المؤلفون: Michael P. Menden, Francesco Paolo Casale, Johannes Stephan, Graham R. Bignell, Francesco Iorio, Ultan McDermott, Mathew J. Garnett, Julio Saez-Rodriguez, Oliver Stegle

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/a5f22af9ae8a4bdfa6b0d4bf920d0315

المؤلفون: Jiqiu Cheng, Jonas Demeulemeester, David C. Wedge, Hans Kristian M. Vollan, Jason J. Pitt, Hege G. Russnes, Bina P. Pandey, Gro Nilsen, Silje Nord, Graham R. Bignell, Kevin P. White, Anne-Lise Børresen-Dale, Peter J. Campbell, Vessela N. Kristensen, Michael R. Stratton, Ole Christian Lingjærde, Yves Moreau, Peter Van Loo

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e28c2813abff4f109325d96bafff3976

المؤلفون: Jiqiu Cheng, Jonas Demeulemeester, David C. Wedge, Hans Kristian M. Vollan, Jason J. Pitt, Hege G. Russnes, Bina P. Pandey, Gro Nilsen, Silje Nord, Graham R. Bignell, Kevin P. White, Anne-Lise Børresen-Dale, Peter J. Campbell, Vessela N. Kristensen, Michael R. Stratton, Ole Christian Lingjærde, Yves Moreau, Peter Van Loo

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8456cf857ba94524809cf64333ad72c5

المؤلفون: Jiqiu Cheng, Jonas Demeulemeester, David C. Wedge, Hans Kristian M. Vollan, Jason J. Pitt, Hege G. Russnes, Bina P. Pandey, Gro Nilsen, Silje Nord, Graham R. Bignell, Kevin P. White, Anne-Lise Børresen-Dale, Peter J. Campbell, Vessela N. Kristensen, Michael R. Stratton, Ole Christian Lingjærde, Yves Moreau, Peter Van Loo

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/340c2accd0cc41b6a16ec2081ec57688

المؤلفون: David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2289d578fc1d7b63139101d1d03793e
https://doi.org/10.1158/0008-5472.22386599

المؤلفون: David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559c580e0196c98d38f7d71fd3dbe244
https://doi.org/10.1158/0008-5472.c.6501584.v1

المؤلفون: David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5116204936401f059ff3c5ad97d43255
https://doi.org/10.1158/0008-5472.22386602

المؤلفون: David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68821b146c652a6305f71cf1619161f8
https://doi.org/10.1158/0008-5472.22386593

المؤلفون: David J. Adams, Tim Hubbard, Lara S. Collier, Anton Berns, Maarten van Lohuizen, P. Andy Futreal, Michael R. Stratton, David A. Largaespada, Louise van der Weyden, Catherine H. Wilson, Markus Brosch, Alistair G. Rust, Adam Butler, Graham R. Bignell, Jos Jonkers, Lodewyk Wessels, Jeroen de Ridder, Anthony G. Uren, Jaap Kool, Jenny Mattison

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12eeac7fd9c5ef28de657d84bf098aa8
https://doi.org/10.1158/0008-5472.22386596.v1

المؤلفون: Julio Saez-Rodriguez, Graham R. Bignell, Euan A. Stronach, Beiyuan Fu, Angela Matchan, Fiona M. Behan, Emanuel Gonçalves, Ruby Banerjee, Elisabeth Chen, Ultan McDermott, Gabriele Picco, Fengtang Yang, Kosuke Yusa, Luz Garcia Alonso, Cyril H. Benes, David J. Dow, Adam Butler, Elizabeth Anderson, Francesco Iorio, Mathew J. Garnett

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, BRD4, CRISPR-Cas systems, Carcinogenesis, Science, General Physics and Astronomy, Datasets as Topic, Antineoplastic Agents, 02 engineering and technology, Computational biology, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Fusion gene, 03 medical and health sciences, Targeted therapies, Cell Line, Tumor, Neoplasms, ROS1, medicine, Biomarkers, Tumor, Cancer genomics, CRISPR, Humans, lcsh:Science, Gene, Early Detection of Cancer, Regulation of gene expression, Multidisciplinary, Sequence Analysis, RNA, Gene Expression Profiling, Cancer, High-Throughput Nucleotide Sequencing, Functional genomics, General Chemistry, Genomics, 021001 nanoscience & nanotechnology, medicine.disease, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer cell, lcsh:Q, Gene Fusion, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e59227420fb1fc4592cbf1bb8cb97b3
https://doaj.org/article/faee146ac94c4c129948d57be9f339e0

