نتائج البحث - "Hashizume, Tsuneo"

1

Academic Journal

Development of a micronucleus test using the EpiAirway™ organotypic human airway model

المؤلفون: Munakata, Satoru, Watanabe, Taku, Takahashi, Tomohiro, Kimuro, Shiori, Ishimori, Kanae, Hashizume, Tsuneo

المساهمون: Japan Tobacco Inc.

المصدر: Genes and Environment ; volume 45, issue 1 ; ISSN 1880-7062

الاتاحة: http://dx.doi.org/10.1186/s41021-023-00269-2
https://link.springer.com/content/pdf/10.1186/s41021-023-00269-2.pdf
https://link.springer.com/article/10.1186/s41021-023-00269-2/fulltext.html

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2

Academic Journal

Chemical and in vitro toxicological comparison of emissions from a heated tobacco product and the 1R6F reference cigarette

المؤلفون: Hashizume, Tsuneo, Ishikawa, Shinkichi, Matsumura, Kazushi, Ito, Shigeaki, Fukushima, Toshiro

المصدر: Toxicology Reports ; volume 10, page 281-292 ; ISSN 2214-7500

الاتاحة: http://dx.doi.org/10.1016/j.toxrep.2023.02.005
https://api.elsevier.com/content/article/PII:S2214750023000185?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2214750023000185?httpAccept=text/plain

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3

Academic Journal

Exploring the role of oxidative stress and mitochondrial dysfunction in β-damascone-induced aneuploidy.

المؤلفون: Hashizume, Tsuneo¹ (AUTHOR) tsuneo.hashizume@jt.com, Munakata, Satoru¹ (AUTHOR), Takahashi, Tomohiro¹ (AUTHOR), Watanabe, Taku¹ (AUTHOR)

المصدر: Genes & Environment. 11/25/2024, Vol. 46 Issue 1, p1-14. 14p.

مصطلحات موضوعية: *AMES test, *CHROMOSOME segregation, *REACTIVE oxygen species, *MOIETIES (Chemistry), *MEMBRANE potential, *OXIDATIVE stress, *GENETIC toxicology

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4

Academic Journal

Effects of antioxidant capacity on micronucleus induction by cigarette smoke in mammalian cells

المؤلفون: Yamamoto, Haruna, Shibuya, Kaori, Fukushima, Toshiro, Hashizume, Tsuneo

المصدر: Mutation Research/Genetic Toxicology and Environmental Mutagenesis ; volume 873, page 503427 ; ISSN 1383-5718

الاتاحة: http://dx.doi.org/10.1016/j.mrgentox.2021.503427
https://api.elsevier.com/content/article/PII:S1383571821001182?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1383571821001182?httpAccept=text/plain

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5

Academic Journal

Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS

المساهمون: Ministry of Health, Labour and Welfare

المصدر: Genes and Environment ; volume 43, issue 1 ; ISSN 1880-7062

الاتاحة: http://dx.doi.org/10.1186/s41021-021-00179-1
https://link.springer.com/content/pdf/10.1186/s41021-021-00179-1.pdf
https://link.springer.com/article/10.1186/s41021-021-00179-1/fulltext.html

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6

Academic Journal

Development of an In Vitro Sensitisation Test Using a Coculture System of Human Bronchial Epithelium and Immune Cells

المؤلفون: Tanabe, Ikuya, Yoshida, Kunitaka, Ishikawa, Shinkichi, Ishimori, Kanae, Hashizume, Tsuneo, Yoshimoto, Takayuki, Ashikaga, Takao

المصدر: Alternatives to Laboratory Animals ; volume 51, issue 6, page 387-400 ; ISSN 0261-1929 2632-3559

الاتاحة: http://dx.doi.org/10.1177/02611929231204823
http://journals.sagepub.com/doi/pdf/10.1177/02611929231204823
http://journals.sagepub.com/doi/full-xml/10.1177/02611929231204823

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7

Academic Journal

Key Challenges and Recommendations for In Vitro Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters

المساهمون: U.S. Food and Drug Administration, Institute for In Vitro Sciences, Education and Outreach Program

