المؤلفون: Porter, A, Barcelon, JM, Budker, RL, Marsh, L, Moriarty, JM, Aguiar, X, Rao, J, Ghorani, E, Kaur, B, Maher, G, Seckl, MJ, Konecny, GE, Cohen, JG

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Cancer, Clinical Research, Immunization, Vaccine Related, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Placental site trophoblastic tumor, Immunotherapy, Pembrolizumab

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9t52n4mh
https://escholarship.org/content/qt9t52n4mh/qt9t52n4mh.pdf

المؤلفون: Ghorani, E, Quartagno, M, Blackhall, F, Gilbert, DC, O'Brien, M, Ottensmeier, C, Pizzo, E, Spicer, J, Williams, A, Badman, P, Parmar, MKB, Seckl, MJ, on behalf of the REFINE-Lung, Investigators

المصدر: The Lancet Oncology , 24 (5) e219-e227. (2023)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10169517/3/Quartagno_Refine-lung%20joint%20paper_v9.pdf; https://discovery.ucl.ac.uk/id/eprint/10169517/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10169517/3/Quartagno_Refine-lung%20joint%20paper_v9.pdf
https://discovery.ucl.ac.uk/id/eprint/10169517/

المؤلفون: Ghorani, E, Quartagno, M, Blackhall, F, Gilbert, DC, O'Brien, M, Ottensmeier, C, Pizzo, E, Spicer, J, Williams, A, Badman, P, Parmar, MKB, Seckl, MJ

المصدر: E227 ; E219

Relation: The Lancet Oncology; http://hdl.handle.net/10044/1/107872

الاتاحة: http://hdl.handle.net/10044/1/107872
https://doi.org/10.1016/S1470-2045(23)00095-5

المؤلفون: Au, L, Hatipoglu, E, Robert de Massy, M, Litchfield, K, Beattie, G, Rowan, A, Schnidrig, D, Thompson, R, Byrne, F, Horswell, S, Fotiadis, N, Hazell, S, Nicol, D, Shepherd, STC, Fendler, A, Mason, R, Del Rosario, L, Edmonds, K, Lingard, K, Sarker, S, Mangwende, M, Carlyle, E, Attig, J, Joshi, K, Uddin, I, Becker, PD, Sunderland, MW, Akarca, A, Puccio, I, Yang, WW, Lund, T, Dhillon, K, Vasquez, MD, Ghorani, E, Xu, H, Spencer, C, López, JI, Green, A, Mahadeva, U, Borg, E, Mitchison, M, Moore, DA, Proctor, I, Falzon, M, Pickering, L, Furness, AJS, Reading, JL, Salgado, R, Marafioti, T, Jamal-Hanjani, M, PEACE Consortium, Kassiotis, G, Chain, B, Larkin, J, Swanton, C, Quezada, SA, Turajlic, S, TRACERx Renal Consortium

المساهمون: Au, Lewis, Shepherd, Scott, Furness, Andrew

مصطلحات موضوعية: PEACE Consortium, TRACERx Renal Consortium, CD8-Positive T-Lymphocytes, Humans, Endogenous Retroviruses, Carcinoma, Renal Cell, Kidney Neoplasms, Receptors, Antigen, T-Cell, Prospective Studies, Gene Expression Profiling, Sequence Analysis, RNA, Genomics, Tumor Escape, Drug Resistance, Neoplasm, Clinical Trials, Phase II as Topic, Single-Cell Analysis, Tumor Microenvironment, Whole Exome Sequencing, Nivolumab, Immune Checkpoint Inhibitors

وصف الملف: Print-Electronic; 1518.e11; application/pdf

Relation: Cancer cell, 2021, 39 (11), pp. 1497 - 1518.e11; https://repository.icr.ac.uk/handle/internal/4993

الاتاحة: https://repository.icr.ac.uk/handle/internal/4993
https://doi.org/10.1016/j.ccell.2021.10.001

المؤلفون: Maher, G, Fisher, RA, Kaur, B, Aguiar, X, Aravind, P, Cedeno, N, Clark, J, Damon, D, Ghorani, E, Januszewski, A, Kalofonou, F, Murphy, R, Roy, R, Sarwar, N, Openshaw, MR, Seckl, MJ

