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1
المؤلفون: Ana Vanessa Fernandes Ferreira, Teresa Matamá, Nuno G. Azoia, Joana Cunha, Artur Cavaco-Paulo, Artur Ribeiro, Egipto Antunes
المساهمون: Universidade do Minho
المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Biotechnology Reports
Biotechnology Reports, Vol 22, Iss, Pp-(2019)مصطلحات موضوعية: UM, ultramarine protein, UM10, ultramarine engineered without the last 11th β-strand, lcsh:Biotechnology, HNE, human neutrophil elastase, 010402 general chemistry, 01 natural sciences, Applied Microbiology and Biotechnology, Article, Green fluorescent protein, 03 medical and health sciences, Chromoprotein, lcsh:TP248.13-248.65, pep11, synthetic peptide equivalent to free 11th β-sheet of ultramarine, Moiety, E11, 11th β-strand of ultramarine inserted in a eglin c portion with an HNE cleavage sequence, 030304 developmental biology, ComputingMethodologies_COMPUTERGRAPHICS, High concentration, RMSF, root-mean-square fluctuation, 0303 health sciences, Chemistry, Chromogenic, Molecular dynamics simulations, Split GFP, Elastase, Ultramarine (UM), Substrate (chemistry), Chromogenic GFP-like proteins, Proteases, 0104 chemical sciences, Biophysics, Biosensor, pNa, p-nitroaniline, Human neutrophil elastase (HNE), Biotechnology
وصف الملف: application/pdf
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2
المؤلفون: Liu-Qiang Zhang, Yu-Juan Wu, Hao-Yang Xu, Jie Zhang, Xing Zhang, Yiming Li
المصدر: Journal of Ethnopharmacology
مصطلحات موضوعية: Lipopolysaccharides, Male, Chronic bronchitis, HPLC, High-performance liquid chromatography, Human neutrophil elastase, DEX, Dexamethasone, Pharmacology, chemistry.chemical_compound, Leukocyte Count, 0302 clinical medicine, Drug Discovery, Bioassay, Caco-2 cells, Lung, LPS, Lipopolysaccharide, LLs, Loquat leaves, 0303 health sciences, Mice, Inbred BALB C, biology, Chemistry, Elastase, LC-MS, Liquid chromatography–mass spectrometry, HNE, Human neutrophil elastase, Loquat leaves, 030220 oncology & carcinogenesis, Neutrophil elastase, Cytokines, Bronchoalveolar Lavage Fluid, TCLL, Triterpenoid composition of loquat leaves, Acute Lung Injury, Eriobotrya, Lung injury, Article, 03 medical and health sciences, Ursolic acid, 1H NMR, Proton nuclear magnetic resonance, In vivo, PTs, Pentacyclic triterpenoids, BALF, Bronchoalveolar lavage fluid, Animals, Humans, Pentacyclic triterpenoids, 030304 developmental biology, ALI, Acute lung injury, DMSO, Dimethyl sulfoxide, biology.organism_classification, Triterpenes, Plant Leaves, biology.protein, Leukocyte Elastase, UA, Ursolic acid
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3
المؤلفون: Andrew L. Durham, Gaetano Caramori, Kian Fan Chung, Ian M. Adcock
المصدر: Translational Research
مصطلحات موضوعية: Asthma, COPD, corticosteroids, new drugs, monoclonal antibodies, pulmonary pharmacology, sIL-4R, soluble IL-4 receptor, PDE, phosphodiesterase, medicine.medical_treatment, FKBP51, FK506-binding protein 51, Anti-Inflammatory Agents, Disease, Review Article, ACQ, Asthma Control Questionnaire, Targeted therapy, corticosteroids, CLCA1, chloride channel regulator 1, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, FeNO, fraction of exhaled nitric oxide, SAL, salmeterol, 030212 general & internal medicine, TSLP, Thymic stromal lymphopoietin, Medicine(all), CXCR, CXC chemokine receptor, SERPINB2, serpin peptidase inhibitor, General Medicine, HNE, Human neutrophil elastase, CS, corticosteroids, Obstructive lung disease, mRNA, messenger RNA, 3. Good health, FP, fluticasone propionate, AHR, airway hyperresponsiveness, COPD, chronic obstructive lung disease, Salmeterol, BAL, bronchoalveolar lavage, medicine.symptom, medicine.drug, PI3K, phosphoinositide-3-kinase, Socio-culturale, Inflammation, TORCH, Towards a Revolution in COPD Health, Fluticasone propionate, 03 medical and health sciences, FEV1, Forced expiratory volume in 1 second, RT-qPCR, Real time quantative polymerase chain reaction, Physiology (medical), medicine, Humans, EGF, epidermal