المؤلفون: Hefzi, Hooman, Martínez-Monge, Iván, Marin de Mas, Igor, Cowie, Nicholas Luke, Toledo, Alejandro Gomez, Noh, Soo Min, Karottki, Karen Julie la Cour, Decker, Marianne, Arnsdorf, Johnny, Camacho-Zaragoza, Jose Manuel, Kol, Stefan, Schoffelen, Sanne, Pristovšek, Nuša, Hansen, Anders Holmgaard, Miguez, Antonio A, Bjorn, Sara Petersen, Brøndum, Karen Kathrine, Javidi, Elham Maria, Jensen, Kristian Lund, Stangl, Laura, Kreidl, Emanuel, Kallehauge, Thomas Beuchert, Ley, Daniel, Ménard, Patrice, Petersen, Helle Munck, Sukhova, Zulfiya, Bauer, Anton, Casanova, Emilio, Barron, Niall, Malmström, Johan, Nielsen, Lars K, Lee, Gyun Min, Kildegaard, Helene Faustrup, Voldborg, Bjørn G, Lewis, Nathan E

المصدر: bioRxiv : the preprint server for biology.

مصطلحات موضوعية: Medicin och hälsovetenskap, Medicinsk bioteknologi, Medical and Health Sciences, Medical Biotechnology, Naturvetenskap, Biologi, Cellbiologi, Natural Sciences, Biological Sciences, Cell Biology

URL الوصول: https://lup.lub.lu.se/record/99a0cba8-e91e-4a78-875d-80446a90e6ea
http://dx.doi.org/10.1101/2024.08.02.606284

المؤلفون: Masson, Helen, Karottki, Karen, Tat, Jasmine, Hefzi, Hooman, Lewis, Nathan

المصدر: Trends in Biotechnology. 41(9)

مصطلحات موضوعية: biopharmaceutical protein production, bioprocess optimization, cell line development, mechanistic models, omics, statistical inference, Animals, Biological Products, Biotechnology, Cell Line, Systems Biology, Mammals

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/14w7r8wc
https://escholarship.org/content/qt14w7r8wc/qt14w7r8wc.pdf

المؤلفون: Spahn, Philipp, Zhang, Xiaolin, Hu, Qing, Lu, Huiming, Hamaker, Nathaniel, Hefzi, Hooman, Li, Shangzhong, Kuo, Chih-Chung, Huang, Yingxiang, Lee, Jamie, Davis, Anthony, Ly, Peter, Lee, Kelvin, Lewis, Nathan

المصدر: Biotechnology and Bioengineering. 119(3)

مصطلحات موضوعية: CHO, DNA repair, cell line instability, protein expression, Animals, CHO Cells, Cricetinae, Cricetulus, DNA Repair, Genomic Instability, Karyotyping

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2t3259rv

المؤلفون: Xiong, Kai, Karottki, Karen, Hefzi, Hooman, Li, Songyuan, Grav, Lise, Li, Shangzhong, Spahn, Philipp, Lee, Jae, Ventina, Ildze, Lee, Gyun, Lewis, Nathan, Kildegaard, Helene, Pedersen, Lasse

المصدر: Cell Reports Methods. 1(7)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/50w5w52w
https://escholarship.org/content/qt50w5w52w/qt50w5w52w.pdf

المؤلفون: Shamie, Isaac, Duttke, Sascha H, Karottki, Karen J la Cour, Han, Claudia Z, Hansen, Anders H, Hefzi, Hooman, Xiong, Kai, Li, Shangzhong, Roth, Samuel J, Tao, Jenhan, Lee, Gyun Min, Glass, Christopher K, Kildegaard, Helene Faustrup, Benner, Christopher, Lewis, Nathan E

المصدر: NAR genomics and bioinformatics. 3(3)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6cn1b1j4

المؤلفون: Xiong, Kai, la Cour Karottki, Karen Julie, Hefzi, Hooman, Li, Songyuan, Grav, Lise Marie, Li, Shangzhong, Spahn, Philipp, Lee, Jae Seong, Ventina, Ildze, Lee, Gyun Min, Lewis, Nathan E, Kildegaard, Helene Faustrup, Pedersen, Lasse Ebdrup

المصدر: Cell Reports Methods. 1(4)

مصطلحات موضوعية: Biotechnology, Genetics, Human Genome, Aetiology, 2.2 Factors relating to the physical environment

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1b08k7xg
https://escholarship.org/content/qt1b08k7xg/qt1b08k7xg.pdf

