يعرض 1 - 20 نتائج من 247 نتيجة بحث عن '"Haruhisa Kikuchi"', وقت الاستعلام: 0.58s تنقيح النتائج
  1. 1
    Academic Journal
    Isolation and Structure Determination of New Pyrones from Dictyostelium spp. Cellular Slime Molds Coincubated with Pseudomonas spp.

    المؤلفون: Takehiro Nishimura, Takuya Murotani, Hitomi Sasaki, Yoshinori Uekusa, Hiromi Eguchi, Hirotaka Ishigaki, Katsunori Takahashi, Yuzuru Kubohara, Haruhisa Kikuchi

    المصدر: Molecules, Vol 29, Iss 9, p 2143 (2024)

    مصطلحات موضوعية: cellular smile molds, natural products, Pseudomonas spp., coincubation, α-pyrone, phenolic compound, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1420-3049/29/9/2143; https://doaj.org/toc/1420-3049

    URL الوصول: https://doaj.org/article/1dcef92ec80043a0923bb7bd76adcca5

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  2. 2
    Academic Journal
    Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic–polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells

    المؤلفون: Liu Xu, Zaiqiang Yu, Yoshinori Uekusa, Shogo Kawaguchi, Haruhisa Kikuchi, Kazuyuki Daitoku, Masahito Minakawa, Shigeru Motomura, Ken-Ichi Furukawa, Yoshiteru Oshima, Kazuhiko Seya, Tadaatsu Imaizumi

    المصدر: Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 147-157 (2022)

    مصطلحات موضوعية: Cerebral microvascular endothelial cells, Nuclear factor-ĸB, Interferon-β, CXCL10, (+)-hopeaphenol, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S134786132200038X; https://doaj.org/toc/1347-8613

    URL الوصول: https://doaj.org/article/449ae64accd9433da99b02a2ffd174cd

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  3. 3
    Academic Journal
    Pharmacological Evidence That Dictyostelium Differentiation-Inducing Factor 1 Promotes Glucose Uptake Partly via an Increase in Intracellular cAMP Content in Mouse 3T3-L1 Cells

    المؤلفون: Yuzuru Kubohara, Yuko Fukunaga, Haruhisa Kikuchi, Hidekazu Kuwayama

    المصدر: Molecules, Vol 28, Iss 23, p 7926 (2023)

    مصطلحات موضوعية: Dictyostelium discoideum, DIF-1, obesity, diabetes, PDE1, cAMP, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1420-3049/28/23/7926; https://doaj.org/toc/1420-3049

    URL الوصول: https://doaj.org/article/8624b57ef09a459e8ff6170bbdd87d87

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  4. 4
    Academic Journal
    Dictyostelium Differentiation-inducing Factor Derivatives Reduce the Glycosylation of PD-L1 in MDA-MB-231 Human Breast Cancer Cells

    المؤلفون: AIRI HIRAYAMA, HARUHISA KIKUCHI, HIROTAKA ISHIGAKI, KATSUNORI TAKAHASHI, YUSUKE MIURA, YUZURU KUBOHARA

    المصدر: Juntendo Medical Journal. 2023, 69(2):105

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  5. 5
    Academic Journal
    Derivatives of Differentiation-Inducing Factor 1 Differentially Control Chemotaxis and Stalk Cell Differentiation in Dictyostelium discoideum

    المؤلفون: Hidekazu Kuwayama, Haruhisa Kikuchi, Yuzuru Kubohara

    المصدر: Biology, Vol 12, Iss 6, p 873 (2023)

    مصطلحات موضوعية: Dictyostelium, DIF, GbpB, RegA, RdeA, DhkC, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2079-7737/12/6/873; https://doaj.org/toc/2079-7737

    URL الوصول: https://doaj.org/article/2f4d300cdadc4cdeb2aa2d997b86366e

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  6. 6
    Academic Journal
    Corrigendum to 'Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinicepolycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells' [Journal of Pharmacological Sciences 149 (2022) 147–157]

    المؤلفون: Liu Xu, Zaiqiang Yu, Yoshinori Uekusa, Shogo Kawaguchi, Haruhisa Kikuchi, Kazuyuki Daitoku, Masahito Minakawa, Shigeru Motomura, Ken-Ichi Furukawa, Yoshiteru Oshima, Kazuhiko Seya, Tadaatsu Imaizumi

    المصدر: Journal of Pharmacological Sciences, Vol 151, Iss 1, Pp 63-64 (2023)

    مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S1347861322000688; https://doaj.org/toc/1347-8613

    URL الوصول: https://doaj.org/article/d99d7f955bd049888b5a7d03a9abd3c9

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  7. 7
    Academic Journal
    Development of Indole Alkaloid-Type Dual Immune Checkpoint Inhibitors Against CTLA-4 and PD-L1 Based on Diversity-Enhanced Extracts

