المؤلفون: William A Munoz, Moonsup Lee, Rachel K Miller, Zamal Ahmed, Hong Ji, Todd M Link, Gilbert R Lee, Malgorzata Kloc, John E Ladbury, Pierre D McCrea

المصدر: PLoS ONE, Vol 9, Iss 1, p e86784 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3903613?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b91cde92093a48ddb3a19d1492599eea

المؤلفون: Gilbert R. Lee, Florian L. Muller, John M. Asara, Todd M. Link, Federica Pisaneschi, Barbara Czako, Y. Alan Wang, Duoli Sun, William G. Bornmann, Yu Hsi Lin, Ronald A. DePinho, Paul G. Leonard, David Maxwell, Maria Emilia Di Francesco, Naima Hammoudi, Nikunj Satani, Basvoju A. Bhanu Prasad, Zhenghong Peng

المصدر: Nature chemical biology

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Enolase, Organophosphonates, Cancer therapy, Article, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Glioma, medicine, Humans, Enzyme Inhibitor, Glycolysis, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Cell Biology, medicine.disease, Phosphonate, Molecular biology, Pyrrolidinones, Metabolic pathway, 030104 developmental biology, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, Phosphopyruvate Hydratase, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7fe16601d682c58a159c49b4a33d58
https://doi.org/10.1038/nchembio.2195

المؤلفون: Yi, Du, Hirohito, Yamaguchi, Yongkun, Wei, Jennifer L, Hsu, Hung-Ling, Wang, Yi-Hsin, Hsu, Wan-Chi, Lin, Wen-Hsuan, Yu, Paul G, Leonard, Gilbert R, Lee, Mei-Kuang, Chen, Katsuya, Nakai, Ming-Chuan, Hsu, Chun-Te, Chen, Ye, Sun, Yun, Wu, Wei-Chao, Chang, Wen-Chien, Huang, Chien-Liang, Liu, Yuan-Ching, Chang, Chung-Hsuan, Chen, Morag, Park, Philip, Jones, Gabriel N, Hortobagyi, Mien-Chie, Hung

المصدر: Nature medicine

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e7324d2fbec5ea11ca66424121a6ea6a
https://pubmed.ncbi.nlm.nih.gov/26779812

المؤلفون: Gilbert R. Lee, Pietro Morlacchi, J. Morgan Knight, John E. Ladbury, John S. McMurray, Todd M. Link, Lydia E. Kavraki, Ankur Dhanik, Pijus K. Mandal, Divyendu Singh, David B. Corry, Roza Nurieva

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Models, Molecular, Phosphopeptides, Transcriptional Activation, Phosphatase, SH2 domain, Article, Cell Line, src Homology Domains, Mice, Structure-Activity Relationship, Drug Discovery, Animals, Prodrugs, Phosphorylation, Receptor, STAT6, Interleukin-13, Dose-Response Relationship, Drug, Chemistry, Phosphopeptide, respiratory system, Asthma, Phosphoric Monoester Hydrolases, Receptors, Interleukin-3, Rats, Receptors, Interleukin-4, Mice, Inbred C57BL, Biochemistry, Gene Expression Regulation, STAT protein, Molecular Medicine, Tyrosine, Interleukin-4, STAT6 Transcription Factor, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd45b802fbb0a7c8a0d4f4c1c052ee76
https://europepmc.org/articles/PMC5109833/

المؤلفون: John E. Ladbury, Chi-Chuan Lin, Kin Man Suen, Nathan P. Cook, Angel A. Martí, Zahra Timsah, Gilbert R. Lee, Zamal Ahmed, Mihai Gagea

المصدر: Nature Communications. 6

مصطلحات موضوعية: Physics, Fluorescence intensity, Crystallography, Multidisciplinary, Pixel, Labelling, General Physics and Astronomy, General Chemistry, Monomer dimer, Function (mathematics), General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aae181b729af4a1637a2a867dc8cb8f2
https://doi.org/10.1038/ncomms9007

المؤلفون: Kin Man Suen, Angel A. Martí, Chi-Chuan Lin, Nathan P. Cook, Zahra Timsah, Mihai Gagea, Zamal Ahmed, Gilbert R. Lee, John E. Ladbury

المصدر: Nature Communications

مصطلحات موضوعية: Multidisciplinary, General Physics and Astronomy, General Chemistry, Protein tyrosine phosphatase, Biology, SH2 domain, General Biochemistry, Genetics and Molecular Biology, Receptor tyrosine kinase, SH3 domain, Article, MAP2K7, Biochemistry, biology.protein, GRB2, c-Raf, biological phenomena, cell phenomena, and immunity, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3d545d9b754271e291da7ddbe458c4
http://europepmc.org/articles/PMC4491180

المؤلفون: Gilbert R. Lee, Mario Cardozo, Xi Shi, Jennifer Bardenhagen, Philip Jones, Alessia Petrocchi, Paul G. Leonard, Wylie S. Palmer, Yanai Zhan, John E. Ladbury, G. Poncet-Montange, Mary K. Geck Do, Jannik N. Andersen, Elisabetta Leo

المصدر: The Biochemical journal. 466(2)

مصطلحات موضوعية: Conformational change, Protein Conformation, Peptide, Antineoplastic Agents, Ligands, Biochemistry, Article, Histones, Protein structure, Humans, Biotinylation, Protein Interaction Domains and Motifs, Binding site, Enzyme Inhibitors, Pliability, Molecular Biology, chemistry.chemical_classification, Adenosine Triphosphatases, Sulfonamides, Binding Sites, biology, Cell Biology, Isoxazoles, Small molecule, AAA proteins, Peptide Fragments, Recombinant Proteins, meta-Aminobenzoates, Bromodomain, DNA-Binding Proteins, Kinetics, Histone, chemistry, Drug Design, biology.protein, ATPases Associated with Diverse Cellular Activities, Mutant Proteins, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c2b89543d804087a82e5650be05e4d
https://pubmed.ncbi.nlm.nih.gov/25486442

