المؤلفون: Helmut Schmidhammer, Mahmoud Al-Khrasani, Susanna Fürst, Mariana Spetea

المصدر: Molecules, Vol 28, Iss 12, p 4761 (2023)

مصطلحات موضوعية: pain, analgesia, opioid receptors, peripheral analgesia, peripherally restricted opioids, morphine, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/12/4761; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/e78b265ba0fe4ef5af3c578155bc1697

المؤلفون: Mariana Spetea, Helmut Schmidhammer

المصدر: ACS Central Science, Vol 5, Iss 6, Pp 936-938 (2019)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/f967031552f1481c947001f9da7bfff5

المؤلفون: Kristina Puls, Helmut Schmidhammer, Gerhard Wolber, Mariana Spetea

المصدر: Molecules, Vol 27, Iss 3, p 919 (2022)

مصطلحات موضوعية: GPCR, opioid receptor, HS-731, peripheral opioid agonist, analgesia, binding, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/3/919; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/e601a0d177024170ab74c548d581e29a

المؤلفون: Mariana Spetea, Helmut Schmidhammer

المصدر: Molecules, Vol 26, Iss 18, p 5677 (2021)

مصطلحات موضوعية: morphine, morphinans, 14-alkoxymorphinans, opioid agonist, multifunctional opioid ligands, drug design, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/18/5677; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/bdfc1c2374f1462b816b0c69d231a953

المؤلفون: Mariana Spetea, Helmut Schmidhammer

المصدر: Molecules, Vol 25, Iss 23, p 5658 (2020)

مصطلحات موضوعية: n/a, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/23/5658; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/bce50dd707fc4705a21274f2bc5a7e2d

المؤلفون: Helmut Schmidhammer, Filippo Erli, Elena Guerrieri, Mariana Spetea

المصدر: Molecules, Vol 25, Iss 21, p 5092 (2020)

مصطلحات موضوعية: kappa opioid receptor, diphenethylamines, design and synthesis, structure–activity relationships, agonist, partial agonist, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/21/5092; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/8978bee2f6f94aca9d878d3b8e7d2144

المؤلفون: Susanna Fürst, Zoltán S. Zádori, Ferenc Zádor, Kornél Király, Mihály Balogh, Szilvia B. László, Barbara Hutka, Amir Mohammadzadeh, Chiara Calabrese, Anna Rita Galambos, Pál Riba, Patrizia Romualdi, Sándor Benyhe, Júlia Timár, Helmut Schmidhammer, Mariana Spetea, Mahmoud Al-Khrasani

المصدر: Molecules, Vol 25, Iss 11, p 2473 (2020)

مصطلحات موضوعية: peripheral µ-opioid receptors, analgesia, peripheral analgesic tolerance, dysbiosis, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/11/2473; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/ccf64e1b1f134e5ab7211ab01a32dca6

المؤلفون: Roberta Lattanzi, Silvia Rief, Helmut Schmidhammer, Lucia Negri, Mariana Spetea

المصدر: Frontiers in Pharmacology, Vol 9 (2018)

مصطلحات موضوعية: pain, analgesia, constipation, opioid agonist, opioid receptor, morphinans, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2018.01002/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/80c75f410e494a228656f14578ece010

المؤلفون: Tanila Ben Haddou, Szabolcs Béni, Sándor Hosztafi, Davide Malfacini, Girolamo Calo, Helmut Schmidhammer, Mariana Spetea

المصدر: PLoS ONE, Vol 9, Iss 6, p e99231 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24919067/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/a73325779fbe481cbacb806a8cd04d23

المؤلفون: Damian Bartuzi, Ewa Kędzierska, Agnieszka A. Kaczor, Helmut Schmidhammer, Dariusz Matosiuk

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 22; Pages: 8463

مصطلحات موضوعية: allosteric modulation, antinociceptive compounds, behavioral studies, molecular dynamics, opioid receptors

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Informatics; https://dx.doi.org/10.3390/ijms21228463

الاتاحة: https://doi.org/10.3390/ijms21228463

المؤلفون: Helmut Schmidhammer, Mariana Spetea

المصدر: Molecules
Molecules, Vol 26, Iss 5677, p 5677 (2021)

