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1Academic Journal
المؤلفون: Nicholas Pervolarakis, Quy H. Nguyen, Justice Williams, Yanwen Gong, Guadalupe Gutierrez, Peng Sun, Darisha Jhutty, Grace X.Y. Zheng, Corey M. Nemec, Xing Dai, Kazuhide Watanabe, Kai Kessenbrock
المصدر: Cell Reports, Vol 33, Iss 3, Pp 108273- (2020)
مصطلحات موضوعية: mammary stem cells, single-cell genomics, transcriptomics, chromatin accessibility, cellular heterogeneity, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Jun Feng, Drake LeFace, Aaron Cooper, Michelle L.T. Nguyen, Suchismita Mohanty, Angela C. Boroughs, Jason F. Hall, Adam J. Litterman, Jenessa B. Smith, Jeff Granja, Dina Polyak, John D. Gagnon, Jaspar Williams, Kanika Chawla, Susie Jun, Stephen Santoro, Tarjei S. Mikkelsen, Grace X.Y. Zheng, Natalie Bezman, David DeTomaso
المصدر: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
مصطلحات موضوعية: Pharmacology, Cancer Research, Chemistry, Immunology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Integrated circuit, Molecular biology, law.invention, Oncology, law, Molecular Medicine, Immunology and Allergy, Potency, Car t cells, RC254-282
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المؤلفون: M. Ryan Corces, Ravindra Majeti, Arwa Kathiria, Howard Y. Chang, Eric Gars, William J. Greenleaf, Michaela Liedtke, Lisa M. McGinnis, Jeffrey M. Granja, Grace X.Y. Zheng, Benjamin Parks, Sandy Klemm, Anja Mezger
المصدر: Nature Biotechnology. 37:1458-1465
مصطلحات موضوعية: Regulation of gene expression, 0303 health sciences, Biomedical Engineering, Bioengineering, Computational biology, Biology, Applied Microbiology and Biotechnology, Phenotype, Chromatin, Transcriptome, Gene expression profiling, 03 medical and health sciences, 0302 clinical medicine, Regulatory sequence, Molecular Medicine, Epigenetics, Gene, 030217 neurology & neurosurgery, 030304 developmental biology, Biotechnology
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المؤلفون: Mohammed Al Aklabi, James M. Piret, Lori J. West, Megan K. Levings, Ivan M. Rebeyka, Sabine Ivison, Keli L. Hippen, Michael B. Hall, Katherine N. MacDonald, Sanjiv K. Gandhi, Darren H. Freed, Bruce R. Blazar, Romy E. Hoeppli, I. Esme Dijke, Grace X.Y. Zheng
المصدر: Cytotherapy
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Manufactured Materials, Time Factors, Regulatory T cell, Immunology, Cell, Cell Culture Techniques, Cell- and Tissue-Based Therapy, Thymus Gland, Biology, Lymphocyte Activation, T-Lymphocytes, Regulatory, Article, Cryopreservation, Cell therapy, Dynabeads, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Immunology and Allergy, Good manufacturing practice, Cells, Cultured, Genetics (clinical), Cell Proliferation, Transplantation, Tissue Engineering, Infant, Cell Biology, Systematic testing, Culture Media, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Oncology, Homogeneous, Child, Preschool, 030220 oncology & carcinogenesis
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المؤلفون: Grace X.Y. Zheng, Noemi Andor, Debra K. Czerwinski, Susan M. Grimes, Hanlee P. Ji, Erin F. Simonds, William A. Weiss, Jiamin Chen, Matthew Kubit, Stephanie Greer, Ronald Levy, Christina Wood-Bouwens
المصدر: Blood. 133:1119-1129