المصدر: Alternatives to Laboratory Animals ; volume 51, issue 1, page 55-79 ; ISSN 0261-1929 2632-3559

الاتاحة: http://dx.doi.org/10.1177/02611929221146536
http://journals.sagepub.com/doi/pdf/10.1177/02611929221146536
http://journals.sagepub.com/doi/full-xml/10.1177/02611929221146536

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8

Academic Journal

Meeting report, ICH M7 relevant workshop: use of (Q)SAR systems and expert judgment

المؤلفون: Mishima, Masayuki, Hashizume, Tsuneo, Haranosono, Yu, Nagato, Yusuke, Takeshita, Kentaro, Fukuchi, Junichi, Homma, Masamitsu

المساهمون: Japan Agency for Medical Research and Development

المصدر: Genes and Environment ; volume 40, issue 1 ; ISSN 1880-7062

الاتاحة: http://dx.doi.org/10.1186/s41021-018-0107-2
http://link.springer.com/content/pdf/10.1186/s41021-018-0107-2.pdf
http://link.springer.com/article/10.1186/s41021-018-0107-2/fulltext.html

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9

Periodical

Development of an In VitroSensitisation Test Using a Coculture System of Human Bronchial Epithelium and Immune Cells

المؤلفون: Tanabe, Ikuya, Yoshida, Kunitaka, Ishikawa, Shinkichi, Ishimori, Kanae, Hashizume, Tsuneo, Yoshimoto, Takayuki, Ashikaga, Takao

المصدر: Alternatives to Laboratory Animals; November 2023, Vol. 51 Issue: 6 p387-400, 14p

10

Academic Journal

Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens

المؤلفون: Morita, Takeshi, Hamada, Shuichi, Masumura, Kenichi, Wakata, Akihiro, Maniwa, Jiro, Takasawa, Hironao, Yasunaga, Katsuaki, Hashizume, Tsuneo, Honma, Masamitsu

المساهمون: Health and Labor Sciences Research

المصدر: Mutation Research/Genetic Toxicology and Environmental Mutagenesis ; volume 802, page 1-29 ; ISSN 1383-5718

الاتاحة: http://dx.doi.org/10.1016/j.mrgentox.2016.03.008
https://api.elsevier.com/content/article/PII:S138357181530019X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S138357181530019X?httpAccept=text/plain

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11

Academic Journal

The utility of metabolic activation mixtures containing human hepatic post-mitochondrial supernatant (S9) forin vitrogenetic toxicity assessment

المؤلفون: Cox, Julie A., Fellows, Mick D., Hashizume, Tsuneo, White, Paul A.

المصدر: Mutagenesis ; volume 31, issue 2, page 117-130 ; ISSN 0267-8357 1464-3804

الاتاحة: http://dx.doi.org/10.1093/mutage/gev082
http://academic.oup.com/mutage/article-pdf/31/2/117/17087397/gev082.pdf

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12

Comparative Evaluation of a Solvent-Free Squeezing Method for Concentrated Aerosol Collected Mass Extracts from Electronic Cigarettes and Heated Tobacco Products

المؤلفون: Ito, Hiroshi, Shigeto, Atsushi, Hashizume, Tsuneo

الاتاحة: http://dx.doi.org/10.2139/ssrn.4681558

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13

Additional file 4 of Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS

مصطلحات موضوعية: Data_FILES

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623368d4831d9655c7a619b6d5dedc72

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14

Academic Journal

Application of a New Genotoxicity Test System with Human Hepatocyte Cell Lines to Improve the Risk Assessment in the Drug Development

المؤلفون: Hashizume, Tsuneo

المصدر: MODID-6d55e02e354:IntechOpen

مصطلحات موضوعية: Medical / Toxicology, bisacsh:MED096000

وصف الملف: application/pdf

Relation: https://openresearchlibrary.org/viewer/5e8e1acf-8cc9-42a5-8f93-6f3cbdca1cf2; https://openresearchlibrary.org/ext/api/media/5e8e1acf-8cc9-42a5-8f93-6f3cbdca1cf2/assets/external_content.pdf

