المؤلفون: Björn Papke, Sandip Murarka, Holger A Vogel, Pablo Martín-Gago, Marija Kovacevic, Dina C Truxius, Eyad K Fansa, Shehab Ismail, Gunther Zimmermann, Kaatje Heinelt, Carsten Schultz-Fademrecht, Alaa Al Saabi, Matthias Baumann, Peter Nussbaumer, Alfred Wittinghofer, Herbert Waldmann, Philippe I.H. Bastiaens

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/98e07183cd0647cabef2a5d6074729d8

المؤلفون: Philipp Johnen, Sophie Zimmermann, Michael Betz, Janneke Hendriks, Alexandra Zimmermann, Martina Marnet, Inessa De, Gunther Zimmermann, Christine Kibat, Irina Cornaciu, Vincent Mariaule, Andrea Pica, Damien Clavel, José Antonio Márquez, Matthias Witschel

المصدر: Pest management scienceREFERENCES. 78(8)

مصطلحات موضوعية: Herbicides, Insect Science, Weed Control, Oxazines, Plant Weeds, General Medicine, Thiolester Hydrolases, Agronomy and Crop Science, Herbicide Resistance, Hydrocarbons, Brominated

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f918487664303b3525acdf97a650f8
https://pubmed.ncbi.nlm.nih.gov/35604014

المؤلفون: Gunther Zimmermann, Björn Papke, Shehab Ismail, Nachiket Vartak, Anchal Chandra, Maike Hoffmann, Stephan A Hahn, Gemma Triola, Alfred Wittinghofer, Philippe I H Bastiaens, Herbert Waldmann

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://diyhpl.us/%7Ebryan/papers2/paperbot/8dd5231b5c2aae2a4a29fe1ff32b78ea.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1078.2765; http://diyhpl.us/%7Ebryan/papers2/paperbot/8dd5231b5c2aae2a4a29fe1ff32b78ea.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1078.2765
http://diyhpl.us/%7Ebryan/papers2/paperbot/8dd5231b5c2aae2a4a29fe1ff32b78ea.pdf

المؤلفون: Herbert Waldmann, Petra Janning, Slava Ziegler, Michael Winzker, Philipp Küchler, Gunther Zimmermann

المصدر: Bioorganic & Medicinal Chemistry. 26:1426-1434

مصطلحات موضوعية: 0301 basic medicine, Protein subunit, Clinical Biochemistry, Pharmaceutical Science, CDC42, GTPase, Biochemistry, Interactome, Protein–protein interaction, Structure-Activity Relationship, 03 medical and health sciences, Prenylation, Drug Discovery, Humans, Molecular Biology, Cells, Cultured, Cyclic Nucleotide Phosphodiesterases, Type 6, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Cell biology, 030104 developmental biology, Proteome, Molecular Medicine, Carrier Proteins, Lamin, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33c36dbd22fbd1ba577b3ed8dc90491
https://doi.org/10.1016/j.bmc.2017.08.033

المؤلفون: Philippe I. H. Bastiaens, Carsten Schultz-Fademrecht, Gunther Zimmermann, Peter Nussbaumer, Kaatje Heinelt, Marija Kovacevic, Pablo Martín-Gago, Sandip Murarka, Vogel H, Alaa Al Saabi, Eyad K. Fansa, Herbert Waldmann, Alfred Wittinghofer, Shehab Ismail, Björn Papke, Matthias Baumann, Dina C. Truxius

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Phosphodiesterase Inhibitors, Science, General Physics and Astronomy, Gene Expression, Antineoplastic Agents, Plasma protein binding, Biology, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Article, Protein Structure, Secondary, Proto-Oncogene Proteins p21(ras), Small Molecule Libraries, 03 medical and health sciences, Protein structure, Prenylation, Cell Line, Tumor, Humans, Protein Interaction Domains and Motifs, Binding site, Gene knockdown, Cyclic Nucleotide Phosphodiesterases, Type 6, Multidisciplinary, Binding Sites, Pancreatic Ducts, Epithelial Cells, General Chemistry, Recombinant Proteins, 3. Good health, Gene Expression Regulation, Neoplastic, Molecular Docking Simulation, 030104 developmental biology, Biochemistry, Cell culture, Pyrazines, Pyrazoles, Benzimidazoles, Signal transduction, Protein Binding, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ae3eb790413661219c2d78104c38f9
https://doaj.org/article/98e07183cd0647cabef2a5d6074729d8

المؤلفون: Gunther Zimmermann, Stefan Knapp, Davor Bajic, Sara Vanetti, Ulrike Rieder, Jörg Scheuermann, Dario Neri, Martin Mattarella, Apirat Chaikuad

المصدر: Chemistry-A European Journal
Chemistry-A European Journal, 23 (34)

