المؤلفون: Kim, Ho Shin, Ortiz, Diana, Kadayat, Tara Man, Fargo, Corinne M., Hammill, Jared T., Chen, Yizhe, Rice, Amy L., Begley, Kristin L., Shoeran, Gaurav, Pistel, William, Yates, Phillip A., Sanchez, Marco A., Landfear, Scott M., Guy, R. Kiplin

المساهمون: Office of Disease Prevention, National Institute of Allergy and Infectious Diseases

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 11, page 7374-7386 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.3c00056
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00056

المؤلفون: Gaur, Aditya H., Panetta, John C., Smith, Amber M., Dallas, Ronald H., Freeman, Burgess B., Stewart, Tracy B., Tang, Li, John, Elizabeth, Branum, Kristen C., Patel, Nehali D., Ost, Shelley, Heine, Ryan N., Richardson, Julie L., Hammill, Jared T., Bebrevska, Lidiya, Gusovsky, Fabian, Maki, Noritsugu, Yanagi, Toshiharu, Flynn, Patricia M., McCarthy, James S., Chalon, Stephan, Guy, R. Kiplin

المصدر: eBioMedicine ; volume 80, page 104065 ; ISSN 2352-3964

الاتاحة: http://dx.doi.org/10.1016/j.ebiom.2022.104065
https://api.elsevier.com/content/article/PII:S2352396422002468?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2352396422002468?httpAccept=text/plain

المؤلفون: Chen, Yizhe, Zhu, Fangyi, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Freeman, Burgess, White, Karen L., Shackleford, David M., O’Loughlin, Kathleen G., Charman, Susan A., Mirsalis, Jon C., Guy, R. Kiplin

المساهمون: National Institute of Allergy and Infectious Diseases, Medicines for Malaria Venture, NHMRC, St. Jude Children's Research Hospital, American Lebanese Syrian Associated Charities

المصدر: Malaria Journal ; volume 20, issue 1 ; ISSN 1475-2875

الاتاحة: http://dx.doi.org/10.1186/s12936-021-03617-1
http://link.springer.com/content/pdf/10.1186/s12936-021-03617-1.pdf
http://link.springer.com/article/10.1186/s12936-021-03617-1/fulltext.html

المؤلفون: Eagon, Scott, Hammill, Jared T., Fitzsimmons, Kasey, Sienko, Natalie, Nguyen, Brandon, Law, Jarvis, Manjunath, Aashrita, Wilkinson, Steven P., Thompson, Kara, Glidden, Julia Elizabeth, Rice, Amy L., Falade, Mofolusho O., Kimball, Joshua J., DiBernardo, Celine, Guy, R. Kiplin

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 47, page 128216 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2021.128216
https://api.elsevier.com/content/article/PII:S0960894X21004431?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X21004431?httpAccept=text/plain

المؤلفون: Everson, Nikalet, Bach, Jordan, Hammill, Jared T., Falade, Mofolusho O., Rice, Amy L., Guy, R. Kiplin, Eagon, Scott

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 35, page 127818 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2021.127818
https://api.elsevier.com/content/article/PII:S0960894X21000445?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X21000445?httpAccept=text/plain

المؤلفون: Kim, Ho Shin, Hammill, Jared T., Scott, Daniel C., Chen, Yizhe, Rice, Amy L., Pistel, William, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin

المساهمون: National Cancer Institute, University of Kentucky, American Lebanese Syrian Associated Charities, National Institute of General Medical Sciences, Saint Jude Children's Research Hospital

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 9, page 5850-5862 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.1c00035
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00035

المؤلفون: Hammill, Jared T., Sviripa, Vitaliy M., Kril, Liliia M., Ortiz, Diana, Fargo, Corinne M., Kim, Ho Shin, Chen, Yizhe, Rector, Jonah, Rice, Amy L., Domagalska, Malgorzata A., Begley, Kristin L., Liu, Chunming, Rangnekar, Vivek M., Dujardin, Jean-Claude, Watt, David S., Landfear, Scott M., Guy, R. Kiplin

المساهمون: National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 16, page 12152-12162 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.1c00813
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00813

المؤلفون: Eagon, Scott, Hammill, Jared T., Bach, Jordan, Everson, Nikalet, Sisley, Tyler A., Walls, Michael J., Durham, Sierra, Pillai, Dylan R., Falade, Mofolusho O., Rice, Amy L., Kimball, Joshua J., Lazaro, Horacio, DiBernardo, Celine, Kiplin Guy, R.

