المؤلفون: Perzolli, Alicia, Steinebach, Christian, Krönke, Jan, Gütschow, Michael, Zwaan, C. Michel, Barneh, Farnaz, Heidenreich, Olaf

المصدر: Cancers; Jan2025, Vol. 17 Issue 2, p211, 16p

مصطلحات موضوعية: RESEARCH funding, CELL proliferation, APOPTOSIS, TREATMENT effectiveness, GENE expression, RECOMBINANT proteins, CELL death, CELL survival

المؤلفون: Oneto, Angelo, Hamwi, Ghazl Al, Schäkel, Laura, Krüger, Nadine, Sylvester, Katharina, Petry, Marvin, Shamleh, Rasha Abu, Pillaiyar, Thanigaimalai, Claff, Tobias, Schiedel, Anke C., Sträter, Norbert, Gütschow, Michael, Müller, Christa E.

المصدر: Journal of Medicinal Chemistry; 9/12/2024, Vol. 67 Issue 17, p14986-15011, 26p

المؤلفون: Conseil régional of Franche-Comté, Pachón-Angona, I., Bernard, Paul J., Simakov, Alexey, Maj, Maciej, Jozwiak, Krzysztof, Novotna, Anna, Lemke, Carina, Gütschow, Michael, Martin, Helene, Oset-Gasque, María Jesús, Contelles, José-Marco, Ismaili, Lhassane

مصطلحات الفهرس: Calcium channel inhibitors, Proteases inhibitors, Antioxidant response element, ORAC, Alzheimer’s disease, artículo

URL: http://hdl.handle.net/10261/345213
https://doi.org/10.3390/pharmaceutics16010121
Publisher's version
https://doi.org/10.3390/pharmaceutics16010121
Sí

المؤلفون: Voget, Rabea, Breidenbach, Julian, Claff, Tobias, Hingst, Alexandra, Sylvester, Katharina, Steinebach, Christian, Vu, Lan Phuong, Weiße, Renato H., Bartz, Ulrike, Sträter, Norbert, Müller, Christa E., Gütschow, Michael

المصدر: Acta Pharmaceutica Sinica B; ISSN 2211-3835; Acta Pharmaceutica Sinica B 2024;14(5):2349-2357

مصطلحات الفهرس: ddc:615, article, doc-type:article, publishedVersion

URL: https://pub.h-brs.de/frontdoor/index/index/docId/8300
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apsb.2024.03.001
info:eu-repo/semantics/altIdentifier/pmid/38799620

المؤلفون: Mangoni, Arduino A., Guillou, Catherine, Vanden Eynde, Jean Jacques, Hulme, Christopher, Jampilek, Josef, Li, Wei, Prokai-Tatrai, Katalin, Rautio, Jarkko, Collina, Simona, Tuccinardi, Tiziano, Sousa, Maria Emilia, Sabatier, Jean-Marc, Galdiero, Stefania, Karaman, Rafik, Kokotos, George, Torri, Giangiacomo, Luque, F. Javier, Vasconcelos, M. Helena, Hadjipavlou-Litina, Dimitra, Siciliano, Carlo, Gutschow, Michael, Ragno, Rino, Gomes, Paula A. C., Agrofoglio, Luigi A., Munoz-Torrero, Diego

المصدر: Molecules

مصطلحات موضوعية: Drug Discovery / methods, Humans, Molecular Targeted Therapy

وصف الملف: application/pdf

Relation: https://doi.org/10.3390/molecules24010130; Mangoni, A. A., Guillou, C., Vanden Eynde, J. J., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Luque, F. J., Vasconcelos, M. H., Hadjipavlou-Litina, D., Siciliano, C., Muñoz-Torrero, D. (2018). Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes⁻4. Molecules (Basel, Switzerland), 24(1), 130. https://doi.org/10.3390/molecules24010130; https://hdl.handle.net/20.500.12503/31906; 24

