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1Academic Journal
المؤلفون: Liu, Julio C.Y., Ackermann, Leena, Hoffmann, Saskia, Gál, Zita, Hendriks, Ivo A., Jain, Charu, Morlot, Louise, Tatham, Michael H., McLelland, Gian-Luca, Hay, Ronald T., Nielsen, Michael Lund, Brummelkamp, Thijn, Haahr, Peter, Mailand, Niels
المصدر: Liu , J C Y , Ackermann , L , Hoffmann , S , Gál , Z , Hendriks , I A , Jain , C , Morlot , L , Tatham , M H , McLelland , G-L , Hay , R T , Nielsen , M L , Brummelkamp , T , Haahr , P & Mailand , N 2024 , ' Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation ' , Nature Structural and Molecular Biology , vol. 31 , no. 9 , pp. 1355–1367 . https://doi.org/10.1038/s41594-024-01294-7
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/concerted-sumotargeted-ubiquitin-ligase-activities-of-topors-and-rnf4-are-essential-for-stress-management-and-cell-proliferation(526c5240-e0b3-4140-9402-d8f247821f35).html
https://doi.org/10.1038/s41594-024-01294-7
https://curis.ku.dk/ws/files/408512336/s41594_024_01294_7_2_.pdf -
2Electronic Resource
المؤلفون: CMM Groep Snippert, Cancer, Onderzoek Medische Oncologie, MS Medische Oncologie, Boon, Nicolaas J, Oliveira, Rafaela A, Körner, Pierré-René, Kochavi, Adva, Mertens, Sander, Malka, Yuval, Voogd, Rhianne, van der Horst, Suzanne E M, Huismans, Maarten A, Smabers, Lidwien P, Draper, Jonne M, Wessels, Lodewyk F A, Haahr, Peter, Roodhart, Jeanine M L, Schumacher, Ton N M, Snippert, Hugo J, Agami, Reuven, Brummelkamp, Thijn R
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3Academic Journal
المؤلفون: Nordgaard, Cathrine, Vind, Anna, Constance, Stonadge, Amy, Kjøbsted, Rasmus, Snieckute, Goda, Antas, Pedro, Blasius, Melanie, Reinert, Marie, Sofie, del Val, Ana, Martinez, Bekker‐jensen, Dorte, Breinholdt, Haahr, Peter, Miroshnikova, Yekaterina, A, Mazouzi, Abdelghani, Falk, Sarah, Perrier‐groult, Emeline, Tiedje, Christopher, Li, Xiang, Jakobsen, Jens, Rithamer, Jørgensen, Nicolas, Oldenburg, Wojtaszewski, Jørgen, Fp, Mallein‐gerin, Frederic, Andersen, Jesper, Løvind, Pennisi, Cristian, Pablo, Clemmensen, Christoffer, Kassem, Moustapha, Jafari, Abbas, Brummelkamp, Thijn, Li, Vivian, Sw, Wickström, Sara, A, Olsen, Jesper, Velgaard, Blanco, Gonzalo, Bekker‐jensen, Simon
المساهمون: Laboratoire de Biologie Tissulaire et d'ingénierie Thérapeutique UMR 5305 (LBTI), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)
المصدر: ISSN: 0261-4189.