المساهمون: Grand Challenges Canada

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 30, issue 21, page 127502 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2020.127502
https://api.elsevier.com/content/article/PII:S0960894X20306132?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X20306132?httpAccept=text/plain

المؤلفون: Ortiz, Diana, Guiguemde, W. Armand, Hammill, Jared T., Carrillo, Angela K., Chen, Yizhe, Connelly, Michele, Stalheim, Kayla, Elya, Carolyn, Johnson, Alex, Min, Jaeki, Shelat, Anang, Smithson, David C., Yang, Lei, Zhu, Fangyi, Guy, R. Kiplin, Landfear, Scott M.

المساهمون: Almeida, Igor C., National Institute of Allergy and Infectious Diseases, U.S. Department of Defense, American Syrian Lebanese Associated Charities

المصدر: PLOS Neglected Tropical Diseases ; volume 11, issue 12, page e0006157 ; ISSN 1935-2735

الاتاحة: http://dx.doi.org/10.1371/journal.pntd.0006157
http://dx.plos.org/10.1371/journal.pntd.0006157

المؤلفون: Kim, Ho Shin, Hammill, Jared T., Guy, R. Kiplin

المصدر: Journal of Medicinal Chemistry ; volume 60, issue 7, page 2651-2653 ; ISSN 0022-2623 1520-4804

الاتاحة: https://doi.org/10.1021/acs.jmedchem.7b00299
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b00299

المؤلفون: Yizhe Chen, Fangyi Zhu, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Burgess Freeman, White, Karen L., Shackleford, David M., O’Loughlin, Kathleen G., Charman, Susan A., Mirsalis, Jon C., R. Kiplin Guy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b8b9932de2d49df135c7dbf3d14e69

المؤلفون: Zuniga, Jorge E., Hammill, Jared T., Drory, Omri, Nuss, Jonathan E., Burnett, James C., Gussio, Rick, Wipf, Peter, Bavari, Sina, Brunger, Axel T.

المساهمون: Andreu, Antoni L.

المصدر: PLoS ONE ; volume 5, issue 6, page e11378 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0011378
http://dx.plos.org/10.1371/journal.pone.0011378

المؤلفون: Barrows, Robert D., Hammill, Jared T., Tran, Michael C., Falade, Mofolusho O., Rice, Amy L., Davis, Christopher W., Emge, Thomas J., Rablen, Paul R., Kiplin Guy, R., Knapp, Spencer

المساهمون: Catherine and Joseph Aresty Foundation

المصدر: Bioorganic & Medicinal Chemistry ; volume 28, issue 22, page 115758 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2020.115758
https://api.elsevier.com/content/article/PII:S0968089620305885?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0968089620305885?httpAccept=text/plain

المؤلفون: Eagon, Scott, Hammill, Jared T., Sigal, Martina, Ahn, Kevin J., Tryhorn, Julia E., Koch, Grant, Belanger, Briana, Chaplan, Cory A., Loop, Lauren, Kashtanova, Anna S., Yniguez, Kenya, Lazaro, Horacio, Wilkinson, Steven P., Rice, Amy L., Falade, Mofolusho O., Takahashi, Rei, Kim, Katie, Cheung, Ashley, DiBernardo, Celine, Kimball, Joshua J., Winzeler, Elizabeth A., Eribez, Korina, Mittal, Nimisha, Gamo, Francisco-Javier, Crespo, Benigno, Churchyard, Alisje, García-Barbazán, Irene, Baum, Jake, Anderson, Marc O., Laleu, Benoît, Guy, R. Kiplin

المساهمون: California Polytechnic State University, San Luis Obispo, Wellcome, Medicines for Malaria Venture, Bill and Linda Frost Fund

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 20, page 11902-11919 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.0c01152
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01152

المؤلفون: Kim, Ho Shin, Hammill, Jared T., Scott, Daniel C., Chen, Yizhe, Min, Jaeki, Rector, Jonah, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin

المساهمون: U.S. Department of Health and Human Services, St. Jude Children's Research Hospital

