المؤلفون: Markel Martínez-Carranza, Léa Vialle, Clément Madru, Florence Cordier, Ayten Dizkirici Tekpinar, Ahmed Haouz, Pierre Legrand, Rémy A. Le Meur, Patrick England, Rémi Dulermo, J. Iñaki Guijarro, Ghislaine Henneke, Ludovic Sauguet

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/39beb4e1884341698268505f4146099f

المؤلفون: Puszko, Anna, Batista, Fernando, Ejjoummany, Abdelaziz, Bouillon, Anthony, Maurel, Manon, Adler, Pauline, Legru, Alice, Martinez, Mariano, Ortega Varga, Laura, Hadjadj, Margot, Alzari, Pedro Maria, Blondel, Arnaud, Haouz, Ahmed, Barale, Jean-Christophe, Hernandez, Jean-François

المساهمون: Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Bioinformatique structurale - Structural Bioinformatics, Cristallographie (Plateforme) - Crystallography (Platform), This work was supported by Institut Carnot Chimie Balard (FO-ICCB-M1-08 V01), AgenceNationale de la Recherche (ANR-19-CE18-0010-01, including fellowship to FB, PA, AKP,and AE). This project has also received funding from the European Union’s Horizon 2020research and innovation program under the Marie Sklodowska-Curie grant agreement SUBUNN° 898512 H2020-MSCA-IF-2019 (AKP). A. Bouillon and M. Martinez have been supportedby Agence Nationale pour la Recherche (ANR-11-RPIB-002)., We thank Mr Pierre Sanchez and the SynBio3 platform (IBMM, Montpellier, France) for mass spectrometry analyses. We thank the staff of the Crystallography core facility at the Institut Pasteur for carrying out robot-driven crystallization screenings. We acknowledge SOLEIL for provision of synchrotron radiation facilities and we thank the staff of the Proxima-2 beamline for support during data collection. We are grateful to the healthy volunteers for their contribution to the study and thank the staff, particularly Hélène Laude and Emmanuel Roux, of ICAReB-Clin and ICAReB-biobank of the CRBIP (BioResource Center) from the Medical Direction at Institut Pasteur for managing the visits of healthy volunteers and for preparing and providing the human blood samples used to cultivate P. falciparum, ANR-19-CE18-0010,SPIM,Synthèse, biologie et structure pour guider l'optimisation d'Inhibiteurs de la peptidase SUB1 de Plasmodium, une cible potentielle pour le traitement du paludisme(2019), ANR-11-RPIB-0002,MaPI,Développement d'un composé "leader" à l'origine d'une nouvelle génération d'anti-paludiques: une approche multi-cibles(2011), European Project: 898512 ,H2020-MSCA-IF-2019 ,10.3030/898512,SUBUN(2020)

المصدر: ISSN: 1860-7179.

مصطلحات موضوعية: Malaria, SUB1 inhibitors, alpha-ketoamides, Peptides, Structure-activity relationships, [CHIM]Chemical Sciences, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/39832214; info:eu-repo/grantAgreement//898512 /EU/Engineering substrate-based inhibitors of Plasmodium SUB1, a potential target for Malaria treatment./SUBUN; PUBMED: 39832214

الاتاحة: https://hal.science/hal-04903039
https://hal.science/hal-04903039v1/document
https://hal.science/hal-04903039v1/file/ChemMedChem%20-%202025%20-%20Puszko%20-%20Towards%20Improved%20Peptidic%20%E2%80%90Ketoamide%20Inhibitors%20of%20the%20Plasmodial%20Subtilisin%E2%80%90Like%20SUB1%20.pdf
https://doi.org/10.1002/cmdc.202400924

المؤلفون: Cyril Planchais, Ignacio Fernández, Benjamin Chalopin, Timothée Bruel, Pierre Rosenbaum, Maxime Beretta, Jordan D. Dimitrov, Laurine Conquet, Flora Donati, Matthieu Prot, Françoise Porrot, Delphine Planas, Isabelle Staropoli, Florence Guivel-Benhassine, Eduard Baquero, Sylvie van der Werf, Ahmed Haouz, Etienne Simon-Lorière, Xavier Montagutelli, Bernard Maillère, Félix A. Rey, Pablo Guardado-Calvo, Hervé Nozach, Olivier Schwartz, Hugo Mouquet

المصدر: iScience, Vol 27, Iss 7, Pp 110354- (2024)

مصطلحات موضوعية: immunology, virology, Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224015797; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/c653ff8957ad4f029dc47c33231f0107

المؤلفون: Gaday, Quentin, Megrian, Daniela, Carloni, Giacomo, Martinez, Mariano, Sokolova, Bohdana, Assaya, Mathilde Ben, Legrand, Pierre, Brûlé, Sebastien, Haouz, Ahmed, Wehenkel, Anne Marie, Alzari, Pedro M.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2022 Dec . 119(50), 1-10.