المؤلفون: Scott Newman, Karen D Howarth, Chris D Greenman, Graham R Bignell, Simon Tavaré, Paul A W Edwards

المصدر: PLoS ONE, Vol 8, Iss 6, p e64991 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23762276/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b8a9b8d7fde040cb8298a7c71a5609f6

المؤلفون: Yuan Lu, Sarra L Ryan, David J Elliott, Graham R Bignell, P Andrew Futreal, David W Ellison, Simon Bailey, Steven C Clifford

المصدر: PLoS ONE, Vol 4, Iss 7, p e6159 (2009)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC2702821?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/b41022fe00cc4ec689320bfc476e8694

الاتاحة: https://doi.org/10.1371/journal.pone.0006159
https://doaj.org/article/b41022fe00cc4ec689320bfc476e8694

المؤلفون: Patricia Jaaks, Julio Saez-Rodriguez, Luz Garcia-Alonso, Cyril H. Benes, Nuno A. Fonseca, Graham R. Bignell, Simon S. McDade, Angela Matchan, Fiammetta Falcone, Ian Dunham, Gareth Peat, Miguel Pignatelli, Mathew J. Garnett, Francesco Iorio

المصدر: Garcia-Alonso, L M, Iorio, F, Matchan, A, Fonseca, N A, Jaaks, P, Peat, G, Pignatelli, M, Falcone, F, Benes, C H, Dunham, I, Bignell, G R, McDade, S, Garnett, M J & Saez-Rodriguez, J 2017, ' Transcription factor activities enhance markers of drug sensitivity in cancer ', Cancer Research, vol. 78, no. 3, pp. 1-35 . https://doi.org/10.1158/0008-5472.CAN-17-1679

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antineoplastic Agents, Apoptosis, Computational biology, Biology, Article, Small Molecule Libraries, Small hairpin RNA, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Neoplasms, Gene expression, Journal Article, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Humans, Transcription factor, Cell Proliferation, Regulation of gene expression, Cell growth, Cancer, medicine.disease, 3. Good health, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Oncology, Pharmacogenetics, Pharmacogenomics, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b960c74dc85d0a4f09aba6befe12d715
https://doi.org/10.1158/0008-5472.can-17-1679

المؤلفون: Nitzan Rosenfeld, James A. Morris, Christopher G. Smith, Gemma Young, Ferdia A. Gallagher, Emily Barker, Katrin Heider, Jonathan C. M. Wan, Ultan McDermott, Pui Ying Chan, Dineika Chandrananda, Eyal Fisher, Amer Durrani, Christine Parkinson, Constantine Alifrangis, Irena Hudecova, Graham R. Bignell, Charles E. Massie, Francesco Marass, Andrew B. Gill, Pippa Corrie, Florent Mouliere, Wendy N. Cooper, Davina Gale, Suzanne Murphy, Andrea Marshall, Mark R. Middleton

مصطلحات موضوعية: 0303 health sciences, Massive parallel sequencing, Sequencing data, Computational biology, Patient specific, Biology, Deep sequencing, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, In patient, Sensitivity (control systems), Genotyping, 030304 developmental biology, Advanced melanoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e2a1c4494cd1fa01a45b5766170bb3

المؤلفون: Helen Davies, Graham R Bignell, Charles Cox, Philip Stephens, Sarah Edkins, Sheila Clegg, Jon Teague, Hayley Woffendin, Mathew J Garnett, William Bottomley, Neil Davis, Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry A Gusterson, Colin Cooper, Janet Shipley, Darren Hargrave, Katherine Pritchard-Jones, Norman Maitland, Georgia Chenevix-Trench, Gregory J Riggins, Darell D Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne Flanagan, Andrew Nicholson, Judy W C Ho, Suet Y Leung, Siu T Yuen, Barbara L Weber, Hilliard F Seigler, Timothy L Darrow, Hugh Paterson, Richard Marais, Christopher J Marshall, Richard Wooster, Michael R Stratton, amp, P Andrew Futreal

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://eprints.gla.ac.uk/121/1/Davis,H_2002_pdf.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1046.6166; http://eprints.gla.ac.uk/121/1/Davis,H_2002_pdf.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1046.6166
http://eprints.gla.ac.uk/121/1/Davis,H_2002_pdf.pdf