المؤلفون: Karottki, Karen Julie la Cour, Hefzi, Hooman, Li, Songyuan, Pedersen, Lasse Ebdrup, Spahn, Philipp N, Joshi, Chintan, Ruckerbauer, David, Bort, Juan A Hernandez, Thomas, Alex, Lee, Jae Seong, Borth, Nicole, Lee, Gyun Min, Kildegaard, Helene Faustrup, Lewis, Nathan E

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Industrial Biotechnology, Biotechnology, Genetics, Underpinning research, 1.1 Normal biological development and functioning, Animals, CHO Cells, CRISPR-Cas Systems, Cricetinae, Cricetulus, Gene Editing, Glutamine, CHO, CRISPR pooled Screen, Metabolism, Biochemistry and cell biology, Industrial biotechnology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1cz095kj

المؤلفون: Hefzi, Hooman, Martínez-Monge, Iván, Marin de Mas, Igor, Cowie, Nicholas Luke, Toledo, Alejandro Gomez, Noh, Soo Min, Karottki, Karen Julie la Cour, Decker, Marianne, Arnsdorf, Johnny, Camacho-Zaragoza, Jose Manuel, Kol, Stefan, Schoffelen, Sanne, Pristovšek, Nuša, Hansen, Anders Holmgaard, Miguez, Antonio A, Bjørn, Sara Petersen, Brøndum, Karen Kathrine, Javidi, Elham Maria, Jensen, Kristian Lund, Stangl, Laura, Kreidl, Emanuel, Kallehauge, Thomas Beuchert, Ley, Daniel, Ménard, Patrice, Petersen, Helle Munck, Sukhova, Zulfiya, Bauer, Anton, Casanova, Emilio, Barron, Niall, Malmström, Johan, Nielsen, Lars K, Lee, Gyun Min, Kildegaard, Helene Faustrup, Voldborg, Bjørn G, Lewis, Nathan E

المصدر: Nature Metabolism; (2025) ; ISSN: 2522-5812

مصطلحات موضوعية: Cell and Molecular Biology

Relation: pmid:39809975

الاتاحة: https://lup.lub.lu.se/record/562157c4-62ed-485d-875a-c889657ac06d
https://doi.org/10.1038/s42255-024-01193-7

المؤلفون: la Cour Karottki, Karen Julie, Hefzi, Hooman, Xiong, Kai, Shamie, Isaac, Hansen, Anders Holmgaard, Li, Songyuan, Pedersen, Lasse Ebdrup, Li, Shangzhong, Lee, Jae Seong, Lee, Gyun Min, Kildegaard, Helene Faustrup, Lewis, Nathan E

المصدر: Biotechnology and Bioengineering. 117(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Animals, CHO Cells, CRISPR-Cas Systems, Cricetinae, Cricetulus, Gene Editing, Glycosylation, Glycosyltransferases, Phenotype, Polysaccharides, CHO, CRISPRa, glycosylation, Mgat3, St6gal1, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9cc5b55t

المؤلفون: Gutierrez, Jahir M, Feizi, Amir, Li, Shangzhong, Kallehauge, Thomas B, Hefzi, Hooman, Grav, Lise M, Ley, Daniel, Baycin Hizal, Deniz, Betenbaugh, Michael J, Voldborg, Bjorn, Faustrup Kildegaard, Helene, Min Lee, Gyun, Palsson, Bernhard O, Nielsen, Jens, Lewis, Nathan E

المصدر: Nature communications. 11(1)

مصطلحات موضوعية: CHO Cells, Animals, Mammals, Humans, Cricetulus, Mice, Proteins, Recombinant Proteins, Reproducibility of Results, Genome, Computer Simulation, Bone Morphogenetic Protein 2, Secretory Pathway, Gene Knockdown Techniques, Vaccine Related, Prevention, Biodefense, Biotechnology, 1.1 Normal biological development and functioning, Generic health relevance

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6x51w8qm

المؤلفون: Brunk, Elizabeth, Chang, Roger L, Xia, Jing, Hefzi, Hooman, Yurkovich, James T, Kim, Donghyuk, Buckmiller, Evan, Wang, Harris H, Cho, Byung-Kwan, Yang, Chen, Palsson, Bernhard O, Church, George M, Lewis, Nathan E

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(43)

مصطلحات موضوعية: Biotechnology, Human Genome, Genetics, Escherichia coli, Gene Editing, Metabolic Engineering, Prokaryotic Cells, Protein Processing, Post-Translational, Proteins, Workflow, systems biology, posttranslational modifications, metabolism, protein chemistry, omics data

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3hf078gb

المؤلفون: Abdel-Haleem, Alyaa M, Hefzi, Hooman, Mineta, Katsuhiko, Gao, Xin, Gojobori, Takashi, Palsson, Bernhard O, Lewis, Nathan E, Jamshidi, Neema

المصدر: PLoS computational biology. 14(1)