growth factor, Biochemistry, medical, GR, glucocorticoid receptor, business.industry, Biochemistry (medical), GOLD, The Global Initiative for Chronic Obstructive Lung Disease, Public Health, Environmental and Occupational Health, medicine.disease, HDACs, histone deacetylases, ICS, inhaled corticosteroids, respiratory tract diseases, EGFR, epidermal growth factor receptor, clade B, member 2, IgE, Immunoglobulin E, 030228 respiratory system, Immunology, ACOS, asthma-COPD overlap syndrome, GM-CSF, Granulocyte-macrophage colony-stimulating factor, MAbs, monoclonal antibodies, LABAs, Long-acting beta-adrenoceptor agonists, business, Asthma, COPD, corticosteroids
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4
المؤلفون: Brigitte Arbeille, Francis Gauthier, Déborah Bréa, Claire Chevaleyre, Sylvie Attucci, Mustapha Si-Tahar, Julien Gaillard, Nathalie Winter, François Meurens, Alice V. Dubois, Marie-Lise Jourdan
المساهمون: UMR 1100, Institut National de la Santé et de la Recherche Médicale (INSERM), Infectiologie et Santé Publique (UMR ISP), Institut National de la Recherche Agronomique (INRA)-Université de Tours, Département des Microscopies, Université Francois Rabelais [Tours], Vaincre la Mucoviscidose [grant numbers RC0704 and RCB0901] and the Institut National de la Recherche Agronomique (INRA), ProdInra, Migration, Université de Tours (UT), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT), PPF 'Analyses des Systèmes Biologiques', Nutrition, croissance et cancer (U 1069) (N2C), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours (UT), Université de Tours (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
المصدر: Biochemical Journal
Biochemical Journal, Portland Press, 2012, 447 (3), pp.363-370. ⟨10.1042/bj20120818⟩
Biochemical Journal, 2012, 447 (3), pp.363-370. ⟨10.1042/bj20120818⟩
Biochemical Journal, Portland Press, 2012, 447 (3), pp.363-370. ⟨10.1042/BJ20120818⟩مصطلحات موضوعية: EDDnp, N-(2,4-dinitrophenyl) ethylenediamine, NSP, neutrophil serine protease, Neutrophils, Swine, medicine.medical_treatment, [SDV]Life Sciences [q-bio], HNE, human neutrophil elastase, Cathepsin G, ECL, enhanced chemiluminescence, Biochemistry, Cell Degranulation, Neutrophil Activation, Serine, chemistry.chemical_compound, 0302 clinical medicine, NET, neutrophil extracellular trap, PEM, protein epitope mimetic, Calcimycin, 0303 health sciences, dsDNA, double-stranded DNA, Elastase, Abz, o-aminobenzoic acid, neutrophil, Transmembrane protein, 3. Good health, Pr3, protease 3, Calcium Ionophores, 030220 oncology & carcinogenesis, Pseudomonas aeruginosa, [SDV.IMM]Life Sciences [q-bio]/Immunology, Serine Proteinase Inhibitors, Research Article, Proteases, Staphylococcus aureus, [SDV.IMM] Life Sciences [q-bio]/Immunology, Biology, In Vitro Techniques, FRET, fluorescence resonance energy transfer, Microbiology, PMN, polymorphonuclear neutrophil, neutrophil serine protease, 03 medical and health sciences, Species Specificity, medicine, Animals, Humans, NE, neutrophil elastase, SEM, scanning electron microscopy, cat G, cathepsin G, Molecular Biology, SLPI, secretory leucocyte protease inhibitor, pig model, 030304 developmental biology, CF, cystic fibrosis, Protease, neutrophil extracellular trap, α1-Pi, α1-proteinase inhibitor, lung inflammation, Cell Biology, Neutrophil extracellular traps, Pneumonia, PE, phycoerythrin, Disease Models, Animal, chemistry, Serine Proteases, CFTR, CF transmembrane conductance regulator, ACT, α1-antichymotrypsin, pathogen
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5Academic Journal
المؤلفون: Wibley, K. S., Bansal, S., Barlow, D. J.
المساهمون: KING'S COLL LONDON (UNITED KINGDOM)
المصدر: DTIC AND NTIS
مصطلحات موضوعية: Biochemistry, Pharmacology, ENZYME INHIBITORS, PEPTIDE HYDROLASES, SERINE, EMPHYSEMA, GREAT BRITAIN, Serine proteases, Elastases, HNE(Human Neutrophil Elastase), Component Reports
وصف الملف: text/html
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6Electronic Resource
المصدر: DTIC AND NTIS