المساهمون: Rosetrees Trust

المصدر: 8 ; 1

Relation: npj Genomic Medicine; http://hdl.handle.net/10044/1/95132; Seedcorn 2020\100003

الاتاحة: http://hdl.handle.net/10044/1/95132
https://doi.org/10.1038/s41525-022-00297-x

المؤلفون: Qing, C, Ghorani, E, Solomon, I, Gálvez-Cancino, F, Vargas, F, Peggs, K, Quezada, S

المصدر: E-Poster Presentations ; page A31.2-A32

الاتاحة: http://dx.doi.org/10.1136/jitc-2020-itoc7.61
https://syndication.highwire.org/content/doi/10.1136/jitc-2020-ITOC7.61

المؤلفون: Ghorani, E, Reading, J, Henry, J, Robert de Massy, M, Rosenthal, R, Turati, V, Furness, A, Ben Aissa, A, Kumar Saini, S, Ramskov, S, Georgiou, A, Vila De Mucha, M, Uddin, I, Ronel, T, Salgado, R, Lund, T, Herrero, J, Enver, T, Hadrup, S, Hackshaw, A, Peggs, K, McGranahan, N, Chain, B, Swanton, C, Quezada, S

المصدر: E-Poster Presentations ; page A35.1-A35

الاتاحة: http://dx.doi.org/10.1136/jitc-2020-itoc7.68
https://syndication.highwire.org/content/doi/10.1136/jitc-2020-ITOC7.68

المؤلفون: Au, L, Hatipoglu, E, Robert de Massy, M, Litchfield, K, Beattie, G, Rowan, A, Schnidrig, D, Thompson, R, Byrne, F, Horswell, S, Fotiadis, N, Hazell, S, Nicol, D, Shepherd, STC, Fendler, A, Mason, R, Del Rosario, L, Edmonds, K, Lingard, K, Sarker, S, Mangwende, M, Carlyle, E, Attig, J, Joshi, K, Uddin, I, Becker, PD, Sunderland, MW, Akarca, A, Puccio, I, Yang, WW, Lund, T, Dhillon, K, Vasquez, MD, Ghorani, E, Xu, H, Spencer, C, López, JI, Green, A, Mahadeva, U, Borg, E, Mitchison, M, Moore, DA, Proctor, I, Falzon, M, Pickering, L, Furness, AJS, Reading, JL, Salgado, R, Marafioti, T, Jamal-Hanjani, M, PEACE Consortium, Kassiotis, G, Chain, B, Larkin, J, Swanton, C, Quezada, SA, Turajlic, S, TRACERx Renal Consortium

المصدر: Cancer Cell , 39 pp. 1497-1518. (2021)

مصطلحات موضوعية: T cell receptor, TCR clonal maintenance, TCR clonal replacement, anti-PD-1, autopsy, clear cell renal cell carcinoma, human endogenous retrovirus, multiregion, nivolumab

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10137633/1/1-s2.0-S1535610821005432-main.pdf; https://discovery.ucl.ac.uk/id/eprint/10137633/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10137633/1/1-s2.0-S1535610821005432-main.pdf
https://discovery.ucl.ac.uk/id/eprint/10137633/

المؤلفون: Seckl, M., Ghorani, E., Quartagno, M., Blackhall, Fiona H, Gilbert, D. C., O'Brien, M. E. R., Ottensmeier, C. H. H., Pizzo, E., Spicer, J. F., Williams, A., Badman, P. D., Parmar, M. K. B.

المساهمون: Imperial College London, London

Relation: https://dx.doi.org/10.1200/JCO.2023.41.16_suppl.TPS9145; Seckl M, Ghorani E, Quartagno M, Blackhall FH, Gilbert DC, O'Brien MER, et al. REFINE-Lung: A multicentre phase III study to determine the optimal frequency of pembrolizumab in non-small cell lung cancer utilising a novel multi-arm design. Journal of Clinical Oncology. 2023 Jun;41(16). PubMed PMID: WOS:001053772005494.; http://hdl.handle.net/10541/626665; Journal of Clinical Oncology

