-
1Academic Journal
المؤلفون: Raghunath G.V, M.S Veena, Suresh Janadri
المصدر: Journal of Ayurveda and Integrated Medical Sciences; Vol. 9 No. 2 (2024): FEBRUARY; 48 - 61 ; 2456-3110
مصطلحات موضوعية: HFD- High fat diet, PVK-Panchavalkala, Atorvastatin, Hyperlipidemia, AE-Aqueous extract, EE- Ethanolic extract, Anti hyperlipidemic
وصف الملف: application/pdf; text/html; text/xml
-
2Academic Journal
المؤلفون: Eman Kolieb, Shymaa Ahmed Maher, Mohammed Nader Shalaby, Amnah Mohammed Alsuhaibani, Afaf Alharthi, Wael A. Hassan, Karima El-Sayed
المصدر: International Journal of Environmental Research and Public Health; Volume 19; Issue 21; Pages: 13740
مصطلحات موضوعية: HFD: (high-fat diet), obesity, Exercise Physiology, Sports Exercise, Swimming Exercise Vit D: (vitamin D), FATP4: (fatty acid transport protein 4), TLR4: (Toll-like receptor 4 antibodies), T2D: (type 2 diabetes)
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Health Behavior, Chronic Disease and Health Promotion; https://dx.doi.org/10.3390/ijerph192113740
-
3Academic Journal
المؤلفون: Marcelin, Geneviève, da Cunha, Carla, Gamblin, Camille, Suffee, Nadine, Rouault, Christine, Leclerc, Arnaud, Lacombe, Amélie, Sokolovska, Nataliya, Gautier, Emmanuel, Clément, Karine, Dugail, Isabelle
المساهمون: Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition CHU Pitié Salpêtrière (IHU ICAN), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), Funding from the French National Agency of Research (ANR) is acknowledged and includes support from RHU collaborative grant CARMMA 15-RHUS-0003 , from the Institute of Cardiometabolism and Nutrition (reference ANR-10-IAHU-05, to AL), ANR-14-CE12-0017-01 LIPOCAMD and ANR CAPTOR (ANR-17-CE14-0009). GM 615 and KC also received funds from AFERO, EFSD-Novo Nordisk, and SFD to support for salaries and consumables., ANR-10-IAHU-0005,ICAN,Institut de Cardiologie-Métabolisme-Nutrition(2010), ANR-14-CE12-0017,LIPOCAMD,LIPA, une nouvelle cible thérapeutique pour le traitement des maladies cardiométaboliques(2014), ANR-17-CE14-0009,CAPTOR,Contrôler la fonction des progéniteurs du tissu adipeux pour améliorer les désordres métaboliques de l'obésité(2017)
المصدر: ISSN: 1554-8627.
مصطلحات موضوعية: ECM: extracellular matrix, EpiAT: epididymal adipose tissue, GTF2IRD1: 25 general transcription factor II I repeat domain-containing 1, HFD: high-fat diet, KO: knockout, OvAT: ovarian adipose tissue, PDGFR: platelet derived growth factor receptor, ScAT: subcutaneous adipose tissue, subcutaneous adipose tissue, obesity, TGF-BMP: transforming growth factor-bone morphogenic protein ARTICLE HISTORY KEYWORDS ATG7, fibrosis, collagen, chloroquine, extracellular matrix, Abbreviations: CQ: chloroquine, MESH: Adipose Tissue, Brown, MESH: Diet, High-Fat, MESH: Extracellular Matrix, MESH: Heart Atria, MESH: Female, MESH: Fibrosis, MESH: Male, MESH: Mice, Inbred C57BL, MESH: MicroRNAs, MESH: Muscle Proteins, MESH: Promoter Regions
Relation: info:eu-repo/semantics/altIdentifier/pmid/31992125; PUBMED: 31992125
-
4
المؤلفون: Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
المصدر: Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: HFD, high-fat diet, Cys, cysteine, cGAS, cyclic GMP–AMP synthase, Review, Poly: I.C, polyinosinic-polycytidylic acid, SAVI, STING-associated vasculopathy with onset in infancy, Bioinformatics, PPI, protein–protein interface, TRAF6, tumor necrosis factor receptor-associated factor 6, TREX1, three prime repair exonuclease 1, STIM1, stromal interaction molecule 1, 0302 clinical medicine, AA, amino acids, GTP, guanosine triphosphate, MLKL, mixed lineage kinase domain-like protein, ICAM-1, intracellular adhesion molecule 1, Medicine, PDE3B/4, phosphodiesterase-3B/4, General Pharmacology, Toxicology and Pharmaceutics, IKK, IκB kinase, NF-κB, nuclear factor-kappa B, cGAMP, 2′,3′-cyclic GMP–AMP, NLRP3, NOD-, LRR- and pyrin domain-containing protein 3, 0303 health sciences, dsDNA, double-stranded DNA, TFAM, mitochondrial transcription factor A, Fatty liver, Damage-associated molecular patterns, IFNIC, interferon-inducible cells, CTD, C-terminal domain, Mitochondria, Crosstalk (biology), Cardiovascular diseases, SNPs, single nucleotide polymorphisms, 030220 oncology & carcinogenesis, Stimulator of interferon genes, AAD, aortic aneurysm and dissection, MI, myocardial infarction, IFNAR, interferon receptors, ER stress, CVDs, cardiovascular diseases, NASH, nonalcoholic steatohepatitis, Intracellular, CDG, c-di-GMP, NTase, nucleotidyltransferase, ATP, adenosine triphosphate, Ser, serine, mTOR, mammalian target of rapamycin, RM1-950, STING, stimulator of interferon genes, hSTING, human stimulator of interferon genes, AKT, protein kinase B, CDNs, cyclic dinucleotides, TLR, Toll-like receptors, ER, endoplasmic reticulum, 03 medical and health sciences, LBD, ligand-binding pocket, ROS, reactive oxygen species, YAP1, Yes-associated protein 1, IFN, interferon, ISGs, IRF-3-dependent interferon-stimulated genes, DAMPs, danger-associated molecular patterns, IFN-I, type 1 interferon, 030304 developmental biology, Inflammation, Ang II, angiotensin II, TNFα, tumor necrosis factor-alpha, business.industry, IRF3, interferon regulatory factor 3, CTT, C-terminal tail, Autophagy, TAK1, transforming growth factor β-activated kinase 1, Metabolic diseases, medicine.disease, HAQ, R71H-G230A-R293Q, IL, interleukin, mtDNA, mitochondrial DNA, AMPK, AMP-activated protein kinase, Sting, Apoptosis, TBK1, TANK-binding kinase 1, CBD, C-binding domain, LPS, lipopolysaccharides, NO2-FA, nitro-fatty acids, PKA, protein kinase A, NAFLD, nonalcoholic fatty liver disease, Therapeutics. Pharmacology, DsbA-L, disulfide-bond A oxidoreductase-like protein, business, Homeostasis, MST1, mammalian Ste20-like kinases 1, TM, transmembrane, STING, cGAS
-
5
المؤلفون: Banrida Wahlang, Monika Thapa, Michael L. Merchant, Jian Jin, Sudhir Srivastava, Josiah E. Hardesty, Russell A. Prough, Shesh N. Rai, Matthew C. Cave, Kimberly Z. Head
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: WT, wild type, TAT, tyrosine aminotransferase, PCB126, AHR, IGF1, insulin-like growth factor 1, PCB, polychlorinated biphenyl, Blood lipids, FGF21, fibroblast growth factor 21, miR, microRNA, Pheromones, AHR, aryl hydrocarbon receptor, AUC, area under the curve, Liver disease, HFD, high fat diet, AST, aspartate transaminase, LDL, low-density lipoprotein, VLDL, very low-density lipoprotein, Environmental liver disease, General Pharmacology, Toxicology and Pharmaceutics, Receptor, MUP, major urinary protein, ANOVA, analysis of variance, NFKBIA, nuclear factor kappa-inhibitor alpha, PNPLA3, patatin-like phospholipase domain-containing protein 3, biology, ZFP125, zinc finger protein 125, PXR, pregnane-xenobiotic receptor, MCP-1, monocyte chemoattractant protein-1, respiratory system, EPF, enrichment by protein function, IL-6, interleukin 6, nHDLc, non-HDL cholesterol, IPF, interaction by protein function, PAI-1, plasminogen activator inhibitor-1, PLIN2, perilipin-2, Proteome, CYP, cytochrome P450, Original Article, CAR, constitutive androstane receptor, SGK1, serum/glucocorticoid regulated kinase, NAFLD, non-alcoholic fatty liver disease, medicine.medical_specialty, FDR, false discovery rate, ALT, alanine transaminase, Endocrine disruption, HDL, high-density lipoprotein, H&E, hematoxylin-eosin, RM1-950, CD36, cluster of differentiation 36, Perilipin-2, Internal medicine, medicine, Nonalcoholic fatty liver disease, Pheromone binding, GO, gene ontology, TASH, toxicant-associated steatohepatitis, PPARα, peroxisome proliferator-activated receptor alpha, TAFLD, toxicant-associated fatty liver disease, TMT, tandem mass tag, medicine.disease, Aryl hydrocarbon receptor, Insulin receptor, Endocrinology, biology.protein, GCR, glucocorticoid receptor, Therapeutics. Pharmacology, Steatosis
-
6
المؤلفون: Ying Han, Xintong Zhang, Wei Huang, Zhonggao Gao, Mingji Jin
