المؤلفون: Anssi Nurminen, Serafiina Jaatinen, Sinja Taavitsainen, Gunilla Högnäs, Tom Lesluyes, Naser Ansari-Pour, Teemu Tolonen, Kerstin Haase, Antti Koskenalho, Matti Kankainen, Juho Jasu, Hanna Rauhala, Jenni Kesäniemi, Tiia Nikupaavola, Paula Kujala, Irina Rinta-Kiikka, Jarno Riikonen, Antti Kaipia, Teemu Murtola, Teuvo L. Tammela, Tapio Visakorpi, Matti Nykter, David C. Wedge, Peter Van Loo, G. Steven Bova

المصدر: Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: Prostate cancer, Cancer evolution, Cancer timing, Cancer anatomic origins, Spatiogenomic evolutionary tracing, Prostate cancer metastasis, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/7808b5d0d78d41449b9f048d30c6fc39

المؤلفون: Juho Jasu, Teemu Tolonen, Emmanuel S. Antonarakis, Himisha Beltran, Susan Halabi, Mario A. Eisenberger, Michael A. Carducci, Yohann Loriot, Kim Van der Eecken, Martijn Lolkema, Charles J. Ryan, Sinja Taavitsainen, Silke Gillessen, Gunilla Högnäs, Timo Talvitie, Robert J. Taylor, Antti Koskenalho, Piet Ost, Teemu J. Murtola, Irina Rinta-Kiikka, Teuvo Tammela, Anssi Auvinen, Paula Kujala, Thomas J. Smith, Pirkko-Liisa Kellokumpu-Lehtinen, William B. Isaacs, Matti Nykter, Juha Kesseli, G. Steven Bova

المصدر: European Urology Open Science, Vol 30, Iss , Pp 47-62 (2021)

مصطلحات موضوعية: Phenotyping, Prostate cancer, Metastasis, Autopsy, Electronic medical records, Complications, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666168321001075; https://doaj.org/toc/2666-1683

URL الوصول: https://doaj.org/article/11491b30f8294e5aade6fdfb5c1a7835

المؤلفون: Juho Jasu, Teemu Tolonen, Emmanuel S. Antonarakis, Himisha Beltran, Susan Halabi, Mario A. Eisenberger, Michael A. Carducci, Yohann Loriot, Kim Van der Eecken, M.P.J.K. (Martijn) Lolkema, Charles J. Ryan, Sinja Taavitsainen, Silke Gillessen, Gunilla Högnäs, Timo Talvitie, Robert J. Taylor, Antti Koskenalho, Piet Ost, Teemu J. Murtola, Irina Rinta-Kiikka, Teuvo Tammela, A Auvinen, Paula Kujala, Thomas J. Smith, Pirkko Liisa Kellokumpu-Lehtinen, William B. Isaacs, Matti Nykter, Juha Kesseli, G. Steven Bova

مصطلحات الفهرس: info:eu-repo/semantics/article

URL: http://repub.eur.nl/pub/136087

المؤلفون: Michael R. Emmert-Buck, Kevin J. Dawson, David E. Neal, Douglas F. Easton, Victoria Goody, Gunilla Högnäs, Kati Kivinummi, Rosalind A. Eeles, Gunes Gundem, Peter Van Loo, David C. Wedge, Peter J. Campbell, Barbara Kremeyer, Sarah O’Meara, Hayley C. Whitaker, Christopher S. Foster, Matti Annala, Tapio Visakorpi, Elli Papaemmanuil, Ludmil B. Alexandrov, G. Steven Bova, Daniel Brewer, Colin Cooper, Matti Nykter, Jose M. C. Tubio, William B. Isaacs, Ultan McDermott, Zsofia Kote-Jarai, Calli Latimer, Heini Kallio

المصدر: Nature

مصطلحات موضوعية: Male, Tumour heterogeneity, DNA Mutational Analysis, Context (language use), Biology, Malignancy, Article, Epigenesis, Genetic, Metastasis, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, medicine, Humans, Cell Lineage, Genes, Tumor Suppressor, Neoplasm Metastasis, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Prostatic Neoplasms, Cancer, medicine.disease, Clone Cells, 3. Good health, Receptors, Androgen, 030220 oncology & carcinogenesis, Cancer cell, Monoclonal, Immunology, Androgens, Disease Progression, Cancer research, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef7811805b4571f164e9edefcd21dd2
https://doi.org/10.1038/nature14347

