المؤلفون: Hietamaki, Johanna, Hero, Matti, Holopainen, Elina, Kansakoski, Johanna, Vaaralahti, Kirsi, Iivonen, Anna-Pauliina, Miettinen, Paivi J., Raivio, Taneli

المساهمون: Raivio Group, Children's Hospital, Department of Physiology, Department of Obstetrics and Gynecology, HUS Gynecology and Obstetrics, Research Programs Unit, Research Programme for Molecular Neurology, Timo Pyry Juhani Otonkoski / Principal Investigator, HUS Children and Adolescents

مصطلحات موضوعية: IDIOPATHIC HYPOGONADOTROPIC HYPOGONADISM, FUNCTIONAL HYPOTHALAMIC AMENORRHEA, HOMOZYGOUS R262Q MUTATION, HORMONE RECEPTOR, DELAYED PUBERTY, CONSTITUTIONAL DELAY, DIAGNOSIS, REVERSAL, GROWTH, TESTOSTERONE, Biomedicine, Gynaecology and paediatrics

وصف الملف: application/pdf

Relation: This work was supported by The Academy of Finland (268356), http://www.aka.fi/en/; Foundation for Pediatric Research (7495), http://www.lastentautientutkimussaatio.fi/; Sigrid Juselius Foundation (2613), http://sigridjuselius.fi/en/main-page/; and the Finnish Medical Foundation (011115), http://www.laaketieteensaatio.fi/fin/in_english/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.; Hietamaki , J , Hero , M , Holopainen , E , Kansakoski , J , Vaaralahti , K , Iivonen , A-P , Miettinen , P J & Raivio , T 2017 , ' GnRH receptor gene mutations in adolescents and young adults presenting with signs of partial gonadotropin deficiency ' , PLoS One , vol. 12 , no. 11 , 0188750 . https://doi.org/10.1371/journal.pone.0188750; ORCID: /0000-0002-5184-9616/work/40070184; http://hdl.handle.net/10138/229916; 32d8f4f3-8e82-40aa-938f-44d016f18a8e; 85035764135; 000416402000056

الاتاحة: http://hdl.handle.net/10138/229916

المؤلفون: Matti Hero, Anna-Pauliina Iivonen, Johanna Hietamäki, Johanna Känsäkoski, Kirsi Vaaralahti, Elina Holopainen, Päivi J. Miettinen, Taneli Raivio

المساهمون: Raivio Group, Children's Hospital, Department of Physiology, Department of Obstetrics and Gynecology, HUS Gynecology and Obstetrics, Research Programs Unit, Research Programme for Molecular Neurology, Timo Pyry Juhani Otonkoski / Principal Investigator, HUS Children and Adolescents

المصدر: PLoS ONE
PLoS ONE, Vol 12, Iss 11, p e0188750 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, Physiology, REVERSAL, Twins, Hypoestrogenism, lcsh:Medicine, Monozygotic twin, Gene mutation, Adolescents, Compound heterozygosity, Biochemistry, Families, Endometrium, Endocrinology, 0302 clinical medicine, 3123 Gynaecology and paediatrics, TESTOSTERONE, Medicine and Health Sciences, Lipid Hormones, lcsh:Science, Children, Multidisciplinary, Estradiol, GNRHR, DELAYED PUBERTY, Androgens, GROWTH, Female, CONSTITUTIONAL DELAY, Congenital Hypogonadotropic Hypogonadism, Anatomy, medicine.symptom, Research Article, Adult, Delayed puberty, medicine.medical_specialty, Adolescent, 030209 endocrinology & metabolism, IDIOPATHIC HYPOGONADOTROPIC HYPOGONADISM, DIAGNOSIS, Young Adult, 03 medical and health sciences, Internal medicine, medicine, FUNCTIONAL HYPOTHALAMIC AMENORRHEA, Humans, Endocrine Physiology, business.industry, lcsh:R, Puberty, Uterus, Reproductive System, Biology and Life Sciences, Gonadotropin deficiency, medicine.disease, Hormones, Young Adults, 030104 developmental biology, Age Groups, HORMONE RECEPTOR, Mutation, People and Places, lcsh:Q, Population Groupings, 3111 Biomedicine, business, HOMOZYGOUS R262Q MUTATION, Gonadotropins, Receptors, LHRH, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e230992421291f49ac9411dc4270013
http://hdl.handle.net/10138/229916