المؤلفون: Satya Prakash Khuntia, Nilesh Mukherjee, Vyomesh Javle, Nishtha AjitSingh Tanwar, Peddagangannagari Sreekanthreddy, Linu Varghese, Pooja Gowda, Anju Kottlahouse, Pratik Chandrani, Anuradha Choughule, Priyanka Pange, Vinod Gupta, Vanita Noronha, Vijay Maruti Patil, Raja Pramanik, Sunil Kumar, Sandeep Peraje Nayak, Suresh Babu, Rohan Shetty, Madan Kantharaju, Pramod Shekarappa Chinder, Aruna Korlimarla, B.S. Srinath, Kumar Prabhash, Giridharan Periyasamy, Kshitij Datta Rishi, Hitesh Madan Goswami, Vidya Harini Veldore

المصدر: JCO Global Oncology, Iss 10 (2024)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2687-8941

URL الوصول: https://doaj.org/article/bb809873ffc2475785b0f4083c8fb4ee

المؤلفون: Li Ren Kong, Richard Weijie Ong, Tuan Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, Miyoung Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Chwee Ming Lim, Wee Joo Chng, David P. Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/89ea4992ac4f465ea6d7ca0e0a05a0dd

المؤلفون: Rachel L. Y. Wong, Megan R. E. Wong, Chik Hong Kuick, Seyed Ehsan Saffari, Meng Kang Wong, Sheng Hui Tan, Khurshid Merchant, Kenneth T. E. Chang, Matan Thangavelu, Giridharan Periyasamy, Zhi Xiong Chen, Prasad Iyer, Enrica E. K. Tan, Shui Yen Soh, N. Gopalakrishna Iyer, Qiao Fan, Amos H. P. Loh

المصدر: Frontiers in Oncology, Vol 11 (2021)

مصطلحات موضوعية: neuroblastoma, patient-derived culture, copy number variations (CNV), Comprehensive genomic profiling (CGP), PI3K - AKT pathway, CDK (cyclin-dependent kinase), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.709525/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/c94105f2a340474b8a92a8bcd7d1fcc0

المؤلفون: Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta

المصدر: EBioMedicine, Vol 66, Iss , Pp 103297- (2021)

مصطلحات موضوعية: Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396421000906; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/efc7e7970bf04a188a2b4cbd40df635d

المؤلفون: Joo-Leng Low, Dawn Pingxi Lau, Xiaoqian Zhang, Xue-Lin Kwang, Neha Rohatgi, Jane Vin Chan, Fui-Teen Chong, Stephen Qi Rong Wong, Hui-Sun Leong, Matan Thangavelu Thangavelu, Shivaji Rikka, Anders Martin Jacobsen Skanderup, Daniel Shao Weng Tan, Giridharan Periyasamy, Judice Lie Yong Koh, N Gopalakrishna Iyer, Ramanuj DasGupta

المصدر: EBioMedicine, Vol 64, Iss , Pp 103220- (2021)

مصطلحات موضوعية: Head and neck squamous cell carcinoma, Gefitinib resistance, Aurora kinase inhibition, EGFR T790M negative, Chemical genetics, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235239642100013X; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/a859aa922a95418fb03d43002f362811

المؤلفون: Ankur Sharma, Elaine Yiqun Cao, Vibhor Kumar, Xiaoqian Zhang, Hui Sun Leong, Angeline Mei Lin Wong, Neeraja Ramakrishnan, Muhammad Hakimullah, Hui Min Vivian Teo, Fui Teen Chong, Shumei Chia, Matan Thangavelu Thangavelu, Xue Lin Kwang, Ruta Gupta, Jonathan R. Clark, Giridharan Periyasamy, N. Gopalakrishna Iyer, Ramanuj DasGupta

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/4c8180ac64824e05a63db761c9056b3c

