المؤلفون: Guri-Lamce, I, Alrokh, Y, Graham, C, Maeshima, R, Rognoni, E, Caley, M, Łaczmański, Ł, Hart, SL, McGrath, JA, Jacków-Malinowska, J

مصطلحات موضوعية: Epidermolysis bullosa, Gene editing, Gene therapy, Lipid nanoparticles

Relation: J Invest Dermatol; Ina Guri-Lamce, Yara Alrokh, Carina Graham, Ruhina Maeshima, Emanuel Rognoni, Matthew Caley, Łukasz Łaczmański, Stephen L. Hart, John A. McGrath, Joanna Jacków-Malinowska, Lipid Nanoparticles Efficiently Deliver the Base Editor ABE8e for COL7A1 Correction in Dystrophic Epidermolysis Bullosa Fibroblasts In Vitro, Journal of Investigative Dermatology, 2024, , ISSN 0022-202X, https://doi.org/10.1016/j.jid.2024.03.027. (https://www.sciencedirect.com/science/article/pii/S0022202X24002690) Keywords: Epidermolysis bullosa; Gene editing; Gene therapy; Lipid nanoparticles; https://qmro.qmul.ac.uk/xmlui/handle/123456789/96502

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96502
https://doi.org/10.1016/j.jid.2024.03.027

المؤلفون: Walker, AJ, Graham, C, Greenwood, M, Woodall, M, Maeshima, R, O'Hara-Wright, M, Sanz, DJ, Guerrini, I, Aldossary, AM, O'Callaghan, C, Baines, DL, Harrison, PT, Hart, SL

وصف الملف: application/pdf; application/vnd.ms-excel

Relation: https://openaccess.sgul.ac.uk/id/eprint/116011/1/1-s2.0-S2329050123001791-main.pdf; https://openaccess.sgul.ac.uk/id/eprint/116011/6/1-s2.0-S2329050123001791-mmc1.pdf; https://openaccess.sgul.ac.uk/id/eprint/116011/11/1-s2.0-S2329050123001791-mmc2.xlsx; https://openaccess.sgul.ac.uk/id/eprint/116011/12/1-s2.0-S2329050123001791-mmc3.xlsx; https://openaccess.sgul.ac.uk/id/eprint/116011/13/1-s2.0-S2329050123001791-mmc4.xlsx; https://openaccess.sgul.ac.uk/id/eprint/116011/14/1-s2.0-S2329050123001791-mmc5.xlsx; Walker, AJ; Graham, C; Greenwood, M; Woodall, M; Maeshima, R; O'Hara-Wright, M; Sanz, DJ; Guerrini, I; Aldossary, AM; O'Callaghan, C; et al. Walker, AJ; Graham, C; Greenwood, M; Woodall, M; Maeshima, R; O'Hara-Wright, M; Sanz, DJ; Guerrini, I; Aldossary, AM; O'Callaghan, C; Baines, DL; Harrison, PT; Hart, SL (2023) Molecular and functional correction of a deep intronic splicing mutation in CFTR by CRISPR-Cas9 gene editing. Mol Ther Methods Clin Dev, 31. p. 101140. ISSN 2329-0501 https://doi.org/10.1016/j.omtm.2023.101140 SGUL Authors: Baines, Deborah

الاتاحة: https://openaccess.sgul.ac.uk/id/eprint/116011/
https://openaccess.sgul.ac.uk/id/eprint/116011/1/1-s2.0-S2329050123001791-main.pdf
https://openaccess.sgul.ac.uk/id/eprint/116011/6/1-s2.0-S2329050123001791-mmc1.pdf
https://openaccess.sgul.ac.uk/id/eprint/116011/11/1-s2.0-S2329050123001791-mmc2.xlsx
https://openaccess.sgul.ac.uk/id/eprint/116011/12/1-s2.0-S2329050123001791-mmc3.xlsx
https://openaccess.sgul.ac.uk/id/eprint/116011/13/1-s2.0-S2329050123001791-mmc4.xlsx
https://openaccess.sgul.ac.uk/id/eprint/116011/14/1-s2.0-S2329050123001791-mmc5.xlsx
https://doi.org/10.1016/j.omtm.2023.101140

المؤلفون: Lee, DDH, Cardinale, D, Nigro, E, Butler, CR, Rutman, A, Fassad, MR, Hirst, RA, Moulding, D, Agrotis, A, Forsythe, E, Peckham, D, Robson, E, Smith, CM, Somavarapu, S, Beales, PL, Hart, SL, Janes, SM, Mitchison, HM, Ketteler, R, Hynds, RE, O'Callaghan, C

المصدر: European Respiratory Journal (2021) (In press).

