤلفون: Zuo, Yuanbojiao, Zhang, Chen, Zhou, Yuan, Li, Haiwen, Xiao, Weidong, Herzog, Roland W., Xu, Jie, Zhang, Jifeng, Chen, Y. Eugene, Han, Renzhi

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: ANGPTL3, Cholesterol, Base editing, Base editor, Cardiovascular disease, CVD, Triglyceride

وصف الملف: application/pdf

Relation: Cell & Bioscience; Zuo Y, Zhang C, Zhou Y, et al. Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice. Cell Biosci. 2023;13(1):109. Published 2023 Jun 15. doi:10.1186/s13578-023-01036-0; https://hdl.handle.net/1805/38032

الاتاحة: https://hdl.handle.net/1805/38032

المؤلفون: Mulcrone, Patrick L., Lam, Anh K., Frabutt, Dylan, Zhang, Junping, Chrzanowski, Matthew, Herzog, Roland W., Xiao, Weidon

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Biotechnology, Chemical biology, Molecular biology, Chemistry

وصف الملف: application/pdf

Relation: Scientific Reports; Mulcrone PL, Lam AK, Frabutt D, et al. Chemical modification of AAV9 capsid with N-ethyl maleimide alters vector tissue tropism. Sci Rep. 2023;13(1):8436. Published 2023 May 25. doi:10.1038/s41598-023-35547-0; https://hdl.handle.net/1805/37519

الاتاحة: https://hdl.handle.net/1805/37519

المؤلفون: Sherman, Alexandra, Bertolini, Thais B., Arisa, Sreevani, Herzog, Roland W., Kaczmarek, Radoslaw

المساهمون: Pediatrics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Anaphylaxis, Factor IX, Hemophilia B, Immune tolerance, Inhibitor

وصف الملف: application/pdf

Relation: Research and Practice in Thrombosis and Haemostasis; Sherman A, Bertolini TB, Arisa S, Herzog RW, Kaczmarek R. Factor IX administration in the skin primes inhibitor formation and sensitizes hemophilia B mice to systemic factor IX administration. Res Pract Thromb Haemost. 2023;7(8):102248. Published 2023 Nov 4. doi:10.1016/j.rpth.2023.102248; https://hdl.handle.net/1805/40915

الاتاحة: https://hdl.handle.net/1805/40915

المؤلفون: Li, Xin, Miller, Lohra Mickelle, Chrzanowski, Matthew, Tian, Jiahe, Jarrold, Martin F., Herzog, Roland W., Xiao, Weidong, Draper, Benjamin, Zhang, Junping

المصدر: Frontiers in Bioengineering and Biotechnology ; volume 11 ; ISSN 2296-4185

الاتاحة: http://dx.doi.org/10.3389/fbioe.2023.1327433
https://www.frontiersin.org/articles/10.3389/fbioe.2023.1327433/full

المؤلفون: Herzog, Roland W., VandenDriessche, Thierry, Ozelo, Margareth C.

المصدر: Molecular Therapy ; volume 31, issue 1, page 1-2 ; ISSN 1525-0016

الاتاحة: http://dx.doi.org/10.1016/j.ymthe.2022.12.001
https://api.elsevier.com/content/article/PII:S1525001622007055?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1525001622007055?httpAccept=text/plain

المؤلفون: Pierce, Glenn F., Herzog, Roland W.

المصدر: Molecular Therapy ; volume 31, issue 4, page 919-920 ; ISSN 1525-0016

الاتاحة: http://dx.doi.org/10.1016/j.ymthe.2023.03.001
https://api.elsevier.com/content/article/PII:S1525001623001223?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1525001623001223?httpAccept=text/plain

المؤلفون: Chen, Zhouji, Herzog, Roland W., Kaufman, Randal J.

المساهمون: F. Hoffmann-La Roche, NHLBI

المصدر: Journal of Thrombosis and Haemostasis ; volume 21, issue 12, page 3329-3341 ; ISSN 1538-7836

الاتاحة: http://dx.doi.org/10.1016/j.jtha.2023.10.005
https://api.elsevier.com/content/article/PII:S1538783623007705?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1538783623007705?httpAccept=text/plain

المؤلفون: Valentino, Leonard A., Ozelo, Margareth C., Herzog, Roland W., Key, Nigel S., Pishko, Allyson M., Ragni, Margaret V., Samelson-Jones, Benjamin J., Lillicrap, David

المساهمون: BioMarin Pharmaceutical

المصدر: Journal of Thrombosis and Haemostasis ; volume 21, issue 11, page 3033-3044 ; ISSN 1538-7836

الاتاحة: http://dx.doi.org/10.1016/j.jtha.2023.05.011
https://api.elsevier.com/content/article/PII:S1538783623004245?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1538783623004245?httpAccept=text/plain