المؤلفون: Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, Xue-Lin Kwang, Fui-Teen Chong, Ankur Sharma, Denis Bertrand, Shen Yon Toh, Hui-Sun Leong, Matan T. Thangavelu, Jacqueline S. G. Hwang, Kok-Hing Lim, Thakshayeni Skanthakumar, Hiang-Khoon Tan, Yan Su, Siang Hui Choo, Hannes Hentze, Iain B. H. Tan, Alexander Lezhava, Patrick Tan, Daniel S. W. Tan, Giridharan Periyasamy, Judice L. Y. Koh, N. Gopalakrishna Iyer, Ramanuj DasGupta

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/7f061de7c66f4a4eb132f00dff006462

المؤلفون: Wei Xiang, Yi Hui Lam, Giridharan Periyasamy, Charles Chuah

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2863

مصطلحات موضوعية: high throughput, drug screening, AI, leukemia, personalized medicine

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms23052863

الاتاحة: https://doi.org/10.3390/ijms23052863

المؤلفون: Shrikant Anant, Somesh Sharma, Arun Balakrishnan, Scott J. Weir, Muralidhara Padigaru, Aravind Sugumar, Debarshi Chakrabarti, Sivapriya Ponnurangam, Giridharan Periyasamy, Dharmalingam Subramaniam

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a4de6be9c0a79913f36e27e7e5b959
https://doi.org/10.1158/1535-7163.22499176.v1

المؤلفون: Shrikant Anant, Somesh Sharma, Arun Balakrishnan, Scott J. Weir, Muralidhara Padigaru, Aravind Sugumar, Debarshi Chakrabarti, Sivapriya Ponnurangam, Giridharan Periyasamy, Dharmalingam Subramaniam

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f67b4e9ae0ff5e5add64002a28940185
https://doi.org/10.1158/1535-7163.c.6536086

المؤلفون: Tuan Zea Tan, Srinivasaraghavan Kannan, Lingzhi Wang, Thi Bich Uyen Le, Richard Weijie Ong, Giridharan Periyasamy, Chandra S. Verma, Nur Afiqah Binte Mohamed Salleh, Jane Vin Chan, Li Ren Kong, David P. Lane, Matan Thangavelu Thangavelu, Chit Fang Cheok, Wee Joo Chng, Chwee Ming Lim, Lie Yong Judice Koh, Jieying Amelia Lau, Ashok R. Venkitaraman, Miyoung Lee, Boon Cher Goh

المساهمون: Kong, Li Ren [0000-0001-7980-4666], Tan, Tuan Zea [0000-0001-6624-1593], Kannan, Srinivasaraghavan [0000-0002-9539-5249], Lane, David P [0000-0003-0551-3545], Goh, Boon Cher [0000-0002-4107-102X], Apollo - University of Cambridge Repository, Lane, David P. [0000-0003-0551-3545]

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, 82/29, Mutant, 96, 45/44, General Physics and Astronomy, Apoptosis, Mice, SCID, 13, Hydroxamic Acids, 14, 96/31, Epigenesis, Genetic, 13/2, 13/1, chemistry.chemical_compound, 0302 clinical medicine, Neoplasms, Histone methylation, Protein Isoforms, 14/19, lcsh:Science, 13/89, Regulation of gene expression, 45/70, Sulfonamides, Multidisciplinary, biology, Caspase 3, Chemistry, 82/79, High-throughput screening, NF-kappa B, Acetylation, Chromatin, Ubiquitin ligase, Gene Expression Regulation, Neoplastic, 631/67/1059/602, Gain of Function Mutation, 030220 oncology & carcinogenesis, 38/39, 64/60, Poly(ADP-ribose) Polymerases, Protein Binding, 631/80/82/23, 101, Ubiquitin-Protein Ligases, Science, Antineoplastic Agents, 13/109, Models, Biological, Article, General Biochemistry, Genetics and Molecular Biology, 38, 03 medical and health sciences, Targeted therapies, Cell Line, Tumor, Animals, Humans, 96/1, Nucleotide Motifs, Codon, Cell Proliferation, 49/15, General Chemistry, DNA-binding domain, Xenograft Model Antitumor Assays, 49, 030104 developmental biology, 13/51, Mutation, biology.protein, Cancer research, lcsh:Q, Mutant Proteins, 631/154/1435/2163, Cisplatin, Tumor Suppressor Protein p53, Topotecan, DNA

