المؤلفون: Kirsten Raun, Sara G. Vienberg, Birgitte Andersen, Tina Møller Tagmose, Xin Zhao, Xujia Zhang, Henning Thøgersen, Kristian Sass-Ørum, Ann Maria Kruse Hansen, Dan Han, Kirsten Lykkegaard, Goa Tingqing

المصدر: Biochemical Journal. 475:2985-2996

مصطلحات موضوعية: 0301 basic medicine, FGF21, medicine.medical_treatment, Glucose uptake, 030209 endocrinology & metabolism, Fibroblast growth factor, Biochemistry, law.invention, Mice, 03 medical and health sciences, 0302 clinical medicine, Species Specificity, law, medicine, Animals, Humans, Cholesterol 7-alpha-Hydroxylase, Receptor, Molecular Biology, Chemistry, FGF15, Growth factor, Cell Biology, Receptors, Fibroblast Growth Factor, Rats, Cell biology, Fibroblast Growth Factors, Glucose, HEK293 Cells, 030104 developmental biology, Fibroblast growth factor receptor, Hepatocytes, Recombinant DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e7aa51ad1b5bc4f782e5fe16ff20b4
https://doi.org/10.1042/bcj20180555

المؤلفون: Jesper Lau, Patrik Petersson, Jennifer K. Field, Melvin R. Euerby, Henning Thøgersen

مصطلحات موضوعية: RM, Static Electricity, Peptide, Buffers, 010402 general chemistry, 01 natural sciences, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Phase (matter), QD, Amino Acid Sequence, Acetonitrile, chemistry.chemical_classification, Chromatography, Reverse-Phase, Principal Component Analysis, Chromatography, Hydrogen bond, Ligand, 010401 analytical chemistry, Organic Chemistry, Hydrogen Bonding, General Medicine, Reversed-phase chromatography, Combinatorial chemistry, Small molecule, 0104 chemical sciences, chemistry, Peptides, Selectivity, Hydrophobic and Hydrophilic Interactions

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9966eac4d1426623b6e678933eca0a6b
https://strathprints.strath.ac.uk/69134/1/Field_etal_JCA_2019_Investigation_into_reversed_phase_chromatography_peptide_separation_systems_part_I.pdf

المؤلفون: Allan Christian Shaw, Erik Vernet, Marie Østergaard Pedersen, Henning Thøgersen

المصدر: Protein expression and purification. 170

مصطلحات موضوعية: 0106 biological sciences, Proteases, Dipeptidases, medicine.medical_treatment, Genetic Vectors, Gene Expression, Peptide, Protein Engineering, 01 natural sciences, Aminopeptidase, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Glucagon-Like Peptide 1, 010608 biotechnology, medicine, Escherichia coli, Humans, Cloning, Molecular, 030304 developmental biology, Enzyme Assays, chemistry.chemical_classification, 0303 health sciences, Dipeptide, Protease, biology, Lactococcus lactis, biology.organism_classification, Glucagon, Fusion protein, Recombinant Proteins, Amino acid, body regions, Kinetics, chemistry, Biochemistry, Amino Acid Substitution, Proteolysis, Mutagenesis, Site-Directed, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023ddabb40b6ecd758b2e2ecc633ece1
https://pubmed.ncbi.nlm.nih.gov/32007557

المؤلفون: Leonardo De Maria, Stephanie Hennen, Lars Linderoth, Alberto Oddo, Jacob Kofoed, Henning Thøgersen, James N. McGuire, Sofia Mortensen, Steffen Reedtz-Runge

المصدر: Biochemistry. 57(28)

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, endocrine system, Molecular model, Stereochemistry, Protein domain, Beta sheet, Peptide, Molecular Dynamics Simulation, Crystallography, X-Ray, Biochemistry, Glucagon-Like Peptide-1 Receptor, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Protein Domains, Glucagon-Like Peptide 1, Animals, Humans, Amino Acid Sequence, Receptor, Peptide sequence, chemistry.chemical_classification, Chemistry, digestive, oral, and skin physiology, In vitro, 030104 developmental biology, 030220 oncology & carcinogenesis, Exenatide, Protein Conformation, beta-Strand, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a2c2a8509432bcc0645673e757005b
https://pubmed.ncbi.nlm.nih.gov/29877701

المؤلفون: Henning Thøgersen, Leif Christensen, Helle Birk Olsen, Cecilia Nilsson, Ulrich Sensfuss, Thomas Kruse Hansen, Kilian Conde-Frieboes, Kirsten Raun, Kirsten Dahl, Birgit Sehested Hansen, Jane Spetzler, Birgitte Schjellerup Wulff, Jesper Lau

