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1Academic Journal
المؤلفون: Yuhong Chen, Guy Hughes, Xueli Chen, Shaohong Qian, Wenjun Cao, Li Wang, Min Wang, Xinghuai Sun
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1061.8361; http://iovs.arvojournals.org/pdfaccess.ashx?url%3D/data/journals/iovs/933739/i1552-5783-56-4-2595.pdf
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2Academic Journal
المؤلفون: Yuhong Chen, Xueli Chen, Li Wang, Guy Hughes, Shaohong Qian, Xinghuai Sun
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1086.9565; http://iovs.arvojournals.org/pdfaccess.ashx?url%3D/data/journals/iovs/932990/i1552-5783-55-6-3797.pdf
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المؤلفون: Wei Ma, Jier Su, Hong Luo, Wang Yanling, Meng Zhaoyang, Junfa Li, Guy Hughes, Yi Yin, Song Han, Xiaolei Wang, Jingwen Ding
المصدر: Drug Design, Development and Therapy
مصطلحات موضوعية: Male, Retinal Ganglion Cells, retina, genetic structures, Ependymoglial Cells, Pharmaceutical Science, Apoptosis, Retinal ganglion, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, medicine, Animals, Gliosis, Ganglion cell layer, Original Research, Pharmacology, Müller cells, Retina, Drug Design, Development and Therapy, TUNEL assay, Glial fibrillary acidic protein, biology, business.industry, Tumor Necrosis Factor-alpha, Retinal, Molecular biology, Rats, Disease Models, Animal, medicine.anatomical_structure, glaucoma, α-aminoadipic acid, chemistry, Anesthesia, TNF-α, 030221 ophthalmology & optometry, biology.protein, Ocular Hypertension, sense organs, medicine.symptom, Cell activation, business, 2-Aminoadipic Acid, 030217 neurology & neurosurgery, acute ocular hypertension
وصف الملف: text/html
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المؤلفون: Alison Cohan, Mark White, Eric K. Brown, Guy Hughes
المصدر: Pacific Science. 68:19-31
مصطلحات موضوعية: geography, Multidisciplinary, geography.geographical_feature_category, Habitat, Feral animal, Ecology, Environmental science, Introduced species, Plant community, Vegetation, Understory, Lichen, Shrubland
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المؤلفون: Paul Mitchell, Lindsay A. Farrer, Ming Zhang, Mohammad Othman, Michiaki Kubo, André G. Uitterlinden, Anton Orlin, Kyu Hyung Park, Simon P. Harding, Yusuke Nakamura, Eric H Souied, William K. Scott, Gregory S. Hageman, Anita Agarwal, G. Rudolph, Henry Ferreyra, Yutaka Kiyohara, Humma Shahid, Yukinori Okada, Gregory Hannum, Hendrik P. N. Scholl, Christian Gieger, Clara Lee, H.-Erich Wichmann, Andrew R. Webster, Margaret A. Pericak-Vance, Brian L. Yaspan, Bernhard H. F. Weber, Gyungah Jun, Gabriëlle H.S. Buitendijk, Ching-Yu Cheng, Igor Kozak, Ana Maria Armbrecht, Gaetano R. Barile, Valentina Cipriani, Stephanie A. Hagstrom, Paul N. Baird, Margaret M. DeAngelis, Ronald Klein, Itay Chowers, Matthew Brooks, Mark J. Daly, Kimberly A Chin, Wei Chen, Thierry Léveillard, Cornelia M. van Duijn, Barbara E.K. Klein, Tien Yin Wong, Olivier Poch, Yi Yu, Peter Lichtner, Michael L. Klein, Lars G. Fritsche, Daniel E. Weeks, Radu Cojocaru, Gayle J.T. Pauer, Jaclyn L. Kovach, John R. Heckenlively, Jonathan L. Haines, Andrew J. Lotery, Nicholas Katsanis, Caroline C W Klaver, Stephan Ripke, Unnur Thorsteinsdottir, M. Carolina Ortube, Rando Allikmets, Nirubol Tosakulwong, Barbara Truitt, Robert P. Igo, Johanna M. Seddon, Kristine E. Lee, Emily Y. Chew, Kang Zhang, Debra A. Schaumberg, David Clayton, Frank G. Holz, Robyn Reynolds, Matthew Schu, Neal S. Peachey, Neel Gupta, Tatsuro Ishibashi, William Cade, Melinda Cain, Gwen M. Sturgill-Short, Jane C. Khan, Asbjorg Geirsdottir, Atsushi Takahashi, Thomas Meitinger, Belinda K. Cornes, Xueling Sim, Raymond Ripp, Evangelos Evangelou, Saddek Mohand-Said, Albert O. Edwards, Theru A. Sivakumaran, John P. A. Ioannidis, Kari Branham, Peronne Joseph, Jie Jin Wang, Chelsea E. Myers, Thomas W. Winkler, Johannes R. Vingerling, Robyn H. Guymer, Anthony T. Moore, Christos Haritoglou, Peter A. Campochiaro, Ronnie George, Chi-Chao Chan, Sudha K. Iyengar, Lucia Sobrin, Eranga N. Vithana, Haraldur Sigurdsson, James S. Friedman, Guy Hughes, Baljean Dhillon, Lingam Vijaya, Alan F. Wright, José-Alain Sahel, Rinki Ratna Priya, Tin Aung, R. Theodore Smith, Isabelle Audo, Satoshi Arakawa, Alexander J. Brucker, Gonçalo R. Abecasis, Evangelia E. Tsironi, Anand Swaroop, Mark Lathrop, Mustapha Benchaboune, Diana Zelenika, Joanna E. Merriam, Iris M. Heid, Denise J. Morgan, Michael B. Gorin, Donald J. Zack, Ling Zhao, Hreinn Stefansson, Andrea J. Richardson, Yvette P. Conley, Kari Stefansson, Giuliana Silvestri, Yoichiro Kamatani, Ivana K. Kim, Gudmar Thorleifsson, Stephen G. Schwartz, Alan C. Bird, Claudia N. Keilhauer, Euijung Ryu, Margaux A. Morrison, Chris Pappas, Dwight Stambolian, John R.W. Yates, Paul N. Bishop, Jesen Fagerness, Adam C. Naj, Peter J. Francis
المساهمون: Ophthalmology, Internal Medicine, Epidemiology, Obstetrics & Gynecology
المصدر: Nature genetics
Fritsche, L G, Chen, W, Schu, M, Yaspan, B L, Yu, Y, Thorleifsson, G, Zack, D J, Arakawa, S, Cipriani, V, Ripke, S, Igo, R P, Buitendijk, G H S, Sim, X, Weeks, D E, Guymer, R H, Merriam, J E, Francis, P J, Hannum, G, Agarwal, A, Armbrecht, A M, Audo, I, Aung, T, Barile, G R, Benchaboune, M, Bird, A C, Bishop, P N, Branham, K E, Brooks, M, Brucker, A J, Cade, W H, Cain, M S, Campochiaro, P A, Chan, C-C, Cheng, C-Y, Chew, E Y, Chin, K A, Chowers, I, Clayton, D G, Cojocaru, R, Conley, Y P, Cornes, B K, Daly, M J, Dhillon, B, Edwards, A O, Evangelou, E, Fagerness, J, Ferreyra, H A, Friedman, J S & Geirsdottir, A & Wright, A F 2013, ' Seven new loci associated with age-related macular degeneration ', Nature Genetics, vol. 45, no. 4, pp. 433-439 . https://doi.org/10.1038/ng.2578
Nature Genetics, 45(4), 433-439. Nature Publishing Groupمصطلحات موضوعية: Male, Genome-wide association study, Biology, Bioinformatics, Polymorphism, Single Nucleotide, Article, Macular Degeneration, 03 medical and health sciences, 0302 clinical medicine, Meta-Analysis as Topic, Risk Factors, Polymorphism (computer science), Genotype, Genetics, medicine, Humans, SNP, Genetic Predisposition to Disease, 030304 developmental biology, 0303 health sciences, Haplotype, Case-control study, Macular degeneration, medicine.disease, eye diseases, 3. Good health, Genetic Loci, Case-Control Studies, Factor H, 030221 ophthalmology & optometry, Female, Biomarkers, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Jiexi Zeng, Jing Luo, X Zhang, Weldon W Haw, Guy Hughes, L Tang, Ling Zhao, Xinran Wei, Kang Zhang, Peter X. Shaw, Clara Lee, Henry Ferreyra, Yaou Duan, Seanna Grob, Janet Lee, Jin Zhu, Michael H. Goldbaum, J Quach, Martin Krupa, Yuhong Chen
المصدر: Eye (London, England), vol 27, iss 2
مصطلحات موضوعية: Male, advanced age-related macular degeneration, Oncology, Aging, Pathology, genetic structures, Neurodegenerative, LIPC, Ophthalmology & Optometry, Cohort Studies, Macular Degeneration, Gene Frequency, Laboratory Study, 80 and over, 2.1 Biological and endogenous factors, Medicine, Aetiology, Promoter Regions, Genetic, Aged, 80 and over, biology, Single Nucleotide, Middle Aged, hepatic lipase, Female, Cohort study, medicine.medical_specialty, Clinical Sciences, Immunology, Polymorphism, Single Nucleotide, Promoter Regions, Genetic, Clinical Research, Opthalmology and Optometry, Age related, Internal medicine, Genetics, Humans, Genetic Predisposition to Disease, Polymorphism, Lipase, Allele, Eye Disease and Disorders of Vision, Allele frequency, Alleles, Aged, business.industry, Macular degeneration, medicine.disease, eye diseases, Ophthalmology, biology.protein, sense organs, Hepatic lipase, business
وصف الملف: application/pdf
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المؤلفون: Guy Hughes, Janet Lee, Xinrong Zhou, Henry Ferreyra, Kang Zhang, Jing Luo, Hongjun Du, William R. Freeman, Clara Lee, Igor Kozak, Seanna Grob
المصدر: Eye (London, England), vol 26, iss 8
مصطلحات موضوعية: Male, Aging, Visual acuity, genetic structures, Visual Acuity, Neurodegenerative, Eye, Ophthalmology & Optometry, Macular Degeneration, Gene Frequency, Genotype, 80 and over, Medicine, Fluorescein Angiography, Tomography, Aged, 80 and over, Serine Endopeptidases, Single Nucleotide, Complement C3, High-Temperature Requirement A Serine Peptidase 1, Complement C2, Choroidal neovascularization, Complement Factor H, Factor H, Disease Progression, Female, medicine.symptom, Tomography, Optical Coherence, Biotechnology, medicine.medical_specialty, Clinical Sciences, Immunology, Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, choroidal neovascularization, Clinical Research, Opthalmology and Optometry, Geographic Atrophy, Ophthalmology, Genetics, Humans, SNP, Polymorphism, Allele, Eye Disease and Disorders of Vision, age-related macular degeneration, Aged, business.industry, Macular degeneration, medicine.disease, Choroidal Neovascularization, eye diseases, Optical Coherence, Clinical Study, sense organs, business
وصف الملف: application/pdf
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المؤلفون: Hongjun Du, J Lee, Ling Zhao, K Schaf, Guy Hughes, Kang Zhang, Xinran Wei, Peter X. Shaw, David B. Granet, Mahmoud F El-Sahn, Jing Luo, Yaou Duan, J Quach, Seanna Grob
المصدر: Eye. 26:1039-1043
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Visual acuity, Eye Movements, Myotonia Congenita, genetic structures, Molecular Sequence Data, Visual Acuity, Audiology, Polymerase Chain Reaction, Sodium Channels, Chloride Channels, Ophthalmology, medicine, Humans, Eyelid Diseases, NAV1.4 Voltage-Gated Sodium Channel, Strabismus, Gene, Aged, Aged, 80 and over, CLCN1, Esotropia, Base Sequence, biology, Myotonia congenita, business.industry, medicine.disease, eye diseases, Pedigree, Child, Preschool, Mutation, Mutation (genetic algorithm), Clinical Study, biology.protein, Female, sense organs, medicine.symptom, business
