المؤلفون: Yikyung Ko, Jihye yoo, Hong-ryul Jung, Hyerim Lim, YeongDeok Lee, Se Hyuk Kim, Dong Guk Shin, Serin Cho, Myung hoe Heo, Haelee Kim, Ha Yeon Cho, Ah Reum Han, Eunhwa Ko, Hwan Geun Choi, Deakwon Kim, Sunghwan Kim

المصدر: Cancer Research. 83:P1-11

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2312641c1587a804507c69288b933ae0
https://doi.org/10.1158/1538-7445.sabcs22-p1-11-03

المؤلفون: Younho Lee (5409854), Hyunkyung Kim (2902602), Haelee Kim (5738474), Ha Yeon Cho (10756372), Jun-Goo Jee (627412), Kyung-Ah Seo (10743561), Jung Beom Son (2474797), Eunhwa Ko (531562), Hwan Geun Choi (750017), Nam Doo Kim (77751), Ikyon Kim (1478845)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Cancer, Infectious Diseases, Plant Biology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, X-ray crystal structure analysis, apical dual-specificity protein kinase, pyrimidine -5-carbonitrile Scaffold, 7 H, MPS 1 inhibitor, Monopolar Spindle 1 Inhibitor Tripl., TNBC cell proliferation, breast-cancer subtype, Monopolar spindle 1 kinase, vivo evaluation, relapse rates

Relation: https://figshare.com/articles/journal_contribution/X_ray_Crystal_Structure-Guided_Design_and_Optimization_of_7_i_H_i_Pyrrolo_2_3_i_d_i_pyrimidine-5-carbonitrile_Scaffold_as_a_Potent_and_Orally_Active_Monopolar_Spindle_1_Inhibitor/14534565

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00542.s005

المؤلفون: Ha Yeon Cho, Ju Rhee Lee

المصدر: Korean Journal of Child Studies. 43:187-200

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3495f5bc7a713b2c3ffe1c2e39726f60
https://doi.org/10.5723/kjcs.2022.43.3.187

المؤلفون: Sunghoon Kim, Seong-Jin Kim, Jung Min Han, Min Guo, Myung Hee Kim, Song-Yee Jang, Beom Sik Kang, Ha Yeon Cho, Ji-Hyun Lee, Jin Young Lee, Dae Gyu Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604fe3f14dc9902a652d56a3340f667a
https://doi.org/10.1158/0008-5472.22411161

المؤلفون: Sunghoon Kim, Seong-Jin Kim, Jung Min Han, Min Guo, Myung Hee Kim, Song-Yee Jang, Beom Sik Kang, Ha Yeon Cho, Ji-Hyun Lee, Jin Young Lee, Dae Gyu Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7dfbd05a2b7c2e4ad14b19640b86867
https://doi.org/10.1158/0008-5472.c.6508167.v1

المؤلفون: Sunghoon Kim, Seong-Jin Kim, Jung Min Han, Min Guo, Myung Hee Kim, Song-Yee Jang, Beom Sik Kang, Ha Yeon Cho, Ji-Hyun Lee, Jin Young Lee, Dae Gyu Kim

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f213e5a24279ac6e72e9a2e1088fd72
https://doi.org/10.1158/0008-5472.22411173

المؤلفون: Ha Yeon Cho, Hyun-Joo Lee, Dong Kyu Kim, Beom Sik Kang, Jiwon Kong, Sunghoon Kim

المصدر: Nucleic Acids Research
Nucleic acids research, vol 49, iss 11

مصطلحات موضوعية: Models, Molecular, Methionine—tRNA ligase, Stereochemistry, AcademicSubjects/SCI00010, Protein Conformation, Methionine-tRNA Ligase, Biology, Crystallography, X-Ray, RNA, Transfer, Models, Structural Biology, Information and Computing Sciences, Catalytic Domain, Genetics, Humans, Binding site, chemistry.chemical_classification, DNA ligase, Crystallography, Binding Sites, Tumor Suppressor Proteins, Molecular, Biological Sciences, Peptide Elongation Factors, TRNA binding, Methionyl-tRNA synthetase, Transfer, Cytosol, Zinc, chemistry, Transfer RNA, Domain (ring theory), X-Ray, RNA, Generic health relevance, Peptides, Environmental Sciences, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef4dae9056b487da7039b7e2473b0d8
http://europepmc.org/articles/PMC8216282

