المؤلفون: Ling Shan, Harm J. Heusinkveld, Kimberly C. Paul, Samantha Hughes, Sirwan K. L. Darweesh, Bastiaan R. Bloem, Judith R. Homberg

المصدر: npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-10 (2023)

مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2373-8057

URL الوصول: https://doaj.org/article/862a3c57c24a4241a9c872cb14337747

المؤلفون: Tamara Tal, Oddvar Myhre, Ellen Fritsche, Joëlle Rüegg, Kai Craenen, Kiara Aiello-Holden, Caroline Agrillo, Patrick J. Babin, Beate I. Escher, Hubert Dirven, Kati Hellsten, Kristine Dolva, Ellen Hessel, Harm J. Heusinkveld, Yavor Hadzhiev, Selma Hurem, Karolina Jagiello, Beata Judzinska, Nils Klüver, Anja Knoll-Gellida, Britta A. Kühne, Marcel Leist, Malene Lislien, Jan L. Lyche, Ferenc Müller, John K. Colbourne, Winfried Neuhaus, Giorgia Pallocca, Bettina Seeger, Ilka Scharkin, Stefan Scholz, Ola Spjuth, Monica Torres-Ruiz, Kristina Bartmann

المصدر: Frontiers in Toxicology, Vol 6 (2024)

مصطلحات موضوعية: new approach method (NAM), developmental neurotoxicity (DNT), adult neurotoxicity (ANT), DNT-IVB, zebrafish, applicability domain, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2024.1359507/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/84a7889b64d34295a7a44cec97e647b1

المؤلفون: Marc Audebert, Ann-Sophie Assmann, Amaya Azqueta, Pavel Babica, Emilio Benfenati, Sylvie Bortoli, Peter Bouwman, Albert Braeuning, Tanja Burgdorf, Xavier Coumoul, Kloé Debizet, Maria Dusinska, Norman Ertych, Jörg Fahrer, Verena Fetz, Ludovic Le Hégarat, Adela López de Cerain, Harm J. Heusinkveld, Kevin Hogeveen, Miriam N. Jacobs, Mirjam Luijten, Giuseppa Raitano, Cynthia Recoules, Elise Rundén-Pran, Mariam Saleh, Iva Sovadinová, Martina Stampar, Lea Thibol, Céline Tomkiewicz, Ariane Vettorazzi, Bob Van de Water, Naouale El Yamani, Bojana Zegura, Michael Oelgeschläger

المصدر: Frontiers in Toxicology, Vol 5 (2023)

مصطلحات موضوعية: non-genotoxic carcinogens, NGTxC, new approach methodologies, NAM, PARC, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2023.1220998/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/bb67b7cd857c45a58747146a121d489d

المؤلفون: Adriana Sofranko, Tina Wahle, Julia Kolling, Harm J. Heusinkveld, Burkhard Stahlmecke, Martin Rosenbruch, Catrin Albrecht, Roel P. F. Schins

المصدر: Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-20 (2022)

مصطلحات موضوعية: Amorphous silica, Nanoceria, Subchronic oral exposure study, Neurobehavioral testing, Neurotoxicity, Alzheimer’s disease, Toxicology. Poisons, RA1190-1270, Industrial hygiene. Industrial welfare, HD7260-7780.8

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1743-8977

URL الوصول: https://doaj.org/article/3bcd6534d49d46fbb10c2f5360f01a66

المؤلفون: Anne Havermans, Edwin P. Zwart, Hans W. J. M. Cremers, Maarten D. M. van Schijndel, Romy S. Constant, Maja Mešković, Laura X. Worutowicz, Jeroen L. A. Pennings, Reinskje Talhout, Leo T. M. van der Ven, Harm J. Heusinkveld

المصدر: Toxics, Vol 9, Iss 10, p 250 (2021)

مصطلحات موضوعية: zebrafish embryo, locomotion behavior, nicotine, nicotinic acetylcholine receptor, neuroadaptation, Chemical technology, TP1-1185

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2305-6304/9/10/250; https://doaj.org/toc/2305-6304

URL الوصول: https://doaj.org/article/74351150c4494a4e9ae6db16f5ed16fa

المؤلفون: Victoria C. de Leeuw, Conny T. M. van Oostrom, Edwin P. Zwart, Harm J. Heusinkveld, Ellen V. S. Hessel

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 4; Pages: 3608

مصطلحات موضوعية: neurotoxicity, neurodegeneration, human embryonic stem cells, dopaminergic neurons, in vitro

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms24043608

الاتاحة: https://doi.org/10.3390/ijms24043608

المؤلفون: Alessandro Atzei, Ingrid Jense, Edwin P. Zwart, Jessica Legradi, Bastiaan J. Venhuis, Leo T.M. van der Ven, Harm J. Heusinkveld, Ellen V.S. Hessel

المصدر: International Journal of Environmental Research and Public Health; Volume 18; Issue 13; Pages: 6717