مصطلحات موضوعية: mechanobiology, muscle contraction, myopathy, ZAKb Subject Categories Musculoskeletal System, Post-translational Modifications & Proteolysis, [SDV]Life Sciences [q-bio]
Relation: hal-03740001; https://hal.science/hal-03740001; https://hal.science/hal-03740001/document; https://hal.science/hal-03740001/file/The%20EMBO%20Journal%20-%202022%20-%20Nordgaard%20-%20ZAK%20%20is%20activated%20by%20cellular%20compression%20and%20mediates%20contraction%E2%80%90induced%20MAP%20kinase.pdf
الاتاحة: https://hal.science/hal-03740001
https://hal.science/hal-03740001/document
https://hal.science/hal-03740001/file/The%20EMBO%20Journal%20-%202022%20-%20Nordgaard%20-%20ZAK%20%20is%20activated%20by%20cellular%20compression%20and%20mediates%20contraction%E2%80%90induced%20MAP%20kinase.pdf
https://doi.org/10.15252/embj.2022111650 -
4Academic Journal
المؤلفون: Nordgaard, Cathrine, Vind, Anna Constance, Stonadge, Amy, Kjobsted, Rasmus, Snieckute, Goda, Antas, Pedro, Blasius, Melanie, Reinert, Marie Sofie, Del Val, Ana Martinez, Bekker-Jensen, Dorte Breinholdt, Haahr, Peter, Miroshnikova, Yekaterina A., Mazouzi, Abdelghani, Falk, Sarah, Perrier-Groult, Emeline, Tiedje, Christopher, Li, Xiang, Jakobsen, Jens Rithamer, Jorgensen, Nicolas Oldenburg, Wojtaszewski, Jorgen F. P., Mallein-Gerin, Frederic, Andersen, Jesper Lovind, Pennisi, Cristian Pablo, Clemmensen, Christoffer, Kassem, Moustapha, Jafari, Abbas, Brummelkamp, Thijn, Li, Vivian S. W., Wickström, Sara A., Olsen, Jesper Velgaard, Blanco, Gonzalo, Bekker-Jensen, Simon
المساهمون: STEMM - Stem Cells and Metabolism Research Program, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Faculty of Medicine
مصطلحات موضوعية: mechanobiology, muscle contraction, myopathy, ZAK beta, NF-KAPPA-B, OSMOTIC-STRESS, P38, TRANSDUCTION, EXERCISE, PATHWAY, GENOME, TAK1, MUTATIONS, CYTOKINE, Biochemistry, cell and molecular biology
وصف الملف: application/pdf
Relation: We thank Dr. Andres Lopez-Contreras (University of Copenhagen, Denmark) for support with mouse husbandry, and Drs. Xiaoyun Lu, Ke Ding (both Jinan University, China), and Paul Pryor (University of York, UK) for providing reagents. We thank Drs. Atul Deshmukh and Alba Gonzalez-Franquesa (both University of Copenhagen, Denmark) for help with C2C12 culture. For providing access to confocal and time-lapse microscopy we acknowledge the Danstem and NNF-CPR imaging platform (University of Copenhagen, Denmark). and Michele M. Nava (University of Helsinki) for help with mechanical manipulations. The Genotype-Tissue Expression (GTEx) Project was supported by the Common Fund of the Office of the Director of the National Institutes of Health, and by NCI, NHGRI, NHLBI, NIDA, NIMH, and NINDS. Work in the Bekker-Jensen lab was supported by grants from the Lundbeck Foundation (R190-2014-4037), The Danish Medical Research Council (9039-00007B), The Novo Nordisk Foundation (NNF21OC0071475), The NEYE Foundation, The Nordea Foundation, and the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement 863911 -PHYRIST). Anna Constance Vind is supported by the BRIDGE-Translational Excellence Program funded by the Novo Nordisk Foundation (NNF20SA0064340). Christoffer Clemmensen receives funding from the Lundbeck Foundation (Fellowship R238-2016-2859) and the Novo Nordisk Foundation (grant number NNF17OC0026114). Novo Nordisk Foundation Center for Basic Metabolic Research is an independent Research Center, based on the University