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1Academic Journal
المؤلفون: Annemarie Voorberg-van der Wel, Guglielmo Roma, Devendra Kumar Gupta, Sven Schuierer, Florian Nigsch, Walter Carbone, Anne-Marie Zeeman, Boon Heng Lee, Sam O Hofman, Bart W Faber, Judith Knehr, Erica Pasini, Bernd Kinzel, Pablo Bifani, Ghislain M C Bonamy, Tewis Bouwmeester, Clemens H M Kocken, Thierry Tidiane Diagana
المصدر: eLife, Vol 6 (2017)
مصطلحات موضوعية: malaria, liver stages, hypnozoites, transcriptomics, plasmodium, Plasmodium cynomolgi, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2
المؤلفون: Haoying Xu, Wei Lin Sandra Sim, Cheah Chen Seh, Feng Wang, Thierry T. Diagana, Wai Ling Chan, Jae-Geun Song, Kah Fei Wan, Bin Zou, Ghislain M. C. Bonamy, David Beer, David T. Barkan, Min Li, Stephanie A. Moquin, Francesca Blasco, Suresh B. Lakshminarayana, Jin Zhang, Oliver Simon, Vito G. Sasseville, Craig W. Day, Qing-Yin Wang, Chandrassegar Saravanan, Katherine Chan, Fumiaki Yokokawa, Bryan K. S. Yeung, Ratna Karuna, Hui-Quan Yeo, Colin Osborne, Christopher Sarko, Pei Yong Shi, Hongping Dong, Mei Ding, Siew Pheng Lim, Yen Liang Chen, Feng Gu, Cyrille Kounde, Gang Wang, Siyan Lu, Wei Liu
المصدر: Science Translational Medicine. 13
مصطلحات موضوعية: 0301 basic medicine, biology, medicine.drug_class, business.industry, 030106 microbiology, Viremia, General Medicine, Dengue virus, Pharmacology, medicine.disease_cause, medicine.disease, biology.organism_classification, Dengue fever, Bioavailability, 03 medical and health sciences, Flavivirus, 030104 developmental biology, Pharmacokinetics, medicine, Potency, Antiviral drug, business
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3Academic Journal
المؤلفون: Sungeun Kim, Anna Dubrovska, Richard J Salamone, John R Walker, Kathryn B Grandinetti, Ghislain M C Bonamy, Anthony P Orth, Jimmy Elliott, Diana Graus Porta, Carlos Garcia-Echeverria, Venkateshwar A Reddy
المصدر: PLoS ONE, Vol 8, Iss 1, p e51671 (2013)
وصف الملف: electronic resource
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المؤلفون: Xavier, Pivot, M A, Georgievich, Volodymyr, Shamrai, Giorgi, Dzagnidze, Hwoei Fen, Soo Hoo, Viriya, Kaewkangsadan, Fausto, Petrelli, Cristian, Villanueva, Lipatov O, Nikolaevich, Jocelyn, Hii, Jamie, Kim, Sumita, Pradhan, Litha, Jaison, Peggy, Feyaerts, Leonard, Kaufman, Marie-Paule, Derde, Ghislain M C, Bonamy, Filip, Deforce, David G, Cox
المصدر: JAMA Oncol
مصطلحات موضوعية: Adult, Aged, 80 and over, Cancer Research, Receptor, ErbB-2, Correction, Antineoplastic Agents, Breast Neoplasms, Middle Aged, Trastuzumab, Neoadjuvant Therapy, Oncology, Humans, Female, Aged
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5
المؤلفون: Alex Chao, Boon Heng Lee, Kah Fei Wan, David Beer, Peter Gedeck, Thierry T. Diagana, Jeremy J. Selva, Bin Zou, Ujjini H. Manjunatha, Ghislain M. C. Bonamy
المصدر: ACS Infectious Diseases. 4:635-645
مصطلحات موضوعية: Cryptosporidium parvum, 0301 basic medicine, biology, High-throughput screening, Phenotypic screening, 030106 microbiology, Antiprotozoal Agents, Drug Evaluation, Preclinical, Epithelial Cells, Cryptosporidium, Nitazoxanide, biology.organism_classification, Virology, In vitro, Cell Line, 03 medical and health sciences, 030104 developmental biology, Infectious Diseases, parasitic diseases, medicine, Humans, Cryptosporidium hominis, medicine.drug, Cytopathic effect
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6
المؤلفون: Chia Min Lee, Kah Fei Wan, Ralph Riedl, Marco Janoschke, Ghislain M. C. Bonamy, Tewis Bouwmeester, Olaf Galuba, Hongping Dong, Philippe Mathys, Tim Schuhmann, David Estoppey, Martin Spiess, Carsten Russ, Dominic Hoepfner, Ireos Filipuzzi, Boon Heng Lee, Gregory McAllister, Thomas Aust
المصدر: Cell Reports, Vol 19, Iss 3, Pp 451-460 (2017)
