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1Academic Journal
المصدر: Clinical and Translational Science, Vol 17, Iss 3, Pp n/a-n/a (2024)
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Yuri Kosinsky, Simon J. Dovedi, Kirill Peskov, Veronika Voronova, Lulu Chu, Helen Tomkinson, Nidal Al-Huniti, Donald R. Stanski, Gabriel Helmlinger
المصدر: Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-15 (2018)
مصطلحات موضوعية: Radiation therapy, Immuno-oncology (IO), Checkpoint inhibitors, PD-1, PD-L1, Quantitative systems pharmacology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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المؤلفون: Rhys D.O. Jones, Klas Petersson, Areya Tabatabai, Larry Bao, Helen Tomkinson, Alwin G. Schuller
المصدر: Molecular Cancer Therapeutics. 22:679-690
مصطلحات موضوعية: Cancer Research, Oncology
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4Academic Journal
المؤلفون: Carlos Traynor, Tarjinder Sahota, Helen Tomkinson, Ignacio Gonzalez-Garcia, Neil Evans, Michael Chappell
المصدر: Journal of Personalized Medicine; Volume 11; Issue 12; Pages: 1356
مصطلحات موضوعية: imputation, real-world evidence, survival, simulation, machine-learning, statistical inference
وصف الملف: application/pdf
Relation: Epidemiology; https://dx.doi.org/10.3390/jpm11121356
الاتاحة: https://doi.org/10.3390/jpm11121356
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المؤلفون: Shringi Sharma, Xavier Pepin, Jean Cheung, Lianqing Zheng, Hua Wei, Danielle Townsley, David Han, Michal Majewski, Joseph A. Ware, James Mann, Veerendra Munugalavadla, Louise Sheridan, Priti Patel, Ashok Gupta, Helen Tomkinson
المصدر: British Journal of Clinical Pharmacology. 88:4573-4584
مصطلحات موضوعية: Adult, Pharmacology, Cross-Over Studies, Suspensions, Critical Illness, Pyrazines, Benzamides, Biological Availability, Humans, Proton Pump Inhibitors, Pharmacology (medical), Healthy Volunteers
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المؤلفون: Zhongqing He, Shringi Sharma, Joseph Ware, Helena Edlund, Helen Wei, Núria Buil-Bruna, Marshall Baek, Helen Tomkinson, Karthick Vishwanathan, Miné de Kock, Rakesh K. Raman, Huan Liu, Priti Patel
المصدر: British Journal of Clinical Pharmacology. 88:2284-2296
مصطلحات موضوعية: medicine.medical_specialty, Population, Cmax, Gastroenterology, chemistry.chemical_compound, Pharmacokinetics, Obinutuzumab, Internal medicine, medicine, Humans, Pharmacology (medical), Dosing, Adverse effect, education, Protein Kinase Inhibitors, Active metabolite, Pharmacology, education.field_of_study, business.industry, Incidence (epidemiology), Leukemia, Lymphocytic, Chronic, B-Cell, Progression-Free Survival, chemistry, Pyrazines, Benzamides, business
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11
المؤلفون: Martin Wild, Li Zhou, Tomoko Freshwater, Lokesh Jain, Helen Tomkinson, Karthick Vishwanathan, Diansong Zhou, Sherrie Xu, Sarit Cohen-Rabbie, Stein Schalkwijk
المصدر: The Journal of Clinical Pharmacology. 61:1493-1504
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Adolescent, Body Surface Area, Metabolic Clearance Rate, Itraconazole, Pharmacology, Pharmacokinetics, In vivo, Cytochrome P-450 Enzyme Inhibitors, Humans, Medicine, Drug Dosage Calculations, Drug Interactions, Pharmacology (medical), Dosing, Child, Fluconazole, Protein Kinase Inhibitors, Cytochrome P-450 Enzyme Inducers, Mitogen-Activated Protein Kinase Kinases, business.industry, MEK inhibitor, Age Factors, Clinical trial, Area Under Curve, Child, Preschool, Selumetinib, Benzimidazoles, Rifampin, business, medicine.drug
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12
