المؤلفون: Ashcroft, Felicity, Bourboula, Asimina, Mahammad, Nur, Barbayianni, Efrosini, Feuerherm, Astrid, Nguyen, Thanh, Hayashi, Daiki, Kokotou, Maroula, Alevizopoulos, Konstantinos, Dennis, Edward, Kokotos, George, Johansen, Berit

المصدر: Nature Communications. 16(1)

مصطلحات موضوعية: Humans, Group IV Phospholipases A2, Cell Line, Tumor, Ketones, Reactive Oxygen Species, Thiazoles, Antineoplastic Agents, Cell Survival, Oxidative Stress, Neoplasms, Enzyme Inhibitors

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7854834r
https://escholarship.org/content/qt7854834r/qt7854834r.pdf

المؤلفون: Hudson, Craig J, Groh, Adam MR, Macciardi, Fabio, Hudson, Rhys C

المصدر: American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 189(1-2)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biological Sciences, Biomedical and Clinical Sciences, Genetics, Asian People, China, Group IV Phospholipases A2, Humans, Microsatellite Repeats, Polymorphism, Genetic, Schizophrenia, White People, Clinical Sciences, Neurosciences, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3ph1b30t

المؤلفون: Feuerherm, AJ, Dennis, EA, Johansen, B

المصدر: Arthritis Research & Therapy. 21(1)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Arthritis, Autoimmune Disease, Aetiology, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, Development of treatments and therapeutic interventions, Inflammatory and immune system, Animals, Antirheumatic Agents, Arachidonic Acid, Arthritis, Experimental, Cell Line, Tumor, Dinoprostone, Etanercept, Fatty Acids, Omega-3, Group IV Phospholipases A2, Humans, Male, Methotrexate, Mice, Inbred DBA, Molecular Structure, Synovial Membrane, cPLA2 alpha, Disease-modifying, Anti-rheumatic, Small molecule inhibitors, cPLA2α, Clinical Sciences, Immunology, Public Health and Health Services, Arthritis & Rheumatology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2r85z4nj

المؤلفون: Kokotou, Maroula G, Galiatsatou, Gerasimia, Magrioti, Victoria, Koutoulogenis, Giorgos, Barbayianni, Efrosini, Limnios, Dimitris, Mouchlis, Varnavas D, Satpathy, Banita, Navratil, Aaron, Dennis, Edward A, Kokotos, George

المصدر: Scientific reports. 7(1)

مصطلحات موضوعية: Macrophages, Animals, Mice, Esters, Anti-Inflammatory Agents, Inflammation Mediators, Enzyme Inhibitors, Group IV Phospholipases A2, Molecular Docking Simulation, RAW 264.7 Cells

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7ft8s6xx

المؤلفون: Antonopoulou, Georgia, Magrioti, Victoria, Kokotou, Maroula G, Nikolaou, Aikaterini, Barbayianni, Efrosini, Mouchlis, Varnavas D, Dennis, Edward A, Kokotos, George

المصدر: Bioorganic & Medicinal Chemistry. 24(19)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Cytosol, Drug Design, Enzyme Inhibitors, Group IV Phospholipases A2, Humans, Pyridines, Structure-Activity Relationship, GIVA cPLA(2), Inhibitors, Lipophilicity, 2-Oxoamides, Phospholipase A(2), Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Biochemistry and cell biology, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9p3726th

المؤلفون: Pombo, Mónica, Lamé, Michael W, Walker, Naomi J, Huynh, Danh H, Tablin, Fern

المصدر: Toxicology Letters. 235(1)

مصطلحات موضوعية: Agent Orange & Dioxin, Hematology, 2.1 Biological and endogenous factors, Aetiology, Cardiovascular, Basic Helix-Loop-Helix Transcription Factors, Blood Platelets, Dose-Response Relationship, Drug, Enzyme Activation, Group IV Phospholipases A2, Humans, Ligands, Omeprazole, Peptide Fragments, Phosphorylation, Platelet Activation, Platelet Aggregation, Polychlorinated Dibenzodioxins, Protein Kinase Inhibitors, Proton Pump Inhibitors, Puromycin, RNA, Messenger, Receptors, Aryl Hydrocarbon, Receptors, Thrombin, Signal Transduction, Time Factors, Up-Regulation, p38 Mitogen-Activated Protein Kinases, AhR non-genomic pathway, Platelet priming, p38MAPK, cPLA(2), Platelet signaling, Environmental Science and Management, Pharmacology and Pharmaceutical Sciences, Toxicology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5wj2s4ds

المؤلفون: Kokotos, George, Feuerherm, Astrid J, Barbayianni, Efrosini, Shah, Ishita, Sæther, Mari, Magrioti, Victoria, Nguyen, Thuy, Constantinou-Kokotou, Violetta, Dennis, Edward A, Johansen, Berit

المصدر: Journal of Medicinal Chemistry. 57(18)

مصطلحات موضوعية: Arthritis, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Inflammatory and immune system, Animals, Arachidonic Acid, Blood Proteins, Cell Line, Tumor, Collagen, Cytosol, Dinoprostone, Drug Design, Group IV Phospholipases A2, Humans, Ketones, Male, Mice, Oleic Acid, Synovial Membrane, Thiazoles, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/52129411