URL الوصول: https://www.jstor.org/stable/27207348

المؤلفون: Mariano Martinez, Anthony Bouillon, Sébastien Brûlé, Bertrand Raynal, Ahmed Haouz, Pedro M. Alzari, Jean-Christophe Barale

المصدر: mBio, Vol 15, Iss 3 (2024)

مصطلحات موضوعية: malaria, Plasmodium, subtilin-like protease, pro-domain, enzyme regulation, 3D structure, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/ba0f32637eef4326823e45be733aa725

المؤلفون: Dioury, Fabienne, San, Carine, Gnanalingam, Gayathiri, Henoumont, Céline, Rousselin, Yoann, Haouz, Ahmed, Shepard, William, Hosten, Benoît, Vijayakumar, Kamsana, Laurent, Sophie, Port, Marc

المساهمون: Laboratoire Génomique, bioinformatique et chimie moléculaire (GBCM), Conservatoire National des Arts et Métiers CNAM (CNAM), Hopital Saint-Louis AP-HP (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), NMR Laboratory, Université de Mons, Université de Mons / University of Mons (UMONS), Université de Bourgogne (UB), Institut de Chimie Moléculaire de l'Université de Bourgogne Dijon (ICMUB), Université de Bourgogne (UB)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Pôle Chimie Moléculaire Dijon (PACSMUB), Université de Bourgogne (UB)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Bourgogne (UB)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Société d’Accélération du Transfert de Technologie (SATT) Grand Est - Welience, Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S 1144 / U1144)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), La Ligue contre le Cancer, Aviesan ITMO Cancer -Inserm

المصدر: ISSN: 0947-6539.

مصطلحات موضوعية: Fluorine-18, Gallium complexes, Positron Emission Tomography PET, Macrocyclic ligands, Radiochemistry, [CHIM]Chemical Sciences

Relation: info:eu-repo/semantics/altIdentifier/pmid/39331479; PUBMED: 39331479; PUBMEDCENTRAL: PMC11618045

الاتاحة: https://hal.science/hal-04826589
https://hal.science/hal-04826589v1/document
https://hal.science/hal-04826589v1/file/Chemistry%20A%20European%20J%20-%202024%20-%20Dioury%20-%20Bifunctional%20Hexadentate%20Pyclen%20Based%20Chelating%20Agent%20for%20Mild%20Radiofluorination.pdf
https://doi.org/10.1002/chem.202403358

المؤلفون: Dejoux, Alice, Zhu, Qianqian, Ganneau, Christelle, Goff, Odile Richard-Le, Godon, Ophélie, Lemaitre, Julien, Relouzat, Francis, Huetz, François, Sokal, Aurélien, Vandenberghe, Alexis, Pecalvel, Cyprien, Hunault, Lise, Derenne, Thomas, Gillis, Caitlin, Iannascoli, Bruno, Wang, Yidan, Rose, Thierry, Mertens, Christel, Nicaise-Roland, Pascale, England, Patrick, Mahévas, Matthieu, de Chaisemartin, Luc, Le Grand, Roger, Letscher, Hélène, Saul, Frederick, Pissis, Cédric, Haouz, Ahmed, Reber, Laurent, L, Chappert, Pascal, Jönsson, Friederike, Ebo, Didier, G, Millot, Gaël, A, Bay, Sylvie, Chollet-Martin, Sylvie, Gouel-Chéron, Aurélie, Bruhns, Pierre, Mancardi, David, Granger, Vanessa, Longrois, Dan, Montravers, Philippe, Sauvan, Caroline, Aubier, Michel, Neukirch, Catherine, Dib, Fadia, Paugam-Burtz, Catherine, Necib, Skander, Keita-Meyer, Hawa, Faitot, Valentina, Mebazaa, Alexandre, Le Dorze, Matthieu, Cholley, Bernard, Mantz, Jean, Langeron, Olivier, Roche, Sabrine, Jacob, Laurent, Plaud, Benoit, Bresson, Julie, Chahine, Carole, Fischler, Marc, Guinnepain, Marie-Thérèse, Tubach, Florence, Mignon, Antoine

