المؤلفون: Nuotio, Krista, Koskinen, Suvi M., Mäkitie, Laura, Tuimala, Jarno, Ijäs, Petra, Heikkilä, Hanna M., Saksi, Jani, Vikatmaa, Pirkka, Sorto, Pia, Kasari, Sonja, Paakkari, Ilari, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko I., Soinne, Lauri, Kovanen, Petri T., Lindsberg, Perttu J.

المساهمون: HUS Neurocenter, Research Programs Unit, Perttu Lindsberg / Principal Investigator, Clinicum, Neurologian yksikkö, HUS Medical Imaging Center, Department of Diagnostics and Therapeutics, Department of Neurosciences, Department of Pathology, University of Helsinki, HUS Abdominal Center, Verisuonikirurgian yksikkö, Medicum, Department of Pharmacology, Faculty of Medicine, Helsinki University Hospital Area, HUSLAB

مصطلحات موضوعية: carotid artery, warfarin, computed tomography angiography, histology, vascular calcification, calcification, VITAMIN-K ANTAGONIST, CORONARY, ATHEROSCLEROSIS, RISK, MICROCALCIFICATIONS, MECHANISMS, GUIDELINES, MANAGEMENT, PATHOLOGY, Neurosciences, Neurology and psychiatry

وصف الملف: application/pdf

Relation: Financial support has been received from Sigrid Juselius Foundation (PL), Helsinki University. Hospital research funds (EVO) (PL), Jane and Aatos Erkko Foundation (PL), Signe and Ane Gyllenberg Foundation (PL), Maire Taponen Foundation (HH, SMK, KN, and JS), Finnish Neuroradiological Society (SMK), Waldemar von Frenckell Foundation (SMK), The Paulo Foundation (PI), Finnish Foundation for Cardiovascular Research (HH and JS), and the Finnish Medical Foundation (KN and MM). Wihuri Research Institute is maintained by the Jenny and Antti Wihuri Foundation.; Nuotio , K , Koskinen , S M , Mäkitie , L , Tuimala , J , Ijäs , P , Heikkilä , H M , Saksi , J , Vikatmaa , P , Sorto , P , Kasari , S , Paakkari , I , Silvennoinen , H , Valanne , L , Mäyränpää , M I , Soinne , L , Kovanen , P T & Lindsberg , P J 2021 , ' Warfarin Treatment Is Associated to Increased Internal Carotid Artery Calcification ' , Frontiers in neurology , vol. 12 , 696244 . https://doi.org/10.3389/fneur.2021.696244; ORCID: /0000-0001-7690-811X/work/100023800; ORCID: /0000-0003-4588-050X/work/100024052; ORCID: /0000-0002-7292-1971/work/100024921; ORCID: /0000-0002-0877-9640/work/100024962; http://hdl.handle.net/10138/334374; 50aff02d-f2b9-488d-b926-8e362b2933c2; 000679401900001

الاتاحة: http://hdl.handle.net/10138/334374

المؤلفون: Eriksson, Henrietta E, Koskinen, Suvi, Nuotio, Krista, Heikkilä, Hanna M., Vikatmaa, Pirkka, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko, Kovanen, Petri T., Soinne, Lauri, Lindsberg, Perttu J., Ijäs, Petra

المساهمون: HUS Neurocenter, Neurologian yksikkö, Clinicum, HUS Medical Imaging Center, Department of Neurosciences, HUS Abdominal Center, Verisuonikirurgian yksikkö, Department of Diagnostics and Therapeutics, HUSLAB, Department of Pathology

مصطلحات موضوعية: Surgery, anesthesiology, intensive care, radiology, Carotid endarterectomy, Carotid stenosis, Recurrent event