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1789-1812 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: SLC, solute carrier, Bioavailability, AMI, amiodarone, MPA, mycophenolic acid, TLCA, taurolithocholate, ASP, amisulpride, RA, rheumatoid arthritis, Review, NRs, nitroreductases, MDR1, multidrug resistance gene 1, NaGC, sodium glycholate, MATEs, multidrug and toxin extrusion proteins, NMEs, new molecular entities, 0302 clinical medicine, HFD, high fat diet, P-gp, P-glycoprotein, ACS, amphipathic chitosan derivative, Medicine, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, 0303 health sciences, Gastrointestinal tract, IBD, inflammatory bowel disease, pKa, dissociation constant, RBC, red blood cell, FA, folate, OATs, organic anion transporters, 030220 oncology & carcinogenesis, MKC, monoketocholic acid, the GI tract, the gastrointestinal tract, AQP4, aquaporin 4, OCTNs, organic zwitterion/cation, T2D, type 2 diabetes, Gut microbiota, RM1-950, WHO, World Health Organization, 03 medical and health sciences, EcN, Escherichia coli Nissle 1917, Drug Transport Process, BDEPT, the bacteria-directed enzyme prodrug therapy, BCS, biopharmaceutics classification system, NEC, necrotizing enterocolitis, DRPs, digoxin reduction products, NaDC, sodium deoxycholate, Probiotics, CPP, cell-penetrating peptide, OCTs, organic cation transporters, TDCA, taurodeoxycholate, cgr operon, cardiac glycoside reductase operon, RA - Rheumatoid arthritis, DCA, deoxycholic acid, AA, ascorbic acid, BBR, berberine, Personalized medicine, BDDCS, the biopharmaceutics drug disposition classification system, SSZ, sulfasalazine, UDC, ursodeoxycholic acid, PPIs, proton pump inhibitors, BCRP, breast cancer resistance protein, CS, chitosan, Gut flora, Bioinformatics, PD, Parkinson's disease, SLN, solid lipid nanoparticle, SGLT-1, sodium-coupled glucose transporter 1, Oral administration, MRP2, multidrug resistance-associated protein 2, FAO, Food and Agriculture Organization of the United Nations, SVCT-1/2, the sodium-dependent vitamin C transporter-1/2, an OTC drug, an over-the-counter drug, CA, cholic acid, biology, ABC, ATP-binding cassette, T1DM, type 1 diabetes mellitus, NSAIDs, non-steroidal anti-inflammatory drugs, AR, azoreductase, GCDC, glycochenodeoxycholate, Drug delivery, GL, glycyrrhizic acid, PT, pectin, LPS, lipopolysaccharide, TME, the tumor microenvironment, T1D, type 1 diabetes, TCDC, taurochenodeoxycholate, Oral drugs, MDR1a, multidrug resistance protein-1a, SCFAs, short-chain fatty acids, CDCA, chenodeoxycholic acid, 030304 developmental biology, business.industry, dhBBR, dihydroberberine, biology.organism_classification, HTC, hematocrit, PWSDs, poorly water-soluble drugs, Colon-specific drug delivery system, stomatognathic diseases, SP, sulfapyridine, 5-ASA, 5-aminosalicylic acid, BSH, bile salt hydrolase, TCA, taurocholate, Therapeutics. Pharmacology, business
-
7
المؤلفون: Zhengcai Ju, Lin-shan Jiang, Xunjiang Wang, Wendong Huang, Zhengtao Wang, Siming Sun, Eryun Zhang, Lili Ding, Tong Tian, Qiaoling Yang, Li Yang, Yangmeng Wang, Yingbo Yang
المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1541-1554 (2021)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: eWAT, epididymal white adipose tissue, Wt, wild-type, Metabolic disorders, Adipose tissue, Ft1, notoginsenoside Ft1, AUC, area under the curve, iWAT, inguinal white adipose tissue, 0302 clinical medicine, HFD, high fat diet, General Pharmacology, Toxicology and Pharmaceutics, Receptor, ANOVA, analysis of variance, 0303 health sciences, Bile acid, Chemistry, TGR5, GLP-1, glucagon-like peptide-1, Tgr5, membrane-bound G protein-coupled receptor, G protein-coupled bile acid receptor, cAMP, adenosine 3′,5′ cyclic monophosphate, medicine.anatomical_structure, FXR, 030220 oncology & carcinogenesis, GTT, glucose tolerance test, Original Article, Agonist, medicine.medical_specialty, medicine.drug_class, Ileum, RM1-950, 03 medical and health sciences, Insulin resistance, Ucp, uncoupling protein, Internal medicine, Fxr, nuclear farnesoid X receptor, medicine, Lipolysis, Obesity, ITT, insulin tolerance test, 030304 developmental biology, KO, knockout, BAs, bile acids, DIO, diet-induced obesity, medicine.disease, Bile acids, FGF, fibroblast growth factor, BAT, brown adipose tissue, Endocrinology, Therapeutics. Pharmacology, GLP-1, Notoginsenoside Ft1
-
8
المؤلفون: Noha M. Abogresha, Ghada Abdel Kader, Sahar M Greish, Dalia A. Eltamany, Hanaa S. Sallam, Eman Z. Abdelaziz