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, Lymphoma, B-Cell, Biopsy, T cell, Palatine Tonsil, Immunology, Follicular lymphoma, Biology, T-Lymphocytes, Regulatory, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Immune system, Tumor Microenvironment, medicine, Humans, Cell Lineage, Lectins, C-Type, Lymphoma, Follicular, B cell, Regulation of gene expression, Tumor microenvironment, Lymphoid Neoplasia, Gene Expression Regulation, Leukemic, Receptors, IgE, Sequence Analysis, RNA, Gene Expression Profiling, Histocompatibility Antigens Class II, Cell Biology, Hematology, Flow Cytometry, Hematopoietic Stem Cells, medicine.disease, Immune checkpoint, Gene expression profiling, 030104 developmental biology, medicine.anatomical_structure, CD52 Antigen, Immune System, Immunoglobulin G, 030220 oncology & carcinogenesis, CCAAT-Enhancer-Binding Proteins, Leukocytes, Mononuclear, Cancer research, Transcriptome, beta 2-Microglobulin
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المؤلفون: Grace X.Y. Zheng, Andreea Bratu, Hiwot Tafessu, Jacek A. Kopec, Ni Gusti Ayu Nanditha, Viviane D. Lima, Taylor McLinden, Robert S. Hogg, Julio S. G. Montaner
المصدر: Can J Public Health
مصطلحات موضوعية: medicine.medical_specialty, Population, Marginal structural model, HIV Infections, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, 030212 general & internal medicine, education, 030304 developmental biology, 0303 health sciences, education.field_of_study, British Columbia, business.industry, Mortality rate, Public health, Hazard ratio, Public Health, Environmental and Occupational Health, Multimorbidity, General Medicine, Confidence interval, Health equity, 3. Good health, Anti-Retroviral Agents, Cohort, Quantitative Research, business, Demography
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المؤلفون: Grace X.Y. Zheng, Somya Khare, Brendan Galvin, Robby Moot, Aaron Cooper, Michelle Nguyen, Michelle Tan, Shan Sabri, Audre May, Jun Fung, Anzhi Yao, Andrea Liu, Matt Drever, Steve Santoro, W Nicholas Haining, Tarjei Mikkelsen
المصدر: Cancer Research. 82:2840-2840
مصطلحات موضوعية: Cancer Research, Oncology
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المؤلفون: Pehr B. Harbury, Grace X.Y. Zheng, Solongo B. Ziraldo, Lisa E. Wagar, Tarjei S. Mikkelsen, Manuel R. Amieva, Jihang Ju, Calvin J. Kuo, Mar Margalef-Català, Jeffrey S. Glenn, Daniel J. Hart, Mark M. Davis, Arpit Batish, Caitlin E. Edwards, Ameen A. Salahudeen, Arjun Rustagi, Catherine A. Blish, Sean M. de la O, Shannon S. Choi, Monica Nagendran, Ralph S. Baric, Vincent C. Luca, Junjie Zhu, Tushar J. Desai, Khanh Nguyen, Jessica M. Terry, Tatsuya Usui, Phillip Belgrader, Ryan A. Flynn, Vincent van Unen, Chiara Sabatti, Benedict Anchang, K. Christopher Garcia, António J. M. Santos
المصدر: Nature
مصطلحات موضوعية: education.field_of_study, Lung, Transdifferentiation, Population, Biology, respiratory system, Article, Cell biology, respiratory tract diseases, Basal (phylogenetics), medicine.anatomical_structure, Single-cell analysis, Organoid, medicine, Stem cell, Progenitor cell, education