الاتاحة: https://openresearchlibrary.org/viewer/5e8e1acf-8cc9-42a5-8f93-6f3cbdca1cf2
https://openresearchlibrary.org/ext/api/media/5e8e1acf-8cc9-42a5-8f93-6f3cbdca1cf2/assets/external_content.pdf
https://doi.org/10.5772/31779

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15

Academic Journal

Advantages of Human Hepatocyte-Derived Transformants Expressing a Series of Human Cytochrome P450 Isoforms for Genotoxicity Examination

المؤلفون: Hashizume, Tsuneo, Yoshitomi, Sumie, Asahi, Satoru, Uematsu, Rieko, Matsumura, Shigeo, Chatani, Fumio, Oda, Hiroaki

مصطلحات موضوعية: GENETIC TOXICOLOGY

وصف الملف: text/html

Relation: http://toxsci.oxfordjournals.org/cgi/content/short/116/2/488; http://dx.doi.org/10.1093/toxsci/kfq154

الاتاحة: http://toxsci.oxfordjournals.org/cgi/content/short/116/2/488
https://doi.org/10.1093/toxsci/kfq154

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16

Periodical

Key Challenges and Recommendations for In VitroTesting of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters

المصدر: Alternatives to Laboratory Animals; January 2023, Vol. 51 Issue: 1 p55-79, 25p

17

Academic Journal

Workshop Series to Identify, Discuss, and Develop Recommendations for the Optimal Generation and Use of In Vitro Assay Data for Tobacco Product Evaluation: Phase 1 Genotoxicity Assays

المصدر: Applied In Vitro Toxicology ; volume 6, issue 2, page 49-63 ; ISSN 2332-1512 2332-1539

الاتاحة: http://dx.doi.org/10.1089/aivt.2020.0004
https://www.liebertpub.com/doi/full-xml/10.1089/aivt.2020.0004
https://www.liebertpub.com/doi/pdf/10.1089/aivt.2020.0004

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18

Academic Journal

Bilirubin Oxidation Provoked by Endotoxins Treatment is Suppressed by Feeding Ascorbic Acid in a Rat Mutant Unable to Synthesize Ascorbic Acid

المؤلفون: Yamaguchi, Tokio, Hashizume, Tsuneo, Tanaka, Makiko, Nakayama, Mitsuyo, Sugimoto, Akiko, Ikeda, Saiko, Nakajima, Hiroshi, Horio, Fumihiko

المصدر: European Journal of Biochemistry ; volume 245, issue 2, page 233-240 ; ISSN 0014-2956 1432-1033

الاتاحة: http://dx.doi.org/10.1111/j.1432-1033.1997.00233.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1432-1033.1997.00233.x
https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1432-1033.1997.00233.x

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19

Academic Journal

Pyrene did not induce gene mutation in red blood cell Pig-a assay and PIGRET assay in rats

المؤلفون: Yoshida, Ikuma, Matsumoto, Akemi, Sakai, Yumi, Harada, Yumiko, Hashizume, Tsuneo

المصدر: Mutation Research/Genetic Toxicology and Environmental Mutagenesis ; volume 811, page 49-53 ; ISSN 1383-5718

الاتاحة: http://dx.doi.org/10.1016/j.mrgentox.2016.04.007
https://api.elsevier.com/content/article/PII:S138357181630105X?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S138357181630105X?httpAccept=text/xml

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20

Academic Journal

Red blood cell Pig-a assay and PIGRET assay in rats with azathioprine

المؤلفون: Yoshida, Ikuma, Matsumoto, Akemi, Sakai, Yumi, Harada, Yumiko, Hashizume, Tsuneo

المصدر: Mutation Research/Genetic Toxicology and Environmental Mutagenesis ; volume 811, page 60-64 ; ISSN 1383-5718

الاتاحة: http://dx.doi.org/10.1016/j.mrgentox.2016.01.009
https://api.elsevier.com/content/article/PII:S1383571816300213?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S1383571816300213?httpAccept=text/xml

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