مصطلحات موضوعية: Morphinan, drug design, Analgesic, multifunctional opioid ligands, Receptors, Opioid, mu, Pharmaceutical Science, Review, Bioinformatics, Analytical Chemistry, chemistry.chemical_compound, QD241-441, opioid agonist, Drug Discovery, Medicine, Animals, pain, Physical and Theoretical Chemistry, antinociception, Analgesics, business.industry, Organic Chemistry, Chronic pain, morphine, medicine.disease, Analgesics, Opioid, side effects, chemistry, Opioid, Morphinans, Chemistry (miscellaneous), Oxymorphone, Morphine, Molecular Medicine, structure–activity relationships, business, Oxycodone, medicine.drug, Buprenorphine, 14-alkoxymorphinans, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1cf07a6fa869dbdc27e6906d25ac3a
http://europepmc.org/articles/PMC8464912

المؤلفون: Mariana, Spetea, Helmut, Schmidhammer

المصدر: Handbook of experimental pharmacology. 271

مصطلحات موضوعية: Analgesics, Opioid, Structure-Activity Relationship, Receptors, Opioid, kappa, Humans, Ligands, Dynorphins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6f20bad4897982002392efb1fa92d3ad
https://pubmed.ncbi.nlm.nih.gov/33454858

المؤلفون: Mariana Spetea, Helmut Schmidhammer

المصدر: The Kappa Opioid Receptor ISBN: 9783030890735

مصطلحات موضوعية: Agonist, 0303 health sciences, medicine.drug_class, business.industry, Antagonist, Dynorphin, Pharmacology, Partial agonist, κ-opioid receptor, Small molecule, 03 medical and health sciences, 0302 clinical medicine, Opioid, medicine, Receptor, business, 030217 neurology & neurosurgery, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c1ff9425b166a8a89bdba635ae4f926
https://doi.org/10.1007/164_2020_431

المؤلفون: Mariana Spetea, Helmut Schmidhammer, Sándor Benyhe, Mihaly Balogh, Mahmoud Al-Khrasani, Pál Riba, Chiara Calabrese, Susanna Fürst, Szilvia B. László, Amir Mohammadzadeh, Zoltán S. Zádori, Ferenc Zádor, Anna Rita Galambos, Kornél Király, Julia Timár, Patrizia Romualdi, Barbara Hutka

المساهمون: Furst S., Zadori Z.S., Zador F., Kiraly K., Balogh M., Laszlo S.B., Hutka B., Mohammadzadeh A., Calabrese C., Galambos A.R., Riba P., Romualdi P., Benyhe S., Timar J., Schmidhammer H., Spetea M., Al-Khrasani M.

المصدر: Molecules
Molecules, Vol 25, Iss 2473, p 2473 (2020)

مصطلحات موضوعية: Analgesic, Receptors, Opioid, mu, Pharmaceutical Science, Pain, Sensory system, Review, Bioinformatics, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, 0302 clinical medicine, lcsh:Organic chemistry, Drug Discovery, medicine, Animals, Humans, Pain Management, Peripheral µ-opioid receptors, Physical and Theoretical Chemistry, Receptor, 030304 developmental biology, 0303 health sciences, business.industry, Organic Chemistry, Peripheral analgesic tolerance, dysbiosis, Receptor Desensitization, medicine.disease, Peripheral, Dysbiosi, Analgesics, Opioid, Opioid, Chemistry (miscellaneous), Molecular Medicine, μ-opioid receptor, Analgesia, business, Dysbiosis, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9729a11ecb5453a299b4a2a97ce583f6
http://hdl.handle.net/11585/796310

المؤلفون: Maria, Dumitrascuta, Tanila, Ben Haddou, Elena, Guerrieri, Stefan M, Noha, Lea, Schläfer, Helmut, Schmidhammer, Mariana, Spetea

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Analgesics, Brief Article, Receptors, Opioid, kappa, Cell Membrane, Receptors, Opioid, mu, CHO Cells, Enkephalin, Ala(2)-MePhe(4)-Gly(5), Ligands, Molecular Docking Simulation, Structure-Activity Relationship, Cricetulus, Morphinans, Guanosine 5'-O-(3-Thiotriphosphate), Receptors, Opioid, delta, mental disorders, Animals

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::79b5b040f59c3345eb1b02f4505a6477
https://pubmed.ncbi.nlm.nih.gov/29053268

