المؤلفون: Qingping Xu, Gilles P. van Wezel, Hsiu-Ju Chiu, Lukasz Jaroszewski, Heath E. Klock, Mark W. Knuth, Mitchell D. Miller, Scott A. Lesley, Adam Godzik, Marc-André Elsliger, Ashley M. Deacon, Ian A. Wilson

المصدر: PLoS ONE, Vol 7, Iss 8 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3413718; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/57d43aff9e024711b4ba64682fb8eb2c

المؤلفون: Qingping Xu, Gilles P van Wezel, Hsiu-Ju Chiu, Lukasz Jaroszewski, Heath E Klock, Mark W Knuth, Mitchell D Miller, Scott A Lesley, Adam Godzik, Marc-André Elsliger, Ashley M Deacon, Ian A Wilson

المصدر: PLoS ONE, Vol 7, Iss 7, p e41359 (2012)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3406030?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/22bb6da506f943bd8bc2e65b7fefc3c6

الاتاحة: https://doi.org/10.1371/journal.pone.0041359
https://doaj.org/article/22bb6da506f943bd8bc2e65b7fefc3c6

المؤلفون: Abhinav Kumar, Sabine Möcklinghoff, Fumiaki Yumoto, Lukasz Jaroszewski, Carol L Farr, Anna Grzechnik, Phuong Nguyen, Christian X Weichenberger, Hsiu-Ju Chiu, Heath E Klock, Marc-André Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Bruce R Conklin, Robert J Fletterick, Ian A Wilson

المصدر: PLoS ONE, Vol 7, Iss 9, p e43761 (2012)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3439487?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/ea0eeba6acc149beb88802036b6c31a7

الاتاحة: https://doi.org/10.1371/journal.pone.0043761
https://doaj.org/article/ea0eeba6acc149beb88802036b6c31a7

المؤلفون: Debanu Das, Mireille Hervé, Julie Feuerhelm, Carol L Farr, Hsiu-Ju Chiu, Marc-André Elsliger, Mark W Knuth, Heath E Klock, Mitchell D Miller, Adam Godzik, Scott A Lesley, Ashley M Deacon, Dominique Mengin-Lecreulx, Ian A Wilson

المصدر: PLoS ONE, Vol 6, Iss 3, p e17624 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3060825?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3579f29d15a044a7b200ed31f29f9110

المؤلفون: Qingping Xu, Neil D Rawlings, Hsiu-Ju Chiu, Lukasz Jaroszewski, Heath E Klock, Mark W Knuth, Mitchell D Miller, Marc-Andre Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Ian A Wilson

المصدر: PLoS ONE, Vol 6, Iss 7, p e22013 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3142127?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/8d7470ad34784f1d8219b7ac8a34f5ed

المؤلفون: Qingping Xu, Neil D Rawlings, Carol L Farr, Hsiu-Ju Chiu, Joanna C Grant, Lukasz Jaroszewski, Heath E Klock, Mark W Knuth, Mitchell D Miller, Dana Weekes, Marc-André Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Ian A Wilson

المصدر: PLoS ONE, Vol 6, Iss 7, p e21875 (2011)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3143127?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/97645952e15f40f58e65882fee83ec22

الاتاحة: https://doi.org/10.1371/journal.pone.0021875
https://doaj.org/article/97645952e15f40f58e65882fee83ec22

المؤلفون: Crystallization, Herbert L. Axelrod, B Debanu Das, Polat Abdubek, C Tamara, D Constantina Bakolitsa, Dennis Carlton, F Connie Chen, Hsiu-ju Chiu, B Thomas Clayton, Marc C. Deller, F Lian Duan, D Kyle, D Carol L. Farr, F Julie, C Joanna C. Grant, C Anna, F Gye Won Han, F Lukasz, E Kevin K. Jin, Heath E. Klock, C Mark W. Knuth, Piotr Kozbial, E S. Sri Krishna, Abhinav Kumar, B Winnie W. Lam, David Marciano, F Daniel, G Mitchell D. Miller, Andrew T. Morse, D Edward, C Am, A Nopakun, Linda Okach, C Christina Puckett, Ron Reyes, B Natasha Sefcovic, Henry J. Tien, F Christine B. Trame, Henry Van Den Bedem, B Dana, Qingping Xu, B Keith O. Hodgson, Ashley M. Deacon, B Adam, E Scott A. Lesley B, Ian A. Wilson B

