المؤلفون: Tse, Edwin G., Aithani, Laksh, Anderson, Mark, Cardoso-Silva, Jonathan, Cincilla, Giovanni, Conduit, Gareth J., Galushka, Mykola, Guan, Davy, Hallyburton, Irene, Irwin, Benedict W. J., Kirk, Kiaran, Lehane, Adele M., Lindblom, Julia C. R., Lui, Raymond, Matthews, Slade, McCulloch, James, Motion, Alice, Ng, Ho Leung, Öeren, Mario, Robertson, Murray N., Spadavecchio, Vito, Tatsis, Vasileios A., van Hoorn, Willem P., Wade, Alexander D., Whitehead, Thomas M., Willis, Paul, Todd, Matthew H.

مصطلحات موضوعية: Therapeutics. Pharmacology

وصف الملف: text

Relation: https://strathprints.strath.ac.uk/78704/1/Tse_etal_JMC_2021_experimental_validation_of_predictive_models_in_a_series_of_novel_antimalarials.pdf; Tse, Edwin G. and Aithani, Laksh and Anderson, Mark and Cardoso-Silva, Jonathan and Cincilla, Giovanni and Conduit, Gareth J. and Galushka, Mykola and Guan, Davy and Hallyburton, Irene and Irwin, Benedict W. J. and Kirk, Kiaran and Lehane, Adele M. and Lindblom, Julia C. R. and Lui, Raymond and Matthews, Slade and McCulloch, James and Motion, Alice and Ng, Ho Leung and Öeren, Mario and Robertson, Murray N. and Spadavecchio, Vito and Tatsis, Vasileios A. and van Hoorn, Willem P. and Wade, Alexander D. and Whitehead, Thomas M. and Willis, Paul and Todd, Matthew H. (2021 ) An open drug discovery competition : experimental validation of predictive models in a series of novel antimalarials. Journal of Medicinal Chemistry , 64 (22). pp. 16450-16463. ISSN 0022-2623

الاتاحة: https://strathprints.strath.ac.uk/78704/
https://strathprints.strath.ac.uk/78704/1/Tse_etal_JMC_2021_experimental_validation_of_predictive_models_in_a_series_of_novel_antimalarials.pdf
https://doi.org/10.1021/acs.jmedchem.1c00313

المؤلفون: Tse, Edwin G, Aithani, Laksh, Anderson, Mark, Cardoso-Silva, Jonathan, Cincilla, Giovanni, Conduit, Gareth J, Galushka, Mykola, Guan, Davy, Hallyburton, Irene, Irwin, Benedict WJ, Kirk, Kiaran, Lehane, Adele M, Lindblom, Julia CR, Lui, Raymond, Matthews, Slade, McCulloch, James, Motion, Alice, Ng, Ho Leung, Öeren, Mario, Robertson, Murray N, Spadavecchio, Vito, Tatsis, Vasileios A, van Hoorn, Willem P, Wade, Alexander D, Whitehead, Thomas M, Willis, Paul, Todd, Matthew H

مصطلحات موضوعية: Antimalarials, Calcium-Transporting ATPases, Drug Discovery, Enzyme Inhibitors, Humans, Models, Biological, Plasmodium falciparum, Structure-Activity Relationship

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/330691

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/330691
https://doi.org/10.17863/CAM.78136

المؤلفون: Feeney, Samuel V., Lui, Raymond, Guan, Davy, Matthews, Slade

المصدر: Chemical Research in Toxicology ; volume 36, issue 8, page 1227-1237 ; ISSN 0893-228X 1520-5010

الاتاحة: http://dx.doi.org/10.1021/acs.chemrestox.2c00372
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.2c00372

المؤلفون: Lui, Raymond, Guan, Davy, Matthews, Slade

المساهمون: Department of Health and Ageing, Australian Government, Sydney Medical School

المصدر: Chemical Research in Toxicology ; volume 36, issue 8, page 1248-1254 ; ISSN 0893-228X 1520-5010

الاتاحة: http://dx.doi.org/10.1021/acs.chemrestox.2c00385
https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.2c00385

المؤلفون: Guan, Davy, Fan, Kevin, Spence, Ian, Matthews, Slade

المصدر: Data in Brief ; volume 17, page 876-884 ; ISSN 2352-3409

الاتاحة: http://dx.doi.org/10.1016/j.dib.2018.01.077
https://api.elsevier.com/content/article/PII:S2352340918300805?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2352340918300805?httpAccept=text/plain

المؤلفون: Medina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes, Blaskovich, Mark A.T.

المساهمون: Wellcome Trust, National Health and Medical Research Council, University of Queensland, Consejo Nacional de Ciencia y Tecnología

المصدر: Drug Discovery Today ; volume 27, issue 5, page 1420-1430 ; ISSN 1359-6446

الاتاحة: http://dx.doi.org/10.1016/j.drudis.2022.02.021
https://api.elsevier.com/content/article/PII:S1359644622000794?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1359644622000794?httpAccept=text/plain

المؤلفون: Guan, Davy, Lui, Raymond, Matthews, Slade

المصدر: Journal of Computer-Aided Molecular Design ; volume 34, issue 5, page 511-522 ; ISSN 0920-654X 1573-4951

الاتاحة: http://dx.doi.org/10.1007/s10822-020-00278-1
http://link.springer.com/content/pdf/10.1007/s10822-020-00278-1.pdf
http://link.springer.com/article/10.1007/s10822-020-00278-1/fulltext.html