المؤلفون: Seo Kyung Ah, Son Jung Beom, Ikyon Kim, Jun Goo Jee, Nam Doo Kim, Kim Hyunkyung, Haelee Kim, Eunhwa Ko, Hwan Geun Choi, Younho Lee, Ha Yeon Cho

المصدر: Journal of Medicinal Chemistry. 64:6985-6995

مصطلحات موضوعية: 0303 health sciences, Scaffold, Pyrimidine, Crystal structure, Tnbc cell, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Orally active, chemistry, In vivo, Drug Discovery, Cancer research, Molecular Medicine, Protein kinase A, Monopolar spindle, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::efd1e225ff0d0ed781f23a424e08089d
https://doi.org/10.1021/acs.jmedchem.1c00542

المؤلفون: Hyun-Joo Lee, Ha Yeon Cho, Jeen-Woo Park, Hyun-Shik Lee, Hyo Je Cho, Oh-Shin Kwon, Beom Sik Kang, Dong-Seok Lee

المصدر: International Journal of Biological Macromolecules. 131:912-924

مصطلحات موضوعية: Models, Molecular, Conformational change, Subfamily, Protein Conformation, Stereochemistry, Phosphatase, Peptide, 02 engineering and technology, Crystallography, X-Ray, Biochemistry, Catalysis, Substrate Specificity, Dephosphorylation, 03 medical and health sciences, chemistry.chemical_compound, Structural Biology, Catalytic Domain, Phosphoprotein Phosphatases, Humans, Amino Acid Sequence, Molecular Biology, Pyridoxal, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, biology, Spectrum Analysis, Active site, General Medicine, 021001 nanoscience & nanotechnology, Phosphoric Monoester Hydrolases, Enzyme, chemistry, biology.protein, 0210 nano-technology, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5511865aa1b1aef1faf97ee0ccbe9262
https://doi.org/10.1016/j.ijbiomac.2019.03.097

المؤلفون: Younho, Lee, Hyunkyung, Kim, Haelee, Kim, Ha Yeon, Cho, Jun-Goo, Jee, Kyung-Ah, Seo, Jung Beom, Son, Eunhwa, Ko, Hwan Geun, Choi, Nam Doo, Kim, Ikyon, Kim

المصدر: Journal of medicinal chemistry. 64(10)

مصطلحات موضوعية: Mice, Inbred ICR, Binding Sites, Transplantation, Heterologous, Administration, Oral, Breast Neoplasms, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Protein-Tyrosine Kinases, Crystallography, X-Ray, Molecular Docking Simulation, Mice, Structure-Activity Relationship, Pyrimidines, Cell Line, Tumor, Drug Design, Animals, Humans, Female, Pyrroles, Protein Kinase Inhibitors, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5318148535a7bed12adc0dfbcf524041
https://pubmed.ncbi.nlm.nih.gov/33942608

المؤلفون: Kwangwoo Hwang, SeoHyun Jo, Jieun Choi, Ga-young Choi, Jiseon Choi, Ji-Hye Kwon, Dong-Guk Shin, Jiyeon Kim, Se-Hyuk Kim, Haelee Kim, Ha Yeon Cho, Jung Beom Son, Nam Doo Kim, Hwan Geun Choi, Daekwon Kim, Sunghwan Kim

المصدر: Cancer Research. 82:LB521-LB521

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eed613962e35bc81098d392570afd873
https://doi.org/10.1158/1538-7445.am2022-lb521

المؤلفون: Hyun-Shik Lee, Hyo Je Cho, Oh-Shin Kwon, Jeen-Woo Park, Tae Lin Huh, Ha Yeon Cho, Beom Sik Kang

المصدر: Journal of Biological Inorganic Chemistry

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Calorimetry, Crystallography, X-Ray, Biochemistry, Dithiothreitol, Divalent, Inorganic Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Mice, Cytosol, Oxidoreductase, NADP+-dependent cytosolic isocitrate dehydrogenase, Animals, Enzyme activity, Cysteine, Oxidative decarboxylation, Chelating Agents, chemistry.chemical_classification, Original Paper, 030102 biochemistry & molecular biology, biology, Crystal structure, Glutathione, Enzyme assay, Isocitrate Dehydrogenase, Enzyme Activation, 030104 developmental biology, Isocitrate dehydrogenase, chemistry, biology.protein, Spectrophotometry, Ultraviolet, NADP, Cadmium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9af93808ff2cdcb945aa096d7045886
http://europepmc.org/articles/PMC6060952

