المؤلفون: Scott A. Becker, Brian G. Petrich, Bing Yu, Kristopher A. Knight, Harrison C. Brown, Sunil S. Raikar, Christopher B. Doering, H. Trent Spencer

المصدر: Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 145-157 (2023)

مصطلحات موضوعية: CAR T cells, bispecific T cell engager, gamma delta T cells, cancer immunotherapy, electroporation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770523000402; https://doaj.org/toc/2372-7705

URL الوصول: https://doaj.org/article/53f3291d08774bab9a7136bad26a24d2

المؤلفون: Gianna M. Branella, Jasmine Y. Lee, Jennifer Okalova, Kiran K. Parwani, Jordan S. Alexander, Raquel F. Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C. Brown, Shanmuganathan Chandrakasan, Brian G. Petrich, Christopher B. Doering, H. Trent Spencer

المصدر: Frontiers in Immunology, Vol 14 (2023)

مصطلحات موضوعية: acute myeloid leukemia (AML), gamma delta (γδ) T cells, ligand-based therapeutics, chimeric antigen receptor (CAR), secreted bispecific T cell engager, stem cell factor (SCF), Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1294555/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/075381e09c6f4fada8ebe38297960f22

المؤلفون: Sandeep R.P. Kumar, Jun Xie, Shilang Hu, Jihye Ko, Qifeng Huang, Harrison C. Brown, Alok Srivastava, David M. Markusic, Christopher B. Doering, H. Trent Spencer, Arun Srivastava, Guangping Gao, Roland W. Herzog

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 98-107 (2021)

مصطلحات موضوعية: adeno-associated virus, AAV, hemophilia, factor IX, liver, non-human primate, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121001273; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/c8c0531282d4473082e53448b9e6d260

المؤلفون: Harrison C. Brown, Philip M. Zakas, Stephan N. George, Ernest T. Parker, H. Trent Spencer, Christopher B. Doering

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 57-69 (2018)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050118300056; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/09423923e0794b1dacf97a03fa3b1882

المؤلفون: Gianna M. Branella, Jasmine Y. Lee, Jennifer Okalova, Kiran K. Parwani, Jordan S. Alexander, Raquel F. Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C. Brown, Shanmuganathan Chandrakasan, Brian G. Petrich, Christopher B. Doering, H. Trent Spencer

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, acute myeloid leukemia (AML), gamma delta (γδ) T cells, ligand-based therapeutics, chimeric antigen receptor (CAR), secreted bispecific T cell engager, stem cell factor (SCF), c-kit (CD117)

Relation: https://figshare.com/articles/dataset/DataSheet_1_Ligand-based_targeting_of_c-kit_using_engineered_T_cells_as_a_strategy_for_treating_acute_myeloid_leukemia_pdf/24550228

الاتاحة: https://doi.org/10.3389/fimmu.2023.1294555.s001
https://figshare.com/articles/dataset/DataSheet_1_Ligand-based_targeting_of_c-kit_using_engineered_T_cells_as_a_strategy_for_treating_acute_myeloid_leukemia_pdf/24550228

المؤلفون: David M. Markusic, Alok Srivastava, Shilang Hu, Qifeng Huang, Roland W. Herzog, Harrison C. Brown, Christopher B. Doering, Guangping Gao, Jun Xie, Arun Srivastava, Jihye Ko, Sandeep R. P. Kumar, H. Trent Spencer

المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 98-107 (2021)

مصطلحات موضوعية: Transgene, Genetic enhancement, non-human primate, adeno-associated virus, QH426-470, Biology, medicine.disease_cause, liver, immune response, hemophilia, Genetics, medicine, capsid, antibodies, Vector (molecular biology), Molecular Biology, Adeno-associated virus, Tropism, Factor IX, factor IX, QH573-671, AAV, Cell biology, Capsid, Molecular Medicine, Original Article, Expression cassette, Cytology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dff1348a9dfcff443a57fa24d9c8e4
http://europepmc.org/articles/PMC8476648

المؤلفون: Allison M Lytle, Harrison C Brown, Na Yoon Paik, Kristopher A Knight, J Fraser Wright, H Trent Spencer, Christopher B Doering

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

Relation: http://www.sciencedirect.com/science/article/pii/S2329050116301462; https://doaj.org/toc/2329-0501; https://doaj.org/article/8d2ed94f878744bcbf391d34f101c04b

الاتاحة: https://doi.org/10.1038/mtm.2015.56
https://doaj.org/article/8d2ed94f878744bcbf391d34f101c04b

المؤلفون: Harrison C Brown, J Fraser Wright, Shangzhen Zhou, Allison M Lytle, Jordan E Shields, H Trent Spencer, Christopher B Doering