المصدر: Journal of Medicinal Chemistry. 55:1969-1977

مصطلحات موضوعية: Male, Melanocyte-stimulating hormone, Stereochemistry, Injections, Subcutaneous, Rats, Sprague-Dawley, Eating, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Receptor, chemistry.chemical_classification, Fatty Acids, Fatty acid, Rats, Amino acid, Melanocortin 4 receptor, Solubility, chemistry, Biochemistry, alpha-MSH, Receptor, Melanocortin, Type 4, Molecular Medicine, Anti-Obesity Agents, Long chain fatty acid, Melanocortin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506c57b49d0e739285b222ba20d7d798
https://doi.org/10.1021/jm201489a

المؤلفون: Kirsten Raun, Birgit Sehested Hansen, Henning Thøgersen, Michael Ankersen, Kilian Conde-Frieboes, Birgitte Schjellerup Wulff, Jens Breinholt

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:1459-1463

مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Rats, Sprague-Dawley, Piperidines, Ethers, Cyclic, In vivo, Internal medicine, Drug Discovery, medicine, Animals, Receptor, Molecular Biology, Molecular Structure, Chemistry, Organic Chemistry, Antagonist, In vitro, Rats, Melanocortin 4 receptor, Endocrinology, Anorectic, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin, Receptor, Melanocortin, Type 1, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfcb4e219be3a3cbf37118ab9dedd4f
https://doi.org/10.1016/j.bmcl.2011.01.011

المؤلفون: Per Franklin Nielsen, N. L. Johansen, Kjeld Madsen, Lotte Bjerre Knudsen, Henrik Agersoe, Henning Thøgersen, Michael Wilken

المصدر: Journal of Medicinal Chemistry. 50:6126-6132

مصطلحات موضوعية: Swine, Stereochemistry, Molecular Sequence Data, Peptide, Glucagon-Like Peptide-1 Receptor, Cell Line, Structure-Activity Relationship, chemistry.chemical_compound, Glucagon-Like Peptide 1, Cricetinae, Drug Discovery, Cyclic AMP, Receptors, Glucagon, Peptide synthesis, Animals, Humans, Structure–activity relationship, Potency, Amino Acid Sequence, Peptide sequence, Glucagon-like peptide 1 receptor, chemistry.chemical_classification, Chemistry, Fatty Acids, Fatty acid, Liraglutide, Ligand (biochemistry), Biochemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d56f5c7bd00b8530ddcbf29aae58002
https://doi.org/10.1021/jm070861j

المؤلفون: Susann Schimmer, Henning Thøgersen, Steffen Runge, Sanne Möller Knudsen, Jesper Lau, Rainer Rudolph, Kjeld Madsen, Jan Oschmann, Claus Bekker Jeppesen, Christine Bruun Schiødt

المصدر: Biochemistry. 46:5830-5840

مصطلحات موضوعية: Protein Denaturation, Protein Folding, Circular dichroism, Hot Temperature, Molecular Sequence Data, Ligands, Biochemistry, Glucagon-Like Peptide-1 Receptor, Protein structure, Glucagon-Like Peptide 1, Cricetinae, Receptors, Glucagon, Extracellular, Animals, Humans, Potency, Amino Acid Sequence, Receptor, Peptide sequence, Calorimetry, Differential Scanning, Venoms, Chemistry, Circular Dichroism, Transmembrane protein, Protein Structure, Tertiary, Spectrometry, Fluorescence, Biophysics, Exenatide, Protein folding, Peptides, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2178a15d6eab146d6bd8b086f4dfbba9
https://doi.org/10.1021/bi062309m

المؤلفون: Kent Bondensgaard, Henning Thøgersen, Birgitte Schjellerup Wulff, Robert P. Bywater, Birgit Sehested Hansen, Michael Ankersen

المصدر: Journal of Medicinal Chemistry. 47:888-899

مصطلحات موضوعية: Models, Molecular, Indoles, Stereochemistry, Molecular Sequence Data, Tetrazoles, Sequence alignment, Ligands, Receptor, Angiotensin, Type 1, Cell Line, Receptors, G-Protein-Coupled, Conserved sequence, Turn (biochemistry), Molecular recognition, Piperidines, Cricetinae, Drug Discovery, Animals, Spiro Compounds, Amino Acid Sequence, Binding site, Receptors, Ghrelin, Conserved Sequence, G protein-coupled receptor, Binding Sites, Chemistry, Biphenyl Compounds, Ligand (biochemistry), Biphenyl compound, Receptors, Serotonin, Indans, Receptor, Melanocortin, Type 4, Molecular Medicine, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9080a39b78a525510867fae72ff47fc2
https://doi.org/10.1021/jm0309452

