المؤلفون: Baker, A-M, Nageswaran, G, Nenclares, P, Ronel, T, Smith, K, Kimberley, C, Laclé, MM, Bhide, S, Harrington, KJ, Melcher, A, Rodriguez-Justo, M, Chain, B, Graham, TA

المساهمون: Baker, Ann-Marie Clare, Nenclares, Pablo, Ronel, Tahel, Harrington, Kevin, Melcher, Alan, Graham, Trevor

وصف الملف: application/pdf

Relation: Cancer Research; https://repository.icr.ac.uk/handle/internal/6194

الاتاحة: https://repository.icr.ac.uk/handle/internal/6194

المؤلفون: Cornish, AJ, Gruber, AJ, Kinnersley, B, Chubb, D, Frangou, A, Caravagna, G, Noyvert, B, Lakatos, E, Wood, HM, Thorn, S, Culliford, R, Arnedo-Pac, C, Househam, J, Cross, W, Sud, A, Law, P, Leathlobhair, MN, Hawari, A, Woolley, C, Sherwood, K, Feeley, N, Gül, G, Fernandez-Tajes, J, Zapata, L, Alexandrov, LB, Murugaesu, N, Sosinsky, A, Mitchell, J, Lopez-Bigas, N, Quirke, P, Church, DN, Tomlinson, IPM, Sottoriva, A, Graham, TA, Wedge, DC, Houlston, RS

المساهمون: Cornish, Alexander, Kinnersley, Benjamin, Culliford, Richard, Househam, Jacob, Sud, Amit, Law, Philip, Sottoriva, Andrea, Graham, Trevor, Houlston, Richard

وصف الملف: application/pdf

Relation: Nature, 2024; https://repository.icr.ac.uk/handle/internal/6341

الاتاحة: https://repository.icr.ac.uk/handle/internal/6341

المؤلفون: Chen, B, Ramazzotti, D, Heide, T, Spiteri, I, Fernandez-Mateos, J, James, C, Magnani, L, Graham, TA, Sottoriva, A

المساهمون: Chen, B, Ramazzotti, D, Heide, T, Spiteri, I, Fernandez-Mateos, J, James, C, Magnani, L, Graham, T, Sottoriva, A

مصطلحات موضوعية: Colorectal cancer, Mutational signature, Tumorigenesis

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/38030613; info:eu-repo/semantics/altIdentifier/wos/WOS:001111154200017; volume:14; issue:1; journal:NATURE COMMUNICATIONS; https://hdl.handle.net/10281/452178; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85178170872

الاتاحة: https://hdl.handle.net/10281/452178
https://doi.org/10.1038/s41467-023-43329-5

المؤلفون: Haughey, MJ, Bassolas, A, Sousa, S, Baker, A-M, Graham, TA, Nicosia, V, Huang, W

Relation: PLoS Comput. Biol.; Haughey MJ, Bassolas A, Sousa S, Baker A-M, Graham TA, Nicosia V, et al. (2023) First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer. PLoS Comput Biol 19(3): e1010952. https://doi.org/10.1371/journal.pcbi.1010952; https://qmro.qmul.ac.uk/xmlui/handle/123456789/96999

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96999

المؤلفون: Zapata, L, Caravagna, G, Williams, MJ, Lakatos, E, AbdulJabbar, K, Werner, B, Chowell, D, James, C, Gourmet, L, Milite, S, Acar, A, Riaz, N, Chan, TA, Graham, TA, Sottoriva, A

المساهمون: Zapata Ortiz, Luis, Graham, Trevor, Sottoriva, Andrea

مصطلحات موضوعية: Humans, Neoplasms, Nivolumab, Antigens, Neoplasm, CD8-Positive T-Lymphocytes, Mutation

جغرافية الموضوع: United States

وصف الملف: Print-Electronic; 460; application/pdf

Relation: Nature Genetics, 2023, 55 (3), pp. 451 - 460; https://repository.icr.ac.uk/handle/internal/5761

الاتاحة: https://doi.org/10.1038/s41588-023-01313-1
https://repository.icr.ac.uk/handle/internal/5761

المؤلفون: Ingles Garces, AH, Porta, N, Graham, TA, Banerji, U

المساهمون: Porta, Nuria, Graham, Trevor, Banerji, Udai

مصطلحات موضوعية: Cancer evolution, Clinical trials, Drug resistance, Humans, Clinical Trials as Topic, Neoplasms, Clonal Evolution