الاتاحة: http://hdl.handle.net/10541/626665
https://doi.org/10.1200/JCO.2023.41.16_suppl.TPS9145

المؤلفون: Solomon, I, Amann, M, Goubier, A, Vargas, FA, Zervas, D, Qing, C, Henry, JY, Ghorani, E, Akarca, AU, Marafioti, T, Śledzińska, A, Sunderland, MW, Demane, DF, Clancy, JR, Georgiou, A, Salimu, J, Merchiers, P, Brown, MA, Flury, R, Eckmann, J, Murgia, C, Sam, J, Jacobsen, B, Marrer-Berger, E, Boetsch, C, Belli, S, Leibrock, L, Benz, J, Koll, H, Sutmuller, R, Peggs, KS, Quezada, SA

المصدر: Nature Cancer , 1 (12) pp. 1153-1166. (2020)

مصطلحات موضوعية: Antibody therapy, Cancer, Cancer therapy, Immunotherapy, Tumour immunology

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10127795/1/Solomon%20CD25%20Nature%20Cancer%202020-preprint.pdf; https://discovery.ucl.ac.uk/id/eprint/10127795/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10127795/1/Solomon%20CD25%20Nature%20Cancer%202020-preprint.pdf
https://discovery.ucl.ac.uk/id/eprint/10127795/

المؤلفون: Ghorani, E, Reading, JL, Henry, JY, Massy, MRD, Rosenthal, R, Turati, V, Joshi, K, Furness, AJS, Ben Aissa, A, Saini, SK, Ramskov, S, Georgiou, A, Sunderland, MW, Wong, YNS, Mucha, MVD, Day, W, Galvez-Cancino, F, Becker, PD, Uddin, I, Oakes, T, Ismail, M, Ronel, T, Woolston, A, Jamal-Hanjani, M, Veeriah, S, Birkbak, NJ, Wilson, GA, Litchfield, K, Conde, L, Guerra-Assunção, JA, Blighe, K, Biswas, D, Salgado, R, Lund, T, Bakir, MA, Moore, DA, Hiley, CT, Loi, S, Sun, Y, Yuan, Y, AbdulJabbar, K, Turajilic, S, Herrero, J, Enver, T, Hadrup, SR, Hackshaw, A, Peggs, KS, McGranahan, N, Chain, B, Swanton, C, Quezada, SA

المصدر: Nature Cancer , 1 (5) pp. 546-561. (2020)

مصطلحات موضوعية: Cancer, Cancer genomics, Lung cancer, T cells, Tumour immunology

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10102900/11/Reading_The%20T%20cell%20differentiation%20landscape%20is%20shaped%20by%20tumour%20mutations%20in%20lung%20cancer_AAM2.pdf; https://discovery.ucl.ac.uk/id/eprint/10102900/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10102900/11/Reading_The%20T%20cell%20differentiation%20landscape%20is%20shaped%20by%20tumour%20mutations%20in%20lung%20cancer_AAM2.pdf
https://discovery.ucl.ac.uk/id/eprint/10102900/

المؤلفون: Alrasheed, N, Lee, L, Ghorani, E, Henry, JY, Conde, L, Chin, M, Galas-Filipowicz, D, Furness, AJS, Chavda, SJ, Richards, H, De-Silva, D, Cohen, OC, Patel, D, Brooks, A, Rodriguez-Justo, M, Pule, M, Herrero, J, Quezada, SA, Yong, KL

المصدر: Clinical Cancer Research , 26 (13) pp. 3443-3454. (2020)

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10094462/1/1078-0432.CCR-19-1714.full.pdf; https://discovery.ucl.ac.uk/id/eprint/10094462/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10094462/1/1078-0432.CCR-19-1714.full.pdf
https://discovery.ucl.ac.uk/id/eprint/10094462/

المؤلفون: Śledzińska, A, Vila de Mucha, M, Bergerhoff, K, Hotblack, A, Demane, DF, Ghorani, E, Akarca, AU, Marzolini, MAV, Solomon, I, Vargas, FA, Pule, M, Ono, M, Seddon, B, Kassiotis, G, Ariyan, CE, Korn, T, Marafioti, T, Lord, GM, Stauss, H, Jenner, RG, Peggs, KS, Quezada, SA

