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1
المؤلفون: Linda Lowes, Navid Khan, Lindsay N. Alfano, Helen Eliopoulos, Nathalie Goemans, Eugenio Mercuri, Craig M. McDonald, Jerry R. Mendell, Nanshi Sha
المصدر: Journal of Neuromuscular Diseases
مصطلحات موضوعية: Research Report, Duchenne muscular dystrophy, Male, medicine.medical_specialty, BOYS, Neuromuscular disease, Adolescent, Clinical Neurology, Walk Test, Walking, Eteplirsen, dystrophin, Morpholinos, Internal medicine, loss of ambulation, END-POINTS, medicine, Humans, In patient, eteplirsen, Child, POPULATION, Retrospective Studies, Science & Technology, 6-minute walk test, biology, business.industry, Neurosciences, Exons, medicine.disease, Duchenne, Exon skipping, PREVALENCE, Natural history, Muscular Dystrophy, Duchenne, Neurology, Case-Control Studies, Ambulatory, Mutation, biology.protein, Neurology (clinical), Neurosciences & Neurology, MUSCLE DISEASE, Dystrophin, business, Life Sciences & Biomedicine, EXONDYS 51
وصف الملف: Print
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2
المؤلفون: Frederick J. Schnell, Amy Flynt, Jessie Lynch, Helen Eliopoulos, Cas Donoghue, Linda Lowes, Jerry R. Mendell, Anthony J. Milici, Emily Naughton, D. Frank, Sarah Lewis, Johannes Dworzak, Karin Lucas, Zarife Sahenk, Robert Dracker, Linda H. Cripe, Jay S. Charleston, G. David Young, Anne M. Connolly, Lindsay N. Alfano, Louise R. Rodino-Klapac
المصدر: Medicine
مصطلحات موضوعية: musculoskeletal diseases, Male, congenital, hereditary, and neonatal diseases and abnormalities, Pediatrics, medicine.medical_specialty, Long term treatment, Duchenne muscular dystrophy, MEDLINE, Observational Study, Walk Test, Walking, Eteplirsen, Severity of Illness Index, dystrophin, law.invention, Morpholinos, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Double-Blind Method, law, Severity of illness, Diseases in Twins, upper extremity, Medicine, Humans, echocardiography, In patient, 030212 general & internal medicine, Muscular dystrophy, RNA Processing, Post-Transcriptional, Child, business.industry, vital capacity, left ventricular ejection fraction, ventricular dysfunction, General Medicine, medicine.disease, 3. Good health, Muscular Dystrophy, Duchenne, Treatment Outcome, 030220 oncology & carcinogenesis, Disease Progression, business, Research Article
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3
المؤلفون: Erik K Henricson, Navid Khan, Linda Lowes, Helen Eliopoulos, Heather Gordish-Dressman, Craig M. McDonald, Lixin Han, T. Bernard Kinane, Jerry R. Mendell
المصدر: Journal of Neuromuscular Diseases
مصطلحات موضوعية: 0301 basic medicine, Male, Research Report, medicine.medical_specialty, Adolescent, Duchenne muscular dystrophy, Vital Capacity, Eteplirsen, Morpholinos, Dystrophin, 03 medical and health sciences, FEV1/FVC ratio, 0302 clinical medicine, Exondys 51, Internal medicine, Medicine, Humans, Respiratory system, Child, Clinical Trials as Topic, business.industry, Respiration, medicine.disease, Interim analysis, forced expiratory volume, 3. Good health, Muscular Dystrophy, Duchenne, 030104 developmental biology, Neurology, Ambulatory, Neurology (clinical), Non ambulatory, business, 030217 neurology & neurosurgery, Natural history study
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4
المؤلفون: Rita Tiehen, Terri L. Leahy, Vincent L. Giranda, Gary Gordon, Helen Eliopoulos, Robert A. Carr
المصدر: Clinical Cancer Research. 14:3683-3688
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Drug Industry, Disease, Poly(ADP-ribose) Polymerase Inhibitors, Models, Biological, Phase (combat), Humans, Medicine, Enzyme Inhibitors, Intensive care medicine, Clinical Trials as Topic, Clinical Trials, Phase I as Topic, business.industry, Mechanism (biology), Drug discovery, Clinical study design, Perspective (graphical), Clinical trial, Oncology, Drug development, Drug Design, Benzimidazoles, business, DNA Damage
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5
المؤلفون: Lee J. Helman, Gary B. Gordon, Seth M. Steinberg, James H. Doroshow, Shivaani Kummar, Jerry M. Collins, Larry Rubinstein, Anne Monks, Robert J. Kinders, Helen Eliopoulos, Robert H. Wiltrout, Jennifer A. Low, Anthony J. Murgo, Lawrence R. Phillips, Martin Gutierrez, Joseph E. Tomaszewski, Ralph E. Parchment, Vincent L. Giranda, Jiuping Ji, Alice P. Chen
المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(16)
مصطلحات موضوعية: Oncology, Male, Cancer Research, medicine.medical_specialty, Pathology, Veliparib, Biopsy, Administration, Oral, Biological Availability, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Peripheral blood mononuclear cell, Poly (ADP-Ribose) Polymerase Inhibitor, chemistry.chemical_compound, Pharmacokinetics, Internal medicine, Neoplasms, Original Reports, Clinical endpoint, medicine, Humans, Enzyme Inhibitors, Aged, Clinical Trials, Phase I as Topic, Dose-Response Relationship, Drug, business.industry, Investigational New Drug, Middle Aged, Clinical trial, Treatment Outcome, chemistry, Research Design, Pharmacodynamics, Leukocytes, Mononuclear, Feasibility Studies, Benzimidazoles, Female, business
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6
المؤلفون: Anne E. Hagey, Ann M. Mauer, Moacyr Ribeiro de Oliveira, Andrew Coates, Xiangdong Zhou, Charles M. Rudin, Helen Eliopoulos, Hao Xiong
المصدر: Journal of Thoracic Oncology. 2(8)
مصطلحات موضوعية: Oncology, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Pemetrexed, business.industry, Internal medicine, Medicine, non-small cell lung cancer (NSCLC), business, medicine.disease, medicine.drug
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7
المؤلفون: Hao Xiong, Nashat Gabrail, Xiangdong Zhou, Helen Eliopoulos, Andrew Coates, Anne E. Hagey
المصدر: Journal of Thoracic Oncology. 2:S672
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Oncology, medicine.medical_specialty, Docetaxel, business.industry, Internal medicine, medicine, Non small cell, business, Lung cancer, medicine.disease, medicine.drug
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8Report
المساهمون: Helen Eliopoulos, MD, Global Project Head
المصدر: A Phase 1/2 Study Evaluating the Safety and Efficacy of ABT-751 in Combination With Docetaxel Versus Docetaxel Alone in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer