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المؤلفون: Gregory L. Finch, Stephanie F. Greene
المصدر: Translational Medicine ISBN: 9781003124542
Translational Medicineمصطلحات موضوعية: Inhalation, business.industry, Anesthesia, Medicine, business
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2Academic Journal
المؤلفون: Roma Kalra, Shashi P Singh, Susan M Savage, Gregory L Finch, Mohan L Sopori
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1090.3289; http://jpet.aspetjournals.org/content/jpet/293/1/166.full.pdf
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المؤلفون: Pamela Strode, Stephen E. Zale, Marc Wolfgang, Hagop Youssoufian, Iulian Bobe, Maggie Liu, Matthew Peterson, Gregory L. Finch, Henry A. Havel
المصدر: The AAPS Journal. 18:1373-1378
مصطلحات موضوعية: 0301 basic medicine, Biological Products, Engineering, Drug Industry, business.industry, Pharmacology toxicology, Pharmaceutical Science, Nanotechnology, 02 engineering and technology, 021001 nanoscience & nanotechnology, Quality by Design, Bench to bedside, 03 medical and health sciences, Drug Delivery Systems, Nanomedicine, 030104 developmental biology, New product development, Animals, Humans, Nanoparticles, Engineering ethics, Product (category theory), 0210 nano-technology, business, Drug Approval
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المؤلفون: Michael W. Leach, Leslie G. Lorello, Gregory L. Finch, Sharon L. Ripp, Ahmed M. Shoieb, Shawn P. O'Neil, Jameel Syed, Zaher A. Radi, Matthew S. Thompson, Mazin Derzi
المصدر: Regulatory Toxicology and Pharmacology. 112:104587
مصطلحات موضوعية: Male, musculoskeletal diseases, medicine.drug_class, 010501 environmental sciences, Pharmacology, Toxicology, Monoclonal antibody, 030226 pharmacology & pharmacy, 01 natural sciences, 03 medical and health sciences, 0302 clinical medicine, In vivo, Adalimumab, medicine, Animals, Humans, media_common.cataloged_instance, Toxicokinetics, Tissue Distribution, European Union, European union, skin and connective tissue diseases, Biosimilar Pharmaceuticals, 0105 earth and related environmental sciences, media_common, business.industry, Biosimilar, U937 Cells, General Medicine, United States, Macaca fascicularis, Toxicity, Female, Tumor necrosis factor alpha, business, medicine.drug
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المؤلفون: Animesh Goswami, Andrew S. Wells, David Entwistle, Nicholas J. Turner, Robert K. Sato, Wong John Wing, Stefan Mix, Keith R. Fandrick, Thomas S. Moody, Timothy James-Norman Watson, Peter C. Michels, Long Pang, Gregory L. Finch, Heewon Lee
المصدر: Organic Process Research & Development. 20:594-601
مصطلحات موضوعية: Active ingredient, 010405 organic chemistry, Agrochemical, business.industry, Computer science, Process (engineering), Organic Chemistry, Risk-based testing, Nanotechnology, 010402 general chemistry, 01 natural sciences, Dosage form, 0104 chemical sciences, Drug quality, Bioprocess engineering, Biocatalysis, Biochemical engineering, Physical and Theoretical Chemistry, business
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المؤلفون: Karen E. Rule, Gregory L. Finch, Michael H.I. Shiue, Paul R. Brown, Stephane Thibault, Michael W. Leach, David W. Clarke, Marjorie A. Peraza
المصدر: Regulatory toxicology and pharmacology : RTP. 95