of Copenhagen, Denmark, and partially funded by an unconditional donation from the Novo Nordisk Foundation (www.cbmr.ku.dk) (Grant number NNF18CC0034900). Work in the Wojtaszewski lab was supported by a grant from the Danish Council for Independent Research -Medical Sciences (FSS 8020-00288) and a research grant to Rasmus Kjobsted from the Danish Diabetes Academy, which is funded by the Novo Nordisk Foundation (NFF 17SA0031406). Work in Jesper Olsen's lab at The Novo Nordisk Foundation Center for Protein Research (CPR) is funded in part by a generous donation from the Novo Nordisk Foundation (Grant number NNF14CC0001).; Nordgaard , C , Vind , A C , Stonadge , A , Kjobsted , R , Snieckute , G , Antas , P , Blasius , M , Reinert , M S , Del Val , A M , Bekker-Jensen , D B , Haahr , P , Miroshnikova , Y A , Mazouzi , A , Falk , S , Perrier-Groult , E , Tiedje , C , Li , X , Jakobsen , J R , Jorgensen , N O , Wojtaszewski , J F P , Mallein-Gerin , F , Andersen , J L , Pennisi , C P , Clemmensen , C , Kassem , M , Jafari , A , Brummelkamp , T , Li , V S W , Wickström , S A , Olsen , J V , Blanco , G & Bekker-Jensen , S 2022 , ' ZAK beta is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle ' , EMBO Journal , vol. 41 , no. 17 , 111650 . https://doi.org/10.15252/embj.2022111650; ORCID: /0000-0001-6383-6292/work/156156178; http://hdl.handle.net/10138/348040; 4d59ffb3-ade9-4e3d-9be6-fc069fae1086; 000831039200001
الاتاحة: http://hdl.handle.net/10138/348040
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5Academic Journal
المؤلفون: Vind, Anna Constance, Wu, Zhenzhen, Firdaus, Muhammad Jasrie, Snieckute, Goda, Toh, Gee Ann, Jessen, Malin, Martínez, José Francisco, Haahr, Peter, Andersen, Thomas Levin, Blasius, Melanie, Koh, Li Fang, Maartensson, Nina Loeth, Common, John E A, Gyrd-Hansen, Mads, Zhong, Franklin L, Bekker-Jensen, Simon
المصدر: Mol Cell ; ISSN:1097-4164 ; Volume:84 ; Issue:24
مصطلحات موضوعية: JNK, UV, ZAK-alpha, apoptosis, inflammation, p38, pyroptosis, ribotoxic stress response, skin
Relation: https://doi.org/10.1016/j.molcel.2024.10.044; https://pubmed.ncbi.nlm.nih.gov/39591967; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671030/
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6Academic Journal
المؤلفون: Boon, Nicolaas J, Oliveira, Rafaela A, Körner, Pierré-René, Kochavi, Adva, Mertens, Sander, Malka, Yuval, Voogd, Rhianne, van der Horst, Suzanne E M, Huismans, Maarten A, Smabers, Lidwien P, Draper, Jonne M, Wessels, Lodewyk F A, Haahr, Peter, Roodhart, Jeanine M L, Schumacher, Ton N M, Snippert, Hugo J, Agami, Reuven, Brummelkamp, Thijn R
المساهمون: CMM Groep Snippert, Cancer, Onderzoek Medische Oncologie, MS Medische Oncologie
مصطلحات موضوعية: Apoptosis, Apoptosis Regulatory Proteins, DNA Damage, Humans, Leucine/pharmacology, Protein Biosynthesis, Protein Serine-Threonine Kinases/metabolism, Repressor Proteins, Ribosomes/metabolism, Signal Transduction, Tumor Suppressor Protein p53/metabolism, Journal Article
وصف الملف: application/pdf
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7Academic Journal
المؤلفون: Boon, Nicolaas J., Oliveira, Rafaela A., Körner, Pierré René, Kochavi, Adva, Mertens, Sander, Malka, Yuval, Voogd, Rhianne, van der Horst, Suzanne E.M., Huismans, Maarten A., Smabers, Lidwien P., Draper, Jonne M., Wessels, Lodewyk F.A., Haahr, Peter, Roodhart, Jeanine M.L., Schumacher, Ton N.M., Snippert, Hugo J., Agami, Reuven, Brummelkamp, Thijn R.