المؤلفون: Sarit Cohen-Rabbie, Diansong Zhou, Stein Schalkwijk, Ioanna Gioni, Karthick Vishwanathan, Li Zhou, Karen So, Zhongqing He, Helen Tomkinson, Tomoko Freshwater, Lokesh Jain
المصدر: Cancer Chemotherapy and Pharmacology. 88:189-202
مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Nausea, Metabolite, Population, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Therapeutic index, Internal medicine, medicine, Pharmacology (medical), Adverse effect, education, Pharmacology, Body surface area, education.field_of_study, business.industry, Rash, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Selumetinib, medicine.symptom, business
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13
المؤلفون: Shringi Sharma, Xavier Pepin, Harini Burri, Lianqing Zheng, Nataliya Kuptsova‐Clarkson, Anouk de Jong, Ting Yu, Holly L. MacArthur, Michal Majewski, John C. Byrd, Richard R. Furman, Joseph A. Ware, James Mann, David Ramies, Veerendra Munugalavadla, Louise Sheridan, Helen Tomkinson
المصدر: Clinical pharmacology in drug development. 11(11)
مصطلحات موضوعية: Adult, Therapeutic Equivalency, Pyrazines, Pharmaceutical Science, Humans, Biological Availability, Pharmacology (medical), Proton Pump Inhibitors, Protein Kinase Inhibitors, Tablets
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المؤلفون: Darrell R. Abernethy, Balaji Agoram, John M. Allen, Mark E. Arnold, Arthur J. Atkinson, Thomas J. Bateman, Kimberly Bergman, Brian Booth, David W. Boulton, Robert A. Branch, Gilbert J. Burckart, Mary Buschmann, Owen Carmichael, Christine Chamberlain, Ligong Chen, Charles E. Daniels, Promi Das, Jana G. Delfino, John N. Van Den Anker, Albert W. Dreisbach, Michael Dyszel, Justin C. Earp, M. Khair ElZarrad, Osatohanmwen J. Enogieru, Elimika Pfuma Fletcher, David M. Foster, Marilynn C. Frederiksen, Aleksandra Galetin, Pamela D. Garzone, Kathleen M. Giacomini, Megan A. Gibbs, Jack A Gilbert, Danijela Gnjidic, Charles T. Gombar, Denis M. Grant, Charles Grudzinskas, Bengt Hamren, Nicholas H.G. Holford, Shiew-Mei Huang, Renee Iacona, Nina Isoherranen, Denise Jin, Bridgette L. Jones, Gregory L. Kearns, Cindy Kortepeter, Elizabeth Kunkoski, S.W. Johnny Lau, Christopher Leptak, Juan J.L. Lertora, Lawrence J. Lesko, Jiang Liu, Qi Liu, Rajanikanth Madabushi, Raymond Miller, Diane R. Mould, Monica Muñoz, Thomas D. Nolin, Robert Joseph Noveck, R. Scott Obach, Michael Pacanowski, Mary F. Paine, Carl C. Peck, Anuradha Ramamoorthy, A. David Rodrigues, Malcolm Rowland, Chandrahas G. Sahajwalla, Martina Dagmar Sahre, Robert N. Schuck, Khushboo Sharma, Tristan Sissung, Catherine S. Stika, Chris H. Takimoto, Helen Tomkinson, Jack Uetrecht, Paolo Vicini, Karen D. Vo, John A. Wagner, Yaning Wang, Yow-Ming C. Wang, Peter G. Wells, Michael J. Wick, Sook Wah Yee, Ophelia Yin, Nathalie K. Zgheib, Lei Zhang, Hao Zhu
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المؤلفون: Megan A. Gibbs, Bengt Hamrén, Helen Tomkinson, Renee Iacona, David W. Boulton
مصطلحات موضوعية: Process management, Computer science, Process (engineering), SAFER, Product (category theory), Alternative treatment
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16Concentration-QT modelling in early clinical oncology settings: Simulation evaluation of performance
المؤلفون: Corina Dota, Rhianna O'Sullivan, Gael Cantet, Alienor Berges, Vincent F. S. Dubois, Guillemette E. Benoist, Stein Schalkwijk, Joanna Parkinson, Dinko Rekić, Sarit Cohen-Rabbie, Helen Tomkinson
المصدر: British journal of clinical pharmacologyREFERENCES. 88(3)
مصطلحات موضوعية: Pharmacology, Clinical Oncology, Pediatrics, medicine.medical_specialty, Dose-Response Relationship, Drug, business.industry, Pooling, Dose level, Placebo, Medical Oncology, Confidence interval, Pooling data, Electrocardiography, Long QT Syndrome, Heart Rate, Cohort, Dose escalation, Medicine, Humans, Pharmacology (medical), Computer Simulation, business