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/e3/a4/Acta_Crystallogr_Sect_F_Struct_Biol_Cryst_Commun_2010_Aug_4_66(Pt_10)_1335-1346.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.352.372

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.352.372

المؤلفون: Crystallization, C Christopher L. Rife, C Polat, D Tamara Astakhova, Herbert L. Axelrod, C Dennis, F Connie Chen, D Hsiu-ju, C Marc C. Deller, F Lian Duan, Kyle Ellrott, E Carol L. Farr, F Julie, D Joanna C. Grant, D Anna, F Gye Won Han, F Lukasz, E Kevin K. Jin, Heath E. Klock, D Mark W. Knuth, Piotr Kozbial, B S. Sri Krishna, Abhinav Kumar, C Winnie W. Lam, David Marciano, F Daniel, D Mitchell D. Miller, Andrew T. Morse, E Edward, D Am, A Nopakun, Ron Reyes, C Henry J. Tien, Christine B. Trame

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ce/c6/Acta_Crystallogr_Sect_F_Struct_Biol_Cryst_Commun_2010_Sep_22_66(Pt_10)_1274-1280.tar.gz

مصطلحات موضوعية: Hodgson, g John Wooley

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.351.7140

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.351.7140

المؤلفون: Crystallization, Herbert L. Axelrod, B Piotr Kozbial, Daniel Mcmullan, D S. Sri Krishna, Mitchell D. Miller, D Polat Abdubek, Claire Acosta, D Tamara Astakhova, Dennis Carlton, F Jonathan, B Hsiu-ju Chiu, B Thomas, E Ylva Elias, F Julie, D Slawomir K, D Joanna C. Grant, Gye Won Han, F Lukasz, E Kevin K. Jin, Heath E. Klock, D Mark W. Knuth, Andrew T. Morse, E Kevin D, F Edward Nigoghossian, Linda Okach, D Silvya Oommachen, Jessica Paulsen, D Ron Reyes, Christopher L. Rife, B Henry J. Tien, Christina V. Trout, B Dana Weekes, C Aprilfawn, D Qingping Xu, B Chloe, E Marc-andré Elsliger, Ashley M. Deacon, B Adam Godzik, Scott A. Lesley A, Ian A

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/eb/7c/Acta_Crystallogr_Sect_F_Struct_Biol_Cryst_Commun_2009_Oct_27_66(Pt_10)_1347-1353.tar.gz

مصطلحات موضوعية: Zubieta, b Keith O. Hodgson, g John

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.351.7889

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.351.7889

المؤلفون: Crystallization, Mitchell D. Miller, C S. Sri Krishna, Polat Abdubek, F Tamara Astakhova, Herbert L. Axelrod, C Hsiu-ju Chiu, Thomas Clayton, D Marc C. Deller, Lian Duan, E Marc-andré Elsliger, Julie Feuerhelm, F Slawomir K, E Joanna C. Grant, Gye Won Han, D Lukasz, E Kevin K. Jin, Heath E. Klock, F Mark W. Knuth, Piotr Kozbial, B David Marciano, Daniel Mcmullan, F Andrew T, E Edward Nigoghossian, Jessica Paulsen, F Ron Reyes, Christopher L. Rife, C Henry J. Tien

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/bf/0a/Acta_Crystallogr_Sect_F_Struct_Biol_Cryst_Commun_2009_Oct_27_66(Pt_10)_1205-1210.tar.gz