المؤلفون: Norris, Paul C, Gosselin, David, Reichart, Donna, Glass, Christopher K, Dennis, Edward A

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 111(35)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Inflammatory and immune system, Animals, Aspirin, Celecoxib, Cell Line, Transformed, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors, Eicosanoids, Group IV Phospholipases A2, Hydroxyeicosatetraenoic Acids, Inflammasomes, Interleukin-1, Lipidoses, Macrophages, Male, Mice, Mice, Inbred C57BL, Pyrazoles, Receptors, Purinergic P2X7, Signal Transduction, Sulfonamides, Toll-Like Receptor 4, lipidomics, enzyme coupling, membrane remodeling

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3q28v810
https://escholarship.org/content/qt3q28v810/qt3q28v810.pdf

المؤلفون: Keleshian, Vasken L, Kellom, Matthew, Kim, Hyung-Wook, Taha, Ameer Y, Cheon, Yewon, Igarashi, Miki, Rapoport, Stanley I, Rao, Jagadeesh S

المصدر: PloS one. 9(5)

مصطلحات موضوعية: Animals, Rats, Brain Diseases, Chronic Disease, Dietary Fats, Fatty Acids, Omega-3, Nerve Growth Factor, N-Methylaspartate, Excitatory Amino Acid Agonists, Brain Chemistry, Male, Lipid Metabolism, Interleukin-1beta, Group IV Phospholipases A2, Fatty Acids, Omega-3, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1453n6cg

المؤلفون: Hsu, Yuan-Hao, Dumlao, Darren S, Cao, Jian, Dennis, Edward A

المصدر: PloS one. 8(3)

مصطلحات موضوعية: Animals, Humans, Cardiolipins, Mass Spectrometry, Phospholipases A2, Phospholipases A2, Secretory, Phospholipases A2, Calcium-Independent, Group IV Phospholipases A2, Secretory, Calcium-Independent, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0j91q1r2

المؤلفون: Mouchlis, Varnavas D, Michopoulou, Vasiliki, Constantinou-Kokotou, Violetta, Mavromoustakos, Thomas, Dennis, Edward A, Kokotos, George

المصدر: Journal of Chemical Information and Modeling. 52(1)

مصطلحات موضوعية: 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Algorithms, Anti-Inflammatory Agents, Catalytic Domain, Drug Design, Drug Discovery, Enzyme Inhibitors, Group IV Phospholipases A2, Humans, Hydrophobic and Hydrophilic Interactions, Molecular Conformation, Molecular Dynamics Simulation, Pyridines, Structure-Activity Relationship, Substrate Specificity, Medicinal and Biomolecular Chemistry, Theoretical and Computational Chemistry, Computation Theory and Mathematics, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/25t3n3k9

المؤلفون: López‐Vales, Rubèn, Ghasemlou, Nader, Redensek, Adriana, Kerr, Bradley J, Barbayianni, Efrosini, Antonopoulou, Georgia, Baskakis, Constantinos, Rathore, Khizr I, Constantinou‐Kokotou, Violetta, Stephens, Daren, Shimizu, Takao, Dennis, Edward A, Kokotos, George, David, Samuel

المصدر: The FASEB Journal. 25(12)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Physical Injury - Accidents and Adverse Effects, Neurodegenerative, Spinal Cord Injury, Traumatic Head and Spine Injury, Neurological, Animals, Enzyme Inhibitors, Female, Group II Phospholipases A2, Group IV Phospholipases A2, Group VI Phospholipases A2, Locomotion, Mice, Mice, Inbred BALB C, Mice, Knockout, Phospholipase A2 Inhibitors, Phospholipases A2, Receptor Cross-Talk, Receptors, Prostaglandin E, EP1 Subtype, Spinal Cord Injuries, CNS injury, secondary damage, lipid metabolismw, prostaglandin receptors, Biochemistry and Cell Biology, Physiology, Medical Physiology, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2j21s97n

المؤلفون: Grkovich, Andrej, Armando, Aaron, Quehenberger, Oswald, Dennis, Edward A

المصدر: Biochimica et Biophysica Acta. 1791(10)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Adenosine Triphosphate, Animals, Arachidonic Acid, Diglycerides, Drug Synergism, Edetic Acid, Egtazic Acid, Enzyme Activation, Group IV Phospholipases A2, Lipopolysaccharides, Macrophages, Mice, Naphthalenes, Pancreatitis-Associated Proteins, Phosphatidate Phosphatase, Propranolol, Protein Kinase C, Pyrones, Time Factors, Toll-Like Receptor 4, Phosphatidic acid phosphohydrolase 1, Group IVA phospholipase-2, Lipopolysaccharide, Macrophage, Signal transduction, Inflammation, Arachidonic acid, Eicosanoid, Physical Sciences, Biological sciences, Physical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1452h15j

المؤلفون: Burke, John E, Babakhani, Arneh, Gorfe, Alemayehu A, Kokotos, George, Li, Sheng, Woods, Virgil L, McCammon, J Andrew, Dennis, Edward A