وصف الملف: application/pdf

Relation: Eriksson , H E , Koskinen , S , Nuotio , K , Heikkilä , H M , Vikatmaa , P , Silvennoinen , H , Valanne , L , Mäyränpää , M , Kovanen , P T , Soinne , L , Lindsberg , P J & Ijäs , P 2020 , ' Predictive Factors for Pre-operative Recurrence of Cerebrovascular Symptoms in Symptomatic Carotid Stenosis ' , European Journal of Vascular and Endovascular Surgery , vol. 60 , no. 6 , pp. 809-815 . https://doi.org/10.1016/j.ejvs.2020.08.044; ORCID: /0000-0001-7690-811X/work/87349083; ORCID: /0000-0003-4588-050X/work/87349975; ORCID: /0000-0002-7292-1971/work/87352738; ORCID: /0000-0002-0877-9640/work/87352899; http://hdl.handle.net/10138/337417; cdddf399-54f9-42f5-a9f8-c90dbf52e053; 000599373900004

الاتاحة: http://hdl.handle.net/10138/337417

المؤلفون: Lehti, Satu, Nguyen, Su D., Belevich, Ilya, Vihinen, Helena, Heikkilä, Hanna M., Soliymani, Rabah, Käkelä, Reijo, Saksi, Jani, Jauhiainen, Matti, Grabowski, Gregory A., Kummu, Outi, Hörkkö, Sohvi, Baumann, Marc, Lindsberg, Perttu J., Jokitalo, Eija, Kovanen, Petri T., Öörni, Katariina

المساهمون: Electron Microscopy, Institute of Biotechnology, Research Programme for Molecular Neurology, Perttu Lindsberg / Principal Investigator, Research Programs Unit, Medicum, Department of Biochemistry and Developmental Biology, Biosciences, Functional Lipidomics Group, Physiology and Neuroscience (-2020), Marc Baumann / Principal Investigator, Clinicum, Department of Neurosciences, Neurologian yksikkö, HUS Neurocenter

مصطلحات موضوعية: LOW-DENSITY-LIPOPROTEIN, HUMAN ATHEROSCLEROTIC LESIONS, NLRP3 INFLAMMASOME ACTIVATION, FOAM CELL-FORMATION, SECRETORY SPHINGOMYELINASE, CHOLESTEROL CRYSTALS, PROTEOGLYCAN-BINDING, ELECTRON-MICROSCOPY, HUMAN MONOCYTES, DEFICIENT MICE, Biomedicine

وصف الملف: application/pdf

Relation: Supported by the Academy of Finland grant 265940 (K.O.), the Finnish Foundation for Cardiovascular Research (S.L. and K.O.), Helsinki University Hospital research funds [Erityisvaltionosuus (EVO)] (H.M.H., J.S., and P.J.L.), and Biocenter Finland (I.B., H.V., and E.J.). The Wihuri Research Institute is maintained by the Jenny and Antti Wihuri Foundation.; Lehti , S , Nguyen , S D , Belevich , I , Vihinen , H , Heikkilä , H M , Soliymani , R , Käkelä , R , Saksi , J , Jauhiainen , M , Grabowski , G A , Kummu , O , Hörkkö , S , Baumann , M , Lindsberg , P J , Jokitalo , E , Kovanen , P T & Öörni , K 2018 , ' Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties ' , The American Journal of Pathology , vol. 188 , no. 2 , pp. 525-538 . https://doi.org/10.1016/j.ajpath.2017.09.019; ORCID: /0000-0003-3862-9237/work/42596018; ORCID: /0000-0002-4159-6934/work/42596054; ORCID: /0000-0002-9525-0250/work/42597065; ORCID: /0000-0001-7690-811X/work/57544721; ORCID: /0000-0003-2190-4909/work/67131504; http://hdl.handle.net/10138/311770; 2e46a592-8bde-45ce-8903-133b6bc0d24b; 85044605874; 000423256300023

الاتاحة: http://hdl.handle.net/10138/311770

المؤلفون: Nuotio, Krista, Ijäs, Petra, Heikkilä, Hanna M., Koskinen, Suvi M., Saksi, Jani, Vikatmaa, Pirkka, Sorto, Pia, Mäkitie, Laura, Eriksson, Henrietta, Kasari, Sonja, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko I., Kovanen, Petri T., Soinne, Lauri, Lindsberg, Perttu J.