المصدر: Immunity , 52 (1) 151-166.e6. (2020)

مصطلحات موضوعية: Blimp-1, CD4-mediated anti-tumor response, IL-2, T-bet, Treg depletion, anti-CTLA-4, cytotoxic CD4(+) T cells, regulatory T cells

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10090149/7/Akarca_1-s2.0-S1074761319305266-main.pdf; https://discovery.ucl.ac.uk/id/eprint/10090149/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10090149/7/Akarca_1-s2.0-S1074761319305266-main.pdf
https://discovery.ucl.ac.uk/id/eprint/10090149/

المؤلفون: Arce Vargas, F, Furness, AJS, Litchfield, K, Joshi, K, Rosenthal, R, Ghorani, E, Solomon, I, Lesko, MH, Ruef, N, Roddie, C, Henry, JY, Spain, L, Ben Aissa, A, Georgiou, A, Wong, YNS, Smith, M, Strauss, D, Hayes, A, Nicol, D, O'Brien, T, Mårtensson, L, Ljungars, A, Teige, I, Frendéus, B, TRACERx Melanoma, TRACERx Renal, TRACERx Lung consortia, Pule, M, Marafioti, T, Gore, M, Larkin, J, Turajlic, S, Swanton, C, Peggs, KS, Quezada, SA

المساهمون: Furness, Andrew, Spain, Lavinia, Smith, Myles

مصطلحات موضوعية: TRACERx Melanoma, TRACERx Renal, TRACERx Lung consortia, Cell Line, Tumor, Animals, Humans, Mice, Melanoma, Receptors, IgG, Antibodies, Monoclonal, Treatment Outcome, Xenograft Model Antitumor Assays, Polymorphism, Single Nucleotide, Female, T-Lymphocytes, Regulatory, CTLA-4 Antigen, Humanized, Antineoplastic Agents, Immunological, Ipilimumab

وصف الملف: Print-Electronic; 663.e4; application/pdf

Relation: Cancer cell, 2018, 33 (4), pp. 649 - 663.e4; https://repository.icr.ac.uk/handle/internal/4004

الاتاحة: https://repository.icr.ac.uk/handle/internal/4004
https://doi.org/10.1016/j.ccell.2018.02.010

المؤلفون: Chakravarthy, A, Furness, A, Joshi, K, Ghorani, E, Ford, K, Ward, MJ, King, EV, Lechner, M, Marafioti, T, Quezada, SA, Thomas, GJ, Feber, A, Fenton, TR

المساهمون: Furness, Andrew, Feber, Andrew

مصطلحات موضوعية: Th1 Cells, Cell Line, Tumor, Macrophages, Humans, Papillomaviridae, Proteome, Reproducibility of Results, Cell Cycle, DNA Methylation, Mutation, Genome, Human, Transcriptome, Squamous Cell Carcinoma of Head and Neck

وصف الملف: Electronic; ?; application/pdf

Relation: Nature communications, 2018, 9 (1), pp. 3220 - ?; https://repository.icr.ac.uk/handle/internal/4005

الاتاحة: https://repository.icr.ac.uk/handle/internal/4005
https://doi.org/10.1038/s41467-018-05570-1

المؤلفون: Wong, YNS, Joshi, K, Khetrapal, P, Ismail, M, Reading, JL, Sunderland, MW, Georgiou, A, Furness, AJS, Ben Aissa, A, Ghorani, E, Oakes, T, Uddin, I, Tan, WS, Feber, A, McGovern, U, Swanton, C, Freeman, A, Marafioti, T, Briggs, TP, Kelly, JD, Powles, T, Peggs, KS, Chain, BM, Linch, MD, Quezada, SA

المساهمون: Feber, Andrew, Furness, Andrew

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Urine, Humans, Lymphocyte Count, Female, Male, Urinary Bladder Neoplasms, Tumor Microenvironment

وصف الملف: Print-Electronic; 2759; application/pdf

Relation: The Journal of experimental medicine, 2018, 215 (11), pp. 2748 - 2759; https://repository.icr.ac.uk/handle/internal/4008

الاتاحة: https://repository.icr.ac.uk/handle/internal/4008
https://doi.org/10.1084/jem.20181003