المصدر: Journal of the American Chemical Society. 131(23)

مصطلحات موضوعية: Analytical Chemistry, Chemical Sciences, Physical Chemistry, Amides, Anti-Inflammatory Agents, Non-Steroidal, Benzoates, Binding Sites, Caprylates, Deuterium, Deuterium Exchange Measurement, Drug Design, Enzyme Inhibitors, Group IV Phospholipases A2, Humans, Mass Spectrometry, Models, Molecular, Pyrrolidines, Sulfonamides, General Chemistry, Chemical sciences, Engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0vv8t0vn
https://escholarship.org/content/qt0vv8t0vn/qt0vv8t0vn.pdf

المؤلفون: Burke, John E, Dennis, Edward A

المصدر: Cardiovascular Drugs and Therapy. 23(1)

مصطلحات موضوعية: Animals, Elapid Venoms, Fatty Acids, Nonesterified, Group IA Phospholipases A2, Group IV Phospholipases A2, Group VI Phospholipases A2, Humans, Isoenzymes, Lysophospholipids, Phospholipases A2, Phospholipase A2, Lipid enzymology, Eicosanoids, PAF Hydrolase, Pharmacology and Pharmaceutical Sciences, Cardiovascular System & Hematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/161771q0

المؤلفون: Prévost, Nicolas, Mitsios, John V, Kato, Hisashi, Burke, John E, Dennis, Edward A, Shimizu, Takao, Shattil, Sanford J

المصدر: Blood. 113(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Medical Physiology, Biomedical and Clinical Sciences, Biological Sciences, Hematology, Clinical Research, Cardiovascular, Animals, Blood Platelets, CHO Cells, Cricetinae, Cricetulus, Enzyme Activation, Enzyme Inhibitors, Fibrinogen, Glycerophospholipids, Group IV Phospholipases A2, Humans, Mice, Mice, Knockout, Platelet Glycoprotein GPIIb-IIIa Complex, Protein Kinase C, Protein Kinase C beta, Pyrrolidines, Recombinant Proteins, Signal Transduction, Thromboxane A2, Vimentin, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Paediatrics and Reproductive Medicine, Immunology, Biochemistry and cell biology, Cardiovascular medicine and haematology, Paediatrics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/20g1s4vt
https://escholarship.org/content/qt20g1s4vt/qt20g1s4vt.pdf

المؤلفون: Grkovich, Andrej, Dennis, Edward A

المصدر: Advances in Biological Regulation. 49(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Animals, Cyclooxygenase 2, Diglycerides, Group IV Phospholipases A2, Inflammation, Phosphatidate Phosphatase, Signal Transduction, Toll-Like Receptor 4, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6pj5g9s1

المؤلفون: Prévost, Nicolas, Mitsios, John V, Kato, Hisashi, Burke, John E, Dennis, Edward A, Shimizu, Takao, Shattil, Sanford J

المصدر: Blood. 113(2)

مصطلحات موضوعية: Blood Platelets, CHO Cells, Animals, Mice, Knockout, Humans, Cricetulus, Mice, Pyrrolidines, Vimentin, Protein Kinase C, Thromboxane A2, Glycerophospholipids, Fibrinogen, Platelet Glycoprotein GPIIb-IIIa Complex, Recombinant Proteins, Enzyme Inhibitors, Signal Transduction, Enzyme Activation, Cricetinae, Group IV Phospholipases A2, Protein Kinase C beta, Knockout, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Paediatrics and Reproductive Medicine, Immunology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/20g1s4vt

المؤلفون: Burke, John E, Hsu, Yuan-Hao, Deems, Raymond A, Li, Sheng, Woods, Virgil L, Dennis, Edward A

المصدر: Journal of Biological Chemistry. 283(45)

مصطلحات موضوعية: Generic health relevance, Animals, Arachidonic Acids, Calcium, Catalytic Domain, Cell Membrane, Group IV Phospholipases A2, Humans, Organophosphonates, Phospholipid Ethers, Protein Binding, Protein Structure, Tertiary, Chemical Sciences, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9m82841k

المؤلفون: López-Vales, Rubèn, Navarro, Xavier, Shimizu, Takao, Baskakis, Constantinos, Kokotos, George, Constantinou-Kokotou, Violetta, Stephens, Daren, Dennis, Edward A, David, Samuel

المصدر: Brain. 131(Pt 10)

مصطلحات موضوعية: Neurodegenerative, Regenerative Medicine, Physical Injury - Accidents and Adverse Effects, Rare Diseases, Neurosciences, Underpinning research, 1.1 Normal biological development and functioning, Neurological, Animals, Axons, Fluorescent Antibody Technique, Fluorocarbons, Group IV Phospholipases A2, Group VI Phospholipases A2, Ketones, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, Microscopy, Electron, Models, Animal, Nerve Regeneration, Reverse Transcriptase Polymerase Chain Reaction, Sciatic Nerve, Skin, Wallerian Degeneration, axon regeneration, myelin, macrophage, phagocytosis, phospholipase A(2), sciatic nerve injury, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9pm5g4gd