المؤلفون: Xiaohong Sang, Juan Wang, Jiao Zhou, Yan Xu, Jing An, Arieh Warshel, Ziwei Huang

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Pharmacology, Cancer, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, major therapeutic targets, could effectively induce, new alternative strategy, hek 293t cells, pro , cov ‑ 2, chemical strategy, viral infection, thus demonstrating, resistant mutants, proteins important, novel coronavirus, main protease, global pandemic, cells sars, biological characterization

Relation: https://figshare.com/articles/journal_contribution/A_Chemical_Strategy_for_the_Degradation_of_the_Main_Protease_of_SARS-CoV_2_in_Cells/24777412

الاتاحة: https://doi.org/10.1021/jacs.3c12678.s001
https://figshare.com/articles/journal_contribution/A_Chemical_Strategy_for_the_Degradation_of_the_Main_Protease_of_SARS-CoV_2_in_Cells/24777412

المؤلفون: Gregor Dekevic, Tobias Tertel, Lars Tasto, Deborah Schmidt, Bernd Giebel, Peter Czermak, Denise Salzig

المصدر: Viruses, Vol 15, Iss 2013, p 2013 (2023)

مصطلحات موضوعية: stirred-tank bioreactor (STR), HEK 293T cells, lPEI, Process Analytical Technology (PAT), design of experiments, IFCM, Microbiology, QR1-502

Relation: https://www.mdpi.com/1999-4915/15/10/2013; https://doaj.org/toc/1999-4915; https://doaj.org/article/601dcada36914762b028bbcbf0184c46

الاتاحة: https://doi.org/10.3390/v15102013
https://doaj.org/article/601dcada36914762b028bbcbf0184c46

المؤلفون: Zhe Liu, Fang Ma, Yujun Kang, Xiaoxia Liu

المصدر: PeerJ, Vol 10, p e13476 (2022)

مصطلحات موضوعية: Expression regulation, ssa-miR-301a-3p, hsp90b2, HEK 293T cells, Rainbow trout, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://peerj.com/articles/13476.pdf; https://peerj.com/articles/13476/; https://doaj.org/toc/2167-8359

URL الوصول: https://doaj.org/article/ba02d280499140e4831e0aca1b4d4624

المؤلفون: Hongyan An (1783111), Alexander Richardson (10508788), Poornima Rajasekariah (10508791), Ling Zhong (209116), Bentotage Samitha M. Fernando (10508794), Alexander Macmillan (1879951), Enrico Klotzsch (124184), Katherine Bryant (327726), Nadeem O. Kaakoush (192831), Nicodemus Tedla (327727)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Virology, Computational Biology, Chemical Sciences not elsewhere classified, Nuclear Leukocyte Immunoglobulin-li., displays neuro-regenerative functions, intracellular expression, Ewing sarcoma breakpoint region 1 p., host protein synthesis machinery, EWS, Extracellular LILRA 3, monomeric LILRA 3, leukocyte immunoglobulin-like receptor, LILRA 3-GFP HEK 293T cells, LILRA 3 proteins, Regulated Gene Expression, HEK 293T cells, transfected HEK 293T cells, LILRA 3

Relation: https://figshare.com/articles/journal_contribution/Nuclear_Leukocyte_Immunoglobulin-like_Receptor_A3_Is_Monomeric_and_Is_Involved_in_Multiple_Layers_of_Regulated_Gene_Expression_and_Translation/14350924

الاتاحة: https://doi.org/10.1021/acs.jproteome.0c00946.s001

المؤلفون: Jianrong Liu (532302), Ling Ma (107282), Chang Song (172416), Hui Xing (80421), Shan Cen (107285), Wenhan Lin (471132)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Pharmacology, Sociology, Immunology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, HIV virus infection, anti-HIV, strain SF 33, mode, photoaffinity baculiferin probes, marine sponge-derived polycyclic al., congener, 3.44 μ M, HEK 293T cells, Potential Target Protein DARS Bacul., IC 50, LC-MS, SAR, 2.80 μ M, data, target protein

Relation: https://figshare.com/articles/journal_contribution/Anti-HIV_Effects_of_Baculiferins_Are_Regulated_by_the_Potential_Target_Protein_DARS/15091098

