المؤلفون: Leurs, Ulrike, Klein, Anders B, McSpadden, Ethan D, Griem-Krey, Nane, Solbak, Sara MØ, Houlton, Josh, Villumsen, Inge S, Vogensen, Stine B, Hamborg, Louise, Gauger, Stine J, Palmelund, Line B, Larsen, Anne Sofie G, Shehata, Mohamed A, Kelstrup, Christian D, Olsen, Jesper V, Bach, Anders, Burnie, Robert O, Kerr, D Steven, Gowing, Emma K, Teurlings, Selina MW, C., Chris, Gee, Christine L, Frølund, Bente, Kornum, Birgitte R, van Woerden, Geeske M, Clausen, Rasmus P, Kuriyan, John, Clarkson, Andrew N, Wellendorph, Petrine

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(31)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Brain Disorders, Neurosciences, 1.1 Normal biological development and functioning, 5.1 Pharmaceuticals, Neurological, Binding Sites, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Carboxylic Acids, Crystallography, X-Ray, Cyclopentanes, Gene Expression Regulation, Enzymologic, HEK293 Cells, Humans, Neuroprotection, Protein Binding, Protein Domains, Signal Transduction, Sodium Oxybate, photoaffinity labeling, x-ray crystallography, HOCPCA, excitotoxicity, photothrombotic storke, photothrombotic stroke

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6fq63908
https://escholarship.org/content/qt6fq63908/qt6fq63908.pdf

المؤلفون: Narayanan, Dilip, Larsen, Anne Sofie G, Gauger, Stine Juul, Adafia, Ruth, Hammershøi, Rikke Bartschick, Hamborg, Louise, Bruus-Jensen, Jesper, Griem-Krey, Nane, Gee, Christine L, Frølund, Bente, Stratton, Margaret M, Kuriyan, John, Kastrup, Jette Sandholm, Langkilde, Annette E, Wellendorph, Petrine, Solbak, Sara M Ø

المصدر: Narayanan , D , Larsen , A S G , Gauger , S J , Adafia , R , Hammershøi , R B , Hamborg , L , Bruus-Jensen , J , Griem-Krey , N , Gee , C L , Frølund , B , Stratton , M M , Kuriyan , J , Kastrup , J S , Langkilde , A E , Wellendorph , P & Solbak , S M Ø 2024 , ' Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity ' , Protein science : a publication of the Protein ....

مصطلحات موضوعية: Calcium-Calmodulin-Dependent Protein Kinase Type 2/chemistry, Crystallography, X-Ray, Humans, Protein Domains, Ligands, Models, Molecular, Scattering, Small Angle, Tryptophan/chemistry, Pyridazines/chemistry, Phosphorylation

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/ligandinduced-camkii-hub-trp403-flip-hub-domain-stacking-and-modulation-of-kinase-activity(7601808a-7564-411f-89d8-48472b085a65).html
https://doi.org/10.1002/pro.5152
https://curis.ku.dk/ws/files/407791133/Protein_Science_2024_Narayanan_Ligand_induced_CaMKII_hub_Trp403_flip_hub_domain_stacking_and_modulation_of_kinase_1_.pdf

المؤلفون: Zutz, Ariane, Hamborg, Louise, Pedersen, Lasse Ebdrup, Kassem, Maher M., Papaleo, Elena, Koza, Anna, Herrgard, Markus, Ingemann Jensen, Sheila, Teilum, Kaare, Lindorff-Larsen, Kresten, Nielsen, Alex Toftgaard

مصطلحات موضوعية: Biotechnology

Relation: https://dx.doi.org/10.11583/dtu.c.5633536

الاتاحة: https://dx.doi.org/10.11583/dtu.c.5633536.v1
https://data.dtu.dk/collections/Data_for_the_publication_A_dual-reporter_system_for_investigating_and_optimizing_protein_translation_and_folding_in_E_coli_/5633536/1

المؤلفون: Zutz, Ariane, Hamborg, Louise, Pedersen, Lasse Ebdrup, Kassem, Maher M., Papaleo, Elena, Koza, Anna, Herrgård, Markus J., Jensen, Sheila Ingemann, Teilum, Kaare, Lindorff-Larsen, Kresten, Nielsen, Alex Toftgaard

المصدر: Zutz , A , Hamborg , L , Pedersen , L E , Kassem , M M , Papaleo , E , Koza , A , Herrgård , M J , Jensen , S I , Teilum , K , Lindorff-Larsen , K & Nielsen , A T 2021 , ' A dual-reporter system for investigating and optimizing protein translation and folding in E. coli ' , Nature Communications , vol. 12 , 6093 . https://doi.org/10.1038/s41467-021-26337-1

وصف الملف: application/pdf

Relation: https://orbit.dtu.dk/en/publications/232de50a-b4b6-47c1-9723-e78c4b6a29bf

الاتاحة: https://orbit.dtu.dk/en/publications/232de50a-b4b6-47c1-9723-e78c4b6a29bf
https://doi.org/10.1038/s41467-021-26337-1
https://backend.orbit.dtu.dk/ws/files/267288145/s41467_021_26337_1.pdf

المؤلفون: Hamborg, Louise, Granata, Daniele, Olsen, Johan G., Roche, Jennifer Virginia, Pedersen, Lasse Ebdrup, Nielsen, Alex Toftgaard, Lindorff-Larsen, Kresten, Teilum, Kaare