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990d623049641fe5d64ca8c5af033a18
https://doaj.org/article/89ea4992ac4f465ea6d7ca0e0a05a0dd

المؤلفون: Balakrishnan Chakrapani Narmada, Atefeh Khakpoor, Niranjan Shirgaonkar, Sriram Narayanan, Pauline Poh Kim Aw, Malay Singh, Kok Haur Ong, Collins Oduor Owino, Jane Wei Ting Ng, Hui Chuing Yew, Nu Soibah Binte Mohamed Nasir, Veonice Bijin Au, Reina Sng, Nivashini Kaliaperumal, Htet Htet Toe Wai Khine, Hui Xin Ng, Su Li Chia, Cindy Xin Yi Seah, Myra HJ Alnawaz, Chris Lee Yoon Wai, Amy Yuh Ling Tay, Weimiao Yu, John Edward Connolly, Giridharan Periyasamy, Seng Gee Lim, Ramanuj Dasgupta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3fed587114bdba974912ed8bd5f397fe
https://doi.org/10.1101/2022.04.26.489625

المؤلفون: Raghuvaran Shanmugam, Mert Burak Ozturk, Joo-Leng Low, Semih Can Akincilar, Joelle Yi Heng Chua, Matan Thangavelu Thangavelu, Giridharan Periyasamy, Ramanuj DasGupta, Vinay Tergaonkar

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: Gene Editing, Multidisciplinary, Mediator Complex, Transcription, Genetic, TERT, Cell Biology, Biological Sciences, Regulatory Sequences, Nucleic Acid, telomerase, Chromatin, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Cell Line, Tumor, Neoplasms, Mutation, cancer, Humans, CRISPR-Cas Systems, Promoter Regions, Genetic, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50d8619f3a4f5939ed7d95981748539
http://europepmc.org/articles/PMC8784157

المؤلفون: Collins Oduor Owino, Yi Lin Gian, Pauline AW Poh Kim, Nivrithi Ganesh, Balakrishnan Chakrapani Narmada, Giridharan Periyasamy, Pablo Bifani, Ramanuj Dasgupta

المصدر: Journal of Hepatology. 77:S98-S99

مصطلحات موضوعية: Hepatology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47a5d5dff36048b1aed5d0afb2676090
https://doi.org/10.1016/s0168-8278(22)00586-4

المؤلفون: Neha Rohatgi, Hui-Sun Leong, Anders Jacobsen Skanderup, Stephen Qi Rong Wong, Giridharan Periyasamy, Matan Thangavelu Thangavelu, Judice Lie Yong Koh, Fui-Teen Chong, Xiaoqian Zhang, Ramanuj DasGupta, N. Gopalakrishna Iyer, Dawn Pingxi Lau, Daniel Shao Weng Tan, Jane Vin Chan, Xue-Lin Kwang, Joo-Leng Low, Shivaji Rikka

المصدر: EBioMedicine
EBioMedicine, Vol 64, Iss, Pp 103220-(2021)

مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, General Biochemistry, Genetics and Molecular Biology, Chemical genetics, 03 medical and health sciences, 0302 clinical medicine, Aurora kinase, Gefitinib, Cyclin-dependent kinase, medicine, Epidermal growth factor receptor, lcsh:R5-920, Aurora kinase inhibition, Gefitinib resistance, biology, Cetuximab, Cell growth, lcsh:R, Head and neck squamous cell carcinoma, EGFR T790M negative, General Medicine, medicine.disease, Head and neck squamous-cell carcinoma, 030104 developmental biology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, lcsh:Medicine (General), Tyrosine kinase, medicine.drug, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dcccf2052f09a24788f4cb30b03414
http://europepmc.org/articles/PMC7851772

المؤلفون: Ragavan, Ramasamy, Kumar, Kalavathi, Vijayakumar, Vijayaparthasarathi, Sarveswari, Sundaramoorthy, Ramaiah, Sudha, Anbarasu, Anand, Karthikeyan, Sivashanmugam, Giridharan, Periyasamy, Kumari, Nalilu