مصطلحات موضوعية: Bioinformatics and Systems Biology, Burnham

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.350.8495

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.350.8495

المؤلفون: Catharine L. Eastman, Gregory B. Chisholm, Julie Vance, Kai Zinn, Dirk Siepe, Heath E. Klock, K. Christopher Garcia, Scott Martin Glaser, Scott A. Lesley, Sarah Cox, Woj M. Wojtowicz, Jost Vielmetter, Ricardo A. Fernandes, Paul Anderson, Melisa L. Bragstad, Annie W. Lam, Jessica J. Miller, Sarah Rue

المصدر: Cell

مصطلحات موضوعية: Cell type, receptor, Cell, Receptors, Cell Surface, interactome, Computational biology, Biology, Ligands, ligand, Interactome, General Biochemistry, Genetics and Molecular Biology, Article, Protein–protein interaction, 03 medical and health sciences, 0302 clinical medicine, Signaling Lymphocytic Activation Molecule Family, medicine, Humans, Protein Interaction Maps, Receptor, Phylogeny, 030304 developmental biology, 0303 health sciences, human IgSF, protein-protein interaction screen, Receptor-Like Protein Tyrosine Phosphatases, Class 2, Receptors, Interleukin-1, Surface Plasmon Resonance, DCC Receptor, medicine.anatomical_structure, Secretory protein, cell-surface, network, Immunoglobulin superfamily, 030217 neurology & neurosurgery, Function (biology)

وصف الملف: application/pdf; application/msword; application/vnd.ms-excel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb88b5e0a3459806af75a948cee0f7a
https://pubmed.ncbi.nlm.nih.gov/32822567

المؤلفون: Jonathan Yen, Vionnie W. C. Yu, Ning Guo, Susan C. Stevenson, Yi Liu, William R. Tschantz, Yi Yang, Craig Mickanin, Michael Fiorino, Scott Clarkson, Lisa Quinn, Carsten Russ, Cameron Lee, Steven Paula, Heath E. Klock

المصدر: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

مصطلحات موضوعية: 0301 basic medicine, Hematopoietic Stem And Progenitor Cells (HSPCs), Science, Biology, Transplantation, Autologous, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Genome editing, CRISPR-Associated Protein 9, Autologous transplantation, Animals, Humans, Progenitor cell, Cells, Cultured, Fetal Hemoglobin, Ribonucleoprotein, Gene Editing, Multidisciplinary, Cas9, Hematopoietic Stem Cell Transplantation, Neon Electroporation, Purified Cas9 Protein, Membranes, Artificial, Genetic Therapy, Hematopoietic Stem Cells, Syringe Connector, Cell biology, Transplantation, Hemoglobinopathies, Haematopoiesis, 030104 developmental biology, Electroporation, Ribonucleoproteins, Models, Animal, Medicine, Female, HSPC Expansion, Stem cell, CRISPR-Cas Systems, 030217 neurology & neurosurgery, Filtration, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56abc87475d1a0c7b05bd1383e1f91a2
https://pubmed.ncbi.nlm.nih.gov/30389991

المؤلفون: Loren Miraglia, S. Whitney Barnes, Jennifer Snead, Carsten Russ, Peter McNamara, John Lamb, Albert E. Parker, Chris Trussell, J. Scott Lee, Orzala Sharif, Pamela Y. Ting, John R. Walker, Michael P. Cooke, Anthony E. Boitano, Scott Clarkson, Fabio Luna, Heath E. Klock, Julie Vance, Mu-Yun Gao, Christian Schmedt, Glenn C. Federe

المصدر: Nature methods. 15(11)

مصطلحات موضوعية: 0301 basic medicine, Computer science, High-throughput screening, Computational biology, CD8-Positive T-Lymphocytes, Biochemistry, Genome, 03 medical and health sciences, Genome editing, CRISPR-Associated Protein 9, CRISPR, Humans, Guide RNA, Progenitor cell, Molecular Biology, Cells, Cultured, Gene Editing, Cas9, Genome, Human, Cell Biology, Hematopoietic Stem Cells, 030104 developmental biology, HEK293 Cells, CRISPR-Cas Systems, Functional genomics, Biotechnology, RNA, Guide, Kinetoplastida

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d6ea3f1ecc35af01d19e315b272f72
https://pubmed.ncbi.nlm.nih.gov/30297964

