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1
المؤلفون: Hutchins, George H., Kiehstaller, Sebastian, Poc, Pascal, Lewis, Abigail H., Oh, Jisun, Sadighi, Raya, Pearce, Nicholas, Ibrahim, Mohamed, Drienovska, Ivana, Rijs, Anouk M., Neubacher, Saskia, Hennig, Sven, Grossmann, Tom N.
المصدر: Chem. 10(2)
وصف الملف: electronic
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2Academic Journal
المؤلفون: STEFFEN, Candy, MANOHARAN, Ganesh Babu, PAVIC, Karolina, Yeste-Vázquez, Alejandro, Knuuttila, Matias, Arora, Neha, Zhou, Yong, Härmä, Harri, GAIGNEAUX, Anthoula, Grossmann, Tom N, ABANKWA, Daniel
المصدر: Communications Biology, 7 (1), 837 (2024-07-09)
مصطلحات موضوعية: Peptides, Proto-Oncogene Proteins p21(ras), Galectin 1, HRAS protein, human, Humans, Proto-Oncogene Proteins p21(ras)/chemistry, Galectin 1/chemistry, Galectin 1/genetics, Protein Binding, Signal Transduction, Peptides/chemistry, Medicine (miscellaneous), Biochemistry, Genetics and Molecular Biology (all), Life sciences, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire
Relation: https://www.nature.com/articles/s42003-024-06523-9.pdf; urn:issn:2399-3642; https://orbilu.uni.lu/handle/10993/61635; info:hdl:10993/61635; https://orbilu.uni.lu/bitstream/10993/61635/1/SteffenCL2024.pdf; info:pmid:38982284
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3Academic Journal
المؤلفون: Yeste‐Vázquez, Alejandro, Paulussen, Felix M., Wendt, Mathias, Klintrot, Rasmus, Schulte, Clemens, Wallraven, Kerstin, van Gijzel, Lieke, Simeonov, Boris, van der Gaag, Maurice, Gerber, Alan, Maric, Hans M., Hennig, Sven, Grossmann, Tom N.
المساهمون: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, KWF Kankerbestrijding, H2020 European Research Council
المصدر: Angewandte Chemie International Edition ; volume 63, issue 47 ; ISSN 1433-7851 1521-3773
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4Academic Journal
المؤلفون: Anbuhl, Stephanie M., Dervillez, Xavier, Neubacher, Saskia, Schriek, Angela I., Bobkov, Vladimir, de Taeye, Steven W., Szpakowska, Martyna, Siderius, Marco, Grossmann, Tom N., Chevigné, Andy, Smit, Martine J., Heukers, Raimond
المصدر: Anbuhl , S M , Dervillez , X , Neubacher , S , Schriek , A I , Bobkov , V , de Taeye , S W , Szpakowska , M , Siderius , M , Grossmann , T N , Chevigné , A , Smit , M J & Heukers , R 2024 , ' Multivalent CXCR4-targeting nanobody formats differently affect affinity, receptor clustering, and antagonism ' , Biochemical Pharmacology , vol. 227 , 116457 . https://doi.org/10.1016/j.bcp.2024.116457
مصطلحات موضوعية: Affinity, Avidity, CXCR4, Multivalency, Nanobody, Nanobody-Fc
الاتاحة: https://research.vu.nl/en/publications/68ea7bdf-5424-4c31-9a82-b25b293a314a
https://doi.org/10.1016/j.bcp.2024.116457
https://hdl.handle.net/1871.1/68ea7bdf-5424-4c31-9a82-b25b293a314a
http://www.scopus.com/inward/record.url?scp=85200331203&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85200331203&partnerID=8YFLogxK -
5Academic Journal
المؤلفون: Durukan, Canan, Arbore, Federica, Klintrot, Rasmus, Bigiotti, Carlo, Ilie, Ioana M, Vreede, Jocelyne, Grossmann, Tom N, Hennig, Sven
المصدر: Durukan , C , Arbore , F , Klintrot , R , Bigiotti , C , Ilie , I M , Vreede , J , Grossmann , T N & Hennig , S 2024 , ' Binding dynamics of a stapled peptide targeting the transcription factor NF-Y ' , ChemBioChem , vol. 25 , no. 9 , e202400020 , pp. 1-9 . https://doi.org/10.1002/cbic.202400020
الاتاحة: https://research.vu.nl/en/publications/8e3100ba-ce60-4382-b279-923dbcc2e33b
https://doi.org/10.1002/cbic.202400020
https://hdl.handle.net/1871.1/8e3100ba-ce60-4382-b279-923dbcc2e33b
http://www.scopus.com/inward/record.url?scp=85189134883&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85189134883&partnerID=8YFLogxK -
6Academic Journal
المؤلفون: Reissland, Michaela, Hartmann, Oliver, Tauch, Saskia, Bugter, Jeroen M., Prieto-Garcia, Cristian, Schulte, Clemens, Loebbert, Sinah, Solvie, Daniel, Bitman-Lotan, Eliya, Narain, Ashwin, Jacomin, Anne-Claire, Schuelein-Voelk, Christina, Fuss, Carmina T., Pahor, Nikolett, Ade, Carsten, Buck, Viktoria, Potente, Michael, Li, Vivian, Beliu, Gerti, Wiegering, Armin, Grossmann, Tom, Eilers, Martin, Wolf, Elmar, Maric, Hans, Rosenfeldt, Mathias, Maurice, Madelon M., Dikic, Ivan, Gallant, Peter, Orian, Amir, Diefenbacher, Markus E.