المصدر: Boon , N J , Oliveira , R A , Körner , P R , Kochavi , A , Mertens , S , Malka , Y , Voogd , R , van der Horst , S E M , Huismans , M A , Smabers , L P , Draper , J M , Wessels , L F A , Haahr , P , Roodhart , J M L , Schumacher , T N M , Snippert , H J , Agami , R & Brummelkamp , T R 2024 , ' DNA damage induces p53-independent apoptosis through ribosome ....
الاتاحة: https://researchprofiles.ku.dk/da/publications/dna-damage-induces-p53independent-apoptosis-through-ribosome-stalling(31e126cd-7572-4c57-bbd2-bef0cf0d97f6).html
https://doi.org/10.1126/science.adh7950 -
8Academic Journal
المؤلفون: Liu, Julio C. Y., Kühbacher, Ulrike, Larsen, Nicolai B., Borgermann, Nikoline, Garvanska, Dimitriya H., Hendriks, Ivo A., Ackermann, Leena, Haahr, Peter, Gallina, Irene, Guérillon, Claire, Branigan, Emma, Hay, Ronald T., Azuma, Yoshiaki, Nielsen, Michael Lund, Duxin, Julien P., Mailand, Niels
المصدر: Liu , J C Y , Kühbacher , U , Larsen , N B , Borgermann , N , Garvanska , D H , Hendriks , I A , Ackermann , L , Haahr , P , Gallina , I , Guérillon , C , Branigan , E , Hay , R T , Azuma , Y , Nielsen , M L , Duxin , J P & Mailand , N 2021 , ' Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway ' , The EMBO Journal , vol. 40 , no. 18 , ....
مصطلحات موضوعية: DNA repair, DNA-protein crosslinks, SUMO, genome stability, ubiquitin, /dk/atira/pure/subjectarea/asjc/2800/2800, name=General Neuroscience, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology, /dk/atira/pure/subjectarea/asjc/2400/2400, name=General Immunology and Microbiology
وصف الملف: application/pdf
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9Academic Journal
المؤلفون: Hoffmann, Saskia, Pentakota, Satyakrishna, Mund, Andreas, Haahr, Peter, Coscia, Fabian, Gallo, Marta, Mann, Matthias, Taylor, Nicholas M.I., Mailand, Niels
المصدر: Hoffmann , S , Pentakota , S , Mund , A , Haahr , P , Coscia , F , Gallo , M , Mann , M , Taylor , N M I & Mailand , N 2020 , ' FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease ' , EMBO Reports , vol. 21 , no. 10 , e50662 . https://doi.org/10.15252/embr.202050662
مصطلحات موضوعية: cell fitness, chromatin, DNA replication, human genetic disorders, protease
وصف الملف: application/pdf
الاتاحة: https://researchprofiles.ku.dk/da/publications/fam111-protease-activity-undermines-cellular-fitness-and-is-amplified-by-gainoffunction-mutations-in-human-disease(8bdffc51-e250-4534-ad3a-c13cd6d78f79).html
https://doi.org/10.15252/embr.202050662
https://curis.ku.dk/ws/files/250485170/embr.202050662.pdf -
10Academic Journal
المؤلفون: Achuthankutty, Divya, Thakur, Roshan Singh, Haahr, Peter, Hoffmann, Saskia, Drainas, Alexandros P, Bizard, Anna H, Weischenfeldt, Joachim, Hickson, Ian D, Mailand, Niels
المصدر: Achuthankutty , D , Thakur , R S , Haahr , P , Hoffmann , S , Drainas , A P , Bizard , A H , Weischenfeldt , J , Hickson , I D & Mailand , N 2019 , ' Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability ' , The Journal of Cell Biology , vol. 218 , no. 12 , 3943 . https://doi.org/10.1083/jcb.201905064
وصف الملف: application/pdf
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11Academic Journal
المؤلفون: Haahr, Peter, Borgermann, Nikoline, Guo, Xiaohu, Typas, Dimitris, Achuthankutty, Divya, Hoffmann, Saskia, Shearer, Robert, Sixma, Titia K, Mailand, Niels