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المؤلفون: Arnold Han, Xiao Li, Solongo B. Ziraldo, Michael Snyder, Aaron J. W. Hsueh, Tarjei S. Mikkelsen, Kathryn A. Larkin, Vincent C. Luca, Julie Wilhelmy, Akifumi Ootani, Heather Ordonez, Luis A. Chia, Kelly Roelf, Mark Lee, Christopher R. Bolen, Junlei Chang, Hiroo Ueno, Calvin J. Kuo, Susan J. Henning, Paige S. Davies, Jessica M. Terry, Kelley S. Yan, Jenny Yuan, Phillip Belgrader, K. Christopher Garcia, Melissa H. Wong, Amanda T. Mah, Irving L. Weissman, Claudia Y. Janda, Grace X.Y. Zheng, Richard J. von Furstenberg
المصدر: Nature. 545:238-242
مصطلحات موضوعية: 0301 basic medicine, Genetics, Frizzled, Multidisciplinary, Beta-catenin, biology, Receptor expression, Wnt signaling pathway, LGR5, LRP6, LRP5, Hedgehog signaling pathway, Cell biology, 03 medical and health sciences, 030104 developmental biology, biology.protein
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المؤلفون: Kai Kessenbrock, Guadalupe Gutierrez, Nicholas Pervolarakis, Xing Dai, Grace X.Y. Zheng, Kazuhide Watanabe, Darisha Jhutty, Peng Sun, Corey M. Nemec, Quy H. Nguyen
مصطلحات موضوعية: Transcriptome, Cell type, medicine.anatomical_structure, Lineage (genetic), medicine, Progenitor cell, Biology, Gene, Epithelium, Chromatin, Cell biology, Progenitor
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المؤلفون: Michaela Liedtke, Benjamin Parks, Howard Y. Chang, Lisa M. McGinnis, Ravindra Majeti, Jeffrey M. Granja, Sandy Klemm, Grace X.Y. Zheng, Anja Mezger, William J. Greenleaf, Eric Gars, Arwa Kathiria
مصطلحات موضوعية: education.field_of_study, Acute leukemia, Myeloid, Population, Context (language use), Computational biology, Biology, medicine.disease, Leukemia, Haematopoiesis, medicine.anatomical_structure, medicine, Epigenetics, Bone marrow, education
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المؤلفون: William J. Greenleaf, Jean Wang, Darisha Jhutty, Grace X.Y. Zheng, Kathryn E. Yost, Yifeng Yin, Preyas Shah, Corey M. Nemec, Ansuman T. Satpathy, Li Wang, Francesca Meschi, M. Ryan Corces, Howard Y. Chang, Jason C. Bell, Jeffrey M. Granja, Geoffrey P. McDermott, Paul G. Giresi, Anne Lynn S. Chang, Yanyan Qi, Brett N. Olsen, Maxwell R. Mumbach, Sarah E. Pierce
المصدر: Nat Biotechnol
مصطلحات موضوعية: Cell type, T cell, Cellular differentiation, T-Lymphocytes, Cell, Biomedical Engineering, Bioengineering, Bone Marrow Cells, Biology, Applied Microbiology and Biotechnology, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, medicine, Humans, Computer Simulation, Progenitor cell, 030304 developmental biology, 0303 health sciences, Tumor microenvironment, Cell growth, High-Throughput Nucleotide Sequencing, Chromatin, Cell biology, Hematopoiesis, medicine.anatomical_structure, Gene Expression Regulation, Leukocytes, Mononuclear, Molecular Medicine, Single-Cell Analysis, 030217 neurology & neurosurgery, CD8, Biotechnology, Transcription Factors
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المؤلفون: Francisco M. De La Vega, Xingnan Li, William C. Hahn, Fan Zhao, Jesse S. Boehm, Brian C. Deutsch, Yuen-Yi Tseng, Grace X.Y. Zheng, Lillian Liao, Allison Zemek, Sahar Alkhairy, Ameen A. Salahudeen, Valeria Giangarra, John B. Sunwoo, Jihang Ju, Lincoln Nadauld, James T. Neal, Shin Heng Chiou, Paula Keskula, Coyin Oh, Daniel Mendoza-Villanueva, Amber R. Smith, Liora M. Schultz, Junjie Zhu, Chiara Sabatti, Thomas J. Metzner, Kasper Karlsson, John T. Leppert, Mark M. Davis, Calvin J. Kuo, Iris H. Liu, Pamela L. Kunz, Caitlin L. Grzeskowiak, Joseph C. Liao
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_treatment, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Biology, General Biochemistry, Genetics and Molecular Biology, B7-H1 Antigen, Article, 03 medical and health sciences, Mice, Immune system, medicine, Organoid, Tumor Microenvironment, Animals, Humans, Tumor microenvironment, Mice, Inbred BALB C, Tumor-infiltrating lymphocytes, Models, Immunological, Immunotherapy, Neoplasms, Experimental, medicine.disease, Primary tumor, Immune checkpoint, Coculture Techniques, Neoplasm Proteins, Organoids, 030104 developmental biology, Cancer research, Female
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المؤلفون: Mar Margalef-Català, Caitlin E. Edwards, Manuel R. Amieva, Jihang Ju, Lisa E. Wagar, Arjun Rustagi, Khanh Nguyen, Vincent C. Luca, Tatsuya Usui, Ameen A. Salahudeen, Tarjei S. Mikkelsen, Shannon S. Choi, Ralph S. Baric, António J. M. Santos, Jessica M. Terry, Grace X.Y. Zheng, Mark M. Davis, Catherine A. Blish, Ryan A. Flynn, Phillip Belgrader, Solongo B. Ziraldo, Vincent van Unen, Jeffrey S. Glenn, Junjie Zhu, Sean M. de la O, Monica Nagendran, Tushar J. Desai, Calvin J. Kuo, Arpit Batish, Benedict Anchang, K. Christopher Garcia, Daniel J. Hart, Pehr B. Harbury, Chiara Sabatti
المصدر: bioRxiv
Natureمصطلحات موضوعية: Pathology, medicine.medical_specialty, Cell division, Cellular differentiation, Population, Pneumonia, Viral, Biology, In Vitro Techniques, Integrin alpha6, Models, Biological, Article, Tissue Culture Techniques, Basal (phylogenetics), Influenza A Virus, H1N1 Subtype, medicine, Organoid, Humans, Progenitor cell, education, Lung, education.field_of_study, Multidisciplinary, SARS-CoV-2, Integrin beta4, Interstitial lung disease, COVID-19, Cell Differentiation, respiratory system, medicine.disease, respiratory tract diseases, Clone Cells, Organoids, medicine.anatomical_structure, TWEAK Receptor, Alveolar Epithelial Cells, Keratin-5, Single-Cell Analysis, Cell Division
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المؤلفون: Howard Y. Chang, Grace X.Y. Zheng, Brian T. Do, Paul A. Khavari, Dan E. Webster
المصدر: Nature Structural & Molecular Biology. 21:585-590
مصطلحات موضوعية: Ribonuclease III, Transcription, Genetic, Down-Regulation, RNA-binding protein, Cell fate determination, Article, DEAD-box RNA Helicases, Proto-Oncogene Proteins c-myc, Gene Knockout Techniques, Mice, Structural Biology, Transcription (biology), microRNA, Animals, Molecular Biology, Transcription factor, Genetics, biology, RNA-Binding Proteins, eye diseases, Cell biology, MicroRNAs, biology.protein, RNA, Long Noncoding, sense organs, Transcriptome, Dicer
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المؤلفون: Rajiv Bharadwaj, Paul Wyatt, Joe Shuga, Donald A. Masquelier, Tarjei S. Mikkelsen, Mark T. Gregory, Junjie Zhu, Jerald P. Radich, Emily A. Stevens, Solongo B. Ziraldo, Christopher McFarland, Luz Montesclaros, Nolan G. Ericson, Alexander Wong, William J. Valente, Benjamin J. Hindson, Tobias Daniel Wheeler, Jason G. Underwood, H. Joachim Deeg, Jessica M. Terry, Kevin D. Ness, Phillip Belgrader, Stefanie Y. Nishimura, Geoffrey P. McDermott, Michael Schnall-Levin, Jason H. Bielas, Zachary Bent, Lan Beppu, Paul Ryvkin, Christopher Hindson, Grace X.Y. Zheng, Keith R. Loeb, Ryan Wilson
