المؤلفون: Souza, Fábio C. de, Brito, Larissa F., Silva, Marcos T., Sugimoto, Michelle A., Pinto, Ana Cristina S., Almeida, Patrícia D. O. de, Souza, Rodrigo O. S., Costa, Renyer A., Guilhon-Simplicio, Fernanda, Wanderley, Almir G., Oliveira, Kelson M. T. de, Sousa, Lirlândia P., Veiga-Junior, Valdir F. da, Lima, Emerson S.

المصدر: Journal of the Brazilian Chemical Society. July 2020 31(7)

مصطلحات موضوعية: 3-hydroxy-copalic acid, ibuprofen, Amazonia, copaiba, anti-inflammatory action

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000701335

المؤلفون: Verdam, Maria Christina S., Guilhon-Simplicio, Fernanda, Barbosa, Gleyce S., Magalhães, Alcineide L., Oliveira, Cinthya I.F.B., Almeida, Patrícia D.O., Machado, Tallita M., Vasconcellos, Marne C., Lima, Emerson S., Ohana, Débora T., Pereira, Maria M.

المصدر: Revista Brasileira de Farmacognosia. June 2015 25(3)

مصطلحات موضوعية: Justicia, Inflammation, Nitric oxide, COX-2

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000300264

المؤلفون: Verdam, Maria Christina S., Ohana, Débora T., Araújo, Maria Gracimar P., Guilhon-Simplicio, Fernanda, Mendonça, Maria Sílvia de, Pereira, Maria M.

المصدر: Revista Brasileira de Farmacognosia. December 2012 22(6)

مصطلحات موضوعية: cystoliths, diacytic stomata, glandular trachoma, non-glandular trichoma

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2012000600003

المؤلفون: Guilhon-Simplicio, Fernanda, Pereira, Maria de Meneses

المصدر: Química Nova. January 2011 34(6)

مصطلحات موضوعية: Malpighiaceae, Byrsonima, review

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000600021

المؤلفون: Carvalho, Maria José de, Pedrosa, Tatiana do Nascimento, Guilhon-Simplicio, Fernanda, Nunez, Cecília Verônica, Ohana, Débora Teixeira, Pereira, Maria de Meneses, Lima, Emerson Silva

المصدر: Acta Amazonica. March 2010 40(1)

مصطلحات موضوعية: Passiflora nitida, Coagulação sanguínea, Agregação plaquetária

وصف الملف: text/html

URL الوصول: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672010000100025

المؤلفون: Cruz, Daniel Luís Viana, Pinto, Ana Cristina da Silva, Matos, Leonardo Brandão, Silva, Junielson Soares da, Meireles, Sabrina da Fonseca, Gomes Júnior, Plínio Pereira, Chaves, Francisco Celio Maia, Guilhon-Simplicio, Fernanda, Rafael, Míriam Silva

المساهمون: Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico, Fundacao de Amparo a Pesquisa do Estado do Amazonas

المصدر: Toxicology Reports ; volume 13, page 101712 ; ISSN 2214-7500

الاتاحة: https://doi.org/10.1016/j.toxrep.2024.101712
https://api.elsevier.com/content/article/PII:S2214750024000957?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2214750024000957?httpAccept=text/plain

المؤلفون: Marques Machado, Tallita, Queiroz Valentim, Carolina, Domingo Rosales Acho, Leonard, Silva Lima, Emerson, Ferreira Koolen, Hector Henrique, Guilhon-Simplicio, Fernanda

المصدر: Revista Colombiana de Ciencias Químico-Farmacéuticas; Vol. 51 No. 3 (2022) ; Revista Colombiana de Ciencias Químico-Farmacéuticas; Vol. 51 Núm. 3 (2022) ; Revista Colombiana de Ciencias Químico-Farmacéuticas; v. 51 n. 3 (2022) ; 1909-6356 ; 0034-7418

مصطلحات موضوعية: antidiabético, estrés oxidativo, Byrsonima garcibarrigae, antidiabetic, oxidative stress

وصف الملف: application/pdf

Relation: https://revistas.unal.edu.co/index.php/rccquifa/article/view/96982/86803; https://revistas.unal.edu.co/index.php/rccquifa/article/view/96982