المصدر: Haahr , P , Borgermann , N , Guo , X , Typas , D , Achuthankutty , D , Hoffmann , S , Shearer , R , Sixma , T K & Mailand , N 2018 , ' ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability ' , Molecular Cell , vol. 70 , no. 1 , pp. 165-174 . https://doi.org/10.1016/j.molcel.2018.02.024
وصف الملف: application/pdf
الاتاحة: https://curis.ku.dk/portal/da/publications/zufsp-deubiquitylates-k63linked-polyubiquitin-chains-to-promote-genome-stability(6e38b77b-2c0c-48e5-aa73-67eeefbf28f5).html
https://doi.org/10.1016/j.molcel.2018.02.024
https://curis.ku.dk/ws/files/215575855/Haahr_et_al._Accepted_Molecular_Cell_2018.pdf -
12Periodical
المؤلفون: Liu, Julio C. Y., Ackermann, Leena, Hoffmann, Saskia, Gál, Zita, Hendriks, Ivo A., Jain, Charu, Morlot, Louise, Tatham, Michael H., McLelland, Gian-Luca, Hay, Ronald T., Nielsen, Michael Lund, Brummelkamp, Thijn, Haahr, Peter, Mailand, Niels
المصدر: Nature Structural and Molecular Biology; 20240101, Issue: Preprints p1-13, 13p
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13Academic Journal
المؤلفون: Schubert, Lisa, Ho, Teresa, Hoffmann, Saskia, Haahr, Peter, Guérillon, Claire, Mailand, Niels
المصدر: Schubert , L , Ho , T , Hoffmann , S , Haahr , P , Guérillon , C & Mailand , N 2017 , ' RADX interacts with single-stranded DNA to promote replication fork stability ' , EMBO Reports , vol. 18 , no. 11 , pp. 1991-2003 . https://doi.org/10.15252/embr.201744877
مصطلحات موضوعية: DNA replication, genome integrity, replication protein A, replication stress, single-stranded DNA
وصف الملف: application/pdf
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14Academic Journal
المؤلفون: Haahr, Peter, Galli, Ricardo A., van den Hengel, Lisa G., Bleijerveld, Onno B., Kazokaitė-Adomaitienė, Justina, Song, Ji-Ying, Kroese, Lona J., Krimpenfort, Paul, Baltissen, Marijke P., Vermeulen, Michiel, Ottenheijm, Coen A. C., Brummelkamp, Thijn R.
المصدر: Haahr , P , Galli , R A , van den Hengel , L G , Bleijerveld , O B , Kazokaitė-Adomaitienė , J , Song , J-Y , Kroese , L J , Krimpenfort , P , Baltissen , M P , Vermeulen , M , Ottenheijm , C A C & Brummelkamp , T R 2022 , ' Actin maturation requires the ACTMAP/C19orf54 protease ' , Science , vol. 377 , no. 6614 , pp. 1533-1537 . https://doi.org/10.1126/science.abq5082
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15Academic Journal
المؤلفون: Haahr, Peter, Hoffmann, Saskia, Tollenaere, Maxim A X, Ho, Teresa, Toledo Lazaro, Luis Ignacio, Mann, Matthias, Bekker-Jensen, Simon, Räschle, Markus, Mailand, Niels
المصدر: Haahr , P , Hoffmann , S , Tollenaere , M A X , Ho , T , Toledo Lazaro , L I , Mann , M , Bekker-Jensen , S , Räschle , M & Mailand , N 2016 , ' Activation of the ATR kinase by the RPA-binding protein ETAA1 ' , Nature Cell Biology , vol. 18 , no. 11 , pp. 1196–1207 . https://doi.org/10.1038/ncb3422
وصف الملف: application/pdf
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16Academic Journal
المؤلفون: Fugger, Kasper, Mistrik, Martin, Neelsen, Kai J, Yao, Qi, Zellweger, Ralph, Kousholt, Arne Nedergaard, Haahr, Peter, Chu, Wai Kit, Bartek, Jiri, Lopes, Massimo, Hickson, Ian D, Sørensen, Claus Storgaard
المصدر: Fugger, Kasper; Mistrik, Martin; Neelsen, Kai J; Yao, Qi; Zellweger, Ralph; Kousholt, Arne Nedergaard; Haahr, Peter; Chu, Wai Kit; Bartek, Jiri; Lopes, Massimo; Hickson, Ian D; Sørensen, Claus Storgaard (2015). FBH1 Catalyzes Regression of Stalled Replication Forks. Cell Reports, 10(10):1749-1757.