المساهمون: Anticorps en thérapie et pathologie - Antibodies in Therapy and Pathology, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Collège Doctoral, Sorbonne Université (SU), Inflammation, microbiome, immunosurveillance (MI2), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Chimie des Biomolécules - Chemistry of Biomolecules, Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris-Saclay, Institut National de la Santé et de la Recherche Médicale (INSERM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Center for Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin Bicêtre, Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Service de médecine interne, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Beaujon AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Biologie Cellulaire des Lymphocytes - Lymphocyte Cell Biology, Equipe labellisée Ligue contre le Cancer, Antwerp University Hospital Edegem (UZA), University of Antwerp (UA), AZ Jan Palfijn Hospital Ghent, Belgium, AP-HP - Hôpital Bichat - Claude Bernard Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Biophysique Moléculaire (plateforme) - Molecular Biophysics (platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Cristallographie (Plateforme) - Crystallography (Platform), Centre National de la Recherche Scientifique (CNRS), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Physiopathologie et Epidémiologie des Maladies Respiratoires (PHERE (UMR_S_1152 / U1152)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Laboratoire d'excellence Inflamex site Bichat, Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Work in the Bruhns lab was supported by the Institut Pasteur, Institut National de la Santé et de la Recherche Médicale (Inserm), Fondation pour la Recherche Médicale, Paris, France (Programme Equipe FRM grant EQU202203014631 to P.B.), Accélérateur de l’innovation de l’Institut Pasteur (grant rocuCEPT), Agence Nationale de la Recherche (ANR grant ANR-21-CE15-0027), and European Research Council (ERC)–Seventh Framework Program (ERC-2013-CoG 616050). Data partially resulted from the work performed in the International Research Program IRP “ALLERGYMINE” (Inserm grant call 2022-2026) to P.B. A.D. and L.H. were doctoral fellows of Sorbonne Université. A.D. was partly supported by a fellowship from the Fondation pour la Recherche Médicale grant FDT202304016860. Q.Z. received a PhD scholarship from the Chinese Science Council. A.G.-C. was a recipient of a poste d’accueil 2017 Institut Pasteur–Assistance Publique des Hôpitaux de Paris (APHP) and from a grant provided by INSERM, SFAR (Société Française d’Anesthésie et de Réanimation), and SRLF (Société de Réanimation de Langue Française) through the Bourse de Recherche du Comité d’interface INSERM-SFAR-SRLF 2012. C.M.G. was supported partly by a stipend from the Pasteur-Paris University (PPU) International PhD program and by the Institut Carnot Pasteur Maladies Infectieuses. P.B. benefited from additional support from AP-HP through a “Contrat Local d’Interface 2014” and the “Département Hospitalo-Universitaire” (DHU) FIRE. The sponsor of the NASA study was the Direction de la Recherche Clinique et de l’Innovation de l’AP-HP (France)., ANR-21-CE15-0027,CURAREP,Identification de répertoires d'anticorps humains dans l'hypersensibilité aux curares pour de nouvelles solutions diagnostiques et thérapeutiques(2021), European Project: 616050,EC:FP7:ERC,ERC-2013-CoG,MYELOSHOCK(2014)

المصدر: ISSN: 1946-6234.

مصطلحات موضوعية: allergy, perioperative anaphylaxis, therapeutics, antibody repertoires, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology

Relation: info:eu-repo/semantics/altIdentifier/pmid/39259810; info:eu-repo/grantAgreement/EC/FP7/616050/EU/Role of myeloid cells, their mediators and their antibody receptors in allergic shock (anaphylaxis) using humanized mouse models and clinical samples/MYELOSHOCK; PUBMED: 39259810

الاتاحة: https://pasteur.hal.science/pasteur-04706288
https://pasteur.hal.science/pasteur-04706288v1/document
https://pasteur.hal.science/pasteur-04706288v1/file/Combined_pdf_no_marks.pdf
https://doi.org/10.1126/scitranslmed.ado4463

المؤلفون: Legru, Alice, Batista, Fernando, Puszko, Anna, Bouillon, Anthony, Maurel, Manon, Martinez, Mariano, Ejjoummany, Abdelaziz, Ortega Varga, Laura, Adler, Pauline, Mechaly, Ariel, E, Hadjadj, Margot, Sosnowski, Piotr, Hopfgartner, Gérard, Alzari, Pedro, M., Blondel, Arnaud, Haouz, Ahmed, Barale, Jean-Christophe, Hernandez, Jean-François