المصدر: Oncogene ; volume 43, issue 50, page 3645-3659 ; ISSN 0950-9232 1476-5594
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7Academic Journal
المؤلفون: Grossmann, Tom N., Durukan, Canan
المساهمون: Fonds der Chemischen Industrie, Deutsche Forschungsgemeinschaft, European Research Council, H2020 European Research Council, Exacte en Natuurwetenschappen, KWF Kankerbestrijding, AstraZeneca, Bayer CropScience, Bayer HealthCare, Boehringer Ingelheim, Merck KGaA, Max-Planck-Gesellschaft
المصدر: Synlett ; ISSN 0936-5214 1437-2096
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8Academic Journal
المؤلفون: Durukan, Canan, Grossmann, Tom N.
المصدر: Synlett; Jan2025, Vol. 36 Issue 2, p119-128, 10p
مصطلحات موضوعية: CHEMICAL modification of proteins, MOLECULAR size, BIOMIMETIC chemicals, PROTEIN engineering, BIOTECHNOLOGY, MOLECULAR recognition
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9Academic Journal
المؤلفون: Paulussen, Felix M., Grossmann, Tom N.
المصدر: Paulussen , F M & Grossmann , T N 2023 , ' Peptide-based covalent inhibitors of protein–protein interactions ' , Journal of Peptide Science , vol. 29 , no. 1 , e3457 . https://doi.org/10.1002/psc.3457
مصطلحات موضوعية: bioconjugation, new modalities, peptidomimetics, proteomimetics, structure-based design
الاتاحة: https://research.vu.nl/en/publications/9804ed80-4953-4097-b83d-d434efd97783
https://doi.org/10.1002/psc.3457
https://hdl.handle.net/1871.1/9804ed80-4953-4097-b83d-d434efd97783
http://www.scopus.com/inward/record.url?scp=85141696827&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85141696827&partnerID=8YFLogxK -
10Academic Journal
المؤلفون: McLoughlin, Niall M., Albers, Marvin A., Collado Camps, Estel, Paulus, Jannik, Ran, Youri A., Neubacher, Saskia, Hennig, Sven, Brock, Roland, Grossmann, Tom N.
المصدر: McLoughlin , N M , Albers , M A , Collado Camps , E , Paulus , J , Ran , Y A , Neubacher , S , Hennig , S , Brock , R & Grossmann , T N 2023 , ' Environment-Responsive Peptide Dimers Bind and Stabilize Double-Stranded RNA ' , Angewandte Chemie. International Edition , vol. 62 , no. 41 , e202308028 . https://doi.org/10.1002/anie.202308028
مصطلحات موضوعية: Reversible Dimerization, RNA Delivery, RNA Stabilization, RNA/Peptide Complex, TAV2b
الاتاحة: https://research.vu.nl/en/publications/d3374915-14d6-4c30-addf-54c84519729e
https://doi.org/10.1002/anie.202308028
https://hdl.handle.net/1871.1/d3374915-14d6-4c30-addf-54c84519729e
http://www.scopus.com/inward/record.url?scp=85169167708&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85169167708&partnerID=8YFLogxK -
11Academic Journal
المؤلفون: Kiehstaller, Sebastian, Hutchins, George H., Amore, Alessia, Gerber, Alan, Ibrahim, Mohamed, Hennig, Sven, Neubacher, Saskia, Grossmann, Tom N.