الاتاحة: https://revistas.unal.edu.co/index.php/rccquifa/article/view/96982

المؤلفون: Castro, Aryane Maia de, da Silva, Marcia de Jesus Amazonas, Lima, Emerson Silva, Guilhon-Simplício, Fernanda

مصطلحات موضوعية: P. acnes, Antiacne, Inflammation, Gel

Relation: https://doi.org/10.5281/zenodo.7114575; https://doi.org/10.5281/zenodo.7114576; oai:zenodo.org:7114576

الاتاحة: https://doi.org/10.5281/zenodo.7114576

المؤلفون: de Souza, Douglas Emanuel Mota, Bücker, Nádia Cristina Falcão, da Silva, Márcia de Jesus Amazonas, Lima, Silva Emerson, Guilhon-Simplício, Fernanda

مصطلحات موضوعية: Baldness, Alopecia, Apoptosis, Vascularization

Relation: https://doi.org/10.5281/zenodo.7114591; https://doi.org/10.5281/zenodo.7114592; oai:zenodo.org:7114592

الاتاحة: https://doi.org/10.5281/zenodo.7114592

المؤلفون: Martins, Henrique Gomes, Maia, Aryane Castro, Tashiro, Felipe Mota, Guilhon-Simplicio, Fernanda

مصطلحات موضوعية: Organic cosmetic, make up, Sunscreem, Propionibacterium acnes

Relation: https://doi.org/10.5281/zenodo.7114566; https://doi.org/10.5281/zenodo.7114567; oai:zenodo.org:7114567

الاتاحة: https://doi.org/10.5281/zenodo.7114567

المؤلفون: Gomes da Silva Ferreira, Rosilene, Guilhon-Simplicio, Fernanda, de Lima Yamaguchi, Klenicy Kazumy, Duarte de Lira, Priscila, Marques Machado, Tallita, Couto Ferreira, Márcio Antônio, da Veiga Júnior, Valdir Florêncio, Silva Lima, Emerson

المصدر: Revista Colombiana de Ciencias Químico-Farmacéuticas; Vol. 49 Núm. 2 (2020) ; Revista Colombiana de Ciencias Químico-Farmacéuticas; v. 49 n. 2 (2020) ; Revista Colombiana de Ciencias Químico-Farmacéuticas; Vol. 49 No. 2 (2020) ; 1909-6356 ; 0034-7418

مصطلحات موضوعية: Protium, amirinas alfa y beta, rendimientos de extracción, optimización de extracción, alpha and beta-amyrins, yielding extraction, extraction optimization