المؤلفون: Lui, Raymond, Guan, Davy, Matthews, Slade

المصدر: Journal of Computer-Aided Molecular Design ; volume 34, issue 5, page 523-534 ; ISSN 0920-654X 1573-4951

الاتاحة: http://dx.doi.org/10.1007/s10822-020-00279-0
http://link.springer.com/content/pdf/10.1007/s10822-020-00279-0.pdf
http://link.springer.com/article/10.1007/s10822-020-00279-0/fulltext.html

المؤلفون: Guan, Davy

مصطلحات موضوعية: modelling, computational, pharmacology, qsar, chemistry, toxicology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______293::6185134a95febd96e006b5fbdacf6daf
https://hdl.handle.net/2123/22914

المؤلفون: Tse, Edwin, Aithani, Laksh, Anderson, Mark, Cardoso-Silva, Jonathan, Cincilla, Giovanni, Conduit, Gareth J., Galushka, Mykola, Guan, Davy, Hallyburton, Irene, Irwin, Benedict W. J., Kirk, Kiaran, Lehane, Adele M., Lindblom, Julia, Lui, Raymond, Matthews, Slade, McCulloch, James, Motion, Alice, Ng, Ho Leung, Öeren, Mario, Robertson, Murray N., Spadavecchio, Vito, Tatsis, Vasileios, P. van Hoorn, Willem, Wade, Alexander, Whitehead, Thomas M., Willis, Paul, Todd, Matthew

الاتاحة: http://dx.doi.org/10.26434/chemrxiv.13194755.v1
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/60c751a59abda283a4f8dc53/original/an-open-drug-discovery-competition-experimental-validation-of-predictive-models-in-a-series-of-novel-antimalarials.pdf

المؤلفون: Guan, Davy, Fan, Kevin, Spence, Ian, Matthews, Slade

المساهمون: Sydney Medical School, The University of Sydney

المصدر: Regulatory Toxicology and Pharmacology ; volume 94, page 8-15 ; ISSN 0273-2300

الاتاحة: http://dx.doi.org/10.1016/j.yrtph.2018.01.008
https://api.elsevier.com/content/article/PII:S0273230018300084?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0273230018300084?httpAccept=text/plain

المؤلفون: Guan, Davy, Lui, Raymond, Matthews, Slade T.

المصدر: Current Research in Toxicology; January 2024, Vol. 7 Issue: 1

المؤلفون: Tse, Edwin G, Aithani, Laksh, Anderson, Mark, Cardoso-Silva, Jonathan, Cincilla, Giovanni, Conduit, Gareth J, Galushka, Mykola, Guan, Davy, Hallyburton, Irene, Irwin, Benedict WJ, Kirk, Kiaran, Lehane, Adele M, Lindblom, Julia CR, Lui, Raymond, Matthews, Slade, McCulloch, James, Motion, Alice, Ng, Ho Leung, Öeren, Mario, Robertson, Murray N, Spadavecchio, Vito, Tatsis, Vasileios A, Van Hoorn, Willem P, Wade, Alexander D, Whitehead, Thomas M, Willis, Paul, Todd, Matthew H

مصطلحات موضوعية: Antimalarials, Structure-Activity Relationship, Drug Discovery, Plasmodium falciparum, Humans, Calcium-Transporting ATPases, Enzyme Inhibitors, Models, Biological, 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::caf8306a40952608c9a25e5c9c95af82

المؤلفون: Davy Guan, Alexander Wade, Edwin G Tse, Alice Motion, Willem P. van Hoorn, Jonathan Cardoso-Silva, Adele M. Lehane, Giovanni Cincilla, Mario Öeren, Julia C. R. Lindblom, Mykola Galushka, Murray N. Robertson, Matthew H. Todd, James McCulloch, Slade Matthews, Mark G. Anderson, Benedict Irwin, Thomas M. Whitehead, Paul Willis, Laksh Aithani, Ho Leung Ng, Gareth Conduit, Vasileios A. Tatsis, Vito Spadavecchio, Raymond Lui, Kiaran Kirk, Irene Hallyburton

المساهمون: Tse, Edwin G [0000-0002-9133-9274], Cincilla, Giovanni [0000-0002-5242-0707], Guan, Davy [0000-0001-6290-3166], Lehane, Adele M [0000-0002-0050-9101], Matthews, Slade [0000-0002-1652-543X], Motion, Alice [0000-0002-5859-7888], Ng, Ho Leung [0000-0002-6415-1938], Robertson, Murray N [0000-0001-9543-7667], Wade, Alexander D [0000-0003-1500-3733], Todd, Matthew H [0000-0001-7096-4751], Apollo - University of Cambridge Repository

المصدر: Journal of medicinal chemistry. 64(22)

مصطلحات موضوعية: RM, Plasmodium falciparum, Calcium-Transporting ATPases, Public domain, 01 natural sciences, Models, Biological, Competition (economics), 03 medical and health sciences, Antimalarials, Structure-Activity Relationship, Drug Discovery, medicine, Humans, Enzyme Inhibitors, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Drug discovery, biology.organism_classification, Private sector, medicine.disease, Data science, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Identification (information), Molecular Medicine, Predictive modelling, Malaria

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226bb29c6cfb2827cc0b24dac6a0807c
https://pubmed.ncbi.nlm.nih.gov/34748707