المؤلفون: Malgorzata Kloc, Moonsup Lee, Pierre D. McCrea, Hong Ji, Gilbert R. Lee, Rachel K. Miller, William A. Munoz, Zamal Ahmed, John E. Ladbury, Todd M. Link

المصدر: PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e86784 (2014)

مصطلحات موضوعية: Embryology, Embryo, Nonmammalian, Organogenesis, Xenopus, lcsh:Medicine, Fluorescent Antibody Technique, Plakophilin, Biochemistry, Mice, Xenopus laevis, 0302 clinical medicine, Molecular cell biology, Desmosome, lcsh:Science, In Situ Hybridization, WNT Signaling Cascade, Neurons, 0303 health sciences, Multidisciplinary, biology, Stem Cells, Cell Differentiation, Animal Models, 16. Peace & justice, Cadherins, Signaling Cascades, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cellular Types, Research Article, Signal Transduction, Adhesion Molecules, Immunoblotting, DNA transcription, Real-Time Polymerase Chain Reaction, Signaling Pathways, 03 medical and health sciences, Catenin Signal Transduction, Model Organisms, Two-Hybrid System Techniques, DNA-binding proteins, medicine, Cell Adhesion, Animals, Humans, Immunoprecipitation, Desmosomal Cadherins, Transcription factor, Biology, Embryonic Stem Cells, 030304 developmental biology, DNA Primers, Cell Nucleus, lcsh:R, Proteins, Protein interactions, Molecular Development, biology.organism_classification, Molecular biology, Cell nucleus, HEK293 Cells, Gene Expression Regulation, Catenin, lcsh:Q, Gene expression, Plakophilins, Organism Development, Nuclear localization sequence, HeLa Cells, Transcription Factors, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c942d2703a07b0c605455209a399f0
https://pubmed.ncbi.nlm.nih.gov/24475179

المؤلفون: Nikunj Satani, M. Di Francesco, Joseph R. Marszalek, Zhenghong Peng, Duoli Sun, Federica Pisaneschi, Florian L. Muller, Barbara Czako, Alan Y. Wang, Yu-Hsi Lin, David Maxwell, Naima Hammoudi, Todd M. Link, Paul G. Leonard, William G. Bornmann, John S. McMurray, Gilbert R. Lee, Ronald A. DePinho, Yuting Sun, Pijus K. Mandal

المصدر: European Journal of Cancer. 69:S124

مصطلحات موضوعية: Cancer Research, medicine.anatomical_structure, Oncology, Chemistry, Cell, Enolase, Cancer research, medicine, Lethality, medicine.disease, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48dca1f3fb2779d2f6a803ba969616bd
https://doi.org/10.1016/s0959-8049(16)32968-9

المؤلفون: Gilbert R. Lee, Ye Sun, Yi Hsin Hsu, Yi Du, Ming-Chuan Hsu, Chien Liang Liu, Katsuya Nakai, Wen-Hsuan Yu, Mien Chie Hung, Wan Chi Lin, Hung-Ling Wang, Yongkun Wei, Hirohito Yamaguchi, Chung-Hsuan Chen, Wen-Chien Huang, Chun-Te Chen, Mei-Kuang Chen, Gabriel N. Hortobagyi, Yun Wu, Paul G. Leonard, Wei Chao Chang, Jennifer L. Hsu, Yuan-Ching Chang, Philip H. Jones, Morag Park

المصدر: Nature Medicine. 22:1192-1192

مصطلحات موضوعية: inorganic chemicals, 0301 basic medicine, Antitumor activity, C-Met, Chemistry, Blocking (radio), Poly ADP ribose polymerase, macromolecular substances, General Medicine, environment and public health, General Biochemistry, Genetics and Molecular Biology, enzymes and coenzymes (carbohydrates), 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, PARP1, Cancer research, bacteria, Phosphorylation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0dd8f4c108c1c432c74d65b8bed0ea45
https://doi.org/10.1038/nm1016-1192c

المؤلفون: Alan Y. Want, Todd M. Link, Maria Emilia Di Francesco, Yuting Sun, Barbara Czako, Gilbert R. Lee, Paul G. Leonard, Ronald A. DePinho, Peng Zhang, David Maxwell, Nikunj Satani, Yu-Hsi Lin, Joe Marszalek, Florian L. Muller, Naima Hammoudi

المصدر: Molecular Cancer Therapeutics. 14:C183-C183

مصطلحات موضوعية: Cancer Research, Enolase, Cell, Cancer, Biology, medicine.disease, In vitro, Glycolysis Inhibition, medicine.anatomical_structure, Oncology, In vivo, Cell culture, Glioma, Immunology, medicine, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b9f63752c0fda87ea144f4c39d69ac31
https://doi.org/10.1158/1535-7163.targ-15-c183

المؤلفون: PijusK. Mandal, Pietro Morlacchi, J. Morgan Knight, Todd M. Link, Gilbert R. Lee, Roza Nurieva, Divyendu Singh, Ankur Dhanik, Lydia Kavraki, DavidB. Corry, John E. Ladbury, John S. McMurray

المصدر: Journal of Medicinal Chemistry; Nov2015, Vol. 58 Issue 22, p8970-8984, 15p