المساهمون: Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Microbiologie structurale - Structural Microbiology (Microb. Struc. (UMR_3528 / U-Pasteur_5)), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Bioinformatique structurale - Structural Bioinformatics, Cristallographie (Plateforme) - Crystallography (Platform), Université de Genève = University of Geneva (UNIGE), This work was supported by Institut Carnot Chimie Balard (FO-ICCB-M1-08 V01), Agence Nationale de la Recherche (ANR-19-CE18-0010-01, including fellowship to FB, PA, AKP, LOV and AE). This project has also received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement SUBUN N◦ 898512 H2020-MSCA-IF-2019 (AKP). A. Bouillon and M. Martinez have been supported by Agence Nationale pour la Recherche (ANR-11-RPIB-002). LOV has also been supported by Agence Nationale pour la Recherche (ANR-17-CE11-0030) and by the “URGENCE COVID-19” fundraising campaign of Institut Pasteur., We thank Mr Pierre Sanchez (IBMM, Montpellier, France) for mass spectrometry analyses. We thank the staff of the Crystallography core facility at the Institut Pasteur for carrying out robot-driven crystalliza- tion screenings. We acknowledge ESRF and SOLEIL for provision of synchrotron radiation facilities and we thank the staffs of the ID29, ID30 and Proxima-1 beamlines for support during data collection. We are grateful to the healthy volunteers for their contribution to the study and thank the staff, particularly H´el`ene Laude, Blanca Liliana Perlaza, Emmanuel Roux, Dorian Cheval, Linda Sangari and Sophie Vacant of ICAReB-Clin and ICAReB-biobank of the CRBIP (BioResource Center) from the Medical Direction at Institut Pasteur for managing the visits of healthy volunteers and for preparing and providing the human blood samples used to cultivate P. falciparum., ANR-17-CE11-0030,NICOFIVE,Découverte de modulateurs allostériques ciblant les récepteurs nicotiniques alpha5(2017), ANR-19-CE18-0010,SPIM,Synthèse, biologie et structure pour guider l'optimisation d'Inhibiteurs de la peptidase SUB1 de Plasmodium, une cible potentielle pour le traitement du paludisme(2019), ANR-11-RPIB-0002,MaPI,Développement d'un composé "leader" à l'origine d'une nouvelle génération d'anti-paludiques: une approche multi-cibles(2011)

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Structure activity relationships, Malaria, SAR, crystal structures, SUB1 inhibitors, Pseudopeptides, a-ketoamides, [SDV]Life Sciences [q-bio], [CHIM]Chemical Sciences

Relation: info:eu-repo/semantics/altIdentifier/pmid/38503166; PUBMED: 38503166

الاتاحة: https://hal.science/hal-04727940
https://hal.science/hal-04727940v1/document
https://hal.science/hal-04727940v1/file/Legru-Batista_Manuscrit_R.pdf
https://doi.org/10.1016/j.ejmech.2024.116308

المؤلفون: Voegele, A, Sadi, M, O'Brien, DP, Gehan, P, Raoux-Barbot, D, Davi, M, Hoos, S, Brûlé, S, Raynal, B, Weber, P, Mechaly, A, Haouz, A, Rodriguez, N, Vachette, P, Durand, D, Brier, S, Ladant, D, Chenal, A

Relation: https://ora.ox.ac.uk/objects/uuid:72615147-d6b6-4cf2-9b5b-47aa91f6be7a; https://doi.org/10.1002/advs.202003630

الاتاحة: https://doi.org/10.1002/advs.202003630
https://ora.ox.ac.uk/objects/uuid:72615147-d6b6-4cf2-9b5b-47aa91f6be7a

المؤلفون: Le Coadou, Louise, Berthelet, Jérémy, Mechaly, Ariel E., Michail, Christina, Bui, Linh-Chi, Dairou, Julien, Haouz, Ahmed, Dupret, Jean-Marie, Rodrigues Lima, Fernando

المساهمون: Université de Paris, ANR, Institut Pasteur, Centre National de la Recherche Scientifique

المصدر: Biochemical and Biophysical Research Communications ; volume 695, page 149400 ; ISSN 0006-291X

الاتاحة: http://dx.doi.org/10.1016/j.bbrc.2023.149400
https://api.elsevier.com/content/article/PII:S0006291X23014948?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006291X23014948?httpAccept=text/plain