المصدر: Communications biology 4(1), 980 (2021). doi:10.1038/s42003-021-02490-7

مصطلحات موضوعية: info:eu-repo/classification/ddc/570

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000686641300006; info:eu-repo/semantics/altIdentifier/pmid/34408246; info:eu-repo/semantics/altIdentifier/issn/2399-3642; https://bib-pubdb1.desy.de/record/465404; https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-03890%22

الاتاحة: https://bib-pubdb1.desy.de/record/465404
https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-03890%22

المؤلفون: Holt, Christian, Hamborg, Louise, Lau, Kelvin, Brohus, Malene, Sørensen, Anders Bundgaard, Larsen, Kamilla Taunsig, Sommer, Cordula, Van Petegem, Filip, Overgaard, Michael Toft, Wimmer, Reinhard

المساهمون: Danish Council for Independent Research, Novo Nordisk Foundation, CIHR

المصدر: Journal of Biological Chemistry ; volume 295, issue 22, page 7620-7634 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.ra120.013430
https://api.elsevier.com/content/article/PII:S0021925817494555?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925817494555?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.RA120.013430

المؤلفون: Tian, Yongsong, Shehata, Mohamed A., Gauger, Stine Juul, Veronesi, Carolina, Hamborg, Louise, Thiesen, Louise, Bruus-Jensen, Jesper, Royssen, Johanne Schlieper, Leurs, Ulrike, Larsen, Anne Sofie G., Krall, Jacob, Solbak, Sara M. O., Wellendorph, Petrine, Frolund, Bente

المصدر: Tian , Y , Shehata , M A , Gauger , S J , Veronesi , C , Hamborg , L , Thiesen , L , Bruus-Jensen , J , Royssen , J S , Leurs , U , Larsen , A S G , Krall , J , Solbak , S M O , Wellendorph , P & Frolund , B 2022 , ' Exploring the NCS-382 Scaffold for CaMKII alpha Modulation : Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKII alpha Hub Domain ' , Journal of Medicinal ....

مصطلحات موضوعية: PROTEIN-KINASE-II, GAMMA-HYDROXYBUTYRIC ACID, GHB LIGANDS DESIGN, ACCURATE DOCKING, SODIUM OXYBATE, BINDING, MECHANISM, RECEPTOR, ANALOGS, GLIDE

الاتاحة: https://researchprofiles.ku.dk/da/publications/exploring-the-ncs382-scaffold-for-camkii-alpha-modulation(31e5545d-d9f7-4b42-9f74-60065b2a7e94).html
https://doi.org/10.1021/acs.jmedchem.2c00805

المؤلفون: Tian, Yongsong, Shehata, Mohamed, Gauger, Stine, Veronesi, Carolina, Hamborg, Louise, Thiesen, Louise, Bruus-Jensen, Jesper, Royssen, Johanne Schlieper, Leurs, Ulrike, Larsen, Anne Sofie, Krall, Jacob, Solbak, Sara, Wellendorph, Petrine, Frølund, Bente

الاتاحة: http://dx.doi.org/10.26434/chemrxiv-2022-54d5q
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/628f376b70432666e047b763/original/exploring-the-ncs-382-scaffold-for-ca-mki-ia-modulation-synthesis-pharmacology-and-biophysical-characterization-of-ph-htba-as-a-novel-high-affinity-brain-penetrant-stabilizer-of-the-ca-mki-ia-hub-domain.pdf

المؤلفون: Tian, Yongsong, Shehata, Mohamed A., Gauger, Stine Juul, Veronesi, Carolina, Hamborg, Louise, Thiesen, Louise, Bruus-Jensen, Jesper, Royssen, Johanne Schlieper, Leurs, Ulrike, Larsen, Anne Sofie G., Krall, Jacob, Solbak, Sara M.Ø., Wellendorph, Petrine, Frølund, Bente

المصدر: Journal of Medicinal Chemistry; 11/24/2022, Vol. 65 Issue 22, p15066-15084, 19p

المؤلفون: Zutz, Ariane, Hamborg, Louise, Pedersen, Lasse Ebdrup, Kassem, Maher M., Papaleo, Elena, Koza, Anna, Herrgård, Markus, Ingemann Jensen, Sheila, Teilum, Kaare, Lindorff-Larsen, Kresten, Nielsen, Alex Toftgaard

مصطلحات موضوعية: Medical biotechnology not elsewhere classified

Relation: https://dx.doi.org/10.11583/dtu.10265420

الاتاحة: https://dx.doi.org/10.11583/dtu.16649593
https://data.dtu.dk/articles/dataset/Flow_cytometry_data_for_publication_A_dual-reporter_system_for_investigating_and_optimizing_protein_translation_and_folding_in_E_coli_/16649593/1

المؤلفون: Hamborg, Louise, Horsted, Emma Wenzel, Johansson, Kristoffer Enøe, Willemoës, Martin, Lindorff-Larsen, Kresten, Teilum, Kaare

المصدر: Hamborg , L , Horsted , E W , Johansson , K E , Willemoës , M , Lindorff-Larsen , K & Teilum , K 2020 , ' Global analysis of protein stability by temperature and chemical denaturation ' , Analytical Biochemistry , vol. 605 , 113863 . https://doi.org/10.1016/j.ab.2020.113863

مصطلحات موضوعية: Chemical denaturation, Data analysis, Protein stability, Temperature denaturation

الاتاحة: https://curis.ku.dk/portal/da/publications/global-analysis-of-protein-stability-by-temperature-and-chemical-denaturation(3cf23565-c6ac-4bbf-bae9-e40215694181).html
https://doi.org/10.1016/j.ab.2020.113863
https://www.biorxiv.org/content/biorxiv/early/2020/04/20/2020.04.20.049429.full.pdf