المصدر: Journal of Medicinal Chemistry ; volume 62, issue 18, page 8429-8442 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.9b00410
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00410

المؤلفون: Hammill, Jared T., Bhasin, Deepak, Scott, Daniel C., Min, Jaeki, Chen, Yizhe, Lu, Yan, Yang, Lei, Kim, Ho Shin, Connelly, Michele C., Hammill, Courtney, Holbrook, Gloria, Jeffries, Cynthia, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin

المساهمون: Howard Hughes Medical Institute, National Cancer Institute, St. Jude Children's Research Hospital, National Institute of General Medical Sciences

المصدر: Journal of Medicinal Chemistry ; volume 61, issue 7, page 2694-2706 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.7b01282
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01282

المؤلفون: Hammill, Jared T., Scott, Daniel C., Min, Jaeki, Connelly, Michele C., Holbrook, Gloria, Zhu, Fangyi, Matheny, Amy, Yang, Lei, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin

المساهمون: Howard Hughes Medical Institute, National Cancer Institute, St. Jude Children's Research Hospital, National Institute of General Medical Sciences

المصدر: Journal of Medicinal Chemistry ; volume 61, issue 7, page 2680-2693 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.7b01277
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01277

المؤلفون: Scott, Daniel C., Hammill, Jared T., Min, Jaeki, Rhee, David Y., Connelly, Michele, Sviderskiy, Vladislav O., Bhasin, Deepak, Chen, Yizhe, Ong, Su-Sien, Chai, Sergio C., Goktug, Asli N., Huang, Guochang, Monda, Julie K., Low, Jonathan, Kim, Ho Shin, Paulo, Joao A., Cannon, Joe R., Shelat, Anang A., Chen, Taosheng, Kelsall, Ian R., Alpi, Arno F., Pagala, Vishwajeeth, Wang, Xusheng, Peng, Junmin, Singh, Bhuvanesh, Harper, J. Wade, Schulman, Brenda A., Guy, R. Kiplin

المصدر: Pharmaceutical Sciences Faculty Publications

مصطلحات موضوعية: Chemical tools, Post-translational modifications, Proteins, Screening, X-ray crystallography, Acetylation, Binding Sites, Dose-Response Relationship, Drug, Enzyme Inhibitors, Humans, Models, Molecular, Molecular Structure, NEDD8 Protein, Small Molecule Libraries, Structure-Activity Relationship, Ubiquitin-Protein Ligases, Ubiquitins, Amino Acids, Peptides, and Proteins, Cell and Developmental Biology, Pharmacy and Pharmaceutical Sciences

وصف الملف: application/pdf

Relation: Structural data have been deposited in the Protein DataBank (PDB) with coordinate accession numbers 5V83.pdb (DCN1-NAcM-HIT), 5V86.pdb (DCN1-NAcM-OPT), 5V88.pdb (DCN1:NAcM-COV), 5V89.pdb (DCN4PONY:CUL1WHB). All other data generated or analyzed during this study are included in this published article (and its supplementary information files) or are available from the corresponding author on reasonable request. Supplementary information is available in the online version of the paper.; https://uknowledge.uky.edu/ps_facpub/133; https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1133&context=ps_facpub

الاتاحة: https://uknowledge.uky.edu/ps_facpub/133
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1133&context=ps_facpub

المؤلفون: Keffer, Jessica L., Huecas, Sonia, Hammill, Jared T., Wipf, Peter, Andreu, Jose M., Bewley, Carole A.

المساهمون: Intramural Research Program, National Institutes of Health (NIDDK), Plan Nacional de Investigación, Intramural AIDS Research Fellowship

المصدر: Bioorganic & Medicinal Chemistry ; volume 21, issue 18, page 5673-5678 ; ISSN 0968-0896

الاتاحة: http://dx.doi.org/10.1016/j.bmc.2013.07.033
https://api.elsevier.com/content/article/PII:S0968089613006548?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0968089613006548?httpAccept=text/plain

المؤلفون: Hammill, Jared T., Contreras‐Garcia, Julia, Virshup, Aaron M., Beratan, David N., Yang, Weitao, Wipf, Peter

المصدر: ChemInform ; volume 41, issue 46 ; ISSN 0931-7597 1522-2667

الاتاحة: http://dx.doi.org/10.1002/chin.201046055
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.201046055
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.201046055