وصف الملف: application/pdf

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André, Pentacyclic triterpene bioavailability: an overview of in vitro and in vivo studies, Molecules, 22(3), 400 (2017).; A.L. Rüdiger, A.C. Siani, V.F. Veiga Júnior, The chemistry and pharmacology of the South America genus Protium Burm F (Burseraceae), Pharmacogn. Rev., 1(1), 93-104 (2007).; L. Hernández-Vázquez, S. Mangas, J. Palazón, A. Navarro-Ocaña, Valuable medicinal plants and resins: Commercial phytochemicals with bioactive properties, Ind. Crops Prod., 31(3), 476-480 (2010).; E. Biskup, M. Gołębiowski, R. Gniadecki, P. Stepnowski, E. Łojkowska, Triterpenoid α-amyrin stimulates proliferation of human keratinocytes but does not protect them against UVB damage, Acta Biochim. Pol., 59(2), 255-260 (2012).; R.C.P. Lima-Júnior, D.I.M. Sousa, G.A.C. Brito, C.M. Cunha, M.H. Chaves, V.S.N. Rao, F.A. Santos, Modulation of acute visceral nociception and bladder inflammation by plant triterpene, α,β-amyrin in a mouse model of cystitis: role of tachykinin NK1-receptors, and K+ATP channels, Inflamm. Res., 56, 487-494 (2007).; I. Matos, A.F. Bento, R. Marcon, R.F. Claudino, J.B. Calixto, Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: the relevance of cannabinoid system, Mol. Immunol., 54(3-4), 482-492 (2013).; R. Medeiros, M.F. Otuki, M.C.W. Avellar, J.B. Calixto, Mechanisms underlying the inhibitory actions of the pentacyclic triterpene α-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate, Eur. J. Pharmacol., 559(2-3), 227-235 (2007).; C.M. Melo, T.C. Morais, A.R. Tomé, G.A.C Brito, M.H. Chaves, V.S Rao, F.A. Santos, Anti-inflammatory effect of α,β-amyrin, a triterpene from Protium heptaphyllum, on cerulein-induced acute pancreatitis in mice, Inflamm. Res., 60(7), 673-681 (2011).; A.O. Nogueira, Y.I.S. Oliveira, B.L. Adjafre, M.E.A. Moraes, G.F. Aragão, Pharmacological effects of the isomeric mixture of alpha and beta amyrin from Protium heptaphyllum: a literature review, Fundam. Clin. Pharmacol., 33(1), 4-12 (2019).; K.K. Okoye, D.L. Ajaghaku, H.N. Okeke, E.E. Ilodigwe, C.S. Nworu, F.B.C. Okoye, Beta-amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity, Pharm. Biol., 52(11), 1478-1486 (2014).; M.F. Otuki, F. Vieira-Lima, Â. Malheiros, R.A. Yunes, J.B. Clixto, Topical antiinflammatory effects of the ether extract from Protium kleinii and α-amyrin pentacyclic triterpene, Eur. J. Pharmacol., 507(1-3), 253-259 (2005).; F.A. Santos, J.T. Frota, B.R. Arruda, T.S. de Melo, A.A.C.A da Silva, G.A.C. Brito, M.H. Chaves, V.S. Rao, Antihyperglycemic and hypolipidemic effects of α,β-amyrin, a triterpenoid mixture from Protium heptaphyllum in mice, Lipids Health Dis., 11, 98 (2012).; M. Shih, J. Cherng, Reduction of adhesion molecule production and alteration of eNOS and endothelin-1 mRNA expression in endothelium by Euphorbia hirta L. through its beneficial β-amyrin molecule, Molecules, 19(7), 10534-10545 (2014).; B. Gullón, P. Gullón, T.A. Lú-Chau, M.T. Moreira, J.M. Lema, G. Eibes, Optimization of solvent extraction of antioxidants from Eucalyptus globulus leaves by response surface methodology: characterization and assessment of their bioactive properties, Ind. Crops Prod., 108, 649-659 (2017).; S. Rodríguez-Rojo, A. Visentin, D. Maestri, M.J., Cocero, Assisted extraction of rosemary antioxidantes qith green solvents, J. Food Eng., 109(1), 98-103 (2012).; C.L. Roriz, L. Barros, M.A. Prieto, M.F. Barreiro, P. Morales, I.C.F.R. Ferreira, Modern extraction techniques optimized to extract betacyanins from Gomphrena globosa L., Ind. Crops Prod., 105, 29-40 (2017).; G.F. Aragão, M.C.C. Pinheiro, P.N. Bandeira, T.L.G Lemos, G.S.B. Viana, Analgesic and anti-inflammatory activities of the isomeric mixture of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March, J. Herb. Pharmacother., 7(2), 31-47 (2008).; P.N. Bandeira, T.L.G. Lemos, S.M.O. Costa, H.S. dos Santos, Obtenção de derivados da mistura triterpenoídica α- e β-amirina, Rev. Bras. Farmacogn., 17(2), 204-208 (2007).; S.J. Wagh, J.G. Gujar, V.G. Gaikar, Experimental and modeling studies on extraction of amyrins from latex of mandar (Calotropis gigantea), Indian J. Chem. Technol., 19, 427-433 (2012).; K.M.M.B. Carvalho, J.D.B. Marinho Filho, T.S. de Melo, A.J. Araújo, J.D.S. Quetz, M.D.P.S.S. da Cunha, K.M. de Melo, A.A.D.C.A. da Silva, A.R. Tomé, A. Havt, S.G.D.C. Fonseca, G.A.D.C. Brito, M.H. Chaves, V.S. Rao, F.A. Santos, The resin from Protium heptaphyllum prevents high-fat diet-induced obesity in mice: scientific evidence and potential mechanisms, J. Evid. Based Complementary Altern. Med., 2015, 106157 (2015).; G.M. Vieira Júnior, C.M.L. de Souza, M.H. Chaves, Resina de Protium heptaphyllum: isolamento, caracterização estrutural e avaliação das propriedades térmicas, Quim. Nova, 28(2), 183-187 (2005).; X. Guo, A.P. Bruins, T.R. Covey, Characterization of typical chemical background interferences in atmospheric pressure ionization liquid chromatography-mass spectrometry, Rapid. Commun. Mass Spectrom., 20(20), 3145-3150 (2006).; Y. Hayasaka, Analysis of phthalates in wine using liquid chromatography tandem mass spectrometry combined with a hold-back column: Chromatographic strategy to avoid the influence of pre-existing phthalate contamination in a liquid chromatography system, J. Chromatogr. A, 1372, 120-127 (2014).; H. Shen, L. Ying, Y. Cao, G. Pan, L. Zhou, Simultaneous determination of phthalates and parabens in cosmetic products by gas chromatography/mass spectrometry coupled with solid phase extraction (in Chinese), Se Pu, 25(2), 272-275 (2007).; M.O. Dias, L. Hamerski, A.C. Pinto, Separação semipreparativa de α e β-amirina por cromatografia líquida de alta eficiência, Quim. Nova, 34(4), 704-706 (2011).; F.W.A. Barros, P.N. Bandeira, D.J.B. Lima, A.S. Meira, S.S. de Farias, M.R.J.R. Albuquerque, H.S.D. Santos, T.L.G. Lemos, M.O. de Morais, L.V. Costa-Lotufo, C.D.O. Pessoa, Amyrin esters induce cell death by apoptosis in HL-60 leukemia cells, Bioorg. Med. Chem., 19(3), 1268-1276 (2011).; https://revistas.unal.edu.co/index.php/rccquifa/article/view/89923