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المؤلفون: L Zhao, Seanna Grob, Jin Zhu, J Lee, J Quach, Martin Krupa, R Corey, Jing Luo, Kang Zhang, Peter X. Shaw, Guy Hughes, Clara Lee, Igor Kozak, Hongjun Du
المصدر: Eye. 26:866-871
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Visual acuity, genetic structures, Visual Acuity, Genes, Recessive, Vitelliform macular dystrophy, Audiology, Compound heterozygosity, Ophthalmoscopy, chemistry.chemical_compound, Exon, Chloride Channels, Laboratory Study, Ophthalmology, Humans, Medicine, Bestrophins, Child, Eye Proteins, DNA Primers, medicine.diagnostic_test, business.industry, Retinal, Exons, medicine.disease, eye diseases, Pedigree, Vitelliform Macular Dystrophy, Serous fluid, chemistry, Child, Preschool, Mutation, Mutation (genetic algorithm), Female, medicine.symptom, business
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المؤلفون: Mark F. Rosenberg, John R. Riordan, Liam O'Ryan, Guy Hughes, Luba A. Aleksandrov, Zhefeng Zhao, Robert C. Ford
المصدر: Journal of Biological Chemistry. 286:42647-42654
مصطلحات موضوعية: 0303 health sciences, biology, Chemistry, 030302 biochemistry & molecular biology, Cell Biology, Biochemistry, Transmembrane protein, Cystic fibrosis transmembrane conductance regulator, 3. Good health, Cell biology, Transport protein, Cell membrane, 03 medical and health sciences, Transmembrane domain, medicine.anatomical_structure, Protein structure, Membrane protein, medicine, biology.protein, Molecular Biology, Ion channel, 030304 developmental biology
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المؤلفون: Mark H. Nelson, Dirk-Uwe Bartsch, Zhidan Tu, Igor Kozak, Li Zhang, Yaou Duan, Feng Lin, Siok Lam Lim, Hong Ouyang, Ling Zhao, Clara Lee, Janet Lee, Xinran Wei, Hong Feng, Hongjun Du, Matthew Bedell, Liangfang Zhang, Fang Lu, Hui Sun, Martin Krupa, Zhiguang Su, Henry Ferreyra, Peter X. Shaw, Zishan Feng, Seanna Grob, Kang Zhang, Zhenglin Yang, Jing Luo, Guy Hughes, Ming Zhang, Jin Zhu
المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 109, iss 34
مصطلحات موضوعية: Male, medicine.medical_specialty, Aging, genetic structures, Genotype, Inflammation, Drusen, Biology, Neurodegenerative, medicine.disease_cause, Inbred C57BL, Cardiovascular, Eye, Neovascularization, Mice, Macular Degeneration, Internal medicine, medicine, 80 and over, Genetics, Animals, Humans, 2.1 Biological and endogenous factors, Aetiology, Eye Disease and Disorders of Vision, Phospholipids, Aged, Aged, 80 and over, Multidisciplinary, Retinal pigment epithelium, Optic Disk Drusen, Angiography, Biological Sciences, Macular degeneration, medicine.disease, eye diseases, Complement system, Mice, Inbred C57BL, Oxygen, Endocrinology, medicine.anatomical_structure, Factor H, Complement Factor H, Immunology, sense organs, medicine.symptom, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Zhiguang Su, Yuan Hao Hsu, Xiaolei Wang, Vanda S. Lopes, Kang Zhang, Hongjun Du, Edward A. Dennis, Woong Sun, David S. Williams, Richard Harkewicz, Ming Zhang, Robert S. Molday, Guy Hughes, Hisham Alkuraya, Julian Esteve-Rudd, Matthew Bedell, Zongzhong Tong