مصطلحات موضوعية: 0301 basic medicine, Ligands, 01 natural sciences, Catalysis, Article, Chemical library, Small Molecule Libraries, 03 medical and health sciences, Residue (chemistry), chemistry.chemical_compound, Moiety, Mitogen-Activated Protein Kinase 8, Binding site, Gene Library, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Active site, General Chemistry, Combinatorial chemistry, 3. Good health, 0104 chemical sciences, 030104 developmental biology, Covalent bond, biology.protein, Linker, Cysteine

وصف الملف: application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea3d8140aaa8add5e929be92f0dab13
https://europepmc.org/articles/PMC5557334/

المؤلفون: Peter Nussbaumer, Philipp Küchler, Shehab Ismail, Herbert Waldmann, Alfred Wittinghofer, Gemma Triola, Sandip Murarka, Carsten Schultz-Fademrecht, Gunther Zimmermann

المصدر: Journal of Medicinal Chemistry. 57:5435-5448

مصطلحات موضوعية: Models, Molecular, Protein Prenylation, GTPase, Structure-Activity Relationship, Prenylation, Cell Line, Tumor, Drug Discovery, Atorvastatin, Humans, Computer Simulation, Pyrroles, Binding site, Cellular localization, Cyclic Nucleotide Phosphodiesterases, Type 6, Binding Sites, Chemistry, Drug discovery, Binding protein, Esters, Stereoisomerism, Small molecule, Kinetics, Biochemistry, Heptanoic Acids, Drug Design, ras Proteins, Thermodynamics, Molecular Medicine, Protein prenylation, Benzimidazoles, Ethers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7de396cb2b057ab590426c19890dcff
https://doi.org/10.1021/jm500632s

المؤلفون: Stephan A. Hahn, Gemma Triola, Philippe I. H. Bastiaens, Anchal Chandra, Maike Hoffmann, Herbert Waldmann, Nachiket Vartak, Shehab Ismail, Gunther Zimmermann, Björn Papke, Alfred Wittinghofer

المصدر: Nature. 497:638-642

مصطلحات موضوعية: Models, Molecular, MAP Kinase Signaling System, Molecular Conformation, Mice, Nude, Adenocarcinoma, Oncogene Protein p21(ras), Biology, medicine.disease_cause, Cell Line, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Binding site, neoplasms, Cell Proliferation, 030304 developmental biology, Cyclic Nucleotide Phosphodiesterases, Type 6, 0303 health sciences, Binding Sites, Multidisciplinary, Oncogene, Drug discovery, Hydrogen Bonding, Small molecule, Molecular biology, digestive system diseases, Cytoplasm, Cell culture, 030220 oncology & carcinogenesis, Cancer research, Benzimidazoles, KRAS, Mitogen-Activated Protein Kinases, Neoplasm Transplantation, Carcinoma, Pancreatic Ductal, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417eaf1b575631051e4b3fc77bed04e0
https://doi.org/10.1038/nature12205

المؤلفون: Gunther Zimmermann, Martin Mattarella, Dario Neri, Yizhou Li, Jörg Scheuermann, Ulrike Rieder

المصدر: ChemBioChem
ChemBioChem, 18 (9)

مصطلحات موضوعية: 0301 basic medicine, High-throughput screening, Oligonucleotides, Ligands, Biochemistry, DNA sequencing, Article, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Carbonic Anhydrase IX, Molecular Biology, Fluorescent Dyes, Microscale thermophoresis, Drug discovery, Oligonucleotide, Organic Chemistry, High-Throughput Nucleotide Sequencing, Nucleic Acid Hybridization, DNA, Sequence Analysis, DNA, Combinatorial chemistry, Dissociation constant, Acetazolamide, 030104 developmental biology, chemistry, DNA-encoded chemical libraries, Fluorescence anisotropy, Hit validation, koff, Molecular Medicine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3468905f6b6662cb633bd4743b3e3e8f

المؤلفون: Simone Möbitz, Katrin Weise, Herbert Waldmann, Gunther Zimmermann, Roland Winter, Gemma Triola, Shobhna Kapoor, Alexander Werkmüller

المصدر: Journal of the American Chemical Society. 134:11503-11510

مصطلحات موضوعية: Models, Molecular, Chemistry, Membrane lipids, Kinetics, Lipid microdomain, Phosphodiesterase, General Chemistry, Biochemistry, Catalysis, Cyclic Nucleotide Phosphodiesterases, Type 4, Membrane Lipids, Cytosol, Genes, ras, Colloid and Surface Chemistry, Membrane, Cytoplasm, Biophysics, Small GTPase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0b9aa870de8b7defc8980d98945aac
https://doi.org/10.1021/ja305518h

المؤلفون: Yizhou Li, Gunther Zimmermann, Jörg Scheuermann, Dario Neri

المصدر: ChemBioChem. 18:880-880

مصطلحات موضوعية: Real-time polymerase chain reaction, Computer science, DNA-encoded chemical library, High-throughput screening, Organic Chemistry, Molecular Medicine, Nanotechnology, Cover (algebra), Computational biology, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d9a46f0d8ad79c486c41f19b7dad8c8a
https://doi.org/10.1002/cbic.201700181