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

Relation: http://www.sciencedirect.com/science/article/pii/S2329050116301036; https://doaj.org/toc/2329-0501; https://doaj.org/article/32dbd8a1fba64454a4fdee755b400969

الاتاحة: https://doi.org/10.1038/mtm.2014.36
https://doaj.org/article/32dbd8a1fba64454a4fdee755b400969

المؤلفون: Harrison C. Brown, David M. Markusic, Arun Srivastava, Roland W. Herzog, H. Trent Spencer, Alok Srivastava, Christopher B. Doering, Chen Ling

المصدر: Hum Gene Ther

مصطلحات موضوعية: Serotype, Male, Genetic enhancement, Genetic Vectors, Mice, SCID, Biology, Hemophilia B, Virus, law.invention, Factor IX, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, law, Mice, Inbred NOD, Transduction, Genetic, Genetics, Animals, Humans, Vector (molecular biology), Transgenes, Molecular Biology, Research Articles, 030304 developmental biology, 0303 health sciences, Mice, Inbred C3H, Genetic Therapy, Dependovirus, Virology, In vitro, Mice, Inbred C57BL, Capsid, Liver, 030220 oncology & carcinogenesis, Recombinant DNA, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b912b6f5f342de7c631582d237e9b9
https://europepmc.org/articles/PMC7585622/

المؤلفون: Philip M. Zakas, Harrison C. Brown, H. Trent Spencer, Stephan N. George, Ernest T. Parker, Christopher B. Doering

المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 57-69 (2018)

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, vector optimization, lcsh:QH426-470, Genetic enhancement, Transgene, Cell, Computational biology, Biology, Genome, Article, promoter design, codon optimization, 03 medical and health sciences, Transcription (biology), hemic and lymphatic diseases, hemophilia, Genetics, medicine, lcsh:QH573-671, Molecular Biology, Gene, Messenger RNA, lcsh:Cytology, AAV, lcsh:Genetics, Vector optimization, 030104 developmental biology, medicine.anatomical_structure, factor VIII, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8057961f9965bff41367530909c46bfb
https://pubmed.ncbi.nlm.nih.gov/29552578

المؤلفون: Philip M. Zakas, Kristopher A. Knight, Christopher B. Doering, Harrison C. Brown, H. Trent Spencer, Eric A. Gaucher, Shannon L. Meeks

المصدر: Nature biotechnology

مصطلحات موضوعية: 0301 basic medicine, Protein design, Biomedical Engineering, Bioengineering, Biology, Protein Engineering, Applied Microbiology and Biotechnology, Article, Conserved sequence, 03 medical and health sciences, Molecular evolution, Drug Discovery, Conserved Sequence, Genetics, chemistry.chemical_classification, Factor VIII, Sequence Homology, Amino Acid, Drug discovery, Rational design, Proteins, Drug Synergism, Protein engineering, Directed evolution, Amino acid, 030104 developmental biology, chemistry, Molecular Medicine, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7445e218e0926946ad9a9c0f6ea7383f
https://pubmed.ncbi.nlm.nih.gov/27669166

المؤلفون: Harrison C. Brown, H. Trent Spencer, Allison M Lytle, Christopher B. Doering

المصدر: Molecular Therapy. 23:S95-S96

مصطلحات موضوعية: Pharmacology, congenital, hereditary, and neonatal diseases and abnormalities, biology, business.industry, animal diseases, Genetic enhancement, Immunogenicity, Virus, Titer, Immune system, Antigen, Immunity, hemic and lymphatic diseases, Drug Discovery, Immunology, Genetics, biology.protein, Molecular Medicine, Medicine, Antibody, business, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6576842018ebdb22a5fb3bfbf7b1de9b
https://doi.org/10.1016/s1525-0016(16)33849-7

المؤلفون: Harrison C. Brown, Christopher B. Doering, Eli J. Fine, Ernest T. Parker, H. Trent Spencer

المصدر: Molecular Therapy. 23:S271-S272

مصطلحات موضوعية: Genetics, Pharmacology, Transgene, Biology, Genome, Viral vector, hemic and lymphatic diseases, Codon usage bias, Drug Discovery, Coding region, Molecular Medicine, Vector (molecular biology), Scaffold/matrix attachment region, Gene, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43f4c043f315efd56b0150acfb5c020

المؤلفون: Eric A. Gaucher, Kristopher A. Knight, Ernest T. Parker, H. Trent Spencer, Christopher B. Doering, Philip M. Zakas, Harrison C. Brown