الاتاحة: https://doi.org/10.1021/acschembio.1c00148.s002

المؤلفون: Abhishek Mondal (11197453), Javid Ahmad Malla (11197456), Harshad Paithankar (1625533), Shilpy Sharma (1638547), Jeetender Chugh (1625542), Pinaki Talukdar (1716736)

مصطلحات موضوعية: Biophysics, Biochemistry, Physiology, Pharmacology, Biotechnology, Evolutionary Biology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Pyridyl-Linked Benzimidazolyl Tauto., chloride ion recognition, pyridyl-linked benzimidazolyl hydra., Cooperative Protonation, transport efficiency, noncancerous HEK 293T cells, Viability assays, HCl cotransporters, HCl transport, HCl binding site, compound, 2 times, breast cancer MCF -7 cells, lysosome deacidification

Relation: https://figshare.com/articles/journal_contribution/A_Pyridyl-Linked_Benzimidazolyl_Tautomer_Facilitates_Prodigious_H_sup_sup_Cl_sup_sup_Symport_through_a_Cooperative_Protonation_and_Chloride_Ion_Recognition/15067267

الاتاحة: https://doi.org/10.1021/acs.orglett.1c02235.s001

المؤلفون: Qiushuang Sun (11202521), Qun Niu (151870), Yating Guo (9403369), Yu Zhuang (2824982), Xiaonan Li (340228), Jia Liu (41593), Ning Li (45258), Zhiyu Li (10983), Fang Huang (154302), Zhixia Qiu (5535824)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Cancer, Virology, Chemical Sciences not elsewhere classified, Novel Mechanism Mediating, attenuate lipid accumulation, plasma membrane citrate transporter, SLC 13A mitochondrial citrate carrier, hepatic lipid deposition, ACLY, Inhibiting SLC 13A, AMPK, Curcumin, OPA-stimulated HepG 2 cells, DNL, NAFLD, Cytoplasmic citrate flux, HepG 2 cells, 25A, HFHFD, SLC 13A, HEK 293T cells transfected, ATP-dependent citrate lyase

Relation: https://figshare.com/articles/journal_contribution/Regulation_on_Citrate_Influx_and_Metabolism_through_Inhibiting_SLC13A5_and_ACLY_A_Novel_Mechanism_Mediating_the_Therapeutic_Effects_of_Curcumin_on_NAFLD/15073493

الاتاحة: https://doi.org/10.1021/acs.jafc.1c03105.s001

المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells

Relation: https://figshare.com/articles/journal_contribution/Cignal_Reporter_Assay_used_to_measure_pathway_activity_and_their_associated_hallmark_pathways_/14902712

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009132.s010

المؤلفون: Alexis M. Thornton (11068403), Lishan Fang (10101825), April Lo (11068406), Maria McSharry (11068409), David Haan (11068412), Casey O’Brien (4671856), Alice H. Berger (11068415), Marios Giannakis (3564314), Angela N. Brooks (11068418)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Physiology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, RAS, RNF 43 R 117fs RNF 43 G 659fs, KRAS, eVIP 2 software, Additional eVIP Pathways analysis, expression-based variant impact phe., Western blot analysis, change-of-function mutation, G 659fs variants, RNF 43 WT, GOF, eVIP 2 method, GFP control cDNA, gene variants, RNF 43 WT function, gene variant function, decision tree-based algorithm, eVIP 2, RNF 43 G 659fs, HEK 293T cells

Relation: https://figshare.com/articles/journal_contribution/Reporter_assay_results_compared_with_eVIP_Pathways_and_GSEA_/14902715

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009132.s011

المؤلفون: Hiral M. Sanghavi (10873419), Sharmistha Majumdar (6427640)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Genetics, Molecular Biology, Physiology, Developmental Biology, Virology, Biological Sciences not elsewhere classified, Physical Sciences not elsewhere classified, protein interaction partners, Human THAP 9, oligomerization, amino-terminal DNA binding, THAP 9 Transposase, HEK 293T cells, hTHAP 9. Elucidating, form higher-order oligomeric states, Drosophila P element transposase, proximity ligation assays, DmTNP, hTHAP 9, region