المؤلفون: Ha Yeon Cho, Kyeong Sik Jin, Beom Sik Kang, Hyun-Joo Lee, Sunghoon Kim, Dong Kyu Kim, Yoon Seo Choi

المصدر: Journal of molecular biology. 431(22)

مصطلحات موضوعية: Stereochemistry, Aspartate-tRNA Ligase, Methionine-tRNA Ligase, Amino Acyl-tRNA Synthetases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tetramer, Structural Biology, Catalytic Domain, Protein biosynthesis, Humans, Molecular Biology, 030304 developmental biology, Glutathione Transferase, chemistry.chemical_classification, 0303 health sciences, DNA ligase, Chemistry, Aminoacyl tRNA synthetase, Tumor Suppressor Proteins, Nuclear Proteins, EPRS, Peptide Elongation Factors, Amino acid, Protein Biosynthesis, Transfer RNA, Linker, 030217 neurology & neurosurgery, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d0eae29e0b244a502ace3277885cd5
https://pubmed.ncbi.nlm.nih.gov/31473157

المؤلفون: Myung Hee Kim, Dae Gyu Kim, Ji Hyun Lee, Jin Young Lee, Min Guo, Beom Sik Kang, Seong-Jin Kim, Song Yee Jang, Jung Min Han, Sunghoon Kim, Ha Yeon Cho

المصدر: Cancer Research. 76:3422-3436

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Cancer Research, Lung Neoplasms, Immunoprecipitation, Ubiquitin-Protein Ligases, p38 mitogen-activated protein kinases, Blotting, Western, Mice, Nude, Apoptosis, Biology, Real-Time Polymerase Chain Reaction, medicine.disease_cause, p38 Mitogen-Activated Protein Kinases, DNA-binding protein, Immunoenzyme Techniques, Proto-Oncogene Proteins c-myc, Mice, 03 medical and health sciences, medicine, Animals, Humans, RNA, Messenger, Nuclear export signal, Cells, Cultured, Cell Proliferation, Mice, Knockout, Mice, Inbred BALB C, Reverse Transcriptase Polymerase Chain Reaction, Ubiquitin, Tumor Suppressor Proteins, DNA Helicases, Ubiquitination, RNA-Binding Proteins, Fibroblasts, Embryo, Mammalian, Peptide Elongation Factors, Xenograft Model Antitumor Assays, DNA-Binding Proteins, 030104 developmental biology, Oncology, Cancer research, Phosphorylation, Female, Carcinogenesis, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174b7d06feaa1f9df38eac1ec2e6af86
https://doi.org/10.1158/0008-5472.can-15-3255

المؤلفون: Michael J. Hautus, Hye Seong Lee, Ha Yeon Cho, In Ah Kim

المصدر: Food Quality and Preference. 81:103857

مصطلحات موضوعية: 0303 health sciences, Measure (data warehouse), Nutrition and Dietetics, 030309 nutrition & dietetics, business.industry, Metacognition, Context (language use), 04 agricultural and veterinary sciences, Test method, Response bias, 040401 food science, Test (assessment), 03 medical and health sciences, 0404 agricultural biotechnology, Statistics, New product development, Product (category theory), Psychology, business, Food Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::97ea3f5185b635b9678692c25354191e
https://doi.org/10.1016/j.foodqual.2019.103857

المؤلفون: Sung-Wook Shin, Ho-Sang Moon, C.J. Lim, Ha-Yeon Cho, Ji-Yong Chung, Sung-Taek Chung

المصدر: HCI International 2018 – Posters' Extended Abstracts ISBN: 9783319922782
HCI (29)

مصطلحات موضوعية: Rehabilitation, Recall, Working memory, medicine.medical_treatment, 05 social sciences, Cognitive flexibility, Cognition, 030210 environmental & occupational health, 050105 experimental psychology, Cognitive training, 03 medical and health sciences, 0302 clinical medicine, medicine, 0501 psychology and cognitive sciences, Cognitive rehabilitation therapy, Verbal memory, Psychology, Cognitive psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8e7a612c3bbbe30f66be9662aed12bb0
https://doi.org/10.1007/978-3-319-92279-9_11