الاتاحة: https://revistas.unal.edu.co/index.php/rccquifa/article/view/89923

المؤلفون: Guilhon-Simplicio, Fernanda, Rodrigues Serrao, Carlos Klinger, da Silva Pinto, Ana Cristina, Furtado Pacheco, Paulo Anastacio, Faria, Robson Xavier, Rocha, David Rodrigues, Ferreira, Vitor Francisco, Pereira-Junior, Raimundo Carlos, Matheeussen, An, Baán, Adrienn, Kiekens, Filip, de Pereira, Maria Meneses, Lima, Emerson Silva, De Winter, Hans, Cos, Paul

المصدر: 1747-0277 ; Chemical biology and drug design

مصطلحات موضوعية: Chemistry, Biology, Pharmacology. Therapy

Relation: info:eu-repo/semantics/altIdentifier/isi/000776162900001

الاتاحة: https://hdl.handle.net/10067/1879760151162165141

المؤلفون: Guilhon‐Simplicio, Fernanda, Serrão, Carlos Klinger Rodrigues, Pinto, Ana Cristina da Silva, Pacheco, Paulo Anastácio Furtado, Faria, Robson Xavier, da Rocha, David Rodrigues, Ferreira, Vitor Francisco, Pereira‐Junior, Raimundo Carlos, Matheeussen, An, Baán, Adrienn, Kiekens, Filip, de Meneses Pereira, Maria, Lima, Emerson Silva, Winter, Hans De, Cos, Paul

المساهمون: Fundação de Amparo à Pesquisa do Estado do Amazonas, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico

المصدر: Chemical Biology & Drug Design ; volume 99, issue 6, page 868-883 ; ISSN 1747-0277 1747-0285

الاتاحة: http://dx.doi.org/10.1111/cbdd.14040
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.14040
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/cbdd.14040

المؤلفون: Guilhon-Simplicio, Fernanda, Pinheiro, Carlos Cleomir de Souza, Conrado, Gabrielly Galdino, Barbosa, Gleyce dos Santos, Santos, Pierre Alexandre dos, Pereira, Maria de Meneses, Lima, Emerson Silva

مصطلحات موضوعية: Analgesic Agent, Antiinflammatory Agent, Antithrombocytic Agent, Antiulcer Agent, Beta Carotene, Byrsonima Japurensis Extract, Indometacin, Plant Extract, Superoxide, Unclassified Drug, Analgesic Activity, Animals Model, Anticoagulation, Antiinflammatory Activity, Antioxidant Activity, Antiulcer Activity, Bark, Bleaching, Blood Analysis, Clinical Evaluation, Concentration Response, Controlled Study, Dose Response, Drug Megadose, Drug Safety, Drug Screening, Female, Human, Human Tissue, Ic 50