جغرافية الموضوع: Netherlands

وصف الملف: Print-Electronic; application/pdf

Relation: ARTN 102583; S0305-7372(23)00075-0; Cancer Treatment Reviews, 2023, 118 pp. 102583 -; https://repository.icr.ac.uk/handle/internal/5947

الاتاحة: https://repository.icr.ac.uk/handle/internal/5947
https://doi.org/10.1016/j.ctrv.2023.102583

المؤلفون: Gatenbee, CD, Baker, AM, Schenck, RO, Strobl, M, West, J, Neves, MP, Hasan, SY, Lakatos, E, Martinez, P, Cross, WCH, Jansen, M, Rodriguez-Justo, M, Whelan, CJ, Sottoriva, A, Leedham, S, Robertson-Tessi, M, Graham, TA, Anderson, ARA

المصدر: Nature Communications , 13 , Article 1798. (2022)

مصطلحات موضوعية: Applied mathematics, Colorectal cancer, Tumour immunology

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10147022/1/s41467-022-29027-8.pdf; https://discovery.ucl.ac.uk/id/eprint/10147022/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10147022/1/s41467-022-29027-8.pdf
https://discovery.ucl.ac.uk/id/eprint/10147022/

المؤلفون: Gabbutt, C, Schenck, RO, Weisenberger, DJ, Kimberley, C, Berner, A, Househam, J, Lakatos, E, Robertson-Tessi, M, Martin, I, Patel, R, Clark, SK, Latchford, A, Barnes, CP, Leedham, SJ, Anderson, ARA, Graham, TA, Shibata, D

المصدر: Nature Biotechnology (2022) (In press).

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biotechnology & Applied Microbiology, MITOCHONDRIAL-DNA MUTATIONS, STEM-CELL, HUMAN COLON, INTESTINAL EPITHELIUM, FIELD CANCERIZATION, CLONAL ARCHITECTURE, SOMATIC MUTATIONS, GENE-EXPRESSION, CRYPT, REVEALS

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10141745/1/Barnes_Fluctuating%20methylation%20clocks%20for%20cell%20lineage%20tracing%20at%20high%20temporal%20resolution%20in%20human%20tissues_AOP.pdf; https://discovery.ucl.ac.uk/id/eprint/10141745/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10141745/1/Barnes_Fluctuating%20methylation%20clocks%20for%20cell%20lineage%20tracing%20at%20high%20temporal%20resolution%20in%20human%20tissues_AOP.pdf
https://discovery.ucl.ac.uk/id/eprint/10141745/

المؤلفون: Househam, J, Heide, T, Cresswell, GD, Spiteri, I, Kimberley, C, Zapata, L, Lynn, C, James, C, Mossner, M, Fernandez-Mateos, J, Vinceti, A, Baker, A-M, Gabbutt, C, Berner, A, Schmidt, M, Chen, B, Lakatos, E, Gunasri, V, Nichol, D, Costa, H, Mitchinson, M, Ramazzotti, D, Werner, B, Iorio, F, Jansen, M, Caravagna, G, Barnes, CP, Shibata, D, Bridgewater, J, Rodriguez-Justo, M, Magnani, L, Sottoriva, A, Graham, TA

وصف الملف: 744 - +

Relation: NATURE; https://qmro.qmul.ac.uk/xmlui/handle/123456789/83423

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/83423
https://doi.org/10.1038/s41586-022-05311-x

المؤلفون: Hoare, JI, Hockings, H, Saxena, J, Silva, VL, Haughey, MJ, Wood, GE, Nicolini, F, Mirza, H, McNeish, IA, Huang, W, Maniati, E, Graham, TA, Lockley, M

مصطلحات موضوعية: High grade serous ovarian cancer, Drug resistance, Platinum, Chemotherapy, Evolution, Transcription, Gene expression, Extracellular matrix, Non-genetic

وصف الملف: 96 - 106

Relation: GYNECOLOGIC ONCOLOGY; https://qmro.qmul.ac.uk/xmlui/handle/123456789/80403

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/80403
https://doi.org/10.1016/j.ygyno.2022.07.027

