المؤلفون: Amy Easton, Marianne L. Jensen, Congwei Wang, Peter H. Hagedorn, Yuwen Li, Michael Weed, Jere E. Meredith, Valerie Guss, Kelli Jones, Martin Gill, Carol Krause, Jeffrey M. Brown, Lisa Hunihan, Joanne Natale, Alda Fernandes, Yifeng Lu, Joe Polino, Mark Bookbinder, Greg Cadelina, Yulia Benitex, Ramola Sane, John Morrison, Dieter Drexler, Stephen E. Mercer, Charlotte Bon, Nikhil J. Pandya, Ravi Jagasia, Tai-Hsien Ou Yang, Tania Distler, Fiona Grüninger, Michael Meldgaard, Marco Terrigno, John E. Macor, Charles F. Albright, James Loy, Anja M. Hoeg, Richard E. Olson, Angela M. Cacace

المصدر: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 625-642 (2022)

مصطلحات موضوعية: MT: oligonucleotides: therapies and applications, MAPT, tau, tauopathies, neurodegeneration, antisense oligonucleotides, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253122001962; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/b93757f19dfa46c987c592a3e606bdbe

المؤلفون: Michael Berlin, Jennifer Cantley, Mark Bookbinder, Elizabeth Bortolon, Fabio Broccatelli, Greg Cadelina, Emily W. Chan, Huifen Chen, Xin Chen, Yunxing Cheng, Tommy K. Cheung, Kim Davenport, Dean DiNicola, Debbie Gordon, Brian D. Hamman, Alicia Harbin, Roy Haskell, Mingtao He, Alison J. Hole, Thomas Januario, Philip S. Kerry, Stefan G. Koenig, Limei Li, Mark Merchant, Inmaculada Pérez-Dorado, Jennifer Pizzano, Connor Quinn, Christopher M. Rose, Emma Rousseau, Leofal Soto, Leanna R. Staben, Hongming Sun, Qingping Tian, Jing Wang, Weifeng Wang, Crystal S. Ye, Xiaofen Ye, Penghong Zhang, Yuhui Zhou, Robert Yauch, Peter S. Dragovich

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Immunology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, thus highly dependent, pd analysis established, also selectively impair, >) also supported, compounds identified protacs, selectively degraded brm, type calu6 line, h1944 “ brg1, fold degradation selectivity, protacs targeting brm, also known, brm protein, brm (<, vivo <, sw1573 cell, subsequent pk, plau <, mrna associated, molecules exhibit

Relation: https://figshare.com/articles/journal_contribution/PROTACs_Targeting_BRM_SMARCA2_Afford_Selective_i_In_Vivo_i_Degradation_over_BRG1_SMARCA4_and_Are_Active_in_BRG1_Mutant_Xenograft_Tumor_Models/24949319

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01781.s001
https://figshare.com/articles/journal_contribution/PROTACs_Targeting_BRM_SMARCA2_Afford_Selective_i_In_Vivo_i_Degradation_over_BRG1_SMARCA4_and_Are_Active_in_BRG1_Mutant_Xenograft_Tumor_Models/24949319

المؤلفون: Kathryn Smith, Andrea Lopez-Arroyo, Jason Berk, Peter Hegan, Peter Nower, Samantha Tice, Aurelie Moutran, Jennifer Pizzano, Amanda Dowtin, Mark Bookbinder, Elizabeth Bortolon, Greg Cadelina, Fazlul Karim, Katie Digianantonio, Miklos Bekes, Jesus Medina

المصدر: Molecular Cancer Research. 21:PR09-PR09

مصطلحات موضوعية: Cancer Research, Oncology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6662ff725ab919eef766a4181d81492
https://doi.org/10.1158/1557-3125.ras23-pr09

المؤلفون: Amy Easton, Marianne L. Jensen, Congwei Wang, Peter H. Hagedorn, Yuwen Li, Michael Weed, Jere E. Meredith, Valerie Guss, Kelli Jones, Martin Gill, Carol Krause, Jeffrey M. Brown, Lisa Hunihan, Joanne Natale, Alda Fernandes, Yifeng Lu, Joe Polino, Mark Bookbinder, Greg Cadelina, Yulia Benitex, Ramola Sane, John Morrison, Dieter Drexler, Stephen E. Mercer, Charlotte Bon, Nikhil J. Pandya, Ravi Jagasia, Tai-Hsien Ou Yang, Tania Distler, Fiona Grüninger, Michael Meldgaard, Marco Terrigno, John E. Macor, Charles F. Albright, James Loy, Anja M. Hoeg, Richard E. Olson, Angela M. Cacace