المؤلفون: Clément Madru, Markel Martínez-Carranza, Sébastien Laurent, Alessandra C. Alberti, Maelenn Chevreuil, Bertrand Raynal, Ahmed Haouz, Rémy A. Le Meur, Marc Delarue, Ghislaine Henneke, Didier Flament, Mart Krupovic, Pierre Legrand, Ludovic Sauguet

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8ae48732a3044f69b9e87147a45794c9

المؤلفون: Ignacio Fernández, Lasse Toftdal Dynesen, Youna Coquin, Riccardo Pederzoli, Delphine Brun, Ahmed Haouz, Antoine Gessain, Félix A. Rey, Florence Buseyne, Marija Backovic

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/3ad03332c7764f46a5fdf2481a22cfcc

المؤلفون: Christian Klug, Michael Coates, Linda Frey, Merle Greif, Melina Jobbins, Alexander Pohle, Abdelouahed Lagnaoui, Wahiba Bel Haouz, Michal Ginter

المصدر: Swiss Journal of Palaeontology, Vol 142, Iss 1, Pp 1-28 (2023)

مصطلحات موضوعية: Fossil man. Human paleontology, GN282-286.7, Paleontology, QE701-760

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1664-2376; https://doaj.org/toc/1664-2384

URL الوصول: https://doaj.org/article/f5440f43b70244f396554dada869593f

المؤلفون: E. Crampon, E. Covernton, M. C. Vaney, M. Dellarole, S. Sommer, A. Sharma, A. Haouz, P. England, J. Lepault, S. Duquerroy, F. A. Rey, G. Barba-Spaeth

المصدر: mBio, Vol 14, Iss 5 (2023)

مصطلحات موضوعية: flavivirus maturation, X-ray crystallography, viral fusion, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/b5ca6c538fc84d2080215b04285e4a10

المؤلفون: Vernuccio, Riccardo, Martínez León, Alejandro, Poojari, Chetan, Buchrieser, Julian, Selverian, Christopher, Jaleta, Yakin, Meola, Annalisa, Guivel-Benhassine, Florence, Porrot, Françoise, Haouz, Ahmed, Chevreuil, Maelen, Raynal, Bertrand, Mercer, Jason, Simon-Loriere, Etienne, Chandran, Karti, Schwartz, Olivier, Hub, Jochen S., Guardado-Calvo, Pablo

مصطلحات موضوعية: Virology, Biophysics

Relation: https://doi.org/10.21203/rs.3.rs-5002222/v1; https://doi.org/10.5281/zenodo.13698534; https://doi.org/10.5281/zenodo.14096216; oai:zenodo.org:14096216

الاتاحة: https://doi.org/10.5281/zenodo.14096216

المؤلفون: Martínez-Carranza, Markel, Vialle, Léa, Madru, Clément, Cordier, Florence, Tekpinar, Ayten, Dizkirici, Haouz, Ahmed, Legrand, Pierre, Le Meur, Rémy, A, England, Patrick, Dulermo, Rémi, Guijarro, J. I., Henneke, Ghislaine, Sauguet, Ludovic

المساهمون: Architecture et Dynamique des Macromolécules Biologiques - Architecture and Dynamics of Biological Macromolecules, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Biologie et Ecologie des Ecosystèmes Marins Profonds (BEEP), Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS), Plateforme Technologique de RMN Biologique et HDX-MS - Biological NMR and HDX-MS Technological Platform, Bioinformatique structurale - Structural Bioinformatics, Cristallographie (Plateforme) - Crystallography (Platform), Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Biophysique Moléculaire (plateforme) - Molecular Biophysics (platform), We gratefully acknowledge the financial support of ANR (Grant ARCHAPRIM). C.M. was funded by a postdoctoral Pasteur-Roux-Cantarini fellowship. M.M.C. was funded by apostdoctoral FRM fellowship (Fondation pour la Recherche Médicale). A.D.T. was founded by a Pause grant from Collège de France. We wish to acknowledge SOLEIL for the provision of synchrotron radiation facilities and the staff of beamlines PROXIMA-1 and PROXIMA-2 (Saint-Aubin, France). We would like to thank the staff of the Nanoimaging Core Facility at Institut Pasteur for cryo-EM instrument access for the preliminary cryo-EM datasets. Electron microscopy instrument time was provided through the OPIC electron microscopy facility, a UK Instruct-ERIC Centre, which was founded by a Wellcome JIF award (060208/Z/00/Z) and is supported by a Wellcome equipment grant (093305/Z/10/Z). Cryo-EM final data collection experiments were funded by UK Instruct-ERIC, PID: 21658. The 800-MHz NMR spectrometer of the Institut Pasteur was partially funded by the Région Ile de France (SESAME 2014 NMRCHR grant no 4014526)., ANR-20-CE11-0003,ARCHAPRIM,L'ADN primase, le couteau Suisse des Archées: Etude de biologie intégrative(2020)