المؤلفون: Anne Lise Børresen-Dale, Vessela N. Kristensen, Bina P. Pandey, Hans Kristian Moen Vollan, Jonas Demeulemeester, Peter J. Campbell, David C. Wedge, Graham R. Bignell, Michael R. Stratton, Yves Moreau, Silje Nord, Gro Nilsen, Jason J. Pitt, Kevin P. White, Ole Christian Lingjærde, Hege G. Russnes, Jiqiu Cheng, Peter Van Loo

المصدر: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Science, TEMPUS, MEDLINE, General Physics and Astronomy, 02 engineering and technology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Internal medicine, medicine, lcsh:Science, Author Correction, 030304 developmental biology, 0303 health sciences, Multidisciplinary, White (horse), Pan cancer, business.industry, Published Erratum, General Chemistry, 021001 nanoscience & nanotechnology, lcsh:Q, 0210 nano-technology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5944796b3699480231bac4e32b3c61d
http://europepmc.org/articles/PMC6297227

المؤلفون: Graham R. Bignell, Hans G. Drexler, Manuel Montesinos-Rongen, Andrea Haake, Reiner Siebert, Matthias Schlesner, Ludmil B. Alexandrov, Julia Richter, Ultan McDermott, Rabea Wagener

المصدر: Leukemia. 29:1612-1615

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Lymphoma, B-Cell, viruses, Biology, Minor Histocompatibility Antigens, Pathogenesis, immune system diseases, Cytidine Deaminase, Lymphoma, Primary Effusion, hemic and lymphatic diseases, Internal medicine, Tumor Cells, Cultured, medicine, Humans, Exome, ddc:610, B-cell lymphoma, Exome sequencing, Hematology, biochemical phenomena, metabolism, and nutrition, medicine.disease, Lymphoma, Leukemia, Oncology, Mutation, Immunology, Cancer research, Primary effusion lymphoma, Stem cell

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e793d797a1de8017a7ccab6df59eb83b
https://doi.org/10.1038/leu.2015.22

المؤلفون: Anneliese O. Speak, Marcela Sjoberg, van Dongen S, Nicholas K. Hayward, Jyoti S. Choudhary, Clara Alsinet, Graham R. Bignell, Kim Wong, Antonia L. Pritchard, Theodoros I. Roumeliotis, Mamunur Rashid, David J. Adams, David Tamborero, Velasco-Herrera Mdc, Nicola A. Thompson, Julia Newton-Bishop, Fiona M. Behan, Sofia Y. Chen, Emmanuelle Supper, Kosuke Yusa, Ultan McDermott, Chi C. Wong, L. Wessels, Anton J. Enright, Aida Shahrabi, Nanne Aben, Oscar Krijgsman, Marco Ranzani, Daniel S. Peeper, Magali Michaut, Kristel Kemper, Grinkevich, Ken Dutton-Regester, Mathew J. Garnett, Jérémie Nsengimana, Iyer, Francesco Iorio, Gemma Turner

مصطلحات موضوعية: MAPK/ERK pathway, Trametinib, Neuroblastoma RAS viral oncogene homolog, 0303 health sciences, medicine.drug_class, Melanoma, MEK inhibitor, Wild type, Pharmacology, Biology, medicine.disease, Tyrosine-kinase inhibitor, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Nilotinib, 030220 oncology & carcinogenesis, medicine, Cancer research, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f96e636071c9cde8ad0883e2073c4d
https://doi.org/10.1101/195354

المؤلفون: Fiammetta Falcone, Luz Garcia-Alonso, Simon S. McDade, Patricia Jaaks, Francesco Iorio, Julio Saez-Rodriguez, Mathew J. Garnett, Angela Matchan, Nuno A. Fonseca, Graham R. Bignell

مصطلحات موضوعية: 0303 health sciences, Cell, Cancer, Computational biology, Biology, Bioinformatics, medicine.disease, Resistant cell, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pharmacogenomics, Gene expression, Drug response, medicine, Gene, Transcription factor, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f828187ede191df4a09d10d6e73492
https://doi.org/10.1101/129478

المؤلفون: Fiona M. Behan, Julio Saez-Rodriguez, Francesco Iorio, Luz Garcia-Alonso, Graham R. Bignell, Mathew J. Garnett, Angela Matchan, Euan A. Stronach, Elisabeth Chen, Gabriele Picco

المصدر: ESMO Open. 3:A15-A16

مصطلحات موضوعية: Cancer Research, Cas9, Cancer, Computational biology, Biology, medicine.disease, Fusion gene, Oncology, Essential gene, Gene expression, medicine, CRISPR, Copy-number variation, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::966c1959e44b00260ece840b29024016
https://doi.org/10.1136/esmoopen-2018-eacr25.34