المؤلفون: Demircioglu, F, Wang, J, Candido, J, Costa, ASH, Casado, P, de Luxan Delgado, B, Reynolds, LE, Gomez-Escudero, J, Newport, E, Rajeeve, V, Baker, A-M, Roy-Luzarraga, M, Graham, TA, Foster, J, Wang, Y, Campbell, JJ, Singh, R, Zhang, P, Schall, TJ, Balkwill, FR, Sosabowski, J, Cutillas, PR, Frezza, C, Sancho, P, Hodivala-Dilke, K

المساهمون: Baker, Ann-Marie Clare, Graham, Trevor

مصطلحات موضوعية: Animals, Breast Neoplasms, Cancer-Associated Fibroblasts, Cell Line, Tumor, Cell Proliferation, Chemokines, Female, Focal Adhesion Protein-Tyrosine Kinases, Glycolysis, Humans, Male, Metabolic Networks and Pathways, Mice, Inbred C57BL, Neoplasms, Pancreatic Neoplasms, Phosphoproteins, Stromal Cells, Survival Analysis, Xenograft Model Antitumor Assays

جغرافية الموضوع: England

وصف الملف: Electronic; application/pdf

Relation: 1290; Nature Communications, 2020, 11 (1), pp. 1290 -; https://repository.icr.ac.uk/handle/internal/5451

الاتاحة: https://doi.org/10.1038/s41467-020-15104-3
https://repository.icr.ac.uk/handle/internal/5451

المؤلفون: Baker, A-M, Gabbutt, C, Williams, MJ, Cereser, B, Jawad, N, Rodriguez-Justo, M, Jansen, M, Barnes, CP, Simons, BD, McDonald, SA, Graham, TA, Wright, NA

المساهمون: Baker, Ann-Marie Clare, Gabbutt, Calum, Graham, Trevor

مصطلحات موضوعية: colon crypt, crypt fission, crypt fusion, evolutionary dynamics, lineage tracing, mathematical modelling, Aberrant Crypt Foci, Adult, Aged, Cell Culture Techniques, Cell Fusion, Colon, Electron Transport Complex IV, Female, Homeostasis, Humans, Intestinal Mucosa, Male, Middle Aged, Models, Theoretical

جغرافية الموضوع: England

وصف الملف: Print-Electronic; 1993; application/pdf

Relation: gutjnl-2018-317540; Gut, 2019, 68 (11), pp. 1986 - 1993; https://repository.icr.ac.uk/handle/internal/5376

الاتاحة: https://repository.icr.ac.uk/handle/internal/5376
https://doi.org/10.1136/gutjnl-2018-317540

المؤلفون: Heide, T, Househam, J, Cresswell, GD, Spiteri, I, Lynn, C, Mossner, M, Kimberley, C, Fernandez-Mateos, J, Chen, B, Zapata, L, James, C, Barozzi, I, Chkhaidze, K, Nichol, D, Gunasri, V, Berner, A, Schmidt, M, Lakatos, E, Baker, A-M, Costa, H, Mitchinson, M, Piazza, R, Jansen, M, Caravagna, G, Ramazzotti, D, Shibata, D, Bridgewater, J, Rodriguez-Justo, M, Magnani, L, Graham, TA, Sottoriva, A

المساهمون: Heide, Timon, Househam, Jacob, Zapata Ortiz, Luis, Baker, Ann-Marie Clare, Magnani, Luca, Graham, Trevor, Sottoriva, Andrea

جغرافية الموضوع: England

وصف الملف: Print-Electronic; application/pdf

Relation: Nature, 2022; https://repository.icr.ac.uk/handle/internal/5558

الاتاحة: https://doi.org/10.1038/s41586-022-05202-1
https://repository.icr.ac.uk/handle/internal/5558

المؤلفون: Sequeira, I, Rashid, M, Tomás, IM, Williams, MJ, Graham, TA, Adams, DJ, Vigilante, A, Watt, FM

المساهمون: Graham, Trevor

مصطلحات موضوعية: 4-Nitroquinoline-1-oxide, Animals, Cadherins, Carcinogenesis, Carcinoma, Squamous Cell, Disease Models, Animal, Disease Progression, Exome, Gene Expression Regulation, Neoplastic, Genes, Neoplasm, p53, Genomics, Mice, Inbred C57BL, Mouth Neoplasms, Mutation, Neoplasm Invasiveness, Receptor, Notch1

جغرافية الموضوع: England

وصف الملف: Electronic; application/pdf

Relation: ARTN 5671; Nature Communications, 2020, 11 (1), pp. 5671 -; https://repository.icr.ac.uk/handle/internal/5460