المؤلفون: Gunther Zimmermann, Jochen Spiegel, Herbert Waldmann, Tom N. Grossmann, Philipp M. Cromm

المساهمون: AIMMS

المصدر: Spiegel, J, Cromm, P M, Zimmermann, G, Grossmann, T N & Waldmann, H 2014, ' Small-molecule modulation of Ras signaling ', Nature Chemical Biology, vol. 10, no. 8, pp. 613-622 . https://doi.org/10.1038/nchembio.1560
Nature Chemical Biology, 10(8), 613-622. Nature Publishing Group

مصطلحات موضوعية: Gene isoform, biology, Protein Conformation, Molecular Sequence Data, Cell Biology, Small molecule, Guanosine Diphosphate, Small Molecule Libraries, Direct targeting, SDG 3 - Good Health and Well-being, Chaperone (protein), Anti-apoptotic Ras signalling cascade, Mutation, biology.protein, Cancer research, ras Proteins, Humans, Amino Acid Sequence, Guanosine Triphosphate, Molecular Targeted Therapy, Molecular Biology, Protein Kinases, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cd3fd10ed378605f7d32637998ffdf
https://research.vu.nl/en/publications/42c30a89-b14c-4600-b50d-a4bf8cbe3903

المؤلفون: Herbert Waldmann, Shobhna Kapoor, Gemma Triola, Katrin Weise, Roland Winter, Alexander Werkmüller, Gunther Zimmermann

المصدر: Biophysical Journal. 104(2)

مصطلحات موضوعية: Cytosol, Subcellular distribution, Membrane, Chemistry, technology, industry, and agriculture, Biophysics, Phosphodiesterase, Small GTPase, lipids (amino acids, peptides, and proteins), Delta subunit, Dissociation (chemistry), Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7ad22f7a373797a8c50796d9fee3d3

المؤلفون: Gemma Triola, Simone Möbitz, Gunther Zimmermann, Alexander Werkmüller, Roland Winter, Benjamin Sperlich, Herbert Waldmann, Shobhna Kapoor, Katrin Weise

المصدر: Biophysical Journal. 108:381a

مصطلحات موضوعية: 0303 health sciences, Calmodulin, biology, Chemistry, Biophysics, Raft, 010402 general chemistry, 01 natural sciences, Cell biology, 0104 chemical sciences, Subcellular distribution, 03 medical and health sciences, 0302 clinical medicine, Membrane, In vivo, biology.protein, Small GTPase, 030217 neurology & neurosurgery, Function (biology), Human cancer, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795c64c5433f7eed17ab29d46a96bf42
https://doi.org/10.1016/j.bpj.2014.11.2092

المؤلفون: Dario Neri, Yizhou Li, Gunther Zimmermann, Jörg Scheuermann

المصدر: ChemBioChem
ChemBioChem, 18 (9)

مصطلحات موضوعية: 0301 basic medicine, Computer science, High-throughput screening, Computational biology, 010402 general chemistry, Real-Time Polymerase Chain Reaction, 01 natural sciences, Biochemistry, DNA sequencing, Article, Chemical library, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, Peptide Library, Humans, Carbonic Anhydrase IX, Molecular Biology, Serum Albumin, DNA-encoded chemical library, Organic Chemistry, High-Throughput Nucleotide Sequencing, DNA, Sequence Analysis, DNA, Combinatorial chemistry, 0104 chemical sciences, 030104 developmental biology, Real-time polymerase chain reaction, chemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a8569b37d02261760b9740937177f8

المؤلفون: John F. Lalande, Gunther Zimmermann

المصدر: The Modern Language Journal. 70:298

مصطلحات موضوعية: Linguistics and Language, Political science, Language and Linguistics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::31d74ebfe9c0e7d15f2d015379173922
https://doi.org/10.2307/326952

المؤلفون: Alexander Werkmüller, Norbert Opitz, Christian Denter, Gunther Zimmermann, Herbert Waldmann, Roland Winter, Gemma Triola, Sebastian Koch

المصدر: ResearcherID

مصطلحات موضوعية: Membrane, Chemistry, Vesicle, Biophysics, Biological membrane, Fluorescence correlation spectroscopy, Raft, Ras superfamily, Fluorescence anisotropy, Rotational correlation time, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa92634ded7b1b66d92b6d4e16d63988

المؤلفون: BELLETTI, ADRIANA

المساهمون: Ed. by Grewendorf, Günther / Zimmermann, Thomas Ede, Belletti, Adriana

Relation: info:eu-repo/semantics/altIdentifier/isbn/9781614511601; info:eu-repo/semantics/altIdentifier/wos/WOS:000355691600012; ispartofbook:Discourse and Grammar. From Sentence Types to Lexical Categories; firstpage:91; lastpage:114; numberofpages:24; http://hdl.handle.net/11365/14122; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84989770553

الاتاحة: http://hdl.handle.net/11365/14122
https://doi.org/10.1515/9781614511601