مصطلحات موضوعية: 0301 basic medicine, Male, Vascular Endothelial Growth Factor A, genetic structures, Bevacizumab, Colorectal cancer, Angiogenesis Inhibitors, Pharmacology, Toxicology, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Antineoplastic Agents, Immunological, In vivo, Human Umbilical Vein Endothelial Cells, Medicine, media_common.cataloged_instance, Animals, Humans, Protein Isoforms, European union, Lung cancer, Biosimilar Pharmaceuticals, media_common, Cell Proliferation, Molecular Structure, business.industry, General Medicine, Organ Size, medicine.disease, Vascular endothelial growth factor, Vascular endothelial growth factor A, Macaca fascicularis, 030104 developmental biology, chemistry, Liver, 030220 oncology & carcinogenesis, Toxicity, Female, business, medicine.drug, Protein Binding
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المؤلفون: Gwendolyn D. Fate, Gregory L. Finch, Steven Bailey, Daniel Morton, Peter J. Thomford, Christopher Houle, Prashant R. Nambiar, Leland Wayne Dochterman
المصدر: Toxicologic Pathology. 43:354-365
مصطلحات موضوعية: Male, medicine.medical_specialty, Pathology, Carcinogenicity Tests, Urinary system, Kaplan-Meier Estimate, Urinalysis, urologic and male genital diseases, Toxicology, Pathology and Forensic Medicine, Rats, Sprague-Dawley, Eating, Tubular adenoma, Internal medicine, Nitriles, Animals, Medicine, Thyroid Neoplasms, Molecular Biology, Kidney, Urinary bladder, Dose-Response Relationship, Drug, business.industry, Body Weight, Liver Neoplasms, Thyroid, Cell Biology, Transitional epithelium, Hepatocellular adenoma, medicine.disease, Survival Analysis, Kidney Neoplasms, digestive system diseases, Rats, Transitional cell carcinoma, medicine.anatomical_structure, Endocrinology, Urinary Bladder Neoplasms, Carcinogens, Pyrazoles, Reverse Transcriptase Inhibitors, Female, business
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8Comparative Nonclinical Assessments of the Proposed Biosimilar PF-05280586 and Rituximab (MabThera®)
المؤلفون: Chee-Keng Ng, Mark Collinge, Stephen A. Ploch, Zaher A. Radi, Susan Hurst, Niraj Tripathi, Joshua Arrington, Amy C. Shen, Gregory L. Finch, Michael W. Leach, Norimitsu Shirai, Anne M. Ryan, Sharon A. Sokolowski, Thomas Cummings, Sarah A. Stephenson
المصدر: Toxicologic Pathology. 42:1069-1081
مصطلحات موضوعية: Male, Endpoint Determination, Pharmacology, Toxicology, Pathology and Forensic Medicine, Antibodies, Monoclonal, Murine-Derived, Pharmacokinetics, Animals, Medicine, Dosing, Anti cd20, Biosimilar Pharmaceuticals, Molecular Biology, B-Lymphocytes, Dose-Response Relationship, Drug, biology, business.industry, Reproducibility of Results, Biosimilar, Cell Biology, Antigens, CD20, Peripheral blood, Macaca fascicularis, Pharmacodynamics, biology.protein, Female, Rituximab, Antibody, business, medicine.drug
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المؤلفون: Peter C. Michels, Andrew S. Wells, John W. Wong, Gregory L. Finch
المصدر: Organic Process Research & Development. 16:1986-1993
مصطلحات موضوعية: Active ingredient, media_common.quotation_subject, Organic Chemistry, Nanotechnology, law.invention, Drug quality, Patient safety, Risk analysis (engineering), law, CLARITY, Quality (business), Business, Physical and Theoretical Chemistry, media_common
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المؤلفون: Gregg D. Cappon, Mark E. Hurtt, Sarah N. Campion, Anthony Harrison, Gregory L. Finch, Christopher J. Bowman
المصدر: Birth Defects Research Part B: Developmental and Reproductive Toxicology. 95:250-261
مصطلحات موضوعية: Embryology, Fetus, Reverse-transcriptase inhibitor, business.industry, Health, Toxicology and Mutagenesis, Developmental toxicity, Physiology, Organogenesis, Toxicology, Oral gavage, Anesthesia, Toxicity, medicine, Gestation, Lersivirine, business, Developmental Biology, medicine.drug
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11
