المؤلفون: Hansen, Tobias N., Danková, Daniela, Bæk, Michael, Grlaš, Linda, Olsen, Christian A.

المصدر: Hansen , T N , Danková , D , Bæk , M , Grlaš , L & Olsen , C A 2024 , ' Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays : Discovery of Histone Deacetylase Inhibitors ' , JACS Au , vol. 4 , no. 5 , pp. 1854–1862 . https://doi.org/10.1021/jacsau.4c00042

مصطلحات موضوعية: epigenetics, HDAC inhibitors, library synthesis, solid-phase synthesis, SuFEx

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/sulfurvi-fluoride-exchange-chemistry-in-solidphase-synthesis-of-compound-arrays(a7aa7639-f73f-49b9-8b8e-bcf008353c2f).html
https://doi.org/10.1021/jacsau.4c00042
https://curis.ku.dk/ws/files/392982226/hansen_et_al_2024_sulfur_vi_fluoride_exchange_chemistry_in_solid_phase_synthesis_of_compound_arrays_discovery_of.pdf

المؤلفون: Hansen, Tobias N., San Segundo, Marcos, Mergel, Annika M., Olsen, Christian Adam

المساهمون: Novo Nordisk Fonden, Villum Fonden

الاتاحة: https://doi.org/10.26434/chemrxiv-2024-bncb0-v2
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/677d609881d2151a0239b4d4/original/advances-in-sulfur-fluoride-exchange-for-chemical-biology.pdf

المؤلفون: Bolding, Julie E., Nielsen, Alexander L., Jensen, Iben, Hansen, Tobias N., Ryberg, Line A., Jameson, Samuel T., Harris, Pernille, Peters, Günther H. J., Denu, John M., Rogers, Joseph M., Olsen, Christian A.

المصدر: Bolding , J E , Nielsen , A L , Jensen , I , Hansen , T N , Ryberg , L A , Jameson , S T , Harris , P , Peters , G H J , Denu , J M , Rogers , J M & Olsen , C A 2023 , ' Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7 ' , Angewandte Chemie International Edition , vol. 62 , e20231459 . https://doi.org/10.1002/anie.202314597

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/2c8bfd65-008d-48de-a731-709411249ca3

الاتاحة: https://orbit.dtu.dk/en/publications/2c8bfd65-008d-48de-a731-709411249ca3
https://doi.org/10.1002/anie.202314597
https://backend.orbit.dtu.dk/ws/files/344711366/Angew_Chem_Int_Ed_-_2023_-_Bolding_-_Substrates_and_Cyclic_Peptide_Inhibitors_of_the_Oligonucleotide_Activated_Sirtuin_7.pdf

المؤلفون: Bolding, Julie E., Martín-Gago, Pablo, Rajabi, Nima, Gamon, Luke F., Hansen, Tobias N., Bartling, Christian R.O., Strømgaard, Kristian, Davies, Michael J., Olsen, Christian A.

المصدر: Bolding , J E , Martín-Gago , P , Rajabi , N , Gamon , L F , Hansen , T N , Bartling , C R O , Strømgaard , K , Davies , M J & Olsen , C A 2022 , ' Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase** ' , Angewandte Chemie - International Edition , vol. 61 , no. 47 , e202204565 . https://doi.org/10.1002/anie.202204565

مصطلحات موضوعية: Covalent Inhibition, Enzyme Inhibitors, SIRT5, Sirtuins, SuFEx

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/aryl-fluorosulfate-based-inhibitors-that-covalently-target-the-sirt5-lysine-deacylase(f137f075-3a39-4c1d-8750-d49c1ab90873).html
https://doi.org/10.1002/anie.202204565
https://curis.ku.dk/ws/files/328441125/Angew_Chem_Int_Ed_2022_Bolding_Aryl_Fluorosulfate_Based_Inhibitors_That_Covalently_Target_the_SIRT5_Lysine_Deacylase.pdf

المؤلفون: Rajabi, Nima, Hansen, Tobias N., Nielsen, Alexander L., Nguyen, Huy T., Bæk, Michael, Bolding, Julie E., Bahlke, Oskar, Petersen, Sylvester E.G., Bartling, Christian R.O., Strømgaard, Kristian, Olsen, Christian A.