المؤلفون: Jukka Laine, Johanna Ivaska, Astrid Murumägi, Gunilla Högnäs, Henrik Edgren, Saara Hämälistö, Kirsi Rilla, Olli Kallioniemi, Vesa Vilkki

المصدر: Högnäs, G, Hämälistö, S, Rilla, K, Laine, J O, Vilkki, V, Murumägi, A, Edgren, H, Kallioniemi, O & Ivaska, J 2013, ' Aneuploidy facilitates oncogenic transformation via specific genetic alterations, including Twist2 upregulation ', Carcinogenesis, vol. 34, no. 9, pp. 2000-2009 . https://doi.org/10.1093/carcin/bgt171

مصطلحات موضوعية: Integrins, Cancer Research, Cell signaling, Cell division, Cell Survival, Aneuploidy, Apoptosis, Biology, ta3111, Mice, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Downregulation and upregulation, microRNA, medicine, Animals, Humans, Neoplasm Invasiveness, 030304 developmental biology, Chromosome Aberrations, 0303 health sciences, Twist-Related Protein 1, ta1182, General Medicine, Fibroblasts, medicine.disease, Lipids, Phenotype, Molecular biology, Up-Regulation, Cell biology, Gene Expression Regulation, Neoplastic, Repressor Proteins, Gene expression profiling, MicroRNAs, 030220 oncology & carcinogenesis, Cytokinesis, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d709a7b7b0a16661f4dc4d15cfda17a3
https://doi.org/10.1093/carcin/bgt171

المؤلفون: Johanna Ivaska, Gunilla Högnäs, Kaisa Lehti, Karoliina Vuoriluoto, Pipsa Meller

المصدر: Vuoriluoto, K, Högnäs, G, Meller, P, Lehti, K & Ivaska, J 2011, ' Syndecan-1 and-4 differentially regulate oncogenic K-ras dependent cell invasion into collagen through α2β1 integrin and MT1-MMP ', Matrix Biology, vol. 30, no. 3, pp. 207-217 . https://doi.org/10.1016/j.matbio.2011.03.003

مصطلحات موضوعية: animal structures, Transcription, Genetic, Integrin, Cell Communication, Oncogene Protein p21(ras), CD49c, Cell Line, Collagen receptor, Extracellular matrix, 03 medical and health sciences, 0302 clinical medicine, Invasion, Cell Movement, MT1-MMP, Matrix Metalloproteinase 14, Humans, Neoplasm Invasiveness, K-ras, Cell adhesion, Molecular Biology, Glycosaminoglycans, 030304 developmental biology, 0303 health sciences, Contraction, biology, Chemistry, Extracellular Matrix, Cell biology, carbohydrates (lipids), Gene Expression Regulation, Integrin alpha M, 030220 oncology & carcinogenesis, embryonic structures, biology.protein, Syndecan-4, Integrin, beta 6, Syndecan, Collagen, Syndecan-1, Integrin alpha2beta1, Type I collagen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6282f193f1fe969be02c776587a9b50
https://doi.org/10.1016/j.matbio.2011.03.003

المؤلفون: William B. Isaacs, Sergei Häyrynen, Tommi Rantapero, Matti Nykter, Gunilla Högnäs, Tapio Visakorpi, Virpi Kivinen, Kati Kivinummi, Matti Annala, Teemu Tolonen, Heini Kallio, G. Steven Bova

المصدر: Cold Spring Harbor Molecular Case Studies

مصطلحات موضوعية: Research Report, 0303 health sciences, Mutation, malignant genitourinary tract tumor, General Medicine, Biology, medicine.disease, Bioinformatics, medicine.disease_cause, Primary tumor, neoplasm of the genitourinary tract, 3. Good health, Transcriptome, Androgen receptor, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, Cancer research, Missense mutation, Gene, PI3K/AKT/mTOR pathway, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac6eee046078fa1c0071288fa8edff2
http://europepmc.org/articles/PMC4853517

المؤلفون: Pegah Rouhi, Harri Sihto, Pekka Taimen, Jennifer P. Morton, Bryan W. Miller, Reetta Virtakoivu, Antti Arjonen, Riina Kaukonen, Gunilla Högnäs, Yihai Cao, Elmar Bucher, Owen J. Sansom, Johanna Ivaska, Heikki Joensuu, Elina Mattila