مصطلحات موضوعية: Animals, Humans, Culicidae, Plasmodium falciparum, Malaria, Disease Models, Animal, Choline, Pantothenic Acid, Thiamine, Systems Biology, Species Specificity, Gene Expression Regulation, Gene Deletion, Glycolysis, Life Cycle Stages, Genome, Models, Biological, Food, Vector-Borne Diseases, Rare Diseases, Nutrition, Infectious Diseases, Orphan Drug, 2.2 Factors relating to the physical environment, Infection, Bioinformatics, Mathematical Sciences, Biological Sciences, Information and Computing Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6st0z46t

المؤلفون: Hefzi, Hooman, Ang, Kok Siong, Hanscho, Michael, Bordbar, Aarash, Ruckerbauer, David, Lakshmanan, Meiyappan, Orellana, Camila A, Baycin-Hizal, Deniz, Huang, Yingxiang, Ley, Daniel, Martinez, Veronica S, Kyriakopoulos, Sarantos, Jiménez, Natalia E, Zielinski, Daniel C, Quek, Lake-Ee, Wulff, Tune, Arnsdorf, Johnny, Li, Shangzhong, Lee, Jae Seong, Paglia, Giuseppe, Loira, Nicolas, Spahn, Philipp N, Pedersen, Lasse E, Gutierrez, Jahir M, King, Zachary A, Lund, Anne Mathilde, Nagarajan, Harish, Thomas, Alex, Abdel-Haleem, Alyaa M, Zanghellini, Juergen, Kildegaard, Helene F, Voldborg, Bjørn G, Gerdtzen, Ziomara P, Betenbaugh, Michael J, Palsson, Bernhard O, Andersen, Mikael R, Nielsen, Lars K, Borth, Nicole, Lee, Dong-Yup, Lewis, Nathan E

المصدر: Cell Systems. 3(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Industrial Biotechnology, Bioengineering, Animals, CHO Cells, Consensus, Cricetinae, Cricetulus, Genome, Humans, Metabolic Networks and Pathways, Recombinant Proteins, CHO, Chinese hamster ovary, biotherapeutic protein production, genome-scale model, metabolic network, systems biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2pv1t5k4

المؤلفون: Swainston, Neil, Smallbone, Kieran, Hefzi, Hooman, Dobson, Paul D, Brewer, Judy, Hanscho, Michael, Zielinski, Daniel C, Ang, Kok Siong, Gardiner, Natalie J, Gutierrez, Jahir M, Kyriakopoulos, Sarantos, Lakshmanan, Meiyappan, Li, Shangzhong, Liu, Joanne K, Martínez, Veronica S, Orellana, Camila A, Quek, Lake-Ee, Thomas, Alex, Zanghellini, Juergen, Borth, Nicole, Lee, Dong-Yup, Nielsen, Lars K, Kell, Douglas B, Lewis, Nathan E, Mendes, Pedro

المصدر: Metabolomics. 12(7)

مصطلحات موضوعية: Biotechnology, Genetics, Human Genome, Nutrition, Generic health relevance, Human, Metabolism, Modelling, Reconstruction, Model, Systems biology, Analytical Chemistry, Biochemistry and Cell Biology, Clinical Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3df064j4
https://escholarship.org/content/qt3df064j4/qt3df064j4.pdf

المؤلفون: Hefzi, Hooman

مصطلحات الفهرس: person

URL: https://orbit.dtu.dk/en/persons/1f81807f-6ff3-436d-9565-efda70a924bc

المؤلفون: Monge, Ivan Martinez, Hefzi, Hooman, Sanchez, Pere Comas, Marín de Mas, Igor Batolomé, Decker, Marianne, Lecina, Martí, Cairó, Jordi Joan, Lewis, Nathan, Nielsen, Lars Keld

المصدر: Monge , I M , Hefzi , H , Sanchez , P C , Marín de Mas , I B , Decker , M , Lecina , M , Cairó , J J , Lewis , N & Nielsen , L K 2020 , ' Lactate reduction in CHO cell cultures through metabolic analysis ' .