الاتاحة: https://doi.org/10.1038/s41467-020-19401-9
https://repository.icr.ac.uk/handle/internal/5460

المؤلفون: Guo, Q, Lakatos, E, Bakir, IA, Curtius, K, Graham, TA, Mustonen, V

المساهمون: Graham, Trevor

مصطلحات موضوعية: Formaldehyde, Genome, Human, Humans, Mutation, Paraffin Embedding, Tissue Fixation

جغرافية الموضوع: England

وصف الملف: Electronic; application/pdf

Relation: ARTN 4487; Nature Communications, 2022, 13 (1), pp. 4487 -; https://repository.icr.ac.uk/handle/internal/5607

الاتاحة: https://doi.org/10.1038/s41467-022-32041-5
https://repository.icr.ac.uk/handle/internal/5607

المؤلفون: Bollen, Y, Stelloo, E, van Leenen, P, van den Bos, M, Ponsioen, B, Lu, B, van Roosmalen, MJ, Bolhaqueiro, ACF, Kimberley, C, Mossner, M, Cross, WCH, Besselink, NJM, van der Roest, B, Boymans, S, Oost, KC, de Vries, SG, Rehmann, H, Cuppen, E, Lens, SMA, Kops, GJPL, Kloosterman, WP, Terstappen, LWMM, Barnes, CP, Sottoriva, A, Graham, TA, Snippert, HJG

المصدر: Nature Genetics (2021) (In press).

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10131067/1/s41588-021-00891-2.pdf; https://discovery.ucl.ac.uk/id/eprint/10131067/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10131067/1/s41588-021-00891-2.pdf
https://discovery.ucl.ac.uk/id/eprint/10131067/

المؤلفون: Curtius, K, Kabir, M, Al Bakir, I, Choi, CHR, Hartono, JL, Johnson, M, East, JE, Oxford IBD Cohort Study Investigators, Lindsay, JO, Vega, R, Thomas-Gibson, S, Warusavitarne, J, Wilson, A, Graham, TA, Hart, A

مصطلحات موضوعية: clinical decision making, colorectal cancer, dysplasia, ulcerative colitis

Relation: Gut; Curtius K, Kabir M, Al Bakir I, et al. Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool. Gut. Published Online First: 14 May 2021. doi:10.1136/gutjnl-2020-323546; https://qmro.qmul.ac.uk/xmlui/handle/123456789/73879

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/73879
https://doi.org/10.1136/gutjnl-2020-323546

المؤلفون: Yalchin, M, Baker, A-M, Graham, TA, Hart, A

مصطلحات موضوعية: cancer risk, inflammatory bowel disease, molecular biomarkers, molecular risk factors, risk factors

Relation: Cancers (Basel); Yalchin, M.; Baker, A.-M.; Graham, T.A.; Hart, A. Predicting Colorectal Cancer Occurrence in IBD. Cancers 2021, 13, 2908. https://doi.org/10.3390/cancers13122908; https://qmro.qmul.ac.uk/xmlui/handle/123456789/72990

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/72990
https://doi.org/10.3390/cancers13122908

المؤلفون: Lakatos, E, Hockings, H, Mossner, M, Huang, W, Lockley, M, Graham, TA

مصطلحات موضوعية: Cancer, Cancer systems biology, Genomics

وصف الملف: 102889 - ?

Relation: iScience; https://qmro.qmul.ac.uk/xmlui/handle/123456789/73822

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/73822
https://doi.org/10.1016/j.isci.2021.102889

المؤلفون: Williams, MJ, Zapata, L, Werner, B, Barnes, CP, Sottoriva, A, Graham, TA

المصدر: Elife , 9 , Article e48714. (2020)

مصطلحات موضوعية: Computational and systems biology, genetics and genomics, somatic evolution, cancer evolution, dn/ds, population genetics, distribution of fitness effects

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10094676/1/Barnes_Measuring%20the%20distribution%20of%20fitness%20effects%20in%20somatic%20evolution%20by%20combining%20clonal%20dynamics%20with%20dN%3AdS%20ratios_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10094676/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10094676/1/Barnes_Measuring%20the%20distribution%20of%20fitness%20effects%20in%20somatic%20evolution%20by%20combining%20clonal%20dynamics%20with%20dN%3AdS%20ratios_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10094676/