المؤلفون: Weijia Ou, Susan E. Cellitti, Bernhard H. Geierstanger, Paula Patterson, Xing Wang, Heath E. Klock, Edward Nigoghossian, Ansgar Brock, Hung Tong, Dylan Daniel, Jan Grünewald, Badry Bursulaya, William Mallet, David H. Jones, Tetsuo Uno, Daniel McMullan, Hsien-Po Chiu, Julie Vance, Huanfang Zhou, Scott A. Lesley

المصدر: Bioconjugate Chemistry. 26:2554-2562

مصطلحات موضوعية: Immunoconjugates, Biomedical Engineering, Mice, Nude, Transferases (Other Substituted Phosphate Groups), Pharmaceutical Science, Antineoplastic Agents, Bioengineering, medicine.disease_cause, Substrate Specificity, Serine, Mice, Residue (chemistry), Bacterial Proteins, Pharmacokinetics, Neoplasms, medicine, Animals, Humans, Aminobenzoates, Pharmacology, Oligopeptide, biology, Chemistry, Toxin, Organic Chemistry, Trastuzumab, body regions, Biochemistry, Cell culture, biology.protein, Antibody, Peptides, Oligopeptides, Biotechnology, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7286bacea55f1489eb11261e6f30abd6
https://doi.org/10.1021/acs.bioconjchem.5b00558

المؤلفون: Jan Grünewald, Weijia Ou, Huanfang Zhou, Tetsuo Uno, Xing Wang, Heath E. Klock, Eric C. Peters, Jessica Read, Ansgar Brock, Julie Vance, Jin Yunho, Yongqin Wan, Bernhard H. Geierstanger

المصدر: Bioconjugate chemistry. 28(7)

مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Stereochemistry, Coenzyme A, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Peptide, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Stability, Structure–activity relationship, Animals, Aminobenzoates, Pharmacology, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Cytotoxins, Organic Chemistry, Antibodies, Monoclonal, 0104 chemical sciences, Amino acid, 030104 developmental biology, Phosphopantetheine, Bioorthogonal chemistry, Linker, Oligopeptides, Biotechnology, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63bd99ba14848ee5878640e2a238e6d3
https://pubmed.ncbi.nlm.nih.gov/28590752

المؤلفون: Abhinav Kumar, Hsiu-Ju Chiu, Ian A. Wilson, Adam Godzik, Marc-André Elsliger, Debanu Das, Joanna C Grant, Penelope Coggill, Marco Punta, Heath E. Klock, Mitchell D. Miller, Carol L. Farr, Ashley M. Deacon, Scott A. Lesley, Herbert L. Axelrod

المصدر: Protein Science. 23:1380-1391

مصطلحات موضوعية: chemistry.chemical_classification, food and beverages, Sequence alignment, Crystal structure, Biology, biology.organism_classification, Biochemistry, Sugar binding, Amino acid, Protein structure, chemistry, Domain of unknown function, Binding site, Bacteroides, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::539e5aa26e6c6cf6fb7ef988ec77a05b
https://doi.org/10.1002/pro.2522

المؤلفون: Debanu Das, Mark W. Knuth, Heath E. Klock, Ian A. Wilson, Abhinav Kumar, Lukasz Jaroszewski, Scott A. Lesley, Adam Godzik, Ashley M. Deacon, Mitchell D. Miller, Marc-André Elsliger, Hsiu-Ju Chiu, Nicholas M. Fleischman, Qingping Xu, Michael D. Toney

المصدر: Protein Science. 23:1060-1076

مصطلحات موضوعية: chemistry.chemical_classification, Human microbiome, Biology, biology.organism_classification, Biochemistry, Cofactor, Microbiology, chemistry.chemical_compound, Enzyme, chemistry, Phosphoserine, biology.protein, Transferase, lipids (amino acids, peptides, and proteins), Eubacterium, Pyridoxal phosphate, Molecular Biology, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b901d049c13950b853bf04f2f2f60395
https://doi.org/10.1002/pro.2493