المصدر: Arjonen, A, Kaukonen, R, Mattila, E, Rouhi, P, Högnäs, G, Sihto, H, Miller, B W, Morton, J P, Bucher, E, Taimen, P, Virtakoivu, R, Cao, Y, Sansom, O J, Joensuu, H & Ivaska, J 2014, ' Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis ', Journal of Clinical Investigation, vol. 124, no. 3, pp. 1069-1082 . https://doi.org/10.1172/JCI67280

مصطلحات موضوعية: Integrins, Lung Neoplasms, Mutant, Mutation, Missense, Gene Expression, Mice, Nude, Breast Neoplasms, Kaplan-Meier Estimate, Myosins, Biology, medicine.disease_cause, Metastasis, Mice, Breast cancer, Downregulation and upregulation, SDG 3 - Good Health and Well-being, Cell Movement, Cell Line, Tumor, Cell Adhesion, medicine, Animals, Humans, Neoplasm Invasiveness, Pseudopodia, Cell adhesion, Cell Shape, Zebrafish, Mutation, ta1182, Cancer, General Medicine, medicine.disease, Up-Regulation, 3. Good health, Cell biology, Protein Transport, Cancer cell, Female, Tumor Suppressor Protein p53, Neoplasm Transplantation, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1940178b0d5c130f33693369ac3dc1
http://juuli.fi/Record/0252467114

المؤلفون: Elina Mattila, Henrik Edgren, Gunilla Högnäs, Olli Kallioniemi, Astrid Murumägi, Saara Tuomi, Stefan Veltel, Johanna Ivaska

المصدر: Oncogene
Högnäs, G, Tuomi, S, Veltel, S, Mattila, E, Murumägi, A, Edgren, H, Kallioniemi, O & Ivaska, J 2011, ' Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo ', Oncogene . https://doi.org/10.1038/onc.2011.527

مصطلحات موضوعية: Male, Integrins, Cancer Research, Cell, Integrin, Down-Regulation, Mice, Nude, Aneuploidy, cytokinesis, Biology, integrin traffic, Mice, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, SDG 3 - Good Health and Well-being, In vivo, Genetics, medicine, Animals, Humans, cancer, Breast, Molecular Biology, 030304 developmental biology, Ovarian Neoplasms, 0303 health sciences, Prostatic Neoplasms, Epithelial Cells, Cell migration, medicine.disease, In vitro, 3. Good health, Cell biology, Protein Transport, Cell Transformation, Neoplastic, medicine.anatomical_structure, rab GTP-Binding Proteins, 030220 oncology & carcinogenesis, biology.protein, Female, Original Article, Cytokinesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef6a3c322b069b3e17eb32100ae888d

المؤلفون: Gunes Gundem, David C. Wedge, Elli Papaemmanuil, Kevin J. Dawson, David E. Neal, Michael R. Emmert-Buck, Matti Annala, Hayley C. Whitaker, Calli Latimer, Victoria Goody, Sarah O’Meara, Douglas F. Easton, Ludmil B. Alexandrov, Rosalind A. Eeles, Gunilla Högnäs, Kati Kivinummi, Jose M. C. Tubio, Ultan McDermott, Barbara Kremeyer, Peter Van Loo, Christopher S. Foster, Matti Nykter, William B. Isaacs, Tapio Visakorpi, Zsofia Kote-Jarai, Peter J. Campbell, Colin Cooper, G. S. Bova, Daniel Brewer, Heini Kallio

المصدر: Cancer Research. 75:956-956

مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Cancer, Context (language use), Biology, medicine.disease, Malignancy, Metastasis, Androgen deprivation therapy, Androgen receptor, Prostate cancer, Oncology, Cancer cell, medicine, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::269647acecb6cdd6f76d570663a83145
https://doi.org/10.1158/1538-7445.am2015-956

المؤلفون: Gunes Gundem, Holger Heyn, Ultan McDermott, Matti Annala, Heini Kallio, Kati Kivinummi, David C. Wedge, Gunilla Högnäs, Tapio Visakorpi, William B. Isaacs, Peter Van Loo, G. Steven Bova, Michael R. Emmert-Buck, Matti Nykter, Manel Esteller

المصدر: Cancer Research. 75:3883-3883

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Prostatectomy, business.industry, medicine.medical_treatment, Disease, Bioinformatics, medicine.disease, Somatic evolution in cancer, Primary tumor, Radiation therapy, Transcriptome, Prostate cancer, Internal medicine, Gene duplication, medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::74c503cfb2b159a99bc52e49145abf9c
https://doi.org/10.1158/1538-7445.am2015-3883