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1Academic Journal
المؤلفون: Robert Kleemann, Lars Verschuren, Marjan J Van Erk, Yuri Nikolsky, Nicole Hp Cnubben, Elwin R Verheij, Age K Smilde, Henk Fj Hendriks, Susanne Zadelaar, Graham J Smith, Valery Kaznacheev, Tatiana Nikolskaya, Anton Melnikov, Eva Hurt, Teake Kooistra
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/37/f5/Genome_Biol_2007_Sep_24_8(9)_R200.tar.gz
وصف الملف: application/zip
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2
المؤلفون: Graham J. Smith, Taryne Chong, Lisa Federico, Mark Naples, R Cheung, Khosrow Adeli, Denise Taylor
المصدر: Atherosclerosis. 185:21-31
مصطلحات موضوعية: Male, medicine.medical_specialty, Very low-density lipoprotein, Apolipoprotein B, Hamster, Insulin resistance, Cricetinae, Internal medicine, medicine, Animals, Rosuvastatin, Rosuvastatin Calcium, Cells, Cultured, Apolipoproteins B, Dyslipidemias, Metabolic Syndrome, Sulfonamides, Dose-Response Relationship, Drug, Mesocricetus, biology, nutritional and metabolic diseases, medicine.disease, Fluorobenzenes, Disease Models, Animal, Pyrimidines, Endocrinology, Liver, HMG-CoA reductase, Chromatography, Gel, Hepatocytes, biology.protein, Electrophoresis, Polyacrylamide Gel, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, Insulin Resistance, Cardiology and Cardiovascular Medicine, Dyslipidemia, medicine.drug, Lipoprotein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c9889bb039f4cee646f4589cf67b45
https://doi.org/10.1016/j .atherosclerosis.2005.05.010 -
3
المؤلفون: Geoffry Holdgate, Robert G. Davidson, Dennis W. Schneck, Linda K. Buckett, Graham J. Smith, Michael J Warwick, Fergus McTaggart, Alex McCormick
المصدر: The American Journal of Cardiology. 87:28-32
مصطلحات موضوعية: medicine.medical_specialty, Statin, biology, business.industry, medicine.drug_class, Cholesterol, nutritional and metabolic diseases, Pharmacology, Reductase, Rosuvastatin Calcium, chemistry.chemical_compound, chemistry, Oral administration, Enzyme inhibitor, Internal medicine, biology.protein, Cardiology, Medicine, Rosuvastatin, Cardiology and Cardiovascular Medicine, business, Pravastatin, medicine.drug
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4
المؤلفون: David S. Clarke, David Waterson, Donald J. Mirrlees, Steven C. Glossop, Alan J. Foubister, Robin Wood, Graham J. Smith, Brown George Robert, Stokes Elaine Sophie Elizabeth, David M. Hollinshead, Fergus McTaggart
المصدر: Journal of Medicinal Chemistry. 43:4964-4972
مصطلحات موضوعية: Pyridines, Stereochemistry, Administration, Oral, In Vitro Techniques, Chemical synthesis, Cyclase, Piperazines, 2,3-Oxidosqualene, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Biosynthesis, Microsomes, Drug Discovery, medicine, Animals, Enzyme Inhibitors, Intramolecular Transferases, Chromatography, High Pressure Liquid, chemistry.chemical_classification, biology, Anticholesteremic Agents, Rats, Cholesterol, Pyrimidines, Enzyme, chemistry, Simvastatin, Enzyme inhibitor, biology.protein, Molecular Medicine, Female, Lanosterol synthase, medicine.drug
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5
المؤلفون: R. P. Walker, Alan J. Foubister, Brown George Robert, Graham J. Smith, Susan Freeman, M. A. Eakin, Harrison Peter John, D. Griffiths, M. J. Taylor, P. R. O. Whittamore, Fergus McTaggart, A. C. Reid, Keith Blakeney Mallion, M. C. Johnson, R. J. Butlin, S. Chapman
المصدر: ChemInform. 27
مصطلحات موضوعية: Squalene, chemistry.chemical_compound, ATP synthase, biology, Chemistry, Stereochemistry, biology.protein, Organic chemistry, General Medicine
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6
المؤلفون: Fergus McTaggart, Alan J. Foubister, M. J. Taylor, David S. Clarke, John McCormick, Graham J. Smith, M. C. Johnson, Susan Freeman, Keith Blakeney Mallion, Harrison Peter John, Alan C. Reid, George R. Brown
المصدر: ChemInform. 27