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10126062/1/13993003.00455-2020.full.pdf; https://discovery.ucl.ac.uk/id/eprint/10126062/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10126062/1/13993003.00455-2020.full.pdf
https://discovery.ucl.ac.uk/id/eprint/10126062/

المؤلفون: Tagalakis AD, Jayarajan V, Maeshima R, Ho KH, Syed F, Wu L-P, Aldossary AM, Munye MM, Mistry T, Ogunbiyi OK, Sala A, Standing JF, Moghimi SM, Stoker AW, Hart SL

المصدر: Advanced Functional Materials, 2021

وصف الملف: application/pdf

Relation: https://eprints.ncl.ac.uk/275850; https://eprints.ncl.ac.uk/fulltext.aspx?url=275850/8E03FF39-42DE-48FE-9B17-D137C22E132C.pdf&pub_id=275850

الاتاحة: https://eprints.ncl.ac.uk/275850

المؤلفون: Tagalakis, AD, Jayarajan, V, Maeshima, R, Ho, KH, Syed, F, Wu, L-P, Aldossary, AM, Munye, MM, Mistry, T, Ogunbiyi, OK, Sala, A, Standing, JF, Moghimi, SM, Stoker, AW, Hart, SL

مصطلحات موضوعية: MYCN, neuroblastomas, siRNA, tumor-specific delivery, tumors

وصف الملف: 1 - 12; Print-Electronic

Relation: Advanced Functional Materials; ORCID iD: Aristides D. Tagalakis orcid:0000-0002-4610-0803; ORCID iD: Ruhina Maeshima orcid:0000-0003-1473-9757; ORCID iD: Arturo Sala orcid:0000-0002-2841-7866; ORCID iD: Stephen L. Hart orcid:0000-0001-8254-376X; 2104843; Tagalakis, A.D. et al. (2021) 'Integrin-Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival', Advanced Functional Materials, 31 (37), 2104843, pp. 1 - 12. doi:10.1002/adfm.202104843.; https://bura.brunel.ac.uk/handle/2438/28252; https://doi.org/10.1002/adfm.202104843

الاتاحة: https://bura.brunel.ac.uk/handle/2438/28252
https://doi.org/10.1002/adfm.202104843

المؤلفون: Hart, SL, Walker, AJ

المساهمون: Hoeger, PH, Kinsler, V, Yan, AC, Harper, J, Oranje, AP, Bodemer, C, Larralde, M, luk, D, Mendiratta, V, Purvis, D

المصدر: In: Hoeger, PH and Kinsler, V and Yan, AC and Harper, J and Oranje, AP and Bodemer, C and Larralde, M and luk, D and Mendiratta, V and Purvis, D, (eds.) Harper's Textbook of Pediatric Dermatology, 2 Volume Set. Wiley-Blackwell (2019) (In press).

مصطلحات موضوعية: Medical

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10085846/13/Tabel%201.pdf; https://discovery.ucl.ac.uk/id/eprint/10085846/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10085846/13/Tabel%201.pdf
https://discovery.ucl.ac.uk/id/eprint/10085846/

المؤلفون: Maeshima, R, Moulding, D, Stoker, AW, Hart, SL

المصدر: Nucleic Acid Therapeutics , 30 (4) pp. 237-248. (2020)

مصطلحات موضوعية: MYCN, neuroblastoma, retinoic acid treatment, siRNA

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10094643/3/Hart_MYCN%20Silencing%20by%20RNA%20Interference%20Induces%20Neurogenesis%20and%20Suppresses%20Proliferation%20in%20Models%20of%20Neuroblastoma%20with%20Resistance%20to%20Retinoic%20Acid_AAM.pdf; https://discovery.ucl.ac.uk/id/eprint/10094643/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10094643/3/Hart_MYCN%20Silencing%20by%20RNA%20Interference%20Induces%20Neurogenesis%20and%20Suppresses%20Proliferation%20in%20Models%20of%20Neuroblastoma%20with%20Resistance%20to%20Retinoic%20Acid_AAM.pdf
https://discovery.ucl.ac.uk/id/eprint/10094643/