الاتاحة: https://hdl.handle.net/20.500.12503/31906

المؤلفون: Gutschow, Michael, Eynde, Jean Jacques Vanden, Jampilek, Josef, Kang, CongBao, Mangoni, Arduino A., Fossa, Paola, Karaman, Rafik, Trabocchi, Andrea, Scott, Peter J. H., Reynisson, Johannes, Rapposelli, Simona, Galdiero, Stefania, Winum, Jean-Yves, Brullo, Chiara, Prokai-Tatrai, Katalin, Sharma, Arun K., Schapira, Matthieu, Azuma, Yasu-Taka, Cerchia, Laura, Spetea, Mariana, Torri, Giangiacomo, Collina, Simona, Geronikaki, Athina, Garcia-Sosa, Alfonso T., Vasconcelos, M. Helena, Sousa, Maria Emilia, Kosalec, Ivan, Tuccinardi, Tiziano, Duarte, Iola F., Salvador, Jorge A. R., Bertinaria, Massimo, Pellecchia, Maurizio, Amato, Jussara, Rastelli, Giulio, Gomes, Paula A. C., Guedes, Rita C., Sabatier, Jean-Marc, Estevez-Braun, Ana, Pagano, Bruno, Mangani, Stefano, Ragno, Rino, Kokotos, George, Brindisi, Margherita, Gonzalez, Florenci V., Borges, Fernanda, Miloso, Mariarosaria, Rautio, Jarkko, Munoz-Torrero, Diego

المصدر: Molecules

مصطلحات موضوعية: Animals, Chemistry, Pharmaceutical, Drug Discovery / methods, Humans, Molecular Targeted Therapy, Pharmaceutical Preparations, Structure-Activity Relationship

وصف الملف: application/pdf

Relation: https://doi.org/10.3390/molecules25132968; Gütschow, M., Eynde, J., Jampilek, J., Kang, C., Mangoni, A. A., Fossa, P., Karaman, R., Trabocchi, A., Scott, P., Reynisson, J., Rapposelli, S., Galdiero, S., Winum, J. Y., Brullo, C., Prokai-Tatrai, K., Sharma, A. K., Schapira, M., Azuma, Y. T., Cerchia, L., Spetea, M., Muñoz-Torrero, D. (2020). Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7. Molecules (Basel, Switzerland), 25(13), 2968. https://doi.org/10.3390/molecules25132968; https://hdl.handle.net/20.500.12503/31907; 25; 13

الاتاحة: https://hdl.handle.net/20.500.12503/31907

المؤلفون: Vanden Eynde, Jean Jacques, Mangoni, Arduino A., Rautio, Jarkko, Leprince, Jerome, Azuma, Yasu-Taka, Garcia-Sosa, Alfonso T., Hulme, Christopher, Jampilek, Josef, Karaman, Rafik, Li, Wei, Gomes, Paula A. C., Hadjipavlou-Litina, Dimitra, Capasso, Raffaele, Geronikaki, Athina, Cerchia, Laura, Sabatier, Jean-Marc, Ragno, Rino, Tuccinardi, Tiziano, Trabocchi, Andrea, Winum, Jean-Yves, Luque, F. Javier, Prokai-Tatrai, Katalin, Spetea, Mariana, Gutschow, Michael, Kosalec, Ivan, Guillou, Catherine, Vasconcelos, M. Helena, Kokotos, George, Rastelli, Giulio, de Sousa, Maria Emilia, Manera, Clementina, Gemma, Sandra, Mangani, Stefano, Siciliano, Carlo, Galdiero, Stefania, Liu, Hong, Scott, Peter J. H., de Los Rios, Cristobal, Agrofoglio, Luigi A., Collina, Simona, Guedes, Rita C., Munoz-Torrero, Diego

المصدر: Molecules

مصطلحات موضوعية: Chemistry, Pharmaceutical, Drug Discovery, Humans

وصف الملف: application/pdf

Relation: https://doi.org/10.3390/molecules25010119; Vanden Eynde, J. J., Mangoni, A. A., Rautio, J., Leprince, J., Azuma, Y. T., García-Sosa, A. T., Hulme, C., Jampilek, J., Karaman, R., Li, W., Gomes, P., Hadjipavlou-Litina, D., Capasso, R., Geronikaki, A., Cerchia, L., Sabatier, J. M., Ragno, R., Tuccinardi, T., Trabocchi, A., Winum, J. Y., Muñoz-Torrero, D. (2019). Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6. Molecules (Basel, Switzerland), 25(1), 119. https://doi.org/10.3390/molecules25010119; https://hdl.handle.net/20.500.12503/31908; 25

