المؤلفون: Smith, Alasdair, Wall, Richard, Patterson, Stephen, Rowan, Tim, Rico Vidal, Eva, Stojanovski, Laste, Huggett, Margaret, Hampton, Shahienaz, Thomas, Michael G., Corpas Lopez, Victoriano, Gillingwater, Kirsten, Duke, Jeff, Napier, Grant, Peter, Rosemary, Vitouley, Hervé S., Harrison, Justin, Milne, Rachel, Jeacock, Laura, Baker, Nicola, Davis, Susan, Simeons, Frederick, Riley, Jennifer, Horn, David, Brun, Reto, Zuccotto, Fabio, Witty, Michael J., Wyllie, Susan, Read, Kevin D., Gilbert, Ian H.

المصدر: Smith , A , Wall , R , Patterson , S , Rowan , T , Rico Vidal , E , Stojanovski , L , Huggett , M , Hampton , S , Thomas , M G , Corpas Lopez , V , Gillingwater , K , Duke , J , Napier , G , Peter , R , Vitouley , H S , Harrison , J , Milne , R , Jeacock , L , Baker , N , Davis , S , Simeons , F , Riley , J , Horn , D , Brun , R ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/02646016-eb14-47c6-bf41-8c19913b3e44

الاتاحة: https://discovery.dundee.ac.uk/en/publications/02646016-eb14-47c6-bf41-8c19913b3e44
https://doi.org/10.1021/acs.jmedchem.1c02104
https://discovery.dundee.ac.uk/ws/files/72960762/acs.jmedchem.1c02104.pdf
https://discovery.dundee.ac.uk/ws/files/71878037/Supporting_Information_V36.pdf
http://www.scopus.com/inward/record.url?scp=85127364726&partnerID=8YFLogxK

المؤلفون: Harrison, Justin R., Sarkar, Sandipan, Hampton, Shahienaz, Riley, Jennifer, Stojanovski, Laste, Sahlberg, Christer, Appelqvist, Pia, Erath, Jessey, Mathan, Vinodhini, Rodriguez, Ana, Kaiser, Marcel, Pacanowska, Dolores Gonzalez, Read, Kevin D., Johansson, Nils Gunnar, Gilbert, Ian H.

المصدر: Harrison , J R , Sarkar , S , Hampton , S , Riley , J , Stojanovski , L , Sahlberg , C , Appelqvist , P , Erath , J , Mathan , V , Rodriguez , A , Kaiser , M , Pacanowska , D G , Read , K D , Johansson , N G & Gilbert , I H 2020 , ' Discovery and Optimisation of a Compound Series active against Trypanosoma cruzi, the causative agent of Chagas’ Disease ' , Journal of Medicinal Chemistry , vol. 63 , no. 6 , pp. 3066-3089 ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/2500/2500, name=General Materials Science

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/6afa4a76-03c4-4c5d-94f2-82d908267a7f

الاتاحة: https://discovery.dundee.ac.uk/en/publications/6afa4a76-03c4-4c5d-94f2-82d908267a7f
https://doi.org/10.1021/acs.jmedchem.9b01852
https://discovery.dundee.ac.uk/ws/files/58549678/Trypobase_V28.docx
https://discovery.dundee.ac.uk/ws/files/58549680/Supporting_Information_V8.pdf
http://www.scopus.com/inward/record.url?scp=85081646844&partnerID=8YFLogxK

المؤلفون: Asad, Naeem, McLain, Duncan E., Condon, Alec F., Gore, Sangram, Hampton, Shahienaz E., Vijay, Sauparnika, Williams, John T., Dore, Timothy M.

المساهمون: Division of Chemistry, National Institute of Neurological Disorders and Stroke, National Institute on Drug Abuse, New York University Abu Dhabi

المصدر: ACS Chemical Neuroscience ; volume 11, issue 6, page 939-951 ; ISSN 1948-7193 1948-7193

الاتاحة: http://dx.doi.org/10.1021/acschemneuro.9b00675
http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.9b00675
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.9b00675

المؤلفون: Pérez-Moreno, Guiomar, Sánchez-Carrasco, Paula, Ruiz-Pérez, Luis Miguel, Johansson, Nils Gunnar, Müller, Sylke, Baragaña, Beatriz, Hampton, Shahienaz Emma, Gilbert, Ian Hugh, Kaiser, Marcel, Sarkar, Sandipan, Pandurangan, Thiyagamurthy, Kumar, Vijeesh, González-Pacanowska, Dolores

المصدر: Pérez-Moreno , G , Sánchez-Carrasco , P , Ruiz-Pérez , L M , Johansson , N G , Müller , S , Baragaña , B , Hampton , S E , Gilbert , I H , Kaiser , M , Sarkar , S , Pandurangan , T , Kumar , V & González-Pacanowska , D 2019 , ' Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity ' , Malaria Journal , vol. 18 , 392 , pp. 1-12 . https://doi.org/10.1186/s12936-019-3025-2

مصطلحات موضوعية: Plasmodium falciparum, Deoxyuridine 5′-triphosphate nucleotido-hydrolase, 5′-tritylated deoxyuridine analogues, Mode of action, /dk/atira/pure/subjectarea/asjc/2400/2405, name=Parasitology, /dk/atira/pure/subjectarea/asjc/2700/2725, name=Infectious Diseases

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/92b469bb-eb76-4546-afae-a61ad3e4df08

الاتاحة: https://discovery.dundee.ac.uk/en/publications/92b469bb-eb76-4546-afae-a61ad3e4df08
https://doi.org/10.1186/s12936-019-3025-2
https://discovery.dundee.ac.uk/ws/files/40840692/Final_Published_Version.pdf
http://www.scopus.com/inward/record.url?scp=85064482485&partnerID=8YFLogxK

المؤلفون: Hampton, Shahienaz E., Dore, Timothy M., Schmidt, Walter K.