المؤلفون: Joshi, K, Robert de Massy, M, Ismail, M, Reading, JL, Uddin, I, Woolston, A, Hatipoglu, E, Oakes, T, Rosenthal, R, Peacock, T, Ronel, T, Noursadeghi, M, Turati, V, Furness, AJS, Georgiou, A, Wong, YNS, Ben Aissa, A, Werner Sunderland, M, Jamal-Hanjani, M, Veeriah, S, Birkbak, NJ, Wilson, GA, Hiley, CT, Ghorani, E, Guerra-Assunção, JA, Herrero, J, Enver, T, Hadrup, SR, Hackshaw, A, Peggs, KS, McGranahan, N, Swanton, C, TRACERx Consortium, ., Quezada, SA, Chain, B

المصدر: Nature Medicine , 25 pp. 1549-1559. (2019)

مصطلحات موضوعية: Biological sciences, Immunoediting

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10083835/6/Chain_Spatial%20heterogeneity%20of%20the%20T%20cell%20receptor%20repertoire%20reflects%20the%20mutational%20landscape%20in%20lung%20cancer_AAM.pdf; https://discovery.ucl.ac.uk/id/eprint/10083835/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10083835/6/Chain_Spatial%20heterogeneity%20of%20the%20T%20cell%20receptor%20repertoire%20reflects%20the%20mutational%20landscape%20in%20lung%20cancer_AAM.pdf
https://discovery.ucl.ac.uk/id/eprint/10083835/

المؤلفون: Menares, E, Gálvez-Cancino, F, Cáceres-Morgado, P, Ghorani, E, López, E, Díaz, X, Saavedra-Almarza, J, Figueroa, DA, Roa, E, Quezada, SA, Lladser, A

المصدر: Nature Communications , 10 (1) , Article 4401. (2019)

مصطلحات موضوعية: Dendritic cells, Immunization, Immunological memory, Melanoma, Tumour immunology

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10083091/8/Ghorani_Tissue-resident%20memory%20CD8%E2%81%BA%20T%20cells%20amplify%20anti-tumor%20immunity%20by%20triggering%20antigen%20spreading%20through%20dendritic%20cells_VoR.pdf; https://discovery.ucl.ac.uk/id/eprint/10083091/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10083091/8/Ghorani_Tissue-resident%20memory%20CD8%E2%81%BA%20T%20cells%20amplify%20anti-tumor%20immunity%20by%20triggering%20antigen%20spreading%20through%20dendritic%20cells_VoR.pdf
https://discovery.ucl.ac.uk/id/eprint/10083091/

المؤلفون: Rosenthal, R, Cadieux, EL, Salgado, R, Bakir, MA, Moore, DA, Hiley, CT, Lund, T, Tanić, M, Reading, JL, Joshi, K, Henry, JY, Ghorani, E, Wilson, GA, Birkbak, NJ, Jamal-Hanjani, M, Veeriah, S, Szallasi, Z, Loi, S, Hellmann, MD, Feber, A, Chain, B, Herrero, J, Quezada, SA, Demeulemeester, J, Van Loo, P, Beck, S, McGranahan, N, Swanton, C, TRACERx consortium

المصدر: Nature (2019) (In press).

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10070899/1/Rosenthal_Swanton_2019_wstihfigs.pdf; https://discovery.ucl.ac.uk/id/eprint/10070899/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10070899/1/Rosenthal_Swanton_2019_wstihfigs.pdf
https://discovery.ucl.ac.uk/id/eprint/10070899/

المؤلفون: Ghorani, E., Quartagno, M., Blackhall, F., Gilbert, D.C., O'Brien, M.E.R., Ottensmeier, C.H.H., Pizzo, E., Spicer, J., Williams, A., Badman, P., Milner-Watts, C., Parmar, M.K., Seckl, M.J.

المساهمون: Merck Sharp and Dohme

المصدر: Annals of Oncology ; volume 34, page S845 ; ISSN 0923-7534

الاتاحة: http://dx.doi.org/10.1016/j.annonc.2023.09.2531
https://api.elsevier.com/content/article/PII:S0923753423033689?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0923753423033689?httpAccept=text/plain