الاتاحة: https://hdl.handle.net/20.500.12503/31908

المؤلفون: Mangoni, Arduino A., Tuccinardi, Tiziano, Collina, Simona, Vanden Eynde, Jean Jacques, Munoz-Torrero, Diego, Karaman, Rafik, Siciliano, Carlo, de Sousa, Maria Emilia, Prokai-Tatrai, Katalin, Rautio, Jarkko, Guillou, Catherine, Gutschow, Michael, Galdiero, Stefania, Liu, Hong, Agrofoglio, Luigi A., Sabatier, Jean-Marc, Hulme, Christopher, Kokotos, George, You, Qidong, Gomes, Paula A. C.

المصدر: Molecules

وصف الملف: application/pdf

Relation: https://doi.org/10.3390/molecules23071596; Mangoni, A. A., Tuccinardi, T., Collina, S., Vanden Eynde, J. J., Muñoz-Torrero, D., Karaman, R., Siciliano, C., de Sousa, M. E., Prokai-Tatrai, K., Rautio, J., Guillou, C., Gütschow, M., Galdiero, S., Liu, H., Agrofoglio, L. A., Sabatier, J. M., Hulme, C., Kokotos, G., You, Q., & Gomes, P. (2018). Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3. Molecules (Basel, Switzerland), 23(7), 1596. https://doi.org/10.3390/molecules23071596; https://hdl.handle.net/20.500.12503/31910; 23

الاتاحة: https://hdl.handle.net/20.500.12503/31910

المؤلفون: Bricelj, Aleša, Dora Ng, Yuen Lam, Gobec, Martina, Kuchta, Robert, Hu, Wanyi, Javornik, Špela, Rožič, Miha, Gütschow, Michael, Zheng, Guangrong, Krönke, Jan, Steinebach, Christian, Sosič, Izidor

المصدر: Chemistry - A European Journal; 8/12/2024, Vol. 30 Issue 45, p1-8, 8p

مصطلحات موضوعية: BCL-2 proteins, ACUTE myeloid leukemia, CHRONIC leukemia, LYMPHOCYTIC leukemia, PROTEOLYSIS

المؤلفون: Breidenbach, Julian, Voget, Rabea, Si, Yaoyao, Hingst, Alexandra, Claff, Tobias, Sylvester, Katharina, Wolf, Valentina, Krasniqi, Vesa, Useini, Abibe, Sträter, Norbert, Ogura, Yukino, Kawaguchi, Atsushi, Müller, Christa E., Gütschow, Michael

المصدر: Journal of Medicinal Chemistry; 6/13/2024, Vol. 67 Issue 11, p8757-8790, 34p

المؤلفون: Barton, Blaire E., Collins, Matthew K., Chau, Cindy H., Choo-Wosoba, Hyoyoung, Venzon, David J., Steinebach, Christian, Garchitorena, Kathleen M., Shah, Bhruga, Sarin, Eric L., Gütschow, Michael, Figg, William D.

المصدر: Biomolecules (2218-273X); Jun2024, Vol. 14 Issue 6, p725, 14p

مصطلحات موضوعية: MULTIPLE myeloma, THALIDOMIDE, WESTERN immunoblotting, BIOLOGICAL assay, SAPHENOUS vein, CD38 antigen

المؤلفون: Yamauchi, Yuki, Konno, Sho, Omura, Noriko, Yoshioka, Narumi, Hingst, Alexandra, Gütschow, Michael, Müller, Christa E., Taguchi, Akihiro, Taniguchi, Atsuhiko, Kawaguchi, Atsushi, Hayashi, Yoshio

المصدر: ACS Chemical Biology; 5/17/2024, Vol. 19 Issue 5, p1028-1034, 7p

المؤلفون: Mangoni, Arduino A, Eynde, Jean Jacques Vanden, Jampilek, Josef, Hadjipavlou-Litina, Dimitra, Liu, Hong, Reynisson, Jóhannes, Sousa, Maria Emília, Gomes, Paula A C, Prokai-Tatrai, Katalin, Tuccinardi, Tiziano, Sabatier, Jean-Marc, Luque, F Javier, Rautio, Jarkko, Karaman, Rafik, Vasconcelos, M Helena, Gemma, Sandra, Galdiero, Stefania, Hulme, Christopher, Collina, Simona, Gütschow, Michael, Kokotos, George, Siciliano, Carlo, Capasso, Raffaele, Agrofoglio, Luigi A, Ragno, Rino, Muñoz-Torrero, Diego