مصطلحات موضوعية: chemistry.chemical_compound, Squalene, In vivo, Chemistry, Stereochemistry, Lipophilicity, Microsome, Substituent, Potency, General Medicine, IC50, Quinuclidine
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7
المؤلفون: Alan J. Foubister, Brown George Robert, D. A. Thomason, A. C. Reid, Graham J. Smith, Susan Freeman, P. R. O. Whittamore, Fergus McTaggart, D. J. Mirrlees, M. J. Taylor
المصدر: ChemInform. 28
مصطلحات موضوعية: chemistry.chemical_compound, Squalene, chemistry, ATP synthase, biology, Stereochemistry, biology.protein, Organic chemistry, General Medicine, Quinuclidine
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8
المصدر: ChemInform. 28
مصطلحات موضوعية: Chemistry, Stereochemistry, medicine, General Medicine, Sibutramine, medicine.drug
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9
المؤلفون: Steven Wang, Susan Birtles, Graham J. Smith, Linda K. Buckett, Paul D. Kemmitt, Alan Martin Birch, Tim J.D. Smith, Andrew V. Turnbull
المصدر: Journal of medicinal chemistry. 52(6)
مصطلحات موضوعية: Male, medicine.medical_specialty, Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Adipose tissue, Administration, Oral, Mice, Pharmacokinetics, Oral administration, In vivo, Internal medicine, Drug Discovery, Oxazines, medicine, Potency, Animals, Humans, Diacylglycerol O-Acyltransferase, Obesity, Enzyme Inhibitors, Rats, Wistar, chemistry.chemical_classification, Chemistry, Body Weight, Biological activity, medicine.disease, Rats, Mice, Inbred C57BL, Enzyme, Endocrinology, Pyrimidines, Molecular Medicine, Female, Metabolic syndrome
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10
المؤلفون: Marjan van Erk, A. I. Melnikov, Eva Hurt-Camejo, Ben van Ommen, Age K. Smilde, Yuri Nikolsky, Nicole H.P. Cnubben, Jan van der Greef, Robert Kleemann, Valery Kaznacheev, Teake Kooistra, Elwin Verheij, Graham J. Smith, H.F.J. Hendriks, Tatiana Nikolskaya, Lars Verschuren, Susanne Zadelaar
المساهمون: TNO Kwaliteit van Leven
المصدر: Genome Biology
Genome Biology, 9, 8مصطلحات موضوعية: Apolipoprotein E, Very low-density lipoprotein, Transcription, Genetic, protein p53, cholesterol blood level, cholesterol diet, Cholesterol, Dietary, chemistry.chemical_compound, stress, transcriptomics, Mice, aspartate aminotransferase, transcription factor FKHR, lipid metabolism, retinoid X receptor, hepatitis, animal, pathophysiology, peroxisome proliferator activated receptor alpha, transcription factor YY1, hydroxymethylglutaryl coenzyme A reductase, tumor necrosis factor alpha, hypercholesterolemia, Systems Biology, Mus, article, endothelial leukocyte adhesion molecule 1, gene control, gene expression regulation, metabolomics, retinoid X receptor alpha, very low density lipoprotein, immunoglobulin enhancer binding protein, female, Liver, high density lipoprotein, diet supplementation, lipids (amino acids, peptides, and proteins), gamma interferon, medicine.symptom, triacylglycerol, transcription regulation, medicine.medical_specialty, alanine aminotransferase, animal experiment, STAT5 protein, Inflammation, Biology, interleukin 1, Models, Biological, animal tissue, STAT3 protein, Internal medicine, STAT1 protein, medicine, Metabolome, Animals, Biomedical research, controlled study, Serum amyloid A, Liver X receptor, Analytical research, mouse, Smad3 protein, cholesterol intake, nonhuman, Cholesterol, Research, animal model, disease model, genetic transcription, cholesterol, Lipid metabolism, serum amyloid A, transcription factor Sp1, triacylglycerol blood level, biological model, Atherosclerosis, Diet, Disease Models, Animal, Endocrinology, Metabolism, chemistry, sterol regulatory element binding protein 1, protein blood level, sterol regulatory element binding protein 2, pathology, low density lipoprotein, aspartate aminotransferase blood level, alanine aminotransferase blood level, upregulation, platelet derived growth factor