المصدر: Rajabi , N , Hansen , T N , Nielsen , A L , Nguyen , H T , Bæk , M , Bolding , J E , Bahlke , O , Petersen , S E G , Bartling , C R O , Strømgaard , K & Olsen , C A 2022 , ' Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme** ' , Angewandte Chemie - International Edition , vol. 61 , no. 22 , e202115805 . https://doi.org/10.1002/anie.202115805

مصطلحات موضوعية: Bioisosteres, Enzyme Inhibitors, Prodrugs, SIRT5, Sirtuins

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/investigation-of-carboxylic-acid-isosteres-and-prodrugs-for-inhibition-of-the-human-sirt5-lysine-deacylase-enzyme(30614323-0e9e-4a4a-a1f4-3ac1d53aea94).html
https://doi.org/10.1002/anie.202115805
https://curis.ku.dk/ws/files/308041103/Angew_Chem_Int_Ed_2022_Rajabi_Investigation_of_Carboxylic_Acid_Isosteres_and_Prodrugs_for_Inhibition_of_the_Human.pdf

المؤلفون: Smit, Florent X., van der Velden, Wijnand J.C., Kizilkaya, Hüsün S., Nørskov, Amalie, Lückmann, Michael, Hansen, Tobias N., Sparre-Ulrich, Alexander H., Qvotrup, Katrine, Frimurer, Thomas M., Rosenkilde, Mette M.

المساهمون: Carlsbergfondet, Novo Nordisk Foundation

المصدر: Structure ; volume 29, issue 7, page 679-693.e6 ; ISSN 0969-2126

الاتاحة: http://dx.doi.org/10.1016/j.str.2021.04.001
https://api.elsevier.com/content/article/PII:S0969212621001179?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0969212621001179?httpAccept=text/plain

المؤلفون: Hansen, Tobias N., San Segundo, Marcos, Mergel, Annika M., Olsen, Christian Adam

المساهمون: Novo Nordisk Fonden, Villum Fonden

الاتاحة: https://doi.org/10.26434/chemrxiv-2024-bncb0
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/6750429f5a82cea2faf2e786/original/advances-in-sulfur-fluoride-exchange-for-chemical-biology.pdf

المؤلفون: Hansen, Tobias N., Dankova, Daniela, Bæk, Michael, Grlas, Linda, Olsen, Christian Adam

الاتاحة: http://dx.doi.org/10.26434/chemrxiv-2024-j0wmd
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/65c4de3866c138172937a0a9/original/sulfur-vi-fluoride-exchange-chemistry-in-solid-phase-synthesis-of-compound-arrays-discovery-of-histone-deacetylase-inhibitors.pdf

المؤلفون: Hansen, Tobias N.¹ (AUTHOR), Olsen, Christian A.¹ (AUTHOR) cao@sund.ku.dk

المصدر: Chemistry - A European Journal. 2/12/2024, Vol. 30 Issue 9, p1-14. 14p.

مصطلحات موضوعية: *THIOAMIDES, *BIOACTIVE compounds, *PEPTIDES, *HYDROLASES, *PROTEIN folding, *HYDROGEN bonding

المؤلفون: Hansen, Tobias N., Olsen, Christian Adam

الاتاحة: http://dx.doi.org/10.26434/chemrxiv-2023-g00sf
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/657714c9fd283d7904c29012/original/contemporary-applications-of-thioamides-and-methods-for-their-synthesis.pdf

المؤلفون: Hansen, Tobias N.¹ (AUTHOR), Yuan, Xinyi¹ (AUTHOR), I Santana, Marc S.¹ (AUTHOR), Olsen, Christian A.¹ (AUTHOR)

المصدر: Bioorganic & Medicinal Chemistry Letters. Jan2025, Vol. 115, pN.PAG-N.PAG. 1p.