مصطلحات موضوعية: 0301 basic medicine, Signal peptide, Protein subunit, 030106 microbiology, Saccharomyces cerevisiae, Dengue virus, medicine.disease_cause, Virus Replication, General Biochemistry, Genetics and Molecular Biology, Zika virus, 03 medical and health sciences, Lipopeptides, Viral Proteins, medicine, CRISPR, Humans, Flavivirus Infections, lcsh:QH301-705.5, Signal peptidase, Biological Products, biology, Cas9, Genome, Human, Serine Endopeptidases, Membrane Proteins, Genomics, Zika Virus, Dengue Virus, biology.organism_classification, HCT116 Cells, Virology, Protein Subunits, 030104 developmental biology, lcsh:Biology (General), Gene Knockdown Techniques, CRISPR-Cas Systems
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7
المؤلفون: Hongping Dong, Bryan K. S. Yeung, Ratna Karuna, Bin Zou, Trixie Wagner, Hui-Quan Yeo, Cyrille Kounde, Oliver Simon, Kah Fei Wan, Qing-Yin Wang, Ghislain M. C. Bonamy, Fumiaki Yokokawa, Ina Dix
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:1385-1389
مصطلحات موضوعية: 0301 basic medicine, Scaffold, High-throughput screening, Clinical Biochemistry, Pharmaceutical Science, Dengue virus, medicine.disease_cause, Antiviral Agents, 01 natural sciences, Biochemistry, Piperazines, Virus, Cell Line, Pyrrolopiperazinone, Dengue fever, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, medicine, Humans, Molecular Biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Dengue Virus, medicine.disease, Phenotype, Virology, High-Throughput Screening Assays, 0104 chemical sciences, 030104 developmental biology, Molecular Medicine
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8
المؤلفون: Clemens H. M. Kocken, Judith Knehr, Devendra Kumar Gupta, Ghislain M. C. Bonamy, Bart W. Faber, Boon Heng Lee, Sam O. Hofman, Erica M. Pasini, Sven Schuierer, Florian Nigsch, Tewis Bouwmeester, Walter Carbone, Annemarie Voorberg-van der Wel, Thierry T. Diagana, Guglielmo Roma, Bernd Kinzel, Anne-Marie Zeeman, Pablo Bifani
المصدر: eLife, Vol 6 (2017)
مصطلحات موضوعية: 0301 basic medicine, Genome integrity, QH301-705.5, Science, malaria, Biology, General Biochemistry, Genetics and Molecular Biology, Transcriptome, 03 medical and health sciences, transcriptomics, Plasmodium cynomolgi, parasitic diseases, medicine, Parasite hosting, Biology (General), liver stages, General Immunology and Microbiology, Drug discovery, General Neuroscience, General Medicine, medicine.disease, Virology, 3. Good health, Gene expression profiling, 030104 developmental biology, hypnozoites, plasmodium, Infectious disease (medical specialty), Medicine, Malaria
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المؤلفون: Florian Nigsch, Devendra Kumar Gupta, Thierry T. Diagana, Bart W. Faber, Pablo Bifani, Judith Knehr, Sven Schuierer, Boon Heng Lee, Walter Carbone, Guglielmo Roma, Anne-Marie Zeeman, Tewis Bouwmeester, Ghislain M. C. Bonamy, Sam O. Hofman, Annemarie Voorberg-van der Wel, Erica M. Pasini, Clemens H. M. Kocken, Bernd Kinzel
مصطلحات موضوعية: 0301 basic medicine, Transcriptome, 03 medical and health sciences, 030104 developmental biology, Plasmodium cynomolgi, medicine, Parasite hosting, Biology, medicine.disease, Virology, Malaria
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المؤلفون: Bruce Russell, Bryan K. S. Yeung, David A. Fidock, François Nosten, Michael D. Edstein, Pablo Bifani, Marina Chavchich, Judith Straimer, Jeremy J. Selva, Thierry T. Diagana, M. Yi-Xiu Lim, Christophe Bodenreider, X. Ang, Ghislain M. C. Bonamy, Laurent Dembele
المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reportsمصطلحات موضوعية: Drug, media_common.quotation_subject, medicine.medical_treatment, Science, Population, Plasmodium falciparum, Drug Resistance, Dihydroartemisinin, Pharmacology, Plasmodium, Article, 03 medical and health sciences, Antimalarials, parasitic diseases, medicine, Animals, Humans, Artemisinin, Malaria, Falciparum, education, 030304 developmental biology, media_common, 0303 health sciences, education.field_of_study, Multidisciplinary, biology, 030306 microbiology, Cell Cycle Checkpoints, medicine.disease, biology.organism_classification, Artemisinins, 3. Good health, Pyrazines, Dormancy, Medicine, Malaria, medicine.drug
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المؤلفون: Marjo Götte, Danilo Guerini, Ansgar Schuffenhauer, Daniela Siebert, Marion Kamke, Ursula Bodendorf, Yvonne Ibig-Rehm, Daniela Gabriel, Xian Zhang, Dan Beisner, Ghislain M. C. Bonamy
المصدر: SLAS discovery : advancing life sciences RD. 22(9)
مصطلحات موضوعية: 0301 basic medicine, Signal peptide, biology, Intramembrane protease, Drug discovery, Multiparametric Analysis, Intracellular protein, Drug target, Computational biology, 01 natural sciences, Biochemistry, Molecular biology, 0104 chemical sciences, Analytical Chemistry, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Cytosol, 030104 developmental biology, High-content screening, biology.protein, Molecular Medicine, Biotechnology
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المؤلفون: Christina Scheel, Zsuzsanna Varga, Michael B. Stadler, Mohamed Bentires-Alj, Sungeun Kim, Daniela Kaup, Kirsten D. Mertz, Adrian Britschgi, Shany Koren, Heike Brinkhaus, Alexandra Vissieres, Ghislain M. C. Bonamy, Joana Pinto Couto, Hans Voshol, Tim Roloff, Stephan Duss, Loren Miraglia, Duvini De Silva, Cédric Leroy, Venkateshwar A. Reddy, Anthony P. Orth
المساهمون: University of Zurich, Bentires-Alj, Mohamed
المصدر: Nature
Nature 541, 541-545 (2017)مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, medicine.medical_specialty, Ubiquitin-Protein Ligases, Cellular differentiation, 610 Medicine & health, Cell fate determination, Biology, Protein Serine-Threonine Kinases, Article, 03 medical and health sciences, Breast cancer, 10049 Institute of Pathology and Molecular Pathology, Internal medicine, medicine, Humans, Cell Lineage, Genes, Tumor Suppressor, Hippo Signaling Pathway, Breast, Progenitor cell, skin and connective tissue diseases, Transcription factor, Cells, Cultured, Adaptor Proteins, Signal Transducing, 1000 Multidisciplinary, Hippo signaling pathway, Multidisciplinary, Ubiquitin, Tumor Suppressor Proteins, Myoepithelial cell, Estrogen Receptor alpha, YAP-Signaling Proteins, Cell Differentiation, Phosphoproteins, medicine.disease, Research Highlight, 3. Good health, Cell biology, 030104 developmental biology, Endocrinology, Proteolysis, Female, Stem cell, Carrier Proteins, Transcription Factors, Signal Transduction
وصف الملف: application/pdf; Britschgi_nature20829_2017.pdf - application/pdf
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المؤلفون: Thierry T. Diagana, Suresh B. Lakshminarayana, Susan Noh, Francesca Blasco, Carrie F. Brooks, Jennifer A. Zambriski, Laura B. Goodman, Gu Feng, Sumiti Vinayak, Gillian T. Herbert, Peter Gedeck, Lijun Zhang, Jayesh Tandel, Siau H. Lim, Christian G. Noble, F. Joel Leong, Alex Chao, Juergen Wagner, Bin Zou, Boris Striepen, Tracy Sy, Ravinder Reddy Kondreddi, Christophe Bodenreider, Ujjini H. Manjunatha, Ghislain M. C. Bonamy, Adam Sateriale
المصدر: Nature
مصطلحات موضوعية: 0301 basic medicine, Male, Pyridines, Cryptosporidiosis, Cryptosporidium, Communicable Diseases, Article, Microbiology, 03 medical and health sciences, Immunocompromised Host, Interferon-gamma, Mice, Cell Line, Tumor, parasitic diseases, Pyrazolopyridine, medicine, Animals, Humans, Interferon gamma, Rats, Wistar, 1-Phosphatidylinositol 4-Kinase, Mice, Knockout, Multidisciplinary, biology, Kinase, Drug discovery, business.industry, biology.organism_classification, Antiparasitic agent, Virology, 3. Good health, Rats, Disease Models, Animal, 030104 developmental biology, Cryptosporidium parvum, Animals, Newborn, Pyrazoles, Cattle, Female, business, Cryptosporidium hominis, medicine.drug