المؤلفون: Beom Sik Kang, Ha Yeon Cho

المصدر: Biochemical and Biophysical Research Communications. 444:651-655

مصطلحات موضوعية: Models, Molecular, Mutant, Biophysics, Biology, Biochemistry, Mycobacterium tuberculosis, Serine, Bacterial Proteins, Gene expression, Humans, Point Mutation, Tuberculosis, Phosphorylation, Molecular Biology, Kinase, Gene Expression Regulation, Bacterial, Cell Biology, biology.organism_classification, Two-component regulatory system, Protein Structure, Tertiary, DNA-Binding Proteins, Response regulator, bacteria, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd48b1d5441ae17f250d881b156df94
https://doi.org/10.1016/j.bbrc.2014.01.128

المؤلفون: Myung Hee Kim, Beom Sik Kang, Hyo Je Cho, Si Wouk Kim, Kyung-Jin Kim, Ha Yeon Cho

المصدر: Journal of Structural Biology. 175:39-48

مصطلحات موضوعية: Indoles, Stereochemistry, Flavin-containing monooxygenase, Crystallography, X-Ray, Protein Structure, Secondary, chemistry.chemical_compound, Bacterial Proteins, Structural Biology, Indoxyl, Oxidoreductase, Catalytic Domain, Enzyme Inhibitors, Binding site, Enzyme Assays, Indole test, chemistry.chemical_classification, Binding Sites, biology, Chemistry, Active site, Monooxygenase, Recombinant Proteins, Protein Structure, Tertiary, Enzyme, Amino Acid Substitution, Biochemistry, Mutagenesis, Site-Directed, Oxygenases, biology.protein, Piscirickettsiaceae, NADP

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0d246f76e8f0af0bc366e6abad9498
https://doi.org/10.1016/j.jsb.2011.04.007

المؤلفون: Hyo Je Cho, Ha Yeon Cho, Beom Sik Kang, Jeong-Il Oh, Young-Min Kim

المصدر: Journal of Biological Chemistry. 284:13057-13067

مصطلحات موضوعية: Hemeproteins, Models, Molecular, Protein Folding, Iron, Heme, Protamine Kinase, Flavin group, Crystallography, X-Ray, behavioral disciplines and activities, Biochemistry, Ferrous, chemistry.chemical_compound, Bacterial Proteins, mental disorders, Molecular Biology, Histidine, Chemistry, Hydrogen bond, Mycobacterium tuberculosis, Cell Biology, Oxygen tension, Oxygen, Crystallography, Protein Structure and Folding, Biophysics, Protein folding, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af765f4183ca38cd73b0a9adb3347f0
https://doi.org/10.1074/jbc.m808905200

المؤلفون: Hoi Kyoung Kim, Yoon Seo Choi, Chi Yong Eom, Beom Sik Kang, Min Guo, Sunghoon Kim, Sangmin Lee, Jong H. Kim, Yeon Gil Kim, Hyo Je Cho, Seo Jin Maeng, Jeong Min Chung, Ha Yeon Cho, Hyun Suk Jung

مصطلحات موضوعية: Scaffold protein, Protein Conformation, education, Molecular Sequence Data, CHO Cells, Methionine-tRNA Ligase, Biology, Biochemistry, Protein–protein interaction, Amino Acyl-tRNA Synthetases, chemistry.chemical_compound, Protein structure, Cricetulus, Tetramer, Cricetinae, Protein Interaction Mapping, Fluorescence Resonance Energy Transfer, Animals, Humans, Amino Acid Sequence, Molecular Biology, Peptide sequence, Glutathione Transferase, Chromatography, Sequence Homology, Amino Acid, Aminoacyl tRNA synthetase, Tumor Suppressor Proteins, Nuclear Proteins, Cell Biology, respiratory system, EPRS, Peptide Elongation Factors, humanities, Protein Structure, Tertiary, Microscopy, Electron, chemistry, Multiprotein Complexes, Transfer RNA, Protein Structure and Folding, Biophysics, human activities, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639bbc0dd64f618e1ee91d000e7c7107
https://europepmc.org/articles/PMC4705937/