المساهمون: Research Programs Unit, Perttu Lindsberg / Principal Investigator, Research Programme for Molecular Neurology, University of Helsinki, Department of Neurosciences, Neurologian yksikkö, HUS Neurocenter, Clinicum, Department of Diagnostics and Therapeutics, HUS Medical Imaging Center, Verisuonikirurgian yksikkö, HUS Abdominal Center, HUSLAB, Department of Pathology, Medicum

مصطلحات موضوعية: Atherosclerosis, carotid endarterectomy, carotid stenosis, stroke, VULNERABLE PLAQUE, OCCLUSIVE DISEASE, ISCHEMIC-STROKE, ARTERY-DISEASE, EXPRESSION, CORONARY, RISK, STENOSIS, PATIENT, PROTEIN, Neurosciences, Neurology and psychiatry, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: The study was supported by the grants from Academy of Finland, Paavo Nurmi Foundation, the Paulo Foundation, Paivikki and Sakari Sohlberg Foundation, Jane and Aatos Erkko foundation, Helsinki University Hospital District governmental research funds and the Finnish Medical Foundation. Wihuri Research Institute is maintained by the Jenny and Antti Wihuri Foundation.; Nuotio , K , Ijäs , P , Heikkilä , H M , Koskinen , S M , Saksi , J , Vikatmaa , P , Sorto , P , Mäkitie , L , Eriksson , H , Kasari , S , Silvennoinen , H , Valanne , L , Mäyränpää , M I , Kovanen , P T , Soinne , L & Lindsberg , P J 2018 , ' Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques - Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2) ' , Annals of Medicine , vol. 50 , no. 6 , pp. 501-510 . https://doi.org/10.1080/07853890.2018.1494851; ORCID: /0000-0002-7292-1971/work/54792019; ORCID: /0000-0002-0877-9640/work/54792053; ORCID: /0000-0001-7690-811X/work/57544784; ORCID: /0000-0003-4588-050X/work/81357811; http://hdl.handle.net/10138/299790; aab1a75a-5631-4a5c-98f5-d1374b9e9333; 85054398550; 000458287100005

الاتاحة: http://hdl.handle.net/10138/299790

المؤلفون: Nuotio, Krista, Ijäs, Petra, Heikkilä, Hanna M., Koskinen, Suvi M., Saksi, Jani, Vikatmaa, Pirkka, Sorto, Pia, Mäkitie, Laura, Eriksson, Henrietta, Kasari, Sonja, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko I., Kovanen, Petri T., Soinne, Lauri, Lindsberg, Perttu J.

المساهمون: Paavo Nurmi Foundation, Paulo Foundation, Päivikki and Sakari Sohlberg Foundation, Jane and Aatos Erkko foundation, Helsinki University Hospital, Jenny and Antti Wihuri Foundation

المصدر: Annals of Medicine ; volume 50, issue 6, page 501-510 ; ISSN 0785-3890 1365-2060

الاتاحة: http://dx.doi.org/10.1080/07853890.2018.1494851
https://www.tandfonline.com/doi/pdf/10.1080/07853890.2018.1494851

المؤلفون: Lehti, Satu, Nguyen, Su D., Belevich, Ilya, Vihinen, Helena, Heikkilä, Hanna M., Soliymani, Rabah, Käkelä, Reijo, Saksi, Jani, Jauhiainen, Matti, Grabowski, Gregory A., Kummu, Outi, Hörkkö, Sohvi, Baumann, Marc, Lindsberg, Perttu J., Jokitalo, Eija, Kovanen, Petri T., Öörni, Katariina

المساهمون: Academy of Finland, Finnish Foundation for Cardiovascular Research

المصدر: The American Journal of Pathology ; volume 188, issue 2, page 525-538 ; ISSN 0002-9440

الاتاحة: http://dx.doi.org/10.1016/j.ajpath.2017.09.019
https://api.elsevier.com/content/article/PII:S0002944017304054?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0002944017304054?httpAccept=text/plain

المؤلفون: Nurmi, Laura, Heikkilä, Hanna M., Vapaatalo, Heikki, Kovanen, Petri T., Lindstedt, Ken A.