المصدر: Kiehstaller , S , Hutchins , G H , Amore , A , Gerber , A , Ibrahim , M , Hennig , S , Neubacher , S & Grossmann , T N 2023 , ' Bicyclic Engineered Sortase A Performs Transpeptidation under Denaturing Conditions ' , Bioconjugate chemistry , vol. 34 , no. 6 , pp. 1114-1121 . https://doi.org/10.1021/acs.bioconjchem.3c00151
الاتاحة: https://research.vu.nl/en/publications/ce68c81f-f931-4ebd-93ed-e2d4861cf034
https://doi.org/10.1021/acs.bioconjchem.3c00151
https://hdl.handle.net/1871.1/ce68c81f-f931-4ebd-93ed-e2d4861cf034
http://www.scopus.com/inward/record.url?scp=85163148932&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85163148932&partnerID=8YFLogxK -
12Academic Journal
المؤلفون: Brauckhoff, Nicolas, Fang, Laura, Haim, Anissa, Grossmann, Tom N.
المصدر: Brauckhoff , N , Fang , L , Haim , A & Grossmann , T N 2023 , ' Non-enzymatic protein templates amide bond formation and provides catalytic turnover ' , Chemical Communications , vol. 2023 , no. 5 , pp. 5241–5244 . https://doi.org/10.1039/d3cc00514c
الاتاحة: https://research.vu.nl/en/publications/e062b5d6-c362-4675-80ca-8516225022ba
https://doi.org/10.1039/d3cc00514c
https://hdl.handle.net/1871.1/e062b5d6-c362-4675-80ca-8516225022ba
http://www.scopus.com/inward/record.url?scp=85153619808&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85153619808&partnerID=8YFLogxK -
13Academic Journal
المؤلفون: MANOHARAN, Ganesh Babu, STEFFEN, Candy, PAVIC, Karolina, Yeste-Vázquez, Alejandro, Knuuttila, Matias, Arora, Neha, Zhou, Yong, Härmä, Harri, GAIGNEAUX, Anthoula, Grossmann, Tom N., ABANKWA, Daniel
المصدر: Cold Spring Harbor Laboratory (2023-09-08)
مصطلحات موضوعية: Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire
Relation: https://orbilu.uni.lu/handle/10993/59296; info:hdl:10993/59296; https://orbilu.uni.lu/bitstream/10993/59296/1/Manoharan%2c%20Steffen%20et%20al%2c%202023.pdf
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14Conference
المؤلفون: MANOHARAN, Ganesh Babu, PAVIC, Karolina, Yeste Vazquez, Alejandro, Knuuttila, Matias, Grossmann, Tom N., ABANKWA, Daniel
المساهمون: STEFFEN, Candy
المصدر: Small G proteins in cellular signalling and disease, Liverpool, United Kingdom [GB], 12.09.2022-15.09.2022
مصطلحات موضوعية: Ras, Galectin-1, Peptide, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire
Relation: https://orbilu.uni.lu/handle/10993/59598; info:hdl:10993/59598; https://orbilu.uni.lu/bitstream/10993/59598/1/Abstract.docx
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15Academic Journal
المصدر: Koelman , E M R , Yeste-Vázquez , A & Grossmann , T N 2022 , ' Targeting the interaction of β-catenin and TCF/LEF transcription factors to inhibit oncogenic Wnt signaling ' , Bioorganic and Medicinal Chemistry , vol. 70 , 116920 , pp. 1-8 . https://doi.org/10.1016/j.bmc.2022.116920
مصطلحات موضوعية: Cancer, Peptidomimetic, Protein-protein interaction, Proteomimetic, Structure-based design, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being
الاتاحة: https://research.vu.nl/en/publications/ed1b129b-bf67-433c-8e24-04c6f379ffa3
https://doi.org/10.1016/j.bmc.2022.116920
https://hdl.handle.net/1871.1/ed1b129b-bf67-433c-8e24-04c6f379ffa3
http://www.scopus.com/inward/record.url?scp=85134295835&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85134295835&partnerID=8YFLogxK -
16Academic Journal