المساهمون: Mangoni, Arduino A, Eynde, Jean Jacques Vanden, Jampilek, Josef, Hadjipavlou-Litina, Dimitra, Liu, Hong, Reynisson, Jóhanne, Sousa, Maria Emília, Gomes, Paula A C, Prokai-Tatrai, Katalin, Tuccinardi, Tiziano, Sabatier, Jean-Marc, Luque, F Javier, Rautio, Jarkko, Karaman, Rafik, Vasconcelos, M Helena, Gemma, Sandra, Galdiero, Stefania, Hulme, Christopher, Collina, Simona, Gütschow, Michael, Kokotos, George, Siciliano, Carlo, Capasso, Raffaele, Agrofoglio, Luigi A, Ragno, Rino, Muñoz-Torrero, Diego

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/31262039; info:eu-repo/semantics/altIdentifier/wos/WOS:000476700300069; volume:24; issue:13; firstpage:1; lastpage:14; numberofpages:14; journal:MOLECULES; http://hdl.handle.net/11365/1075177; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85068372771; https://www.mdpi.com/1420-3049/24/13/2415

الاتاحة: http://hdl.handle.net/11365/1075177
https://doi.org/10.3390/molecules24132415
https://www.mdpi.com/1420-3049/24/13/2415

المؤلفون: Mangoni, Arduino A, Tuccinardi, Tiziano, Collina, Simona, Vanden Eynde, Jean Jacques, Muñoz-Torrero, Diego, Karaman, Rafik, Siciliano, Carlo, de Sousa, Maria Emília, Prokai-Tatrai, Katalin, Rautio, Jarkko, Guillou, Catherine, Gütschow, Michael, Galdiero, Stefania, Liu, Hong, Agrofoglio, Luigi A, Sabatier, Jean-Marc, Hulme, Christopher, Kokotos, George, You, Qidong, Gomes, Paula A C

المساهمون: Mangoni, Arduino A, Tuccinardi, Tiziano, Collina, Simona, Vanden Eynde, Jean Jacque, Muñoz-Torrero, Diego, Karaman, Rafik, Siciliano, Carlo, de Sousa, Maria Emília, Prokai-Tatrai, Katalin, Rautio, Jarkko, Guillou, Catherine, Gütschow, Michael, Galdiero, Stefania, Liu, Hong, Agrofoglio, Luigi A, Sabatier, Jean-Marc, Hulme, Christopher, Kokotos, George, You, Qidong, Gomes, Paula A C

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/29966350; info:eu-repo/semantics/altIdentifier/wos/WOS:000445301800099; volume:23; issue:7; numberofpages:10; journal:MOLECULES; http://hdl.handle.net/11568/944127; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85049488375; https://www.mdpi.com/1420-3049/23/7/1596

الاتاحة: http://hdl.handle.net/11568/944127
https://doi.org/10.3390/molecules23071596
https://www.mdpi.com/1420-3049/23/7/1596

المؤلفون: Pachón-Angona, Irene, Bernard, Paul J., Simakov, Alexey, Maj, Maciej, Jozwiak, Krzysztof, Novotna, Anna, Lemke, Carina, Gütschow, Michael, Martin, Helene, Oset-Gasque, María-Jesús, Contelles, José-Marco, Ismaili, Lhassane

المصدر: Pharmaceutics; Jan2024, Vol. 16 Issue 1, p121, 14p

مصطلحات موضوعية: CALCIUM ions, CALCIUM channels, NUCLEAR factor E2 related factor, LIGANDS (Biochemistry), OXIDANT status, ANTIOXIDANTS

المؤلفون: Muñoz Torrero, Diego, Mangoni, Arduino A., Guillou, Catherine, Collina, Simona, Eynde, Jean Jacques Vanden, Rautio, Jarkko, Keseru, György M., Hulme, Christopher, Chibale, Kelly, Luque, F. Javier, Karaman, Rafik, Gütschow, Michael, Liu, Hong, RAGNO, Rino