المؤلفون: Meng, J, Tagalakis, AD, Hart, SL

المصدر: Scientific Reports , 10 (1) , Article 1046. (2020)

مصطلحات موضوعية: Cancer therapy, Drug delivery

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10090316/7/Hart_s41598-020-57854-6.pdf; https://discovery.ucl.ac.uk/id/eprint/10090316/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10090316/7/Hart_s41598-020-57854-6.pdf
https://discovery.ucl.ac.uk/id/eprint/10090316/

المؤلفون: Boyd, AC, Guo, S, Huang, L, Kerem, B, Oren, YS, Walker, AJ, Hart, SL

المصدر: Journal of Cystic Fibrosis , 19 (S1) S54-S59. (2020)

مصطلحات موضوعية: Cystic fibrosis, Gene therapy, Antisense oligonucleotides, siRNA, mRNA splicing, ENaC, CFTR, Liposomes, Nanoparticles

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10090183/1/JCF%20Review%20Markup.pdf; https://discovery.ucl.ac.uk/id/eprint/10090183/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10090183/1/JCF%20Review%20Markup.pdf
https://discovery.ucl.ac.uk/id/eprint/10090183/

المؤلفون: Bilip, M, Shah, S, Mathiyalakan, M, Tagalakis, A, Hart, SL, Maeshima, R, Eaton, S, Orford, M, Irving, E, Di Florio, A, Simons, C, Stoker, AW

المصدر: Journal of Drug Targeting (2020) (In press).

مصطلحات موضوعية: Neuroblastoma, retinoic acid, liposome, RAMBA, CYP26, neural differentiation

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10089044/8/Stoker_Liposomal%20delivery%20of%20hydrophobic%20RAMBAs%20provides%20good%20bioavailability%20and%20significant%20enhancement%20of%20retinoic%20acid%20signalling%20in%20neuroblastoma_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10089044/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10089044/8/Stoker_Liposomal%20delivery%20of%20hydrophobic%20RAMBAs%20provides%20good%20bioavailability%20and%20significant%20enhancement%20of%20retinoic%20acid%20signalling%20in%20neuroblastoma_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10089044/

المؤلفون: Lee, MY, Wang, H-Z, White, TW, Brooks, T, Pittman, A, Halai, H, Petrova, A, Xu, D, Hart, SL, Kinsler, VA, Di, W-L

المصدر: Journal of Investigative Dermatology , 140 (5) 1035-1044.e7. (2020)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10086366/1/Accepted%20version-siRNA%20and%20KIDJID-2019-0132.R2_Proof_hi.pdf; https://discovery.ucl.ac.uk/id/eprint/10086366/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10086366/1/Accepted%20version-siRNA%20and%20KIDJID-2019-0132.R2_Proof_hi.pdf
https://discovery.ucl.ac.uk/id/eprint/10086366/

المؤلفون: Mohammadi, A, Kudsiova, L, Mustapa, MFM, Campbell, F, Vlaho, D, Welser, K, Story, H, Tagalakis, AD, Hart, SL, Barlow, DJ, Tabor, AB, Lawrence, MJ, Hailes, HC

المصدر: Organic and Biomolecular Chemistry (2019)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10065977/1/c8ob02374c.pdf; https://discovery.ucl.ac.uk/id/eprint/10065977/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10065977/1/c8ob02374c.pdf
https://discovery.ucl.ac.uk/id/eprint/10065977/

المؤلفون: Tagalakis AD, Castellaro S, Zhou H, Bienemann A, Munye MM, McCarthy D, White EA, Hart SL

المصدر: International Journal of Nanomedicine, Vol 2015, Iss default, Pp 2673-2683 (2015)

مصطلحات موضوعية: Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.dovepress.com/a-method-for-concentrating-lipid-peptide-dna-and-sirna-nanocomplexes-t-peer-reviewed-article-IJN; https://doaj.org/toc/1178-2013