المصدر: Saudi Journal of Biological Sciences, Vol 28, Iss 5, Pp 2956-2963 (2021)
Saudi Journal of Biological Sciencesمصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, HFD, high-fat diet, GSH, reduced glutathione, Blood lipids, medicine.disease_cause, 01 natural sciences, Moringa, chemistry.chemical_compound, Lycopene, LDL, low-density lipoprotein, VLDL, very low-density lipoprotein, Biology (General), Testosterone, medicine.diagnostic_test, HMG-Co-A, β-Hydroxy β-methylglutaryl-CoA, NE, Eosin-Nigrosin, LH, Luteinizing hormone, iNOS, inducible nitric oxide synthase, Original Article, General Agricultural and Biological Sciences, IHC, immunohistochemistry, LY, lycopene, medicine.medical_specialty, QH301-705.5, HDL, high-density lipoprotein, 03 medical and health sciences, ROS, reactive oxygen species, PBS, phosphate buffered saline, SOD, superoxide dismutase, Internal medicine, medicine, Obesity, MDA, malondialdehyde, business.industry, RC, regular chow, MO, moringa, Sperm, TC, total cholesterol, Fertility, 030104 developmental biology, Endocrinology, chemistry, Oxidative stress, H&E, hematoxylin and eosin, FSH, follicle-stimulating hormone, Lipid profile, business, Corn oil, 010606 plant biology & botany
-
9
المؤلفون: Yuxiao Liu, Xiaozhen Dai, Xiao-Lin Liu, Aoyuan Cui, Feng Shen, Feng-Zhi Xin, Weitong Su, Jian-Gao Fan, Yamei Han, Ze-Hua Zhao, Feifei Zhang, Yaqian Xue, Yu Li, Genxiang Cai, Zhengshuai Liu, Zi-Xuan Wang, Qin Pan, Jinyun Bai, Zhimin Hu, Tian-Yi Ren, Fengguang Ma, Da Zhou
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)مصطلحات موضوعية: Male, 0301 basic medicine, HFD, high-fat diet, Hepatic Lipogenesis, RC799-869, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, GST, glutathione S-transferase, Mice, chemistry.chemical_compound, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Insulin, Phosphorylation, Insig, insulin-induced gene, Original Research, Chemistry, Kinase, Gastroenterology, Sodium butyrate, Diseases of the digestive system. Gastroenterology, 030211 gastroenterology & hepatology, medicine.medical_specialty, Insulin-Induced Gene, LKB1, ATP, adenosine triphosphate, MAP Kinase Signaling System, NaB, sodium butyrate, Butyrate, Diet, High-Fat, Models, Biological, 03 medical and health sciences, LKB1, liver kinase B1, NAFLD, Internal medicine, PYY, peptide YY, medicine, Animals, Humans, GLP-1, glucagon-like peptide 1, Protein kinase A, Hepatology, Lipogenesis, AMPK, Lipid Metabolism, medicine.disease, Sodium Butyrate, AMPK, AMP-activated protein kinase, Disease Models, Animal, 030104 developmental biology, Endocrinology, Gene Expression Regulation, AMP, adenosine monophosphate, Dietary Supplements, Hepatocytes, Butyric Acid, NAFLD, nonalcoholic fatty liver disease, Liver function, Steatosis
-
10
المؤلفون: Zhi-Yuan Wu, Jin-Song Bian, Xiao-Wei Nie, Hai-Jian Sun, Xin-Yu Wang
المصدر: Journal of Advanced Research, Vol 27, Iss, Pp 127-135 (2021)
Journal of Advanced Researchمصطلحات موضوعية: 0301 basic medicine, Steatosis, STAT3, signal transducer and activator of transcription 3, Regulator, HO-1, heme oxygenase 1, SPRC, S-propargyl-cysteine, NaHS, sodium hydrosulfide, Liver disease, 0302 clinical medicine, HFD, high fat diet, PPG, propargylglycine, Fibrosis, MMP-2, matrix metalloproteinase 2, NF-κB, nuclear factor-kappa B, Cancer, lcsh:R5-920, Multidisciplinary, Hydrogen sulfide, CAT, cysteine aminotransferase, PI3K, phosphatidylinositol 3-kinase, CBS, cystathione β-synthase, FAS, fatty acid synthase, CSE, cystathione γ-lyase, DAO, D-amino acid oxidase, CO, carbon monoxide, COX-2, cyclooxygenase-2, 030220 oncology & carcinogenesis, NAFLD, non-alcoholic fatty liver diseases, AGTR1, angiotensin II type 1 receptor, CX3CR1, chemokine CX3C motif receptor 1, lcsh:Medicine (General), Liver cancer, NASH, nonalcoholic steatohepatitis, Nrf2, nuclear factor erythroid2-related factor 2, 3-MST, 3-mercaptopyruvate sulfurtransferase, Sulfurtransferase, mTOR, mammalian target of rapamycin, Article, SAC, S-allyl-cysteine, H2S, hydrogen sulfide, 03 medical and health sciences, VLDL, very low density lipoprotein, NADH, nicotinamide adenine dinucleotide, medicine, lcsh:Science (General), ComputingMethodologies_COMPUTERGRAPHICS, PTEN, phosphatase and tensin homolog deleted on chromosome ten, 3-MP, 3-mercaptopyruvate, business.industry, ERK, extracellular regulated protein kinases, IR, ischemia/reperfusion, NADPH, nicotinamide adenine dinucleotide phosphate, equipment and supplies, medicine.disease, EGFR, epidermal growth factor receptor, AMPK, AMP-activated protein kinase, 030104 developmental biology, Akt, protein kinase B, Cancer research, DATS, Diallyl trisulfide, PLP, pyridoxal 5′-phosphate, Hepatic fibrosis, business, lcsh:Q1-390