المصدر: Molecular therapy. Nucleic acids. 29

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc4302dcff03d41215dd8c99c37d729
https://pubmed.ncbi.nlm.nih.gov/36090761

المؤلفون: Greg Cadelina, J.C. Lopez-Talavera, Ramon Martí, Joan Genescà, Moises Martinez, Rafael Esteban, Roberto J. Groszmann, Antonio González, Jaime Guardia, Encarna Varela, Rosa M. Segura, Robert Catalan

المصدر: American Journal of Gastroenterology. 94:169-177

مصطلحات موضوعية: Liver Cirrhosis, Male, medicine.medical_specialty, Mean arterial pressure, Cirrhosis, Vasopressins, Blood Pressure, Nitric Oxide, Plasma renin activity, Nitric oxide, Interferon-gamma, chemistry.chemical_compound, Internal medicine, Renin, Ascites, medicine, Humans, Aldosterone, Hepatic encephalopathy, Nitrites, Aged, Nitrates, Hepatology, Interleukin-6, Tumor Necrosis Factor-alpha, business.industry, Gastroenterology, Middle Aged, medicine.disease, Endotoxins, Blood pressure, Endocrinology, chemistry, Hepatic Encephalopathy, Hyperdynamic circulation, Female, medicine.symptom, business, Interleukin-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8163642495e4d334981c1654e6b3c27
https://doi.org/10.1111/j.1572-0241.1999.00790.x

المؤلفون: Guadalupe Garcia-Tsao, S. Das, Sheldon Milstien, Reiner Wiest, Roberto J. Groszmann, Greg Cadelina

المصدر: The Journal of clinical investigation. 104(9)

مصطلحات موضوعية: Male, medicine.medical_specialty, Endothelium, Liver Cirrhosis, Experimental, Nitric Oxide, Article, Nitric oxide, Methoxamine, Contractility, Rats, Sprague-Dawley, chemistry.chemical_compound, Enos, Internal medicine, Pressure, Medicine, Mesenteric lymph nodes, Animals, Protein Isoforms, Vasoconstrictor Agents, Mesenteric arteries, biology, Dose-Response Relationship, Drug, business.industry, Tumor Necrosis Factor-alpha, General Medicine, biology.organism_classification, Mesenteric Arteries, Rats, Nitric oxide synthase, Perfusion, medicine.anatomical_structure, Endocrinology, chemistry, Vasoconstriction, Bacterial Translocation, biology.protein, Lymph Nodes, Stress, Mechanical, medicine.symptom, Nitric Oxide Synthase, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef1e3ec6bf26c6cf585db0f435f4738
https://pubmed.ncbi.nlm.nih.gov/10545521

المؤلفون: Roberto J. Groszmann, Vijay Shah, Greg Cadelina, William C. Sessa, Guillermo García-Cardeña, Reiner Wiest

المصدر: The American journal of physiology. 277(2)

مصطلحات موضوعية: Male, medicine.medical_specialty, Nitric Oxide Synthase Type III, Physiology, Lactams, Macrocyclic, Vasodilator Agents, Vasodilation, Biology, In Vitro Techniques, Nitric Oxide, Nitric oxide, Methoxamine, Rats, Sprague-Dawley, chemistry.chemical_compound, Enos, Physiology (medical), Internal medicine, Hypertension, Portal, medicine, Benzoquinones, Animals, Vasoconstrictor Agents, Tissue Distribution, HSP90 Heat-Shock Proteins, Splanchnic Circulation, Hepatology, Microcirculation, Gastroenterology, Quinones, medicine.disease, biology.organism_classification, Acetylcholine, Rats, Nitric oxide synthase, Endocrinology, chemistry, biology.protein, Portal hypertension, Blood Vessels, Sodium nitroprusside, medicine.symptom, Nitric Oxide Synthase, Vasoconstriction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c9fed2a2a0ab3efcfb34df1ad3e003
https://pubmed.ncbi.nlm.nih.gov/10444461

المؤلفون: Greg Cadelina, Reiner Wiest, Hellerbrand Claus, Groszmann Roberto

المصدر: Journal of Hepatology. 36:175

مصطلحات موضوعية: medicine.medical_specialty, Hepatology, Nadolol, business.industry, Internal medicine, Portal venous pressure, medicine, Cardiology, Portal vein, Octreotide, business, Surgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5047e5c697c08ab3fc4977b2b36e576b
https://doi.org/10.1016/s0168-8278(02)80620-1