    المؤلفون: Yoshihide Suzuki, Keisuke Ichinohe, Akihiro Sugawara, Shinya Kida, Shinya Murase, Jing Zhang, Osamu Yamada, Toshio Hattori, Yoshiteru Oshima, Haruhisa Kikuchi

    المصدر: Frontiers in Chemistry, Vol 9 (2021)

    مصطلحات موضوعية: immune checkpoint inhibitors, natural products, indole, PD-L1, CTLA-4, diversity-enhanced extracts, Chemistry, QD1-999

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fchem.2021.766107/full; https://doaj.org/toc/2296-2646

    URL الوصول: https://doaj.org/article/5446e2a977fb434dabf63311a85d4f08

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  8. 8
    Academic Journal
    (+)-Hopeaphenol inhibits Poly IC-induced innate immunity activation via IFN-β in human cerebral microvascular endothelial cells / (+)-ホペアフェノールはヒト脳微小血管内皮細胞において、Poly ICによりインターフェロン-βを介して賦活化する自然免疫を抑制する

    المؤلفون: Haruhisa Kikuchi, Kazuhiko Seya, Kazuyuki Daitoku, Ken-ichi Furukawa, Masahito Minakawa, Shigeru Motomura, Shogo Kawaguchi, Tadaatsu Imaizumi, Xu Liu, Yoshiteru Oshima, Zaiqiang Yu, 于 在強, 今泉 忠淳, 元村 成, 劉 旭, 古川 賢一, 大島 吉輝, 大徳 和之, 川口 章吾, 瀬谷 和彦, 皆川 正仁, 菊地 晴久

    المصدر: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022, :3-194

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  9. 9
    Academic Journal
    Mg, K-containing microparticle: A possible active principle of a culture extract produced by a microbial consortium.

    المؤلفون: Toru Higashinakagawa, Haruhisa Kikuchi, Hidekazu Kuwayama

    المصدر: PLoS ONE, Vol 16, Iss 11, p e0259297 (2021)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1932-6203

    URL الوصول: https://doaj.org/article/62d2d52075824e149094b69d2201c6f0

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  10. 10
    Academic Journal
    Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum

    المؤلفون: Yuzuru Kubohara, Haruhisa Kikuchi, Van Hai Nguyen, Hidekazu Kuwayama, Yoshiteru Oshima

    المصدر: Biology Open, Vol 6, Iss 6, Pp 741-751 (2017)

    مصطلحات موضوعية: Dictyostelium discoideum, DIF-1, DIF-2, Mitochondria, Cell differentiation, Chemotaxis, Science, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://bio.biologists.org/content/6/6/741; https://doaj.org/toc/2046-6390

    URL الوصول: https://doaj.org/article/f3553a57ee7f41b3a480adf0dc1ce0ad

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  11. 11
    Academic Journal
    1-Methyl-2-undecyl-4(1H)-quinolone, a derivative of quinolone alkaloid evocarpine, attenuates high phosphate-induced calcification of human aortic valve interstitial cells by inhibiting phosphate cotransporter PiT-1

    المؤلفون: Kazuhiko Seya, Ken-Ichi Furukawa, Mari Chiyoya, Zaiqiang Yu, Haruhisa Kikuchi, Kazuyuki Daitoku, Shigeru Motomura, Manabu Murakami, Yoshiteru Oshima, Ikuo Fukuda

    المصدر: Journal of Pharmacological Sciences, Vol 131, Iss 1, Pp 51-57 (2016)

    مصطلحات موضوعية: Aortic valve interstitial cells, Calcification, 1-Methyl-2-undecyl-4(1H)-quinolone, High phosphate, PiT-1, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S1347861316300305; https://doaj.org/toc/1347-8613

    URL الوصول: https://doaj.org/article/ca540ecc1243483e87a468490ffdc4d5

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  12. 12
    Academic Journal
    Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds

    المؤلفون: Hitomi Sasaki, Yuzuru Kubohara, Hirotaka Ishigaki, Katsunori Takahashi, Hiromi Eguchi, Akihiro Sugawara, Yoshiteru Oshima, Haruhisa Kikuchi

    المصدر: Molecules, Vol 25, Iss 12, p 2895 (2020)

    مصطلحات موضوعية: cellular slime molds, dictyostelid, natural products, terpenoids, Organic chemistry, QD241-441

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/1420-3049/25/12/2895; https://doaj.org/toc/1420-3049

    URL الوصول: https://doaj.org/article/6ac83fdd4d704b729655b20661467912

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  13. 13
    Academic Journal
    New Development of Disaster-Related and Tropical Infectious Diseases Control

    المؤلفون: Gaowa Bai, Toshiro Niki, Haruhisa Kikuchi, Ayako Sumi, Nobuyuki Kobayashi, Takahiro Haruyama, Jing Zhang, Haorile Chagan-Yasutan, Toshio Hattori

    المصدر: Reports, Vol 3, Iss 1, p 5 (2020)