المساهمون: National Institute of General Medical Sciences, National Institutes of Health

المصدر: Critical Reviews in Biochemistry and Molecular Biology ; volume 53, issue 2, page 157-174 ; ISSN 1040-9238 1549-7798

الاتاحة: http://dx.doi.org/10.1080/10409238.2018.1431606
https://www.tandfonline.com/doi/pdf/10.1080/10409238.2018.1431606

المؤلفون: Hampton, Shahienaz E., Schipani, Alessandro, Bosch-Navarrete, Cristina, Recio, Eliseo, Kaiser, Marcel, Kahnberg, Pia, González-Pacanowska, Dolores, Johansson, Nils Gunnar, Gilbert, Ian H.

وصف الملف: application/pdf

Relation: https://edoc.unibas.ch/31619/1/1-s2.0-S0968089613006159-main.pdf; Hampton, Shahienaz E. and Schipani, Alessandro and Bosch-Navarrete, Cristina and Recio, Eliseo and Kaiser, Marcel and Kahnberg, Pia and González-Pacanowska, Dolores and Johansson, Nils Gunnar and Gilbert, Ian H. (2013) Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the Plasmodium falciparum dUTPase. Bioorganic & medicinal chemistry, 21 (18). pp. 5876-5885.; info:pmid/23916149; urn:ISSN:0968-0896

الاتاحة: http://edoc.unibas.ch/dok/A6174348
https://edoc.unibas.ch/31619/
https://edoc.unibas.ch/31619/1/1-s2.0-S0968089613006159-main.pdf
https://doi.org/10.1016/j.bmc.2013.07.004

المؤلفون: Junta de Andalucía, Ministerio de Economía y Competitividad (España), European Commission, Pérez-Moreno, Guiomar, Sánchez-Carrasco, Paula, Ruiz-Pérez, Luis Miguel, Johansson, N.G., Müller, Sylke, Baragaña, Beatriz, Hampton, Shahienaz E., Gilbert, Ian H., Kaiser, Marcel, Sarkar, Sandipan, Pandurangan, Thiyagamurthy, Kumar, Vijeesh, González-Pacanowska, Dolores

مصطلحات الفهرس: lasmodium falciparum, Deoxyuridine 5′-triphosphate nucleotido-hydrolase, 5′-tritylated deoxyuridine analogues, Mode of action, artículo

URL: http://hdl.handle.net/10261/196266
https://doi.org/10.1186/s12936-019-3025-2
Publisher's version
https://doi.org/10.1186/s12936-019-3025-2
Sí
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2016-79957-R

المؤلفون: Mohammed, Idrees, Hampton, Shahienaz E., Ashall, Louise, Hildebrandt, Emily R., Kutlik, Robert A., Manandhar, Surya P., Floyd, Brandon J., Smith, Haley E., Dozier, Jonathan K., Distefano, Mark D., Schmidt, Walter K., Dore, Timothy M.

المصدر: Bioorganic & Medicinal Chemistry ; volume 24, issue 2, page 160-178 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2015.11.043
https://api.elsevier.com/content/article/PII:S096808961530167X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S096808961530167X?httpAccept=text/plain

المؤلفون: Kahnberg, Pia, Johansson, N.G., Gilbert, Ian H., Hampton, Shahienaz, Harrison, Justin, Sarkar, Sandipan, González-Pacanowska, D.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cfa935999a5454a1190c102befdca2c3
http://hdl.handle.net/10261/135503

المؤلفون: Hampton, Shahienaz E., Baragana, Beatriz, Schipani, Alessandro, Bosch-Navarrete, Cristina, Alexander Musso-Buendia, J., Recio, Eliseo, Kaiser, Marcel, Whittingham, Jean L., Roberts, Shirley M., Shevtsov, Mikhail, Brannigan, James A., Kahnberg, Pia, Brun, Reto, Wilson, Keith S., Gonzalez-Pacanowska, Dolores, Johansson, Nils Gunnar, Gilbert, Ian H.

المصدر: Hampton , S E , Baragana , B , Schipani , A , Bosch-Navarrete , C , Alexander Musso-Buendia , J , Recio , E , Kaiser , M , Whittingham , J L , Roberts , S M , Shevtsov , M , Brannigan , J A , Kahnberg , P , Brun , R , Wilson , K S , Gonzalez-Pacanowska , D , Johansson , N G & Gilbert , I H 2011 , ' Design, Synthesis, and Evaluation of 5 '-Diphenyl Nucleoside Analogues as Inhibitors of the Plasmodium falciparum dUTPase ' , ChemMedChem , vol. ....

مصطلحات موضوعية: antiprotozoal agents, drug design, dUTPase, malaria, nucleosides, DRUG, TARGET

Relation: https://discovery.dundee.ac.uk/en/publications/10796694-989c-4b2b-a0af-15376007268e

الاتاحة: https://discovery.dundee.ac.uk/en/publications/10796694-989c-4b2b-a0af-15376007268e
https://doi.org/10.1002/cmdc.201100255