URL الوصول: https://doaj.org/article/e507afb0fc094f9b8e4391e87909d112

المؤلفون: Tagalakis, AD, Munye, MM, Ivanova, R, Chen, H, Smith, CM, Aldossary, AM, Rosa, LZ, Moulding, D, Barnes, JL, Kafetzis, KN, Jones, SA, Baines, DL, Moss, GWJ, O'Callaghan, C, McAnulty, RJ, Hart, SL

المصدر: Thorax , 73 (9) pp. 847-856. (2018)

مصطلحات موضوعية: airway epithelium, cystic fibrosis, lung physiology, nebuliser therapy

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10048919/1/thoraxjnl-2017-210670.full.pdf; https://discovery.ucl.ac.uk/id/eprint/10048919/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10048919/1/thoraxjnl-2017-210670.full.pdf
https://discovery.ucl.ac.uk/id/eprint/10048919/

المؤلفون: Hart, SL, Harrison, PT

المصدر: Current Opinion in Pharmacology , 34 pp. 119-124. (2017)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10048264/3/Hart_revised_checked.pdf; https://discovery.ucl.ac.uk/id/eprint/10048264/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10048264/3/Hart_revised_checked.pdf
https://discovery.ucl.ac.uk/id/eprint/10048264/

المؤلفون: Yu Wai Man, C, Tagalakis, AD, Meng, JH, Bouremel, Y, Lee, RM, Virasami, A, Hart, SL, Khaw, PT

المصدر: JAMA Ophthalmology , 135 (11) pp. 1147-1155. (2017)

Relation: https://discovery.ucl.ac.uk/id/eprint/1575453/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1575453/

المؤلفون: Yu-Wai-Man, C, Owen, N, Lees, J, Tagalakis, AD, Hart, SL, Webster, AR, Orengo, CA, Khaw, PT

المصدر: Scientific Reports , 7 , Article 5644. (2017)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1565310/1/Yu-Wai-Man%20et%20al.%20Sci%20Rep%202017%20Jul%2017.pdf; https://discovery.ucl.ac.uk/id/eprint/1565310/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1565310/1/Yu-Wai-Man%20et%20al.%20Sci%20Rep%202017%20Jul%2017.pdf
https://discovery.ucl.ac.uk/id/eprint/1565310/

المؤلفون: Manunta, MDI, Tagalakis, AD, Attwood, M, Aldossary, AM, Barnes, JL, Munye, MM, Weng, A, McAnulty, RJ, Hart, SL

المصدر: Scientific Reports , 7 , Article 700. (2017)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1551443/1/Manunta_Delivery_ENaC_siRNA.pdf; https://discovery.ucl.ac.uk/id/eprint/1551443/6/Manunta_Delivery_ENaC_siRNA_Suppl.pdf; https://discovery.ucl.ac.uk/id/eprint/1551443/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1551443/1/Manunta_Delivery_ENaC_siRNA.pdf
https://discovery.ucl.ac.uk/id/eprint/1551443/6/Manunta_Delivery_ENaC_siRNA_Suppl.pdf
https://discovery.ucl.ac.uk/id/eprint/1551443/

المؤلفون: Hart, SL

المصدر: Gene Therapy , 24 (3) p. 121. (2017)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1549930/1/Hart_My%20editoral%5B1%5D.pdf; https://discovery.ucl.ac.uk/id/eprint/1549930/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1549930/1/Hart_My%20editoral%5B1%5D.pdf
https://discovery.ucl.ac.uk/id/eprint/1549930/

المؤلفون: Munye, MM, Shoemark, A, Hirst, RA, Delhove, JM, Sharp, TV, McKay, TR, O'Callaghan, C, Baines, DL, Howe, SJ, Hart, SL

المصدر: American Journal of Physiology - Lung Cellular and Molecular Physiology , 312 (2) L258-L267. (2017)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1532719/1/nPpj9k-100856_1_merged_1481648415%20copy.pdf; https://discovery.ucl.ac.uk/id/eprint/1532719/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1532719/1/nPpj9k-100856_1_merged_1481648415%20copy.pdf
https://discovery.ucl.ac.uk/id/eprint/1532719/