    مصطلحات موضوعية: disaster, tropical, infectious diseases, global warmings, sth-pas, galectin 9, osteopontin, brefelamide, Medicine (General), R5-920, Medical physics. Medical radiology. Nuclear medicine, R895-920

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2571-841X/3/1/5; https://doaj.org/toc/2571-841X

    URL الوصول: https://doaj.org/article/020cdbd60bd94ed18d452bbaa2fa1297

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  14. 14
    Academic Journal
    Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK4. / プレニルキノリンカルボン酸誘導体は、MKK4の阻害を通して神経細胞死を抑制する。

    المؤلفون: Haruhisa Kikuchi, Junko Yamaki, Masato Ogura, Miwako Homma, Shakespear Norshalena, Toshiyuki Suzuki, Yoshimi Homma, Yoshiteru Oshima, ノーシャリナ シェイクスピア, 八巻 淳子, 大島 吉輝, 小椋 正人, 本間 好, 本間 美和子, 菊地 晴久, 鈴木 俊幸

    المصدر: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2019, :2-38

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  15. 15
    Academic Journal
    Derivatives of Dictyostelium Differentiation-Inducing Factors Inhibit Serum-Dependent Cell Migration of Murine Osteosarcoma LM8 Cells

    المؤلفون: HARUHISA KIKUCHI, YOSHITERU OSHIMA, YUZURU KUBOHARA

    المصدر: Juntendo Medical Journal. 2019, 65(1):71

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  16. 16
    Academic Journal
    Defects in the synthetic pathway prevent DIF-1 mediated stalk lineage specification cascade in the non-differentiating social amoeba, Acytostelium subglobosum

    المؤلفون: Kurato Mohri, Takashi Hata, Haruhisa Kikuchi, Yoshiteru Oshima, Hideko Urushihara

    المصدر: Biology Open, Vol 3, Iss 6, Pp 553-560 (2014)

    مصطلحات موضوعية: Cell differentiation, Cellular slime mold, Polyketide signaling, Gene expression, Functional complementation, Science, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://bio.biologists.org/content/3/6/553; https://doaj.org/toc/2046-6390

    URL الوصول: https://doaj.org/article/f4657f6808dd4dfd91feaeed697a5d95

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  17. 17
    Academic Journal
    Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum

    المؤلفون: Yuzuru Kubohara, Haruhisa Kikuchi, Yusuke Matsuo, Yoshiteru Oshima, Yoshimi Homma

    المصدر: Biology Open, Vol 3, Iss 4, Pp 289-296 (2014)

    مصطلحات موضوعية: Dictyostelium discoideum, DIF, Anti-tumor agent, Mitochondria, Uncoupler, Science, Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://bio.biologists.org/content/3/4/289; https://doaj.org/toc/2046-6390

    URL الوصول: https://doaj.org/article/4ba991cf97aa4072a643ea62328e0e35

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  18. 18
    Academic Journal
    Halogen-Substituted Derivatives of Dictyostelium Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro

    المؤلفون: Kyoko Totsuka, Yuka Makioka, Kyoichi Iizumi, Katsunori Takahashi, Yoshiteru Oshima, Haruhisa Kikuchi, Yuzuru Kubohara

    المصدر: Biomolecules, Vol 9, Iss 7, p 256 (2019)

    مصطلحات موضوعية: triple-negative breast cancer, metastasis, cell migration, anticancer drug, Dictyostelium discoideum, DIF, Microbiology, QR1-502

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2218-273X/9/7/256; https://doaj.org/toc/2218-273X

    URL الوصول: https://doaj.org/article/8166925703094011bd0ec499f0f7457e

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  19. 19
    Academic Journal
    Antimicrobial Activities of Dictyostelium Differentiation-Inducing Factors and Their Derivatives

    المؤلفون: Yuzuru Kubohara, Yoshiko Shiratsuchi, Hirotaka Ishigaki, Katsunori Takahashi, Yoshiteru Oshima, Haruhisa Kikuchi

    المصدر: Biomolecules, Vol 9, Iss 5, p 163 (2019)

    مصطلحات موضوعية: antimicrobial, Dictyostelium discoideum, DIF, MRSA, VRE, Microbiology, QR1-502

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2218-273X/9/5/163; https://doaj.org/toc/2218-273X

    URL الوصول: https://doaj.org/article/8e63411b99b4462c8c0e1fae2977df52

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  20. 20
    Academic Journal
    Biological Activities of Novel Derivatives of Differentiation-Inducing Factor 3 from Dictyostelium discoideum

    المؤلفون: Haruhisa Kikuchi, Hirotaka Ishigaki, Junko Nakajima-Shimada, Katsunori Takahashi, Van Hai Nguyen, Yoshiteru Oshima, Yuzuru Kubohara

    المصدر: Biological and Pharmaceutical Bulletin. 2017, 40(11):1941

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