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communicationsمصطلحات موضوعية: Male, 0301 basic medicine, Science, Cell, General Physics and Astronomy, Computational biology, Biology, Peripheral blood mononuclear cell, Article, General Biochemistry, Genetics and Molecular Biology, Cell Line, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Immune system, Single-cell analysis, Gene expression, medicine, Humans, RNA, Messenger, Multidisciplinary, General Chemistry, 030104 developmental biology, medicine.anatomical_structure, Cell culture, Leukocytes, Mononuclear, Female, Bone marrow, Single-Cell Analysis, 030217 neurology & neurosurgery
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المؤلفون: Nolan G. Ericson, Alexander Wong, Keith R. Loeb, Ryan Wilson, Zachary Bent, Emily A. Stevens, Tobias Daniel Wheeler, Rajiv Bharadwaj, H. Joachim Deeg, Jessica M. Terry, William J. Valente, Jason H. Bielas, Kevin D. Ness, Phillip Belgrader, Lan Beppu, Paul Ryvkin, Tarjei S. Mikkelsen, Geoffrey P. McDermott, Jerald P. Radich, Donald A. Masquelier, Solongo B. Ziraldo, Mark T. Gregory, Luz Montesclaros, Grace X.Y. Zheng, Christopher McFarland, Paul Wyatt, Christopher Hindson, Joe Shuga, Stefanie Y. Nishimura, Benjamin J. Hindson, Michael Schnall-Levin, Junjie Zhu
مصطلحات موضوعية: 0303 health sciences, Messenger RNA, Cell, Computational biology, Biology, Bioinformatics, Peripheral blood mononuclear cell, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Immune system, Cell culture, 030220 oncology & carcinogenesis, medicine, Bone marrow, Cell encapsulation, 030304 developmental biology
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المؤلفون: William Stedman, Han Cao, Michael Saghbini, Jason Bobe, Alex Hastie, David Catoe, Arend Sidow, Marc L. Salit, Kristina Giorda, Alexander Wait Zaranek, Stephen T. Sherry, Zeljko Dzakula, Gintaras Deikus, R Truty, Erich Jaeger, Alexa B. R. McIntyre, Karoline Bjarnesdatter Rypdal, Christopher C. Chang, Robert Sebra, Srinka Ghosh, Grace X.Y. Zheng, Jonathan Trow, Yuling Liu, Tiffany Y. Liang, Khoa Pham, Fiona Hyland, Heather Ordonez, Dhruva Chandramohan, Noah Spies, Ziming Weng, Sofia Kyriazopoulou-Panagiotopoulou, Yutao Fu, Eric E. Schadt, Lindsay K. Vang, Ali Bashir, Madeleine Ball, Christopher E. Mason, Preston W. Estep, Keyan Zhao, George M. Church, Justin M. Zook, Ying Sheng, Mark Chaisson, Patrick Marks, Natali Gulbahce, Elizabeth Henaff, Patrice A Mudivarti, Feng Chen, Jennifer McDaniel, Michael Schnall-Levin, Chunlin Xiao, Noah Alexander, Ali Moshrefi
المصدر: Scientific Data
BMC Genomicsمصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Data Descriptor, Standards, Genotype, Sequence assembly, Genomics, Computational biology, Biology, Library and Information Sciences, Polymorphism, Single Nucleotide, Genome, DNA sequencing, Education, 03 medical and health sciences, 0302 clinical medicine, INDEL Mutation, Genome assembly algorithms, Humans, Exome, Internet, Genome, Human, Sequence Analysis, DNA, Computer Science Applications, Personal Genome Project, Benchmarking, 030104 developmental biology, Genetic Techniques, Next-generation sequencing, Human genome, Nanopore sequencing, Statistics, Probability and Uncertainty, Software, 030217 neurology & neurosurgery, Research Article, Information Systems