المؤلفون: Gregg D. Cappon, Christopher J. Bowman, Sarah N. Campion, Elise M. Lewis, Gregory L. Finch, Mark E. Hurtt, Gary W. Chmielewski
المصدر: Birth Defects Research Part B: Developmental and Reproductive Toxicology. 95:225-230
مصطلحات موضوعية: Embryology, medicine.medical_specialty, Pregnancy, Reverse-transcriptase inhibitor, Health, Toxicology and Mutagenesis, Developmental toxicity, Mammalian embryology, Embryo, Biology, Toxicology, medicine.disease, Endocrinology, Internal medicine, medicine, Gestation, Lersivirine, Dosing, Developmental Biology, medicine.drug
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المؤلفون: Gregg D. Cappon, Donald Newgreen, Richard H. Alper, Brian Bush, Gregory L. Finch
المصدر: European Journal of Pharmacology. 579:225-228
مصطلحات موضوعية: Male, medicine.medical_specialty, Tolterodine Tartrate, Side effect, Phenylpropanolamine, Scopolamine, Central nervous system, Muscarinic Antagonists, Pharmacology, Cresols, Mice, Random Allocation, Species Specificity, Memory, Internal medicine, Muscarinic acetylcholine receptor, Avoidance Learning, medicine, Animals, Benzhydryl Compounds, Oxybutynin, Dose-Response Relationship, Drug, Memoria, medicine.disease, Endocrinology, medicine.anatomical_structure, Overactive bladder, Tolterodine, Psychology, medicine.drug
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المؤلفون: Kristen J Nikula, Gregory L. Finch, Larry E. Bowen, Bonnie J Wayne, Thomas H. March, C. H. Hobbs
المصدر: COPD: Journal of Chronic Obstructive Pulmonary Disease. 2:289-302
مصطلحات موضوعية: Inhalation exposure, Pulmonary and Respiratory Medicine, medicine.medical_specialty, COPD, Pathology, Inhalation, business.industry, medicine.medical_treatment, Intraperitoneal injection, Retinoic acid, respiratory system, medicine.disease, chemistry.chemical_compound, Endocrinology, chemistry, Inbred strain, Tretinoin, Internal medicine, Medicine, Analysis of variance, business, medicine.drug
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المؤلفون: Kristen J. Nikula, Sheila S. Snow, Carmen S. Tellez, Gregory L. Finch, William A. Palmisano, Steven A. Belinsky
المصدر: Carcinogenesis. 23:335-339
مصطلحات موضوعية: Male, Cancer Research, Pathology, medicine.medical_specialty, Lung Neoplasms, Time Factors, Tumor suppressor gene, Bisulfite sequencing, Biology, medicine.disease_cause, medicine, Animals, Humans, Gene silencing, Cyclin-Dependent Kinase Inhibitor p16, Carcinogen, Vehicle Emissions, Dose-Response Relationship, Drug, Reverse Transcriptase Polymerase Chain Reaction, Estrogen Receptor alpha, Exons, General Medicine, Methylation, DNA Methylation, Carbon, Rats, Inbred F344, Rats, Receptors, Estrogen, DNA methylation, Carcinogens, Cancer research, CpG Islands, Female, Beryllium, Carcinogenesis, Estrogen receptor alpha
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المصدر: Inhalation Toxicology. 14:1187-1213
مصطلحات موضوعية: medicine.medical_specialty, Pathology, Time Factors, Health, Toxicology and Mutagenesis, Toxicology, Proinflammatory cytokine, Mice, chemistry.chemical_compound, Ozone, Superoxides, Internal medicine, Lactate dehydrogenase, Endopeptidases, Macrophages, Alveolar, medicine, Animals, Lung, Inhalation Exposure, COPD, medicine.diagnostic_test, Chemistry, Body Weight, Interleukin, Glutathione, respiratory system, medicine.disease, respiratory tract diseases, Bronchoalveolar lavage, Endocrinology, Pulmonary Emphysema, Cytokines, Alkaline phosphatase, Female, Tobacco Smoke Pollution, Histopathology, Bronchoalveolar Lavage Fluid