-
11
المؤلفون: Yatrik M. Shah, Shogo Takahashi, Sadeesh K. Ramakrishnan, Raja Gopal Reddy Mooli, Frank J. Gonzalez, Sumeet Solanki, Jessica Rodriguez
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 585-597 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, HFD, high-fat diet, Fgf21, fibroblast growth factor 21, β-Oxidation, RC799-869, VHL, Von Hippel-Lindau, PPARα, Liver disease, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Cyp4a10 and Cyp4a14, cytochrome P450, family 4, subfamily a, polypeptide 10 and 14, Nonalcoholic fatty liver disease, Hypoxia, Cells, Cultured, Original Research, Mice, Knockout, chemistry.chemical_classification, Chemistry, Fatty Acids, Fatty liver, Gastroenterology, Diseases of the digestive system. Gastroenterology, Postprandial Period, MEK, ERK, medicine.anatomical_structure, Liver, CD36, cluster of differenatiation 36, Hepatocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, Oxidation-Reduction, medicine.medical_specialty, MAP Kinase Signaling System, Acot1, acyl-CoA thioesterase 1, PPARα, peroxisome proliferator activated receptor alpha, HIF1α and HIF2α, hypoxia inducing factor 1 and 2 alpha, 03 medical and health sciences, Internal medicine, Genetic model, Autophagy, medicine, Animals, HIF, PPAR alpha, RNA, Messenger, Mitogen-Activated Protein Kinase Kinases, Hepatology, Cpt1a, carnitine palmitoyltransferase 1, Fatty acid, Acox1, acyl-coenzyme A oxidase, Feeding Behavior, Lipid Metabolism, medicine.disease, WT, wild-type, Cyclic AMP-Dependent Protein Kinases, Fatty Liver, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Hepatocytes, PKA, protein kinase A, NAFLD, nonalcoholic fatty liver disease, Steatosis
-
12
المؤلفون: Irina A. Kirpich, Banrida Wahlang, Nicholas C. Alexander, Xiaohong Li, Matthew C. Cave, Eric C. Rouchka
المصدر: Toxicology Reports, Vol 8, Iss, Pp 536-547 (2021)
Toxicology Reportsمصطلحات موضوعية: Tjp1, tight junction protein 1, Health, Toxicology and Mutagenesis, RER, respiratory exchange rate, ACHS, anniston community healthy survey, Camp, cathelicidin anti-microbial peptide, 010501 environmental sciences, Toxicology, 01 natural sciences, chemistry.chemical_compound, 0302 clinical medicine, HFD, high fat diet, Tnfa, tumor necrosis factor, HOMA, homeostasis model assessment, RA1190-1270, Cldn, claudin, Constitutive androstane receptor, Aroclor1260, PCBs, Pck1, phosphoenolpyruvate carboxykinase 1, Pregnane X receptor, Fatty liver, Cdh5, adhesion molecule VE-cadherin, Regular Article, PXR, pregnane-xenobiotic receptor, Muc, mucin, Gut-liver, Knockout mouse, CAR, constitutive androstane receptor, NASH, nonalcoholic steatohepatitis, AhR, arylhydrocarbon receptor, medicine.medical_specialty, Fasn, fatty acid synthase, Biology, digestive system, Ppara, peroxisome-proliferator activated receptor alpha, 03 medical and health sciences, PCBs, polychlorinated biphenyls, Tff3, trefoil factor 3, Internal medicine, NAFLD, OTU, operational taxonomic unit, medicine, WT, wildtype, Microbiome, IBD, inflammatory bowel diseases, Gene knockout, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, TASH, toxicant-associated steatohepatitis, Fgf15, fibroblast growth factor 15, medicine.disease, LEfSe, linear discriminant analysis effect size, digestive system diseases, Ocln, occludin, Endocrinology, TASH, chemistry, Toxicology. Poisons, NAFLD, nonalcoholic fatty liver disease, Reg3g, regenerating islet-derived protein 3-gamma, Steatohepatitis, human activities, LDA, linear discriminant analysis, 030217 neurology & neurosurgery, Toxicant
-
13