مصطلحات موضوعية: β-keto esters, Ethyl chloroformate, Pyrazolones, Efficient synthesis, Anti-bacterial activity, Fungicidal activity, Cytotoxicity studies

Relation: http://www.orgmedchemlett.com/content/3/1/6

الاتاحة: http://www.orgmedchemlett.com/content/3/1/6

المؤلفون: Ragavan, Ramasamy Venkat, Kumar, Kalavathi Murugan, Vijayakumar, Vijayaparthasarathi, Sarveswari, Sundaramoorthy, Ramaiah, Sudha, Anbarasu, Anand, Karthikeyan, Sivashanmugam, Giridharan, Periyasamy, Kumari, Nalilu Suchetha

المصدر: Organic and Medicinal Chemistry Letters ; volume 3, issue 1 ; ISSN 2191-2858

الاتاحة: http://dx.doi.org/10.1186/2191-2858-3-6
https://link.springer.com/content/pdf/10.1186/2191-2858-3-6.pdf

المؤلفون: Matan Thangavelu Thangavelu, Hui Min Vivian Teo, Fui Teen Chong, Jonathan R. Clark, Ankur Sharma, Ruta Gupta, Muhammad Hakimullah, Giridharan Periyasamy, Vibhor Kumar, Elaine Yiqun Cao, Xue Lin Kwang, Neeraja Ramakrishnan, Hui Sun Leong, Shumei Chia, N. Gopalakrishna Iyer, Angeline Mei Lin Wong, Xiaoqian Zhang, Ramanuj DasGupta

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)

مصطلحات موضوعية: 0301 basic medicine, Science, Cell, General Physics and Astronomy, Antineoplastic Agents, Mice, SCID, 02 engineering and technology, Biology, General Biochemistry, Genetics and Molecular Biology, Transcriptome, Genetic Heterogeneity, 03 medical and health sciences, SOX2, Mice, Inbred NOD, Cell Line, Tumor, medicine, Animals, Humans, Epigenetics, lcsh:Science, Mice, Knockout, Regulation of gene expression, Multidisciplinary, Sequence Analysis, RNA, Gene Expression Profiling, General Chemistry, 021001 nanoscience & nanotechnology, Xenograft Model Antitumor Assays, Phenotype, Chromatin, Cell biology, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Drug Resistance, Neoplasm, Carcinoma, Squamous Cell, Neoplastic Stem Cells, Mouth Neoplasms, lcsh:Q, Cisplatin, Single-Cell Analysis, Stem cell, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4c35230fb0d13f481edfbf7ae2f565
https://doaj.org/article/4c8180ac64824e05a63db761c9056b3c

المؤلفون: Rachel L. Y. Wong (11562280), Megan R. E. Wong (11562283), Chik Hong Kuick (7483370), Seyed Ehsan Saffari (8068367), Meng Kang Wong (11562286), Sheng Hui Tan (11562289), Khurshid Merchant (11562292), Kenneth T. E. Chang (8976572), Matan Thangavelu (11562295), Giridharan Periyasamy (11562298), Zhi Xiong Chen (9248660), Prasad Iyer (5159711), Enrica E. K. Tan (8976566), Shui Yen Soh (11562301), N. Gopalakrishna Iyer (9565648), Qiao Fan (159308), Amos H. P. Loh (11562304)

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, neuroblastoma, patient-derived culture, copy number variations (CNV), Comprehensive genomic profiling (CGP), PI3K - AKT pathway, CDK (cyclin-dependent kinase), JAK-STAT cascade

Relation: https://figshare.com/articles/dataset/DataSheet_3_Integrated_Genomic_Profiling_and_Drug_Screening_of_Patient-Derived_Cultures_Identifies_Individualized_Copy_Number-Dependent_Susceptibilities_Involving_PI3K_Pathway_and_17q_Genes_in_Neuroblastoma_xlsx/16809391

الاتاحة: https://doi.org/10.3389/fonc.2021.709525.s003