المصدر: Molecular Therapy. 24:S181

مصطلحات موضوعية: Pharmacology, Genetics, congenital, hereditary, and neonatal diseases and abnormalities, In silico, Transgene, Genetic enhancement, Rational design, Computational biology, Transfection, Biology, Directed evolution, Epitope, hemic and lymphatic diseases, Drug Discovery, Molecular Medicine, Molecular Biology, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ac7fd9dbc343b32b5928e791b419b0df
https://doi.org/10.1016/s1525-0016(16)33265-8

المؤلفون: Christopher B. Doering, Stephan N. George, H. Trent Spencer, Phillip M. Zakas, Harrison C. Brown, Ernest T. Parker

المصدر: Molecular Therapy. 24:S287

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Transgene, Genetic enhancement, Translation (biology), Biology, Molecular biology, 03 medical and health sciences, 030104 developmental biology, hemic and lymphatic diseases, Codon usage bias, Drug Discovery, Gene expression, Genetics, Molecular Medicine, Coding region, Vector (molecular biology), Molecular Biology, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e2ad54049d75391b4ea07002a26ed280
https://doi.org/10.1016/s1525-0016(16)33536-5

المؤلفون: Harrison C. Brown, Christopher B. Doering, Bagirath Gangadharan

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, XBP1, Swine, animal diseases, Gene Expression, Golgi Apparatus, Biology, Endoplasmic Reticulum, Biochemistry, Models, Biological, Cell Line, symbols.namesake, hemic and lymphatic diseases, Cricetinae, Protein biosynthesis, Animals, Humans, Secretion, Molecular Biology, Secretory pathway, Factor VIII, Endoplasmic reticulum, Cell Biology, Golgi apparatus, Molecular biology, Recombinant Proteins, Secretory protein, Protein Synthesis and Degradation, Protein Biosynthesis, Unfolded protein response, symbols, Unfolded Protein Response

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b2e9f19e892ee42eee3b380707e061
https://europepmc.org/articles/PMC3129224/

المؤلفون: Harrison C. Brown, Christopher B. Doering, Christine L. Kempton, John F. Healey, Ryan J. Summers, Ernest T. Parker, Shannon L. Meeks, Pete Lollar

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Protein Folding, Protein Conformation, animal diseases, Immunology, Mutant, Intracellular Space, Plasma protein binding, Biology, Hemophilia A, Biochemistry, Antibodies, Thrombosis and Hemostasis, Cell Line, symbols.namesake, Protein structure, Antibody Specificity, hemic and lymphatic diseases, Animals, Humans, Secretion, Factor VIII, Endoplasmic reticulum, Cell Biology, Hematology, Golgi apparatus, Molecular biology, Protein Structure, Tertiary, Amino Acid Substitution, symbols, Protein folding, Mutant Proteins, Extracellular Space, Intracellular, Protein Binding, Subcellular Fractions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a79af324d357c115bba3ae98335e096
https://europepmc.org/articles/PMC3062317/

المؤلفون: Jordan E Shields, Harrison C. Brown, Christopher B. Doering, Shangzhen Zhou, J. Fraser Wright, H. Trent Spencer

المصدر: Blood. 122:4210-4210

مصطلحات موضوعية: education.field_of_study, Viral protein, Transgene, Genetic enhancement, Immunology, Context (language use), Cell Biology, Hematology, Biology, medicine.disease_cause, Biochemistry, Molecular biology, Endothelin 3, Viral vector, law.invention, law, Recombinant DNA, medicine, Vector (molecular biology), education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::da27d2e746b6aee369678bdff85e1fd7
https://doi.org/10.1182/blood.v122.21.4210.4210

المؤلفون: Abdullah Kutlar, Harrison C. Brown, Ferdane Kutlar, Betsy Clair

المصدر: Blood. 118:2145-2145

مصطلحات موضوعية: education.field_of_study, biology, Immunology, Population, Haptoglobin, Cell Biology, Hematology, medicine.disease, Biochemistry, Sickle cell anemia, Pathogenesis, medicine, biology.protein, Hemoglobin, Platelet activation, Endothelial dysfunction, education, CD163

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::54c2f2c7af6ed67a7734ef1010861996
https://doi.org/10.1182/blood.v118.21.2145.2145

المؤلفون: Harrison C. Brown, Betsy Clair, Abdullah Kutlar, Ferdane Kutlar, Philip Sobash

المصدر: Blood. 118:1051-1051

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, education.field_of_study, Immunology, Population, Wild type, Cell Biology, Hematology, Biology, medicine.disease, Biochemistry, Sickle cell anemia, Minor allele frequency, hemic and lymphatic diseases, Fetal hemoglobin, Genotype, Hemoglobin F, medicine, Allele, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d14ab462d0437afb06314986984307f9
https://doi.org/10.1182/blood.v118.21.1051.1051