المصدر: Journal of Vascular Research ; volume 49, issue 1, page 13-23 ; ISSN 1018-1172 1423-0135

الاتاحة: http://dx.doi.org/10.1159/000329615
https://www.karger.com/Article/Pdf/329615

المؤلفون: Mäyränpää, Mikko I., Reséndiz, Julio C., Heikkilä, Hanna M., Lindstedt, Ken A., Kovanen, Petri T.

المصدر: Endothelium ; volume 14, issue 2, page 81-87 ; ISSN 1062-3329 1029-2373

الاتاحة: http://dx.doi.org/10.1080/10623320701346783
http://www.tandfonline.com/doi/pdf/10.1080/10623320701346783

المؤلفون: Eriksson, Henrietta, Koskinen, Suvi, Nuotio, Krista, Heikkilä, Hanna M., Vikatmaa, Pirkka, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko I., Kovanen, Petri T., Soinne, Lauri, Lindsberg, Perttu J., Ijäs, Petra

المصدر: European Journal of Vascular & Endovascular Surgery; Dec2020, Vol. 60 Issue 6, p809-815, 7p

المؤلفون: Heikkilä, Hanna M., Trosien, Julia, Metso, Jari, Jauhiainen, Matti, Pentikäinen, Markku O., Kovanen, Petri T., Lindstedt, Ken A.

المصدر: Journal of Cellular Biochemistry ; volume 109, issue 3, page 615-623 ; ISSN 0730-2312 1097-4644

الاتاحة: http://dx.doi.org/10.1002/jcb.22443
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjcb.22443
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcb.22443

المؤلفون: Heikkilä, Hanna M., Trosien, Julia, Metso, Jari, Jauhiainen, Matti, Pentikäinen, Markku O., Kovanen, Petri T., Lindstedt, Ken A.

المصدر: Journal of Cellular Biochemistry; Feb2010, Vol. 109 Issue 3, p615-623, 9p

المؤلفون: Mäyränpää MI, Heikkilä HM, Lindstedt KA, Walls AF, Kovanen PT, Mäyränpää, Mikko I, Heikkilä, Hanna M, Lindstedt, Ken A, Walls, Andrew F, Kovanen, Petri T

المصدر: Coronary Artery Disease; Nov2006, Vol. 17 Issue 7, p611-621, 11p

المؤلفون: Leskinen, Markus J.¹, Heikkilä, Hanna M.¹, Speer, Mei Y.², Hakala, Jukka K.¹, Laine, Mika³, Kovanen, Petri T.¹, Lindstedt, Ken A.¹ ken.lindstedt@wri.fi

المصدر: Experimental Cell Research. May2006, Vol. 312 Issue 8, p1289-1298. 10p.

مصطلحات موضوعية: *APOPTOSIS, *MAST cells, *VASCULAR smooth muscle, *FIBRONECTINS, *CELL death, *CELL adhesion, *ATHEROSCLEROTIC plaque

المؤلفون: Nuotio, Krista, Ijäs, Petra, Heikkilä, Hanna M., Koskinen, Suvi M., Saksi, Jani, Pirkka Vikatmaa, Sorto, Pia, Mäkitie, Laura, Eriksson, Henrietta, Kasari, Sonja, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko I., Kovanen, Petri T., Soinne, Lauri, Lindsberg, Perttu J.

مصطلحات موضوعية: 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::76e04fab7fdfff4600ba30c6c0042c51

المؤلفون: Nuotio, Krista, Ijäs, Petra, Heikkilä, Hanna M., Koskinen, Suvi M., Saksi, Jani, Pirkka Vikatmaa, Sorto, Pia, Mäkitie, Laura, Eriksson, Henrietta, Kasari, Sonja, Silvennoinen, Heli, Valanne, Leena, Mäyränpää, Mikko I., Kovanen, Petri T., Soinne, Lauri, Lindsberg, Perttu J.

مصطلحات موضوعية: 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c337f9411dec83af0850cf9545b057f7