مصطلحات موضوعية: Institute of Molecular Cancer Research, 570 Life sciences, biology, 610 Medicine & health
وصف الملف: application/pdf
Relation: https://www.zora.uzh.ch/id/eprint/110119/1/ZORA110119.pdf; info:pmid/25772361; urn:issn:2211-1247
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17Academic Journal
المؤلفون: Fugger, Kasper, Kit Chu, Wai, Haahr, Peter, Nedergaard Kousholt, Arne, Beck, Halfdan, Payne, Miranda J., Hanada, Katsuhiro, Hickson, Ian D., Storgaard Sørensen, Claus
المصدر: Nature Communications ; volume 4, issue 1 ; ISSN 2041-1723
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18Electronic Resource
المؤلفون: Liu, Julio C Y, Kühbacher, Ulrike, Larsen, Nicolai B, Borgermann, Nikoline, Garvanska, Dimitriya H, Hendriks, Ivo A, Ackermann, Leena, Haahr, Peter, Gallina, Irene, Guérillon, Claire, Branigan, Emma, Hay, Ronald T., Azuma, Yoshiaki, Nielsen, Michael Lund, Duxin, Julien P, Mailand, Niels
المصدر: Liu , J C Y , Kühbacher , U , Larsen , N B , Borgermann , N , Garvanska , D H , Hendriks , I A , Ackermann , L , Haahr , P , Gallina , I , Guérillon , C , Branigan , E , Hay , R T , Azuma , Y , Nielsen , M L , Duxin , J P & Mailand , N 2021 , ' Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway ' , E M B O Journal , vol. 40 , e107413 .
مصطلحات الفهرس: article
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19Academic Journal
المؤلفون: Haahr, Peter A., Jacobsen, Claus, Christensen, Maria E.
المساهمون: Meda, a Mylan company
المصدر: International Forum of Allergy & Rhinology ; volume 9, issue 4, page 388-395 ; ISSN 2042-6976 2042-6984
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20Academic JournalMP-AzeFlu provides rapid and effective allergic rhinitis control in real life : a pan-European study
المؤلفون: Klimek, Ludger, Bachert, Claus, Stjärne, Par, Dollner, Ralph, Larsen, Petter, Haahr, Peter, Agache, Ioana, Scadding, Glenis, Price, David
المصدر: ALLERGY AND ASTHMA PROCEEDINGS ; ISSN: 1088-5412 ; ISSN: 1539-6304
مصطلحات موضوعية: Medicine and Health Sciences, AQUEOUS NASAL SPRAY, QUALITY-OF-LIFE, FLUTICASONE PROPIONATE, INTRANASAL THERAPY, MOMETASONE FUROATE, PERENNIAL RHINITIS, ATOPIC DISEASES, ARIA GUIDELINES, PRIMARY-CARE, ASTHMA
وصف الملف: application/pdf
Relation: https://biblio.ugent.be/publication/8507908; http://hdl.handle.net/1854/LU-8507908; http://dx.doi.org/10.2500/aap.2016.37.3979; https://biblio.ugent.be/publication/8507908/file/8507909