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1177-1197 (2021)مصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Antioxidant, Colorectal cancer, medicine.medical_treatment, Review, Inflammatory bowel disease, Antioxidants, 0302 clinical medicine, AOM, azoxymethane, CAC, colitis-associated colon cancer, DSS, dextran sodium sulfate, IBD, inflammatory bowel disease, vitC, vitamin C, GSTTT1, glutathione-S-transferase theta 1, Gastroenterology, 8-oxoG, 8-oxo-7,8-dihydro-2′-deoxyguanosine, Colitis, 3. Good health, NAC, N-acetylcysteine, NOX, nicotinamide adenine dinucleotide phosphate oxidase, CRC, colorectal cancer, 030211 gastroenterology & hepatology, medicine.symptom, DNA damage, Inflammation, Context (language use), MMR, mismatch repair, H2O2, hydrogen peroxidase, vitE, vitamin E, 03 medical and health sciences, ROS, reactive oxygen species, mtROS, mitochondrial ROS, SOD, superoxide dismutase, Gpx, glutathione peroxidase, GST, glutathione-S-transferase, medicine, PRDX, peroxiredoxin, RNI, reactive nitrogen intermediaries, Animals, Humans, lcsh:RC799-869, Colorectal Cancer, DUOX2, dual oxidase 2, Hepatology, business.industry, Inflammatory Bowel Disease, medicine.disease, AT1, angiotensin II type 1, digestive system diseases, Review article, O2•-, superoxide, UC, ulcerative colitis, 030104 developmental biology, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, CAT, catalase, Colitis-Associated Neoplasms, business, DNA Damage
-
14
المؤلفون: Chang Hwa Jung, Hyunjung Lee, Hyo-Deok Seo, Jiyun Ahn, Young In Kim, Tae-Youl Ha, Seung Yeon Ha
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1201-1213 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, Catechols, Gene Expression, ACC, acetyl-CoA carboxylase, RC799-869, Pathogenesis, Mice, 0302 clinical medicine, Genes, Reporter, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, miRNA, microRNA, Original Research, chemistry.chemical_classification, Chemistry, Fatty liver, Gastroenterology, MicroRNA, 1-Acylglycerol-3-Phosphate O-Acyltransferase, Diseases of the digestive system. Gastroenterology, mRNA, messenger RNA, ChIP, chromatin immunoprecipitation, Hepatocyte nuclear factors, HF, high-fat diet–fed group, UTR, untranslated region, Hepatocyte Nuclear Factor 4, 030211 gastroenterology & hepatology, RNA Interference, Fatty Alcohols, Intracellular, medicine.medical_specialty, TAG, triacylglycerol, DNL, de novo lipogenesis, HNF4α, hepatocyte nuclear factor 4α, 6-G, 6-gingerol, GPAT1, 03 medical and health sciences, Structure-Activity Relationship, cDNA, complementary DNA, GPAT, glycerol-3-phosphate acyltransferase, Internal medicine, NAFLD, microRNA, FFA, free fatty acid, medicine, Animals, Humans, HNF4α, Hepatology, DARTS, drug-affinity–responsive target stability, TLDA, TaqMan low-density arrays, Fatty acid, medicine.disease, Lipid Metabolism, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Endocrinology, Gene Expression Regulation, LysoPA, lysophosphatidic acid, NAFLD, nonalcoholic fatty liver disease, Steatosis, 6-gingerol
-
15
المؤلفون: Tetsuo Takehara, Tomohide Tatsumi, Ryotaro Sakamori, Kumiko Shirai, Sadatsugu Sakane, Yuki Makino, Kenji Fukumoto, Takahiro Kodama, Yuta Myojin, Hayato Hikita, Youichi Sasaki, Ryoko Yamada, Yuki Tahata, Naoki Mizutani, Shinnosuke Kudo
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1683-1699 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: eWAT, epididymal white adipose tissue, HFD, high-fat diet, medicine.medical_specialty, Adipose tissue, Nonalcoholic Steatohepatitis, Inflammation, mTOR, mammalian target of rapamycin, RC799-869, White adipose tissue, iWAT, inguinal white adipose tissue, PCR, polymerase chain reaction, Non-alcoholic Fatty Liver Disease, Fibrosis, ALT, alanine aminotransferase, 4-HNE, 4-hydroxynonenal, Internal medicine, Lipid droplet, Nonalcoholic fatty liver disease, Autophagy, medicine, Humans, Original Research, TNF, tumor necrosis factor, KO, knockout, Hepatology, ND, normal diet, business.industry, Intracellular Signaling Peptides and Proteins, Gastroenterology, nutritional and metabolic diseases, Diseases of the digestive system. Gastroenterology, medicine.disease, IL, interleukin, NEFA, nonesterified fatty acid, Endocrinology, Adipose Tissue, NAFLD, nonalcoholic fatty liver disease, FFAs, free fatty acids, medicine.symptom, Steatosis, business, NASH, nonalcoholic steatohepatitis, TUNEL, deoxyuride-5′-triphosphate biotin nick end labeling