المؤلفون: Mireille Hervé, Rameshwar U. Kadam, Joanna C Grant, Ashley M. Deacon, M.A. Elsliger, Heath E. Klock, Hsiu-Ju Chiu, Adam Godzik, Debanu Das, Ian A. Wilson, Scott A. Lesley, Mitchell D. Miller, Dominique Mengin-Lecreulx, Mark W. Knuth

المصدر: Journal of bacteriology, vol 195, iss 24

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Molecular Sequence Data, Carboxypeptidases, Peptidoglycan, Crystallography, X-Ray, Medical and Health Sciences, Microbiology, Bacterial cell structure, Cell wall, chemistry.chemical_compound, Protein structure, Models, Hydrolase, Amino Acid Sequence, Molecular Biology, chemistry.chemical_classification, DNA ligase, Crystallography, Binding Sites, Agricultural and Veterinary Sciences, biology, Tetrapeptide, Molecular, Articles, Biological Sciences, Carboxypeptidase, Sphingomonadaceae, chemistry, Biochemistry, X-Ray, biology.protein, Generic health relevance, Protein Multimerization, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f459e09e5bc2def68889d8edc97eb0
https://doi.org/10.1128/jb.00900-13

المؤلفون: Joanna C Grant, Debanu Das, Stuart Kornfeld, Ian A. Wilson, Scott A. Lesley, Mitchell D. Miller, Heath E. Klock, Wang Sik Lee, Carol L. Farr, Mark W. Knuth, Ashley M. Deacon, Marc-André Elsliger, Julie Vance, Hsiu-Ju Chiu, Adam Godzik

المصدر: Journal of Biological Chemistry. 288:16789-16799

مصطلحات موضوعية: chemistry.chemical_classification, Protein family, Phosphoric Diester Hydrolases, Cell Biology, Mannose 6-phosphate, Biology, Crystallography, X-Ray, Biochemistry, Structural genomics, chemistry.chemical_compound, Enzyme, Bacterial Proteins, Structural biology, chemistry, Mutagenesis, Structural Homology, Protein, Catalytic Domain, Protein Structure and Folding, Bacteroides, Humans, Glycoside hydrolase, Glycoprotein, Molecular Biology, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a7fa3a063adacd44b6873f3efb81d2
https://doi.org/10.1074/jbc.m112.434977

المؤلفون: Jeff Velasquez, Tanya Biorac, Adam Godzik, Peter Kuhn, Raymond C. Stevens, Guenter Wolf, Jie Ouyang, Heath E. Klock, Ross Floyd, Xiaoping Dai, Andreas Kreusch, Rebecca Page, Bill West, Keith O. Hodgson, Alyssa Robb, Hsiu-Ju Chiu, Jaume M. Canaves, Xianhong Wang, Scott A. Lesley, Linda S. Brinen, Andrew T. Morse, Juli Vincent, John S. Kovarik, Timothy M. McPhillips, Kin Moy, Marc-André Elsliger, Ashley M. Deacon, Mitchell D. Miller, Robert Schwarzenbacher, Ian A. Wilson, Frank von Delft, Eileen Ambing, Glen Spraggon, Mike DiDonato, Said Eshagi, Henry van den Bedem, Eric Hampton, Jamison Cambell, Eric Koesema, Carina Grittini, Kevin Quijano, Cathy Karlak, Polat Abdubek, Daniel McMullan, Inna Levin, John Wooley, Slawomir K. Grzechnik, Lukasz Jaroszewski, Qingping Xu

مصطلحات موضوعية: Models, Molecular, biology, Protein Conformation, Chemistry, Molecular Sequence Data, Resolution (electron density), Imidazoles, Reproducibility of Results, Crystal structure, Crystallography, X-Ray, biology.organism_classification, Lyase, Biochemistry, Crystallography, Mutase, Structural Biology, Thermotoga maritima, Amino Acid Sequence, Crystallization, Intramolecular Transferases, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cce9e943b2167cf7145741512164107
https://ora.ox.ac.uk/objects/uuid:58074e2d-7158-41bb-b2ca-80766c134680