مصطلحات موضوعية: developmental neurotoxicity (DNT), psychopharmaceuticals, alternative to in vivo test, zebrafish embryo behavioural test, chemical mixtures, environmental and human risk assessment

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/ijerph18136717

الاتاحة: https://doi.org/10.3390/ijerph18136717

المؤلفون: Lennart V.J. van Melis, Harm J. Heusinkveld, Celine Langendoen, Anouk Peters, Remco H.S. Westerink

المساهمون: IRAS OH Toxicology

مصطلحات موضوعية: Neuronal activity, General Neuroscience, Neuroscience(all), Acute and developmental exposure, Microelectrode array (MEA), Calcium imaging, Organophosphate insecticides, Toxicology, In vitro hazard characterisation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c25ba61cff1034c19a1494275f25cf
https://dspace.library.uu.nl/handle/1874/428991

المؤلفون: Yvonne C. M. Staal, Yixuan Li, Lora-Sophie Gerber, Paul Fokkens, Hans Cremers, Flemming R. Cassee, Reinskje Talhout, Remco H. S. Westerink, Harm J. Heusinkveld

المصدر: Inhalation toxicology.

مصطلحات موضوعية: hazard assessment, In vitro, microelectrode array, Health, Toxicology and Mutagenesis, air-liquid interface, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99c667a10fecd64b83f372dd4d56e6cb
https://pubmed.ncbi.nlm.nih.gov/36053669

المؤلفون: Lora-Sophie, Gerber, Harm J, Heusinkveld, Celine, Langendoen, Burkhard, Stahlmecke, Roel Pf, Schins, Remco Hs, Westerink

المصدر: Neurotoxicology. 93

مصطلحات موضوعية: Titanium, Silver, Animals, Metal Nanoparticles, Nanoparticles, Calcium, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::77d932bf5b4f4751b06a2453910a6b33
https://pubmed.ncbi.nlm.nih.gov/36283513

المؤلفون: Harm J. Heusinkveld, Aldert H. Piersma, Yvonne C.M. Staal, George P. Daston, Nancy C. Baker, Thomas B. Knudsen

المصدر: Reprod Toxicol

مصطلحات موضوعية: Neural Tube, Computer science, Neural tube patterning, Systems biology, Notochord, Embryonic Development, Tretinoin, Predictive toxicology, 010501 environmental sciences, Toxicology, Models, Biological, 01 natural sciences, Article, Mesoderm, Mice, 03 medical and health sciences, Ectoderm, Retinoic acid, medicine, Animals, Humans, Computer Simulation, Neural Tube Defects, 030304 developmental biology, 0105 earth and related environmental sciences, Neural Plate, 0303 health sciences, Neural tube defect, Developmental neurotoxicology, Systems Biology, Neural tube, medicine.disease, Crosstalk (biology), medicine.anatomical_structure, Neural Crest, Protein concentration, Signalling pathways, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0886594f2bf68c12ec84bd1488235b3
https://doi.org/10.1016/j.reprotox.2020.09.002

المؤلفون: Harm J. Heusinkveld, Emiel Rorije, Paul F.K. Wackers, Jeroen L. A. Pennings, Mirjam Luijten

المصدر: Chemical Research in Toxicology. 34:452-459

مصطلحات موضوعية: 0303 health sciences, Chemistry, Mechanism (biology), General Medicine, Computational biology, 010501 environmental sciences, Toxicology, 01 natural sciences, In vitro, Transcriptome, 03 medical and health sciences, In vivo, Rat liver, Toxicogenomics, Mode of action, 030304 developmental biology, 0105 earth and related environmental sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2d63b0e49e634e14e006826f4000cefd
https://doi.org/10.1021/acs.chemrestox.0c00313

المؤلفون: Leo T.M. Van Der Ven, Paul Van Ommeren, Edwin P. Zwart, Eric R. Gremmer, Hennie M. Hodemaekers, Harm J. Heusinkveld, Jacob D. van Klaveren, Emiel Rorije

المصدر: Environmental health perspectives. 130(4)

مصطلحات موضوعية: Molecular Docking Simulation, Food, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, Animals, Humans, Complex Mixtures, Risk Assessment, Zebrafish

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496722a8c93f1f98833ae123218ac7e7
https://pubmed.ncbi.nlm.nih.gov/35394809

المؤلفون: Julia J. Meerman, Gerrit Wolterink, Ellen V.S. Hessel, Esther de Jong, Harm J. Heusinkveld

المصدر: Current Opinion in Toxicology. 33:100383

مصطلحات موضوعية: Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7eece20d5dee4feb393ac8ac47cb756c
https://doi.org/10.1016/j.cotox.2022.100383

المؤلفون: Adriana, Sofranko, Tina, Wahle, Julia, Kolling, Harm J, Heusinkveld, Burkhard, Stahlmecke, Martin, Rosenbruch, Catrin, Albrecht, Roel P F, Schins

المصدر: Particle and fibre toxicology. 19(1)