المؤلفون: Mikael Kofod-Hansen, Henning Thøgersen, Bernd Peschke

المصدر: The Journal of Organic Chemistry. 67:1227-1232

مصطلحات موضوعية: Models, Molecular, chemistry.chemical_classification, Magnetic Resonance Spectroscopy, Molecular Structure, Protein Conformation, Chemistry, Stereochemistry, Organic Chemistry, Chemistry, Organic, Substituent, Peptoid, Tripeptide, Peptides, Cyclic, Catalysis, Cyclic peptide, chemistry.chemical_compound, Cyclization, Nucleophilic aromatic substitution, Peptide synthesis, Side chain, Peptides, Conformational isomerism, Chromatography, High Pressure Liquid, Nitrobenzenes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7da5d59aefa5372a1d9e069f86b3ed
https://doi.org/10.1021/jo016269y

المؤلفون: Birgit Sehested Hansen, Henning Thøgersen, Hans Petersen, Jesper Lau, Brett Watson, Thomas Kruse Hansen, Kjeld Madsen, Bernd Peschke, Nils Langeland Johansen, Michael Ankersen

المصدر: European Journal of Medicinal Chemistry. 34:363-380

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Dipeptide, Stereochemistry, Peptidomimetic, Organic Chemistry, Peptide, General Medicine, Peptide hormone, Amino acid, chemistry.chemical_compound, chemistry, Biochemistry, Growth hormone secretagogue, Drug Discovery, Ipamorelin, GHRP-6

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4664c04f23887695914a35a3bd96a8b6
https://doi.org/10.1016/s0223-5234(99)80086-5

المؤلفون: Kjeld Madsen, Jesper Lau, Birgit Sehested Hansen, Karin Kramer Nielsen, Thomas Kruse Hansen, Nils Langeland Johansen, Henning Thøgersen, Behrend F. Lundt, Peter H. Andersen, Michael Ankersen, Bernd Peschke, Kirsten Raun

المصدر: Journal of Medicinal Chemistry. 41:3705-3714

مصطلحات موضوعية: Male, Models, Molecular, medicine.medical_specialty, Magnetic Resonance Spectroscopy, Swine, Drug Evaluation, Preclinical, Administration, Oral, Biological Availability, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Pharmacokinetics, In vivo, Oral administration, Internal medicine, Drug Discovery, medicine, Animals, Potency, Structure–activity relationship, Ipamorelin, Molecular Mimicry, Hormones, Rats, Bioavailability, Endocrinology, chemistry, Growth Hormone, Pituitary Gland, Injections, Intravenous, Molecular Medicine, Female, Oligopeptides, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f483c6cf8fe3143ed56face8c2eed8
https://doi.org/10.1021/jm980197u

المؤلفون: Henning Thøgersen, Thomas Kruse Hansen, Birgit Sehested Hansen

المصدر: Bioorganic & Medicinal Chemistry Letters. 7:2951-2954

مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Biphenyl derivatives, Pharmaceutical Science, Peptide hormone, Growth hormone, Biochemistry, Chemical synthesis, Thiophene derivatives, Bioavailability, chemistry.chemical_compound, Oral administration, Drug Discovery, Lactam, Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::272ce1d9708f7bd9538883712e8f20f6
https://doi.org/10.1016/s0960-894x(97)10115-9

المؤلفون: Kjeld Madsen, Nils Langeland Johansen, Rosario González-Muñiz, Ibon Alkorta, Henning Thøgersen, Peter D. Suzdak, M. Teresa García-López, M. José Domínguez, Rosario Herranz

المصدر: Letters in Peptide Science. 1:269-276

مصطلحات موضوعية: Steric effects, chemistry.chemical_compound, Dipeptide, Indolizidines, Molecular model, chemistry, Stereochemistry, Diastereomer, Peptide bond, Moiety, Indolizidine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dd9f08b60d75ce8581a3ee7be0b849f2
https://doi.org/10.1007/bf00119767

المؤلفون: Anni Larnkjær, Henning Thøgersen, Gunilla Olivecrona, P. Østergaard, Anders Nykjaer

المصدر: Larnkjaer, A, Nykjaer, A, Olivecrona, G, Thøgersen, H-M V & Ostergaard, P B 1995, ' Structure of heparin fragments with high affinity for lipoprotein lipase and inhibition of lipoprotein lipase binding to alpha 2-macroglobulin-receptor/low-density-lipoprotein-receptor-related protein by heparin fragments ', Biochemical Journal, vol. 307 ( Pt 1), pp. 205-14 .
Europe PubMed Central