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المؤلفون: Beverly Ingram, Chee-Keng Ng, Lynne A. Bui, Ira Jacobs, Anne M. Ryan, Carol F. Kirchhoff, Susan Hurst, Gregory L. Finch
المصدر: Drug discovery today. 20
مصطلحات موضوعية: Pharmacology, Quality Control, Consumer Product Safety, Therapeutic equivalency, Drug Industry, Molecular Structure, Process (engineering), business.industry, Manufacturing process, Drug Evaluation, Preclinical, Guidance documents, Biosimilar, Nanotechnology, Structure-Activity Relationship, Risk analysis (engineering), Therapeutic Equivalency, Risk Factors, Drug Discovery, Key (cryptography), Medicine, Animals, Humans, business, Biosimilar Pharmaceuticals
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المؤلفون: Thomas H. March, C. H. Hobbs, Fletcher F. Hahn, Gregory L. Finch, Edward B. Barr, Margaret G Ménache, Kristen J. Nikula
المصدر: Toxicological Sciences. 51:289-299
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Neutrophils, Ratón, Stereology, Weight Gain, Toxicology, Muscle hypertrophy, Mice, Species Specificity, Smoke, Tobacco, Parenchyma, Animals, Medicine, Lung, Crosses, Genetic, Mice, Inbred C3H, business.industry, Macrophages, Respiratory disease, respiratory system, medicine.disease, Rats, Inbred F344, Rats, Mice, Inbred C57BL, Disease Models, Animal, Plants, Toxic, medicine.anatomical_structure, Pulmonary Emphysema, Toxicity, Female, Histopathology, Disease Susceptibility, business
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المؤلفون: Gregory L. Finch, Werner Burkart, Thomas S. Jung
المصدر: Science of The Total Environment. 205:51-70
مصطلحات موضوعية: Engineering, Environmental Engineering, Risk Assessment, Xenobiotics, Toxicology, Neoplasms, Occupational Exposure, Low exposure, Animals, Humans, Environmental Chemistry, Mode of action, Set (psychology), Waste Management and Disposal, business.industry, Low-Level Radiation, Environmental Exposure, Environmental exposure, Models, Theoretical, Pollution, United States, Gene Expression Regulation, Neoplastic, Tumour therapy, Risk analysis (engineering), Action (philosophy), Metals, Mutation, Environmental Pollutants, Public Health, business, Risk assessment, Radioactive Pollutants
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المؤلفون: D. S. Swafford, Kristen J. Nikula, Gregory Kelly, Charles E. Mitchell, Marshall W. Anderson, Gregory L. Finch, Fletcher F. Hahn, Steven A. Belinsky
المصدر: Environmental Health Perspectives
مصطلحات موضوعية: Mutation, Lung Neoplasms, Transition (genetics), DNA damage, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, Single-strand conformation polymorphism, Biology, Gene mutation, Genes, p53, medicine.disease_cause, Molecular biology, Rats, Genes, ras, Proto-Oncogene Proteins, medicine, Animals, Mutation frequency, Protein stabilization, Gene, Research Article, DNA Damage
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20
المصدر: Toxicologic Pathology. 25:2-12
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Pathology, medicine.medical_specialty, Mice, Inbred A, 040301 veterinary sciences, Berylliosis, Lymphocyte Activation, Toxicology, 030226 pharmacology & pharmacy, Pathology and Forensic Medicine, 0403 veterinary science, Pathogenesis, Mice, 03 medical and health sciences, 0302 clinical medicine, Antigen, Administration, Inhalation, medicine, Animals, Molecular Biology, Pneumonitis, B-Lymphocytes, Mice, Inbred C3H, Granuloma, Lung, Inhalation, business.industry, Respiratory disease, Pneumonia, 04 agricultural and veterinary sciences, Cell Biology, medicine.disease, medicine.anatomical_structure, Chronic Disease, Immunology, Female, Beryllium, business, Beryllium Disease