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المؤلفون: Rajiv Bharadwaj, Hanlee P. Ji, Serge Saxonov, Alex Kindwall, Melissa Luo, Patrick Marks, Clara Bermejo, Landon Merrill, Francesca Meschi, Jessica M. Terry, Adrian Fehr, John Bell, Gerard M Vurens, Kristina Giorda, Adam Lowe, Heather Ordonez, Michael Schnall-Levin, Jorge Bernate, Josephine Y Lee, Phillip Belgrader, Glenn K. Lockwood, Steven W Short, Sukhvinder Kaur, Shawn Gauby, Lawrence Greenfield, Geoffrey P. McDermott, Stephanie Greer, Pranav Patel, Andrew D. Price, Benjamin J. Hindson, Nikola O Kondov, Grace X.Y. Zheng, Sofia Kyriazopoulou-Panagiotopoulou, David E Birch, Luz Montesclaros, Alexander Wong, Kamila Belhocine, Susan M. Grimes, Ryan Wilson, Donald A. Masquelier, Patrice A Mudivarti, Kevin D. Ness, Mirna Jarosz, Adrian Chan, Indira Wu, Erik S. Hopmans, Paul Wyatt, David Stafford, Paul Hardenbol, Anthony J. Makarewicz, Joshua Delaney, Yuan Li, Zachary Bent, Christopher Hindson, Christina Wood, Keith Bjornson, Billy T. Lau, William Haynes Heaton
المصدر: Nature biotechnology, vol 34, iss 3
مصطلحات موضوعية: 0301 basic medicine, Cancer genome sequencing, Oncogene Proteins, Fusion, Biomedical Engineering, Bioengineering, Genomics, Biology, Applied Microbiology and Biotechnology, Polymorphism, Single Nucleotide, DNA sequencing, 03 medical and health sciences, Neoplasms, Humans, Polymorphism, Fusion, Exome sequencing, Whole genome sequencing, Genetics, Oncogene Proteins, Genome, Shotgun sequencing, Genome, Human, High-Throughput Nucleotide Sequencing, Sequence Analysis, DNA, DNA, Single Nucleotide, 3. Good health, 030104 developmental biology, Germ Cells, Haplotypes, Genomic Structural Variation, Molecular Medicine, Nucleic Acid Conformation, Human genome, Sequence Analysis, Biotechnology, Personal genomics, Human
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المؤلفون: Phillip A. Sharp, Amanda G. Young, Andrew D. Bosson, Grace X.Y. Zheng, Cydney B. Nielsen, Anthony K.L. Leung, Arjun Bhutkar
المساهمون: Massachusetts Institute of Technology. Computational and Systems Biology Program, Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Leung, Anthony, Young, Amanda G., Bhutkar, Arjun (AJ), Zheng, Grace X., Bosson, Andrew David, Nielsen, Cydney B., Sharp, Phillip A.
المصدر: Nature structural & molecular biology
PMCمصطلحات موضوعية: Ribonuclease III, Guanine, Population, Eukaryotic Initiation Factor-2, MiRNA binding, Biology, Article, Cell Line, DEAD-box RNA Helicases, 03 medical and health sciences, Mice, 0302 clinical medicine, Structural Biology, microRNA, Endoribonucleases, Coding region, Gene silencing, Animals, education, Molecular Biology, Embryonic Stem Cells, 030304 developmental biology, Regulation of gene expression, Genetics, 0303 health sciences, education.field_of_study, Binding Sites, Base Sequence, Sequence Analysis, RNA, RNA, High-Throughput Nucleotide Sequencing, Argonaute, 3. Good health, MicroRNAs, Gene Expression Regulation, Argonaute Proteins, 030217 neurology & neurosurgery, Gene Deletion, Protein Binding
وصف الملف: application/pdf
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