المصدر: The Journal of biological chemistry, vol 287, iss 14
مصطلحات موضوعية: genetic structures, Neurodegenerative, Eye, Biochemistry, Medical and Health Sciences, chemistry.chemical_compound, Mice, Gene Knockout Techniques, Macular Degeneration, Retinal Rod Photoreceptor Cells, Lipid droplet, chemistry.chemical_classification, Unsaturated, Fatty Acids, food and beverages, Molecular Bases of Disease, Biological Sciences, Fatty acid synthase, medicine.anatomical_structure, Fatty Acids, Unsaturated, Retinal Cone Photoreceptor Cells, lipids (amino acids, peptides, and proteins), Polyunsaturated fatty acid, Biochemistry & Molecular Biology, Phosphorylcholine, Very long chain fatty acid, Electrophysiological Processes, Glycerophospholipids, Biology, Rare Diseases, medicine, Genetics, Animals, Eye Proteins, Molecular Biology, Eye Disease and Disorders of Vision, Retina, Cell Membrane, Neurosciences, Fatty acid, Membrane Proteins, Retinal, Cell Biology, eye diseases, Electrophysiological Phenomena, chemistry, Chemical Sciences, biology.protein, sense organs
وصف الملف: application/pdf
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المؤلفون: Zhenglin Yang, Xinran Wei, Brian C. Gilger, Jeffrey R. Sommer, Peter X. Shaw, Robert M. Petters, Jose L. Estrada, Bashir Mir, Curtis A Alexander, Jorge A. Piedrahita, Matthew Bedell, Seanna Grob, Kang Zhang, E. B. Collins, Guy Hughes
المصدر: The British journal of ophthalmology. 95(12)
مصطلحات موضوعية: Retinal degeneration, Pathology, medicine.medical_specialty, genetic structures, Swine, Transgene, Biology, medicine.disease_cause, Retina, Animals, Genetically Modified, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Macular Degeneration, medicine, Electroretinography, Animals, Eye Proteins, Mutation, medicine.diagnostic_test, Membrane Proteins, Retinal, Macular dystrophy, Macular degeneration, medicine.disease, Immunohistochemistry, eye diseases, Sensory Systems, Cell biology, Ophthalmology, Disease Models, Animal, medicine.anatomical_structure, chemistry, Microscopy, Fluorescence, sense organs, Gene Deletion
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المؤلفون: Chao Zhao, Jessica Chin, Yuhong Chen, Jiexi Zeng, Kang Zhang, Matthew Weed, Paul S. Bernstein, Daniel Kasuga, Michael H. Goldbaum, Matthew Bedell, Elizabeth Trood, Kevin Wang, William R. Freeman, Maureen Crocker, Francesca Salasar, Guy Hughes, Henry Ferreyra, Jeanette Buehler, Clara Lee, Igor Kozak, Zhenglin Yang, Victoria Fu
مصطلحات موضوعية: Oncology, Genetic Markers, Male, medicine.medical_specialty, Pathology, Genotype, Logistic regression, Polymorphism, Single Nucleotide, Article, Body Mass Index, Macular Degeneration, Atrophy, Internal medicine, Geographic Atrophy, medicine, Odds Ratio, Humans, Clinical significance, Genetic Predisposition to Disease, Aged, Aged, 80 and over, Models, Genetic, business.industry, Serine Endopeptidases, Smoking, Proteins, Odds ratio, Complement C3, High-Temperature Requirement A Serine Peptidase 1, Macular degeneration, Middle Aged, medicine.disease, eye diseases, Confidence interval, Choroidal Neovascularization, Ophthalmology, Choroidal neovascularization, Logistic Models, Phenotype, Complement Factor H, Female, sense organs, Metagenomics, medicine.symptom, business, Body mass index