-
16
المؤلفون: Marica Cariello, Antonio Moschetta, Elena Piccinin
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1519-1539 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Peroxisome Proliferator-Activated Receptors, Nuclear Receptors, Receptors, Cytoplasmic and Nuclear, Review, AST, aspartate aminotransferase, RC799-869, FLINT, FXR ligand obeticholic acid for noncirrhotic, nonalcoholic steatohepatitis trial, SHP, small heterodimer partner, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, CCl4, carbon tetrachloride, MUFA, monounsaturated fatty acid, PNPLA3, polymorphisms in patatin-like phospholipase 3, Receptor, NOS, nitric oxide synthase, Liver X Receptors, Peroxisome Proliferator Activated Receptors (PPARs), CA, cholic acid, TNF, tumor necrosis factor, Bile acid, Nonalcoholic Steatohepatitis (NASH), Gastroenterology, SREBP1c, sterol regulatory element-binding protein 1c, WAT, white adipose tissue, NR, nuclear receptor, Diseases of the digestive system. Gastroenterology, Lipids, HSC, hepatic stellate cell, REGENERATE, Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment, OCA, obeticholic acid, NAFL, nonalcoholic fatty liver, BA, bile acid, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, NASH, nonalcoholic steatohepatitis, Metabolic Networks and Pathways, TLR, Toll-like receptor, ATP, adenosine triphosphate, Oxysterol, medicine.drug_class, HDL, high-density lipoprotein, Biology, CYP7A1, cytochrome P450 7A1, Farnesoid X Receptor (FXR), digestive system, APO-E2, apolipoprotein-E2, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, ALT, alanine aminotransferase, Liver X Receptor (LXR), medicine, Animals, Humans, Liver X receptor, SCD1, stearoyl-CoA desaturase 1, PPAR, peroxisome proliferator activated receptor, Hepatology, MCDD, methionine- and choline-deficient diet, medicine.disease, digestive system diseases, FGF, fibroblast growth factor, VLDLR, very-low-density lipoprotein receptor, 030104 developmental biology, CoA, Coenzyme A, Nuclear receptor, Gene Expression Regulation, Cancer research, Farnesoid X receptor, NAFLD, nonalcoholic fatty liver disease, Steatohepatitis, LXR, liver X receptor
-
17Academic Journal
المؤلفون: G. S. Tapia, D. González-Mañán, A. D’Espessailles, C. G. Dossi
المصدر: Grasas y Aceites, Vol 67, Iss 2, Pp e134-e134 (2016)
مصطلحات موضوعية: acox (acyl coenzyme a oxidase), ap-1(activating protein 1), cat-1 (carnitine acyl transferase i), hfd (high fat diet), nafld (non-alcoholic fatty liver disease), n-3 lcpufa (n-3 long chain polyunsaturated fatty acid), reversion, Nutrition. Foods and food supply, TX341-641
وصف الملف: electronic resource
-
18
المؤلفون: Di Zhao, Xuemeng Liu, Junhui Xing, Jie-Lei Zhang, Pengcheng Li, Jianwu Jiang, Yanzhou Zhang
المصدر: Journal of Advanced Research, Vol 26, Iss, Pp 123-135 (2020)
Journal of Advanced Researchمصطلحات موضوعية: 0301 basic medicine, CAD, coronary artery disease, RIP, RNA binding protein immunoprecipitation, lncRNAs, long noncoding RNAs, ICAM-1, intercellular adhesion molecule-1, HCAECs, human coronary artery endothelial cells, USF1, upstream stimulatory factor 1, TNF-α, tumor necrosis factor-α, DMEM, Dulbecco’s modified Eagle’s medium, VCAM-1, vascular cell adhesion molecule 1, 0302 clinical medicine, HFD, high fat diet, ChIP, Chromatin immunoprecipitation, LDL, low-density lipoprotein, GAPDH, Glyceraldehyde-3-phosphate dehydrogenase, SMCs, smooth muscle cells, RT-qPCR, reverse transcription quantitative polymerase chain reaction, IL-6, interleukin-6, Gene knockdown, lcsh:R5-920, Multidisciplinary, ND, normal diet, Cell adhesion molecule, Chemistry, sh, short hairpin RNA, MCP-1, monocyte chemoattractant protein-1, 030220 oncology & carcinogenesis, HE, Hematoxylin-eosin, Tumor necrosis factor alpha, medicine.symptom, Hypoxia-inducible factor 1 alpha-antisense RNA 2, lcsh:Medicine (General), ECs, endothelial