Relation: https://figshare.com/articles/journal_contribution/Oligomerization_of_THAP9_Transposase_via_Amino-Terminal_Domains/14675481

الاتاحة: https://doi.org/10.1021/acs.biochem.1c00010.s001

المؤلفون: Hui-Chen Chang Foreman (10925057), Varvara Kirillov (8098547), Gabrielle Paniccia (10925059), Demetra Catalano (10925061), Trevor Andrunik (10925063), Swati Gupta (1340451), Laurie T. Krug (8098550), Yue Zhang (30585)

مصطلحات موضوعية: Medicine, Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, murine gammaherpesvirus 68, RNA-guided gene editing, virus production Epstein-Barr virus, Cas 9-gRNA editing, murine gammaherpesvirus 68 genome, animal model systems, Burkitt lymphoma cells, Cas 9, Cas 9-MHV gRNA components, KSHV, 20 B cell lines, Cas 9-gRNA system, HEK 293T cells, infection, Murine NIH 3T fibroblast cells, ORF, murine gammaherpesvirus genome, gene editing, CRISPR

Relation: https://figshare.com/articles/journal_contribution/The_original_blots_of_Fig_2B_and_original_gels_of_Figs_3A_3C_and_4B_as_indicated_/14735527

الاتاحة: https://doi.org/10.1371/journal.pone.0252313.s001

المؤلفون: Casimir Bamberger (378651), Sandra Pankow (160675), Salvador Martínez-Bartolomé (1234551), Michelle Ma (251764), Jolene Diedrich (10668759), Robert A. Rissman (7521480), John R. Yates (1234548)

مصطلحات موضوعية: Biophysics, Biochemistry, Neuroscience, Biotechnology, Ecology, Immunology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, 3 D structures, SHDB, CPP, mass spectrometry-based protein foo., Protein, 3 D proteome, hyperphosphorylated tau, Alzheimer, DLB, amyloid -β peptide, TUBB, survey, HEK 293T cells, covalent modification, 2645 lysine residues, postmortem brain samples, covalent protein painting, accessibility, reactivity, AD, lysine ε- amines

Relation: https://figshare.com/articles/journal_contribution/Protein_Footprinting_via_Covalent_Protein_Painting_Reveals_Structural_Changes_of_the_Proteome_in_Alzheimer_s_Disease/14449776

الاتاحة: https://doi.org/10.1021/acs.jproteome.0c00912.s001

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Turkey_test_of_significant_differences_between_tested_interaction_times_1_and_2_min_against_TAS1R2_receptor_/13757974

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s003

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/ANOVA_analysis_of_the_TAS1R2_interaction_/13757965

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s001

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Scheffe_test_of_comparisons_between_tested_samples_against_TAS1R2_receptor_/13757983

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s005

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Turkey_test_of_significant_differences_between_tested_dilutions_1_and_10x_against_TAS1R2_receptor_/13757980

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s004

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Scheffe_test_of_significant_differences_between_tested_dilutions_1_and_10x_against_TAS1R2_receptor_/13757992

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s007

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Scheffe_test_of_significant_differences_between_tested_interaction_times_1_and_2_min_against_TAS1R2_receptor_/13757989

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s006

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Turkey_test_of_comparisons_between_tested_samples_against_TAS2R3_receptor_/13758001

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s009

المؤلفون: Oskar Szczepaniak (7529444), Maria Jokiel (10113085), Kinga Stuper-Szablewska (7390760), Daria Szymanowska (6572672), Marcin Dziedziński (8141355), Joanna Kobus-Cisowska (6572669)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Sociology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- minute interaction, TAS 2R, Human TAS 2R receptors, Bacillus coagulans probiotic strains, antioxidant activity, Cornus mas, calcium release test, chocolate products, TAS 2R activity, TAS 2R receptors, transfected HEK 293T cells, cornelian, CFU

Relation: https://figshare.com/articles/journal_contribution/Scheffe_test_of_significant_differences_between_tested_tested_dilutions_1_and_10x_against_TAS2R3_receptor_/13758028

الاتاحة: https://doi.org/10.1371/journal.pone.0243871.s014