المؤلفون: Annemieke Madder, Ann Van Eeckhaut, Steven Ballet, Jessica Andrade, Bruno Van Mele, Tanila Ben Haddou, Mariana Spetea, Edith Oyen, Lynne J. Waddington, Helmut Schmidhammer, Charlotte Martin, Richard Hoogenboom, Yannick Van Wanseele, James Gardiner

المساهمون: Chemistry, WE Academic Unit, Faculty of Sciences and Bioengineering Sciences, Pharmaceutical and Pharmacological Sciences, Faculty of Medicine and Pharmacy, Experimental Pharmacology, Pharmaceutical Chemistry, Drug Analysis and Drug Information, Materials and Chemistry, Physical Chemistry and Polymer Science

مصطلحات موضوعية: Drug, Materials science, Polymers and Plastics, Controlled-release, media_common.quotation_subject, Pain, Peptide, 02 engineering and technology, Pharmacology, 010402 general chemistry, 01 natural sciences, Catalysis, Biomaterials, Colloid and Surface Chemistry, 14-Methoxymetopon, In vivo, medicine, Materials Chemistry, media_common, chemistry.chemical_classification, Peptide hydrogels, opioids, 021001 nanoscience & nanotechnology, Controlled release, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, chemistry, Opioid, Self-healing hydrogels, Drug delivery, 0210 nano-technology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd75a5762ca5eee66d59b4ccdbbe2c31
https://hdl.handle.net/20.500.14017/dc045575-e7d8-4770-b457-d4f8a4be4ae5

المؤلفون: Helmut Schmidhammer, Verena Stempfer, Elena Porcù, Attila Sipos, Antal Udvardy, Giampietro Viola, Sándor Antus, Giuseppe Basso, Ernest Hamel, Attila Cs. Bényei, Ruoli Bai

المصدر: European Journal of Medicinal Chemistry. 84:476-490

مصطلحات موضوعية: Noscapine, Cell cycle checkpoint, Suzuki reaction, Apoptosis, Jurkat cells, Article, Cell cycle arrest, Dose-Response Relationship, HeLa, Jurkat Cells, Structure-Activity Relationship, Drug Discovery, Humans, Structure–activity relationship, Antimicrotubule agents, Pharmacology, Dose-Response Relationship, Drug, biology, Chemistry, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, General Medicine, Cell cycle, biology.organism_classification, Cell biology, Molecular Docking Simulation, Tubulin, Biochemistry, Cancer cell, Apoptosis Regulatory Proteins, HeLa Cells, biology.protein, Drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91cff5ce26cc83c72b0df8d389c9269
https://doi.org/10.1016/j.ejmech.2014.07.050

المؤلفون: Resat Cinar, Mária Szücs, Gabriella Fábián, Orsolya Kékesi, Erika Birkas, Helmut Schmidhammer

المصدر: Current Pharmaceutical Design. 19:7348-7354

مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, Biology, Ligand (biochemistry), 14-Methoxymetopon, Etorphine, Opioid, Drug Discovery, medicine, Functional selectivity, Signal transduction, Receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b91bed4ef5ebb311e55672bee4b75aaf
https://doi.org/10.2174/138161281942140105161245

المؤلفون: Helmut Schmidhammer, Muhammad Faheem Asim, Mariana Spetea, Gerhard Wolber

المصدر: Current Pharmaceutical Design. 19:7415-7434

مصطلحات موضوعية: Pharmacology, Agonist, medicine.drug_class, Drug discovery, Chemistry, Partial agonist, nervous system, Opioid, In vivo, mental disorders, Drug Discovery, polycyclic compounds, medicine, Pharmacophore, Receptor, Opioid peptide, human activities, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::44bda4af4da86356f68fdfb2028c00bc
https://doi.org/10.2174/13816128113199990362

المؤلفون: Stefan M. Noha, Muhammad Faheem Asim, Helmut Schmidhammer, Gerhard Wolber, Mariana Spetea

المصدر: Current Pharmaceutical Design. 19:7362-7372

مصطلحات موضوعية: Pharmacology, Virtual screening, medicine.drug_class, business.industry, Antagonist, Dynorphin, Partial agonist, Anxiolytic, Opioid receptor, Drug Discovery, medicine, Pharmacophore, business, Neuroscience, Endogenous opioid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43d20c517a4f54dea1dd31d6d731ac5f
https://doi.org/10.2174/138161281942140105162601