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14
المؤلفون: Pablo Bifani, Elizabeth A. Winzeler, Victoria C. Corey, David A. Fidock, Christin Reimer, Benoit Malleret, Bianca F Bf Tjahjadi, Bee Huat Tan, Thierry T. Diagana, Marcus C. S. Lee, Laurent Rénia, Bryan K. S. Yeung, Paul Chi-Lui Pc Ho, Liting L. Lim, René Wintjens, Michelle Yi-Xiu Lim, Eric D. Chow, Peter Gedeck, Marie Nachon, Gregory G. LaMonte, Adeline C. Y. Chua, Ghislain M. C. Bonamy
المصدر: Nature microbiology
مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), 030106 microbiology, Immunology, Mutant, Drug resistance, Bioinformatics, Applied Microbiology and Biotechnology, Microbiology, Article, 03 medical and health sciences, parasitic diseases, Genetics, Medicine, CRISPR, Plasmodium berghei, Gene, biology, business.industry, Plasmodium falciparum, Transporter, Cell Biology, biology.organism_classification, 3. Good health, Multiple drug resistance, 030104 developmental biology, Biochemistry, business
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المؤلفون: Jianing Wang, Peter G. Schultz, Peng-Yu Yang, Carolina N. Turk, Richard G. Brusch, Danling Wang, Shelly Meeusen, Ghislain M. C. Bonamy
المصدر: Angewandte Chemie. 124:9436-9439
مصطلحات موضوعية: Cell Survival, MFN2, Mitochondrion, Mitochondrial Dynamics, Catalysis, Cell Line, GTP Phosphohydrolases, Mice, Organelle, Hydrocarbons, Chlorinated, medicine, Animals, Humans, MFN1, Microscopy, Confocal, ATP synthase, biology, Chemistry, Hydrazones, General Chemistry, General Medicine, Fibroblasts, Mitochondrial Proton-Translocating ATPases, medicine.disease, Molecular biology, Mitochondria, Cell biology, Oxidative Phosphorylation Coupling Factors, mitochondrial fusion, Apoptosis, biology.protein, Optic Atrophy 1
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المؤلفون: Ismael Secundino, Loren Miraglia, Paul D. De Jesus, Ana Fernandez-Sesma, Quy T. Nguyen, Irene Ramos, Chih-yuan Chiang, Yingyao Zhou, Ghislain M. C. Bonamy, Genevieve Welch, Victor Nizet, Ana M. Maestre, Anthony P. Orth, Amanda M. Opaluch, Gregory M. Barton, Alex Engel, Sumit K. Chanda
المصدر: Cell Host & Microbe. 11:306-318
مصطلحات موضوعية: Cancer Research, Support Vector Machine, Endocytic cycle, Chick Embryo, Endosomes, Biology, Models, Biological, Microbiology, Article, 03 medical and health sciences, 0302 clinical medicine, RNA interference, Immunology and Microbiology(all), Virology, Animals, Humans, Computer Simulation, Gene Regulatory Networks, Molecular Biology, 030304 developmental biology, 0303 health sciences, Innate immune system, Endosomal Sorting Complexes Required for Transport, Gene Expression Profiling, Intracellular Signaling Peptides and Proteins, Pattern recognition receptor, TLR7, Phosphoproteins, Endolysosome, Immunity, Innate, Cell biology, Chromatin, Protein Transport, HEK293 Cells, Toll-Like Receptor 7, Gene Knockdown Techniques, Toll-Like Receptor 9, 030220 oncology & carcinogenesis, Myeloid Differentiation Factor 88, RNA Interference, Parasitology, Signal transduction, Signal Transduction
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المؤلفون: Neekesh V. Dharia, Case W. McNamara, Elizabeth A. Winzeler, Badry Bursulaya, Selina Bopp, Susan McCormack, David Plouffe, Nobutaka Kato, Tae-gyu Nam, Akhil B. Vaidya, Peter G. Schultz, Ghislain M. C. Bonamy, Stephan Meister, Hangjun Ke
المصدر: ACS Chemical Biology
مصطلحات موضوعية: Models, Molecular, Cytochrome, 030231 tropical medicine, Plasmodium falciparum, Pharmacology, Crystallography, X-Ray, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, Mice, Structure-Activity Relationship, 0302 clinical medicine, Parasitic