مصطلحات موضوعية: *POST-translational modification, *DICARBOXYLIC acids, *ENZYME kinetics, *ENZYME inhibitors, *BREAST cancer

المؤلفون: Smit, Florent X., van der Velden, Wijnand J. C., Kizilkaya, Husun S., Nørskov, Amalie, Lückmann, Michael, Hansen, Tobias N., Sparre-Ulrich, Alexander H., Qvotrup, Katrine, Frimurer, Thomas M., Rosenkilde, Mette M.

المصدر: Smit , F X , van der Velden , W J C , Kizilkaya , H S , Nørskov , A , Lückmann , M , Hansen , T N , Sparre-Ulrich , A H , Qvotrup , K , Frimurer , T M & Rosenkilde , M M 2021 , ' Investigating GIPR (ant)agonism : A structural analysis of GIP and its receptor ' , Structure , vol. 29 , no. 7 , pp. 679-693.e6 .

مصطلحات الفهرس: GASTRIC-INHIBITORY POLYPEPTIDE, DEPENDENT INSULINOTROPIC POLYPEPTIDE, GLP-1 RECEPTOR, GLUCOSE, DYNAMICS, GLUCAGON, FAMILY, FRAGMENT, LESSONS, COMPLEX, article

URL: https://curis.ku.dk/portal/da/publications/investigating-gipr-antagonism(051b4538-3aa1-4c4d-ac35-b88c3220d468).html
https://doi.org/10.1016/j.str.2021.04.001

المؤلفون: Rajabi, Nima, Nielsen, Alexander L., Hansen, Tobias N., Nguyen, Huy T., Bæk, Michael, Bolding, Julie E., Bahlke, Oskar Ø., Petersen, Sylvester E. G., Bartling, Christian R. O., Strømgaard, Kristian, Olsen, Christian Adam

المساهمون: Novo Nordisk Fonden, Carlsbergfondet, European Research Council

الاتاحة: http://dx.doi.org/10.26434/chemrxiv-2021-29rtf
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/619d4c79a129236d6c4bcb9f/original/investigation-of-carboxylic-acid-isosteres-for-inhibition-of-the-human-sirt5-lysine-deacylase-enzyme.pdf

المؤلفون: Paerl, Ryan William, Hansen, Tobias N. G., Henriksen, Nathalie N. S. E., Olesen, Asmus K., Riemann, Lasse

المصدر: Paerl , R W , Hansen , T N G , Henriksen , N N S E , Olesen , A K & Riemann , L 2018 , ' N-fixation and related O 2 constraints on model marine diazotroph Pseudomonas stutzeri BAL361 ' , Aquatic Microbial Ecology , vol. 81 , no. 2 , pp. 125-136 . https://doi.org/10.3354/ame01867

الاتاحة: https://curis.ku.dk/portal/da/publications/nfixation-and-related-o2-constraints-on-model-marine-diazotroph-pseudomonas-stutzeri-bal361(b4ec251d-9619-4986-8936-7516cb3210d7).html
https://doi.org/10.3354/ame01867

المؤلفون: Paerl, Ryan William, Hansen, Tobias N. G., Henriksen, Nathalie N. S. E., Olesen, Asmus K., Riemann, Lasse

المصدر: Paerl , R W , Hansen , T N G , Henriksen , N N S E , Olesen , A K & Riemann , L 2018 , ' N-fixation and related O 2 constraints on model marine diazotroph Pseudomonas stutzeri BAL361 ' , Aquatic Microbial Ecology , vol. 81 , no. 2 , pp. 125-136 .

مصطلحات الفهرس: article

URL: https://curis.ku.dk/portal/da/publications/nfixation-and-related-o2-constraints-on-model-marine-diazotroph-pseudomonas-stutzeri-bal361(b4ec251d-9619-4986-8936-7516cb3210d7).html
https://doi.org/10.3354/ame01867