المؤلفون: Schouten, Gina K., Paulussen, Felix M., Kuipers, Oscar P., Bitter, Wilbert, Grossmann, Tom N., van Ulsen, Peter
المصدر: Schouten , G K , Paulussen , F M , Kuipers , O P , Bitter , W , Grossmann , T N & van Ulsen , P 2022 , ' Stapling of Peptides Potentiates : The Antibiotic Treatment of Acinetobacter baumannii In Vivo ' , Antibiotics , vol. 11 , no. 2 , 273 , pp. 1-16 . https://doi.org/10.3390/antibiotics11020273
مصطلحات موضوعية: Stapled antimicrobial peptides, Synergy, Zebrafish larvae infection model
الاتاحة: https://research.vu.nl/en/publications/dcc37fa0-2324-46df-bada-3c968f183512
https://doi.org/10.3390/antibiotics11020273
https://hdl.handle.net/1871.1/dcc37fa0-2324-46df-bada-3c968f183512
http://www.scopus.com/inward/record.url?scp=85125066326&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85125066326&partnerID=8YFLogxK -
17Academic Journal
المؤلفون: Paulussen, Felix M., Schouten, Gina K., Moertl, Carolin, Verheul, Jolanda, Hoekstra, Irma, Koningstein, Gregory M., Hutchins, George H., Alkir, Aslihan, Luirink, Rosa A., Geerke, Daan P., Van Ulsen, Peter, Den Blaauwen, Tanneke, Luirink, Joen, Grossmann, Tom N.
المصدر: Paulussen , F M , Schouten , G K , Moertl , C , Verheul , J , Hoekstra , I , Koningstein , G M , Hutchins , G H , Alkir , A , Luirink , R A , Geerke , D P , Van Ulsen , P , Den Blaauwen , T , Luirink , J & Grossmann , T N 2022 , ' Covalent Proteomimetic Inhibitor of the Bacterial FtsQB Divisome Complex ' , Journal of the American Chemical Society , vol. 144 , no. 33 , pp. 15303-15313 . https://doi.org/10.1021/jacs.2c06304
الاتاحة: https://research.vu.nl/en/publications/3323f664-6dca-4402-80d9-2d08dfc219fe
https://doi.org/10.1021/jacs.2c06304
https://hdl.handle.net/1871.1/3323f664-6dca-4402-80d9-2d08dfc219fe
http://www.scopus.com/inward/record.url?scp=85136282983&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85136282983&partnerID=8YFLogxK -
18Academic Journal
المؤلفون: Wendt, Mathias, Bellavita, Rosa, Gerber, Alan, Efrém, Nina-Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez-Chantada, Mercedes, Chiarpari, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N.
المساهمون: Wendt, Mathia, Bellavita, Rosa, Gerber, Alan, Efrém, Nina-Louisa, van Ramshorst, Thirza, Pearce, Nicholas M., Davey, Paul R. J., Everard, Isabel, Vazquez-Chantada, Mercede, Chiarpari, Elisabetta, Grieco, Paolo, Hennig, Sven, Grossmann, Tom N.
مصطلحات موضوعية: Thioether crosslink, Wnt Signaling, macrocycle, peptidomimetic, protein-protein interaction
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000647214600001; journal:ANGEWANDTE CHEMIE. INTERNATIONAL EDITION; http://hdl.handle.net/11588/850664; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85105037234
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19
المؤلفون: Glas, Adrian, Wamhoff, Eike-Christian, Krüger, Dennis M., Rademacher, Christoph, Grossmann, Tom N.
المصدر: Chemistry - A European Journal. 23(64):16157-16161
مصطلحات موضوعية: F-19 NMR spectroscopy, binding kinetics, cyclic peptides, molecular dynamics simulation, peptidomimetics
وصف الملف: electronic
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20Academic Journal
المؤلفون: Bernús, Miguel, Mazzarella, Daniele, Stanić, Jelena, Zhai, Ziran, Yeste-Vázquez, Alejandro, Boutureira, Omar, Gargano, Andrea F. G., Grossmann, Tom N., Noël, Timothy
المصدر: Nature Synthesis ; volume 3, issue 2, page 277-277 ; ISSN 2731-0582