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المؤلفون: Donald J. Mirrlees, Alan J. Foubister, David S. Clarke, Fergus McTaggart, Robin Wood, M. A. Eakin, M. C. Johnson, Brown George Robert, D. Griffiths, Graham J. Smith, Steven C. Glossop, Stokes Elaine Sophie Elizabeth, David M. Hollinshead
المصدر: Journal of medicinal chemistry. 42(7)
مصطلحات موضوعية: Male, Quinuclidines, Stereochemistry, Administration, Oral, In Vitro Techniques, Cyclase, 2,3-Oxidosqualene, chemistry.chemical_compound, Squalene, Structure-Activity Relationship, Biosynthesis, Microsomes, Drug Discovery, Animals, Humans, Enzyme Inhibitors, IC50, Intramolecular Transferases, Chromatography, High Pressure Liquid, biology, Anticholesteremic Agents, Callithrix, Lipid Metabolism, Lipids, Rats, chemistry, Biochemistry, Liver, Enzyme inhibitor, biology.protein, Molecular Medicine, Quinuclidine, Lanosterol synthase
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12
المؤلفون: David S. Clarke, John McCormick, Alan C. Reid, M. C. Johnson, Alan J. Foubister, George R. Brown, Fergus McTaggart, Graham J. Smith, Susan Freeman, Harrison Peter John, M. J. Taylor, Keith Blakeney Mallion
المصدر: Journal of medicinal chemistry. 39(15)
مصطلحات موضوعية: Quinuclidines, Stereochemistry, Substituent, Mevalonic Acid, Chemical synthesis, chemistry.chemical_compound, Squalene, Structure-Activity Relationship, Drug Discovery, Potency, Animals, Enzyme Inhibitors, Farnesyl-diphosphate farnesyltransferase, Binding Sites, biology, Molecular Structure, Anticholesteremic Agents, Stereoisomerism, Rats, Cholesterol, Farnesyl-Diphosphate Farnesyltransferase, chemistry, Enzyme inhibitor, Lipophilicity, biology.protein, Microsomes, Liver, Molecular Medicine, Quinuclidine
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13
المؤلفون: Fergus McTaggart, Graham J. Smith, Robert G. Davidson, Susan Freeman, Keith Blakeney Mallion, Walter H.J. Ward, Geoffrey A. Holdgate, Donald J. Mirrlees, Brown George Robert
المصدر: Biochemical pharmacology. 51(11)
مصطلحات موضوعية: Quinuclidines, Stereochemistry, Farnesyl pyrophosphate, Mevalonic Acid, Tritium, Biochemistry, Sensitivity and Specificity, chemistry.chemical_compound, Squalene, Dolichol, Animals, Enzyme Inhibitors, Pharmacology, Farnesyl-diphosphate farnesyltransferase, biology, Cholesterol, Rats, Inbred Strains, Farnesol, Rats, Kinetics, Farnesyl-Diphosphate Farnesyltransferase, chemistry, Liver, Enzyme inhibitor, biology.protein, Female, Mevalonate pathway
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14353 Effect of statins on protein uptake and cholesterol biosynthesis in kidney proximal tubule cells
المؤلفون: James E. Sidaway, Terry C. Orton, Graham J. Smith, Robert G. Davidson, Nigel J. Brunskill, Fergus McTaggart, Robert C. Scott
المصدر: Toxicology Letters. 144:s96
مصطلحات موضوعية: medicine.medical_specialty, Kidney, Endocrinology, medicine.anatomical_structure, Protein uptake, Chemistry, Internal medicine, medicine, Proximal tubule, General Medicine, Toxicology, Cholesterol biosynthesis
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15
المصدر: Journal of the Chemical Society, Perkin Transactions 1. :2583
مصطلحات موضوعية: Chemistry, Stereochemistry, medicine, Organic chemistry, Sibutramine, medicine.drug
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16Academic Journal
المؤلفون: Alan M. Birch, Susan Birtles, Linda K. Buckett, Paul D. Kemmitt, Graham J. Smith, Tim J. D. Smith, Andrew V. Turnbull, Steven J. Y. Wang
المصدر: Journal of Medicinal Chemistry; Mar2009, Vol. 52 Issue 6, p1558-1568, 11p
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17
المؤلفون: G.R. Brown, K.B. Mallion, Robert G. Davidson, Graham J. Smith, C. Dunkley, Fergus McTaggart
المصدر: Atherosclerosis. 109:252
مصطلحات موضوعية: Squalene, chemistry.chemical_compound, ATP synthase, biology, Biochemistry, Chemistry, Hepatic cholesterol, biology.protein, Cardiology and Cardiovascular Medicine