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/88a705b5-5f0e-40b9-b8ca-455e124be964

الاتاحة: https://orbit.dtu.dk/en/publications/88a705b5-5f0e-40b9-b8ca-455e124be964
https://backend.orbit.dtu.dk/ws/files/216677825/IMM_ESACT_2019_IG_LKN.pdf

المؤلفون: Xiong, Kai, Karottki, Karen Julie la Cour, Hefzi, Hooman, Li, Songyuan, Grav, Lise Marie, Li, Shangzhong, Spahn, Philipp, Lee, Jae Seong, Ventina, Ildze, Lee, Gyun Min, Lewis, Nathan E., Kildegaard, Helene Faustrup, Pedersen, Lasse Ebdrup

المصدر: Xiong , K , Karottki , K J L C , Hefzi , H , Li , S , Grav , L M , Li , S , Spahn , P , Lee , J S , Ventina , I , Lee , G M , Lewis , N E , Kildegaard , H F & Pedersen , L E 2021 , ' Erratum : An optimized genome-wide, virus-free CRISPR screen for mammalian cells (Cell Reports Methods (2021) 1(4), (S2667237521001107), (10.1016/j.crmeth.2021.100062)) ' , Cell Reports Methods , vol. 1 , no. 7 , 100115 . https://doi.org/10.1016/j.crmeth.2021.100115

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/4f8d38c3-f0c7-47c7-aa83-44612dc9ba97

الاتاحة: https://orbit.dtu.dk/en/publications/4f8d38c3-f0c7-47c7-aa83-44612dc9ba97
https://doi.org/10.1016/j.crmeth.2021.100115
https://backend.orbit.dtu.dk/ws/files/269917962/1_s2.0_S266723752100179X_main.pdf

المؤلفون: Julie la Cour Karottki, Karen, Hefzi, Hooman, Xiong, Kai, Shamie, Isaac, Hansen, Anders Holmgaard, Li, Songyuan, Pedersen, Lasse Ebdrup, Li, Shangzhong, Lee, Jae Seong, Min Lee, Gyun, Kildegaard, Helene Faustrup, Lewis, Nathan E.

المصدر: Julie la Cour Karottki , K , Hefzi , H , Xiong , K , Shamie , I , Hansen , A H , Li , S , Pedersen , L E , Li , S , Lee , J S , Min Lee , G , Kildegaard , H F & Lewis , N E 2020 , ' Awakening dormant glycosyltransferases in CHO cells with CRISPRa ' , Biotechnology and Bioengineering , vol. 117 , no. 2 , pp. 593-598 . https://doi.org/10.1002/bit.27199

مصطلحات موضوعية: CHO, CRISPRa, Glycosylation, Mgat3, St6gal11

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/4ff27313-8f0d-44e4-b70c-6ab07c7adec8

الاتاحة: https://orbit.dtu.dk/en/publications/4ff27313-8f0d-44e4-b70c-6ab07c7adec8
https://doi.org/10.1002/bit.27199
https://backend.orbit.dtu.dk/ws/files/203289020/melju_Karottki_et_al_2019_Biotechnology_and_Bioengineering.pdf

المؤلفون: Ley, Daniel, Pereira, Sara, Pedersen, Lasse Ebdrup, Arnsdorf, Johnny, Hefzi, Hooman, Davy, Anne Mathilde, Kwang Ha, Tae, Wulff, Tune, Kildegaard, Helene Faustrup, Andersen, Mikael Rørdam

المصدر: Ley , D , Pereira , S , Pedersen , L E , Arnsdorf , J , Hefzi , H , Davy , A M , Kwang Ha , T , Wulff , T , Kildegaard , H F & Andersen , M R 2019 , ' Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion ' , Metabolic Engineering , vol. 56 , pp. 120-129 . https://doi.org/10.1016/j.ymben.2019.09.005

مصطلحات موضوعية: Chinese hamster ovary cells, Lactate, Ammonium, AA catabolism, CRISPR, Metabolic network reconstruction

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/e6e02b2a-1da9-46ca-ab3f-71e6a95e52f8

الاتاحة: https://orbit.dtu.dk/en/publications/e6e02b2a-1da9-46ca-ab3f-71e6a95e52f8
https://doi.org/10.1016/j.ymben.2019.09.005
https://backend.orbit.dtu.dk/ws/files/219076574/1_s2.0_S1096717619301442_main.pdf

المؤلفون: Kim, Su Hyun, Shin, Seunghyeon, Baek, Minhye, Xiong, Kai, Cour Karottki, Karen Julie la, Hefzi, Hooman, Marie Grav, Lise, Ebdrup Pedersen, Lasse, Faustrup Kildegaard, Helene, Lewis, Nathan E., Lee, Jae Seong, Lee, Gyun Min

المصدر: Cell Culture Engineering XVIII

مصطلحات موضوعية: CHO cells, CRISPR screen, osmotic stress, cell engineering, therapeutic protein

Relation: https://dc.engconfintl.org/ccexviii/203; https://dc.engconfintl.org/context/ccexviii/article/1086/filename/0/type/additional/viewcontent/Poster_37.pdf

الاتاحة: https://dc.engconfintl.org/ccexviii/203
https://dc.engconfintl.org/context/ccexviii/article/1086/filename/0/type/additional/viewcontent/Poster_37.pdf