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المؤلفون: Francesco Bellanti, Núria Buil-Bruna, Helena Edlund, Karthick Vishwanathan, Shringi Sharma, Huan Liu, Joseph Ware, Helen Tomkinson
المصدر: British journal of clinical pharmacology. 88(2)
مصطلحات موضوعية: Pharmacology, education.field_of_study, business.industry, Population, Absorption (skin), Models, Biological, Healthy Volunteers, Bioavailability, medicine.anatomical_structure, Pharmacokinetics, Neoplasms, Pyrazines, Benzamides, Medicine, Humans, Pharmacology (medical), Dosing, business, education, Compartment (pharmacokinetics), B cell, Active metabolite
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المؤلفون: Alienor Berges, Sarit Cohen-Rabbie, Corina Dota, Helen Tomkinson, Joanna Parkinson, Dinko Rekić
المصدر: Journal of clinical pharmacologyReferences. 61(8)
مصطلحات موضوعية: Drug, Oncology, medicine.medical_specialty, media_common.quotation_subject, Antineoplastic Agents, Cardiac repolarization, 030226 pharmacology & pharmacy, QT interval, law.invention, Learning experience, Food and drug administration, 03 medical and health sciences, Electrocardiography, 0302 clinical medicine, law, Internal medicine, medicine, Product Surveillance, Postmarketing, Humans, Pharmacology (medical), Drug Approval, media_common, Pharmacology, Clinical pharmacology, Dose-Response Relationship, Drug, business.industry, Europe, Long QT Syndrome, Research Design, 030220 oncology & carcinogenesis, Risk assessment, business
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المؤلفون: Jianguo Li, Alienor Berges, Tsveta Milenkova, Nidal Al-Huniti, Khanh Bui, Maria Learoyd, Helen Tomkinson, Hongmei Xu, Diansong Zhou
المصدر: Clinical Pharmacology & Therapeutics. 105:1492-1500
مصطلحات موضوعية: Oncology, medicine.medical_specialty, Gastrointestinal Diseases, Drug Compounding, Population, Antineoplastic Agents, Capsules, Poly(ADP-ribose) Polymerase Inhibitors, 030226 pharmacology & pharmacy, Piperazines, Olaparib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Therapeutic index, Breast cancer, Internal medicine, medicine, Humans, Pharmacology (medical), education, Ovarian Neoplasms, Pharmacology, Clinical Trials as Topic, education.field_of_study, Dose-Response Relationship, Drug, Proportional hazards model, business.industry, Hazard ratio, Cancer, Anemia, medicine.disease, Confidence interval, Treatment Outcome, chemistry, 030220 oncology & carcinogenesis, Phthalazines, Female, business, Tablets
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المؤلفون: Martin Johnson, Haiyi Jiang, Mitsuo Higashimori, Fredrik Nyberg, Weifeng Tang, Helen Tomkinson, Yohji Itoh, Yusuke Tanigawara, Toshio Kawata
المصدر: Cancer Chemotherapy and Pharmacology. 83:849-858
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Population, Toxicology, behavioral disciplines and activities, Gastroenterology, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, Japan, Pharmacokinetics, Risk Factors, Carcinoma, Non-Small-Cell Lung, Internal medicine, Humans, Medicine, Pharmacology (medical), Prospective Studies, Lung cancer, education, Protein Kinase Inhibitors, Aged, Aged, 80 and over, Pharmacology, Volume of distribution, education.field_of_study, business.industry, Interstitial lung disease, Middle Aged, respiratory system, medicine.disease, respiratory tract diseases, body regions, 030104 developmental biology, Oncology, Case-Control Studies, 030220 oncology & carcinogenesis, Concomitant, Cohort, Female, Lung Diseases, Interstitial, business, medicine.drug
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