مصطلحات موضوعية: Dietary Exposure, Mice, Inbred C57BL, Disease Models, Animal, Mice, Alzheimer Disease, Animals, Brain, Mice, Transgenic, Plaque, Amyloid, Silicon Dioxide, Nanostructures

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6856e2079a76cccdbf8f723aefc0d032
https://pubmed.ncbi.nlm.nih.gov/35337343

المؤلفون: Fatima den Ouden, Willem G. Schoonen, Emiel Rorije, Joop de Knecht, Edwin P. Zwart, Hennie M. Hodemaekers, Leo T.M. van der Ven, Renate M. Groot, Harm J. Heusinkveld

مصطلحات موضوعية: 0301 basic medicine, Adverse outcome pathways, Embryo, Nonmammalian, Carboxylic acid, Alkoxy alcohols, Carboxylic Acids, Developmental toxicity, Embryonic Development, Biology, Zebrafish embryos, Toxicology, Lethal Dose 50, 03 medical and health sciences, Acetic acid, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, Toxicity Tests, Gene expression, medicine, Animals, Zebrafish, Pharmacology, chemistry.chemical_classification, Valproic Acid, Ethanol, Gene Expression Regulation, Developmental, Embryo, Metabolism, Rats, 030104 developmental biology, Biochemistry, chemistry, 030220 oncology & carcinogenesis, Toxicity, Female, Fatty Alcohols, Hexanols, Water Pollutants, Chemical, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cc6788abb3fe6d8eeabac5f930497a
http://hdl.handle.net/10029/624957

المؤلفون: Mirjam, Luijten, Paul F K, Wackers, Emiel, Rorije, Jeroen L A, Pennings, Harm J, Heusinkveld

المصدر: Chemical research in toxicology. 34(2)

مصطلحات موضوعية: Databases, Factual, Dose-Response Relationship, Drug, Liver, Databases, Genetic, Hepatocytes, Animals, Chemical and Drug Induced Liver Injury, Organic Chemicals, Transcriptome, Risk Assessment, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6b4b0faa9cb3993707688c32b73c42f9
https://pubmed.ncbi.nlm.nih.gov/33378166

المؤلفون: Ruud A. Woutersen, Frédéric Schorsch, Marco Corvaro, Robin Gommans, Phil Botham, Gerrit Wolterink, Jan Willem van der Laan, Raffaella Corvi, Irene Manou, Federica Madia, Harm J. Heusinkveld, Jyotigna Mehta, Mirjam Luijten, Dick Lewis, Hedwig M. Braakhuis

مصطلحات موضوعية: Carcinogenesis, Carcinogenicity Tests, Computer science, Agrochemical, Mechanism based, 010501 environmental sciences, Toxicology, 01 natural sciences, Rodent carcinogenicity, hazard assessment, 03 medical and health sciences, mode of action, Neoplasms, carcinogenicity, Animals, Humans, Scientific debate, United States Environmental Protection Agency, Pesticides, Carcinogen, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, Weight of evidence, Mechanism (biology), business.industry, weight-of-evidence, risk assessment, United States, Nongenotoxic carcinogens, Risk analysis (engineering), Carcinogens, Agrochemicals, business, DNA Damage, rodent cancer bioassay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b440c09a4b5cd12a6f885f03ceb039c
http://hdl.handle.net/10029/624557

المؤلفون: Harm J. Heusinkveld, Tina Wahle, Roel P. F. Schins, Catrin Albrecht, Dirk Pijnenburg, Michail Dronov, Karsten Lamann, Burkhard Stahlmecke, Adriana Sofranko, Riet Hilhorst

المصدر: Neurotoxicology. 84

مصطلحات موضوعية: Male, medicine.medical_specialty, Neurobehavioural testing, Silver, Drug Evaluation, Preclinical, Metal Nanoparticles, Inflammation, Spleen, Toxicology, medicine.disease_cause, 28-day oral, Open field, 03 medical and health sciences, Mice, 0302 clinical medicine, Maschinenbau, TiO(2), Internal medicine, medicine, Toxicokinetics, Animals, Kinase activity, Protein kinase A, 030304 developmental biology, Peptide microarray, Titanium, 0303 health sciences, Chemistry, General Neuroscience, Neurotoxicity, Brain, Chemical Engineering, medicine.disease, Nanostructures, Mice, Inbred C57BL, Oxidative Stress, Endocrinology, medicine.anatomical_structure, Female, medicine.symptom, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84555ef045fba47412b7f7bd8030d66
https://pubmed.ncbi.nlm.nih.gov/33771574

المؤلفون: C. Veltman, Elena Menegola, L.T.M. van der Ven, Harm J. Heusinkveld, Mirjam Luijten

المصدر: Toxicology Letters. 350:S222

مصطلحات موضوعية: Process management, Workflow, business.industry, Adverse Outcome Pathway, Medicine, Relevance (information retrieval), General Medicine, Toxicology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::35f6167d2082968d66a021755269c49c
https://doi.org/10.1016/s0378-4274(21)00756-6