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular Sequence Data, Oligosaccharides, Plasma protein binding, Biochemistry, Chromatography, Affinity, alpha-2-Macroglobulin, Sulfation, Affinity chromatography, medicine, Amino Acid Sequence, Receptors, Immunologic, Molecular Biology, Lipoprotein lipase, Chromatography, biology, Heparin, Chemistry, Cell Biology, Lipoprotein Lipase, Carbohydrate Sequence, Depression, Chemical, LDL receptor, biology.protein, Low Density Lipoprotein Receptor-Related Protein-1, Research Article, Protein Binding, Lipoprotein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ce4226b718ce1df5b8263b2ea284b2
https://doi.org/10.1042/bj3070205

المؤلفون: Christian Beyschau Andersen, Matthew R. Hicks, Valeria Vetri, Brian Vandahl, Henrik Rahbek-Nielsen, Henning Thøgersen, Ida Bukh Thøgersen, Jan Johannes Enghild, Louise Serpell, Christian Rischel, Daniel Erik Otzen

مصطلحات موضوعية: Uncategorised value

Relation: 10779/uos.23344985.v1; https://figshare.com/articles/journal_contribution/Glucagon_Fibril_Polymorphism_Reflects_Differences_in_Protofilament_Backbone_Structure/23344985

الاتاحة: https://figshare.com/articles/journal_contribution/Glucagon_Fibril_Polymorphism_Reflects_Differences_in_Protofilament_Backbone_Structure/23344985

المؤلفون: Jesper Lau, Knud Erik Andersen, Hans Petersen, Elaine C. Lee, Henning Thøgersen, Mukund S. Chorghade, Behrend F. Lundt, Per Olaf Sorensen, Mikael Begtrup

المصدر: Tetrahedron. 50:8699-8710

مصطلحات موضوعية: Tiagabine, Stereochemistry, Metabolite, Organic Chemistry, Nuclear magnetic resonance spectroscopy, Biochemistry, Hydroxylation, Acylation, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, Thiolactone, GABA Uptake Inhibitors, Demethylation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a1c39621928f30c69d865e0efa04bc9
https://doi.org/10.1016/s0040-4020(01)85345-x

المؤلفون: Rainer Rudolph, Kjeld Madsen, Jesper Lau, Henning Thøgersen, Steffen Runge

المصدر: The Journal of biological chemistry. 283(17)

مصطلحات موضوعية: endocrine system, Magnetic Resonance Spectroscopy, Stereochemistry, Protein Conformation, Molecular Sequence Data, Peptide, Plasma protein binding, Biology, Crystallography, X-Ray, Ligands, Biochemistry, Glucagon-Like Peptide-1 Receptor, Protein Structure, Secondary, Protein structure, Insulin-Secreting Cells, Receptors, Glucagon, Glucose homeostasis, Humans, Amino Acid Sequence, Receptor, Molecular Biology, Peptide sequence, chemistry.chemical_classification, Sequence Homology, Amino Acid, Venoms, digestive, oral, and skin physiology, Cell Membrane, Tryptophan, Cell Biology, Ligand (biochemistry), Amino acid, chemistry, Exenatide, Peptides, hormones, hormone substitutes, and hormone antagonists, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55d1794582825701e737bbec3e5f3ce
https://pubmed.ncbi.nlm.nih.gov/18287102

المؤلفون: Jannie Fuhlendorff, N L Johansen, Thue W. Schwartz, S G Melberg, Henning Thøgersen

المصدر: Journal of Biological Chemistry. 265:11706-11712

مصطلحات موضوعية: Chemistry, Stereochemistry, Neuropeptide, Cell Biology, Peptide hormone, Neuropeptide Y receptor, Antiparallel (biochemistry), Biochemistry, humanities, mental disorders, Pancreatic polypeptide, Binding site, Receptor, Molecular Biology, Protein secondary structure

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::96fc4425d631d8367213b713616fbbf6
https://doi.org/10.1016/s0021-9258(19)38454-6

المؤلفون: Birgit Sehested Hansen, Nils Langeland Johansen, Peter H. Andersen, Henning Thøgersen, Kjeld Madsen

المصدر: American Peptide Symposia ISBN: 0792351606

مصطلحات موضوعية: chemistry.chemical_compound, Growth hormone-releasing peptide, Design synthesis, chemistry, Biochemistry, Peptide bond, Gh release, Secretion, Biological activity, GHRP-6, Growth hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3952fe3a117c8c2e8f75558c4eb3b69a
https://doi.org/10.1007/0-306-46862-x_278