وصف الملف: application/pdf

Relation: Volume 140, Número 2, Pags. 282-286; https://repositorio.inpa.gov.br/handle/1/16139

الاتاحة: https://repositorio.inpa.gov.br/handle/1/16139
https://doi.org/10.1016/j.jep.2012.01.018

المؤلفون: Carvalho, Maria José de, Pedrosa, Tatiana do Nascimento, Guilhon-Simplicio, Fernanda, Nunez, Cecilia Veronica, Ohana, Débora Teixeira, Pereira, Maria de Meneses, Lima, Emerson Silva

مصطلحات موضوعية: Passiflora Nitida, Blood Coagulation, Aggregation, Coagulação Sanguínea, Agregação Plaquetária

وصف الملف: application/pdf

Relation: Volume 40, Número 1, Pags. 199-206; https://repositorio.inpa.gov.br/handle/1/13495

الاتاحة: https://repositorio.inpa.gov.br/handle/1/13495
https://doi.org/10.1590/S0044-59672010000100025

المؤلفون: Carvalho, Maria Joséde, Pedrosa, Tatiana do Nascimento, Guilhon-Simplicio, Fernanda, Nunez, Cecília Verônica, Ohana, Débora Teixeira, Pereira, Maria de Meneses, Lima, Emerson Silva

المساهمون: BHL SciELO

مصطلحات موضوعية: Agregação plaquetária, Coagulação sanguínea, Passiflora nitida

Relation: https://www.biodiversitylibrary.org/part/165341

الاتاحة: https://www.biodiversitylibrary.org/part/165341

المؤلفون: Leandro, Fabrício Damasceno, Cabral, Layla Dutra Marinho, Machado, Tallita Marques, Koolen, Hector Henrique Ferreira, da Silva, Felipe Moura Araújo, Guilhon-Simplicio, Fernanda, da Silva, Marcelo Aparecido, Giusti-Paiva, Alexandre, Moura, Clarice de Carvalho Veloso, da Silva, Geraldo Alves

المصدر: Natural Product Research ; volume 35, issue 23, page 5549-5553 ; ISSN 1478-6419 1478-6427

الاتاحة: http://dx.doi.org/10.1080/14786419.2020.1795654
https://www.tandfonline.com/doi/pdf/10.1080/14786419.2020.1795654

المؤلفون: Fabrício Damasceno Leandro, Cabral, Layla Dutra Marinho, Tallita Marques Machado, Koolen, Hector Henrique Ferreira, Da Silva, Felipe Moura Araújo, Guilhon-Simplicio, Fernanda, Da Silva, Marcelo Aparecido, Giusti-Paiva, Alexandre, De Carvalho Veloso Moura, Clarice, Da Silva, Geraldo Alves

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::45628cc089a351f7616154451ee6c93e

المؤلفون: Leandro, Fabrício Damasceno, Cabral, Layla Dutra Marinho, Machado, Tallita Marques, Koolen, Hector Henrique Ferreira, da Silva, Felipe Moura Araújo, Guilhon-Simplicio, Fernanda, da Silva, Marcelo Aparecido, Giusti-Paiva, Alexandre, Moura, Clarice de Carvalho Veloso, da Silva, Geraldo Alves

المصدر: Natural Product Research; Dec 2021, Vol. 35 Issue 23, p5549-5553, 5p

مصطلحات موضوعية: PLANT disease treatment, STEROID saponins, GALLIC acid, EPIGALLOCATECHIN gallate, LIPOPOLYSACCHARIDES, COUMARINS, GINGER

المؤلفون: da Silva Ferreira, Rosilene Gomes¹, Guilhon-Simplicio, Fernanda², Rosales Acho, Leonard Domingo², Yared Batista, Nayana³, do Carmo Guedes-Junior, Frank², Leão Ferreira, Mayla Silva³, Marques Barcellos, José Fernando³, Florêncio Veiga-Junior, Valdir⁴, Silva Lima, Emerson² eslima@ufam.edu.br

المصدر: Avicenna Journal of Phytomedicine. Sep/Oct2021, Vol. 11 Issue 5, p451-463. 13p.

مصطلحات موضوعية: *HYPERGLYCEMIA, *TRITERPENES, *METABOLIC disorders, *OBESITY, *BODY weight, *LABORATORY mice