المساهمون: Muñoz Torrero, Diego, Mangoni, Arduino A., Guillou, Catherine, Collina, Simona, Eynde, Jean Jacques Vanden, Rautio, Jarkko, Keseru, György M., Hulme, Christopher, Chibale, Kelly, Luque, F. Javier, Karaman, Rafik, Gütschow, Michael, Liu, Hong, Ragno, Rino

مصطلحات موضوعية: medicine (all), organic chemistry, staphylococcus-aureu, inhibition, discovery, disease, analog, design

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/28475136; info:eu-repo/semantics/altIdentifier/wos/WOS:000404522900066; volume:22; issue:5; numberofpages:7; journal:MOLECULES; http://hdl.handle.net/11573/978520; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85020211000; http://www.mdpi.com/1420-3049/22/5/743/pdf

الاتاحة: http://hdl.handle.net/11573/978520
https://doi.org/10.3390/molecules22050743
http://www.mdpi.com/1420-3049/22/5/743/pdf

المؤلفون: Phuong Vu, Lan, Diehl, Claudia, Casement, Ryan, Bond, Adam, Steinebach, Christian, Strasek, Nika, Bricelj, Alesa, Perdih, Andrej, Schnakenburg, Gregor, Sosic, Izidor, Ciulli, Alessio, Gutschow, Michael

المساهمون: European Research Council, Innovative Medicines Initiative, Wellcome Trust, Volkswagen Foundation

الاتاحة: http://dx.doi.org/10.26434/chemrxiv-2023-5gbb6-v2
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/64c8b9a7658ec5f7e58bc5e8/original/expanding-the-structural-diversity-at-the-phenylene-core-of-ligands-for-the-von-hippel-lindau-vhl-e3-ubiquitin-ligase-development-of-highly-potent-hypoxia-inducible-factor-1alpha-hif-1alpha-stabilizers.pdf

المؤلفون: Steinebach, Christian, Bricelj, Aleša, Murgai, Arunima, Sosič, Izidor, Bischof, Luca, Ng, Yuen Lam Dora, Heim, Christopher, Maiwald, Samuel, Proj, Matic, Voget, Rabea, Feller, Felix, Košmrlj, Janez, Sapozhnikova, Valeriia, Schmidt, Annika, Zuleeg, Maximilian Rudolf, Lemnitzer, Patricia, Mertins, Philipp, Hansen, Finn K., Gütschow, Michael, Krönke, Jan

المصدر: Journal of Medicinal Chemistry; 11/9/2023, Vol. 66 Issue 21, p14513-14543, 31p

المؤلفون: Vu, Lan Phuong, Diehl, Claudia J., Casement, Ryan, Bond, Adam G., Steinebach, Christian, Strašek, Nika, Bricelj, Aleša, Perdih, Andrej, Schnakenburg, Gregor, Sosič, Izidor, Ciulli, Alessio, Gütschow, Michael

المصدر: Journal of Medicinal Chemistry; 9/28/2023, Vol. 66 Issue 18, p12776-12811, 36p

المؤلفون: Hermes, Cornelia, Richarz, René, Wirtz, Daniel A., Patt, Julian, Hanke, Wiebke, Kehraus, Stefan, Voß, Jan Hendrik, Küppers, Jim, Ohbayashi, Tsubasa, Namasivayam, Vigneshwaran, Alenfelder, Judith, Inoue, Asuka, Mergaert, Peter, Gütschow, Michael, Müller, Christa E., Kostenis, Evi, König, Gabriele M., Crüsemann, Max

المساهمون: Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Intéractions Plantes-Bactéries (PBI), Département Microbiologie (Dpt Microbio), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications, 2021, 12 (1), pp.144. ⟨10.1038/s41467-020-20418-3⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.144. ⟨10.1038/s41467-020-20418-3⟩

مصطلحات موضوعية: Natural products, Molecular Structure, Chromobacterium, [SDV]Life Sciences [q-bio], Science, Esterases, Medicinal chemistry, Biosynthesis, Article, Hemiptera, Molecular Docking Simulation, Gene Knockout Techniques, HEK293 Cells, Bacterial Proteins, Depsipeptides, Animals, GTP-Binding Protein alpha Subunits, Gq-G11, Humans, Peptides, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c7e750be03e5389994cc81c63d86217b
https://doaj.org/article/2463819dc4b944af9d1f08c6cace66cc