cells, ATF2, activating transcription factor 2, IL-1β, interleukin-1β, Intercellular Adhesion Molecule-1, IgG, immunoglobulin G, Inflammation, Article, 03 medical and health sciences, CCK-8, cell counting kit-8, Activating transcription factor, PBS, phosphate buffered saline, Downregulation and upregulation, ox-LDL, oxidized-low-density lipoprotein, ELISA, enzyme linked immunosorbent assay, medicine, Gene silencing, Upstream transcription factor 1, lcsh:Science (General), Transcription factor, HIF1A-AS2, hypoxia-inducible factor 1 alpha-antisense RNA 2, ATCC, American Type Culture Collection, Atherosclerosis, si-NC, small interfering RNA-negative control, 030104 developmental biology, Cancer research, Long noncoding RNA, lcsh:Q1-390
-
19
المؤلفون: Angeliki Lykoudi, Alaa F. Bakr, Mariam R. Habil, Raúl A. Salazar-González, Kyung U. Hong, Shirish Barve, Gavin E. Arteel, Kennedy M. Walls, Smita Ghare, Mark A. Doll, David W. Hein
المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 1319-1330 (2020)مصطلحات موضوعية: medicine.medical_specialty, HFD, high-fat diet, obesity, Health, Toxicology and Mutagenesis, OGTT, oral glucose tolerance test, invAUC, inverse area under the curve, Congenic, 010501 environmental sciences, Toxicology, 01 natural sciences, metabolic syndrome, 03 medical and health sciences, chemistry.chemical_compound, AUC, area under the curve, 0302 clinical medicine, Insulin resistance, lcsh:RA1190-1270, Internal medicine, insulin resistance, Genotype, medicine, GWAS, genome-wide association study, 0105 earth and related environmental sciences, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, ITT, insulin tolerance test, Arylamine N-acetyltransferase, Triglyceride, business.industry, dyslipidemia, Regular Article, medicine.disease, Obesity, TC, total cholesterol, Endocrinology, chemistry, CD, control diet, Metabolic syndrome, NAT, arylamine N-acetyltransferase, business, diet, 030217 neurology & neurosurgery, Dyslipidemia
-
20
المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 4, Pp 582-602 (2020)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: HFD, high-fat diet, Monoacylglycerol lipases, THL, tetrahydrolipstatin, AA, arachidonic acid, SDS-PAGE, sodium dodecyl sulphate polyacrylamide gel electrophoresis, Review, Pharmacology, PD, Parkinson's disease, chemistry.chemical_compound, OCT2, organic cation transporter 2, 0302 clinical medicine, Neuroinflammation, MAGL, monoacylglycerol lipase, P-gp, P-glycoprotein, PA, phosphatidic acid, General Pharmacology, Toxicology and Pharmaceutics, Cancer, 0303 health sciences, ABPP, activity-based protein profiling, Drug discovery, FP-Rh, fluorophosphonate-rhodamine, Chemistry, CC-ABPP, click chemistry activity-based protein profiling, Serine hydrolase, Metabolic syndrome, Endocannabinoid system, PGs, prostaglandins, NHS, N-hydroxysuccinimidyl, Arachidonic acid, 030220 oncology & carcinogenesis, AD, Alzheimer's disease, FFAs, free fatty acids, 2-Arachidaoylglycerol, 2-AG, 2-arachidonoyl glycerol, ABHD6 and ABHD12, α/β-hydrolase 6 and 12, FP, fluorophosphonate, PGE2, prostaglandin, CNS, central nervous system, PK, pharmacokinetic, PET, positron emission tomography, MS, multiple sclerosis, EAE, encephalomyelitis, 03 medical and health sciences, SAR, structure–activity relationship, 7-HCA, 7-hydroxycoumarinyl arachidonate, PLA2G7, phospholipase A2 group VII, SBDD, structure-based drug design, 2-OG, 2-oleoylglycerol, CB1R and CB2R, cannabinoid receptors, cPLA2, cytosolic phospholipase A2, BCRP, breast cancer resistant protein, 030304 developmental biology, MAGs, monoglycerides, EI, enzyme–inhibitor complex, FQ, fit quality, AEA, anandamide, lcsh:RM1-950, 4-NPA, 4-nitrophenylacetate, HFIP, hexafluoroisopropyl, Lipid metabolism, NAM, N-arachidonoyl maleimide, CFA, complete Freund's adjuvant, ABP, activity-based probes, LFD, low-fat diet, Monoacylglycerol lipase, FAAH, amide hydrolase, CYP, cytochrome P450 proteins, LC–MS, liquid chromatographic mass spectrometry, lcsh:Therapeutics. Pharmacology, Eicosanoid, DTT, dithiothreitol, DAGLs, diacylglycerol lipases, COX, cyclooxygenases, DAG, diacylglycerol