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المؤلفون: Robert R. H. Anholt, Norman A. Zabriskie, Yuhong Chen, Guy Hughes, Robert N. Weinreb, Kang Zhang, Mary Anna Carbone
المساهمون: Toland, Amanda Ewart
المصدر: PloS one, vol 6, iss 5
PLoS ONE, Vol 6, Iss 5, p e20649 (2011)
Carbone, MA; Chen, Y; Hughes, GA; Weinreb, RN; Zabriskie, NA; Zhang, K; et al.(2011). Genes of the unfolded protein response pathway harbor risk alleles for primary open angle glaucoma. PLoS ONE, 6(5). doi: 10.1371/journal.pone.0020649. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/0671r17z
PLoS ONEمصطلحات موضوعية: Male, Linkage disequilibrium, Aging, genetic structures, lcsh:Medicine, Genome-wide association study, Neurodegenerative, Bioinformatics, Linkage Disequilibrium, Inhibitor of Apoptosis Proteins, 0302 clinical medicine, Genotype, Pathology, 2.1 Biological and endogenous factors, Aetiology, lcsh:Science, Genetics, 0303 health sciences, Multidisciplinary, Genomics, Single Nucleotide, 3. Good health, Open-Angle, Medicine, Female, Glaucoma, Open-Angle, Research Article, Signal Transduction, Open angle glaucoma, General Science & Technology, Protein Disulfide-Isomerases, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Model Organisms, Diagnostic Medicine, Clinical Research, Humans, Allele, Polymorphism, Eye Disease and Disorders of Vision, Genetic Association Studies, Myocilin, Alleles, 030304 developmental biology, Aged, Haplotype, Human Genome, lcsh:R, Neurosciences, Human Genetics, Glaucoma, Comparative Genomics, eye diseases, Ophthalmology, Haplotypes, Genetics of Disease, 030221 ophthalmology & optometry, Unfolded Protein Response, lcsh:Q, Biomarkers, General Pathology
وصف الملف: application/pdf
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المؤلفون: Xinghuai Sun, Shaohong Qian, Xueli Chen, Min Wang, Li Wang, Wenjun Cao, Guy Hughes, Yuhong Chen
المصدر: Investigative Opthalmology & Visual Science. 56:2595
مصطلحات موضوعية: Male, China, Intraocular pressure, medicine.medical_specialty, Genotype, genetic structures, Open angle glaucoma, Glaucoma, Single-nucleotide polymorphism, Gene Frequency, Risk Factors, Normal tension glaucoma, Ophthalmology, Prevalence, Humans, Medicine, Genetic Predisposition to Disease, Low Tension Glaucoma, Allele, Allele frequency, Intraocular Pressure, Polymorphism, Genetic, business.industry, Genetic Variation, DNA, Middle Aged, medicine.disease, eye diseases, Phenotype, Optometry, Female, sense organs, business, Glaucoma, Open-Angle
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المؤلفون: Xueli Chen, Guy Hughes, Xinghuai Sun, Li Wang, Yuhong Chen, Shaohong Qian
المصدر: Investigative Opthalmology & Visual Science. 55:3797
مصطلحات موضوعية: Male, China, medicine.medical_specialty, Genotype, Glaucoma, Single-nucleotide polymorphism, Subgroup analysis, Collagen Type XI, Pathogenesis, Gene Frequency, Ophthalmology, Internal medicine, PLEKHA7, Prevalence, medicine, Humans, SNP, Genetic Predisposition to Disease, Allele frequency, Genetic Association Studies, Polymorphism, Genetic, business.industry, DNA, Middle Aged, medicine.disease, Chinese people, Female, Carrier Proteins, Glaucoma, Angle-Closure, business, Follow-Up Studies
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