المصدر: https://hal.science/hal-04728470 ; 2024.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

Relation: BIORXIV: 2024.04.29.591592

الاتاحة: https://hal.science/hal-04728470
https://hal.science/hal-04728470v1/document
https://hal.science/hal-04728470v1/file/2024.04.29.591592v1.full.pdf
https://doi.org/10.1101/2024.04.29.591592

المؤلفون: Karlsson, Emelia, Andén, Olivia, Fan, Chen, Fourati, Zaineb, Haouz, Ahmed, Zhuang, Yuxuan, Howard, Rebecca, J, Delarue, Marc, Lindahl, Erik

المساهمون: Stockholm University, KTH Royal Institute of Technology Stockholm (KTH), Cibles Thérapeutiques et conception de médicaments (CiTCoM - UMR 8038), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Cristallographie (Plateforme) - Crystallography (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Architecture et Dynamique des Macromolécules Biologiques - Architecture and Dynamics of Biological Macromolecules

المصدر: https://pasteur.hal.science/pasteur-04769523 ; 2024.

مصطلحات موضوعية: sTeLIC, allosteric modulation, druggable cavity, ligand-gated ion channel, electrophysiology, cryo-EM, X-ray crystallography, [SDV]Life Sciences [q-bio]

Relation: BIORXIV: 2024.05.02.592243

الاتاحة: https://pasteur.hal.science/pasteur-04769523
https://pasteur.hal.science/pasteur-04769523v1/document
https://pasteur.hal.science/pasteur-04769523v1/file/2024.05.02.592243v1.full.pdf
https://doi.org/10.1101/2024.05.02.592243

المؤلفون: Nourisson, Antonin, Missoury, Sophia, Haouz, Ahmed, Delarue, Marc

المساهمون: Architecture et Dynamique des Macromolécules Biologiques - Architecture and Dynamics of Biological Macromolecules, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Ecole Doctorale Complexité du Vivant (ED515), Sorbonne Université (SU), Cristallographie (Plateforme) - Crystallography (Platform), This work was supported by Sorbonne Université which funded AN’s PhD thesis, and the Fondation pour la Recherche Médicale, grant number DT202304016786, for a 6-month extension of the PhD thesis, We thank the Molecular Biophysics and Macromolecular Interactions Platform and the654 Proteomics Platform at Institut Pasteur for help in characterizing the purified proteins by655 mass spectrometry. We thank the Crystallogenesis and Crystallography Platform (PFX) of656 Institut Pasteur for help in crystallization and crystallographic data collection.

المصدر: https://pasteur.hal.science/pasteur-04769537 ; 2024.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

Relation: BIORXIV: 2024.07.26.605286

الاتاحة: https://pasteur.hal.science/pasteur-04769537
https://pasteur.hal.science/pasteur-04769537v1/document
https://pasteur.hal.science/pasteur-04769537v1/file/2024.07.26.605286v1.full.pdf
https://doi.org/10.1101/2024.07.26.605286

المؤلفون: Corentin Léger, Irène Pitard, Mirko Sadi, Nicolas Carvalho, Sébastien Brier, Ariel Mechaly, Dorothée Raoux-Barbot, Maryline Davi, Sylviane Hoos, Patrick Weber, Patrice Vachette, Dominique Durand, Ahmed Haouz, J. Iñaki Guijarro, Daniel Ladant, Alexandre Chenal

المصدر: BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)

مصطلحات موضوعية: Calmodulin, CaM, Calmidazolium, CDZ, Calmodulin antagonist, Structure, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1741-7007

URL الوصول: https://doaj.org/article/e17ab00d471042d985086711d9d6706a

المؤلفون: Dioury, Fabienne, San, Carine, Gnanalingam, Gayathiri, Henoumont, Céline, Rousselin, Yoann, Haouz, Ahmed, Shepard, William, Hosten, Benoît, Vijayakumar, Kamsana, Laurent, Sophie, Port, Marc

المصدر: Chemistry - A European Journal; 12/5/2024, Vol. 30 Issue 68, p1-15, 15p

مصطلحات موضوعية: POSITRON emission tomography, CHELATES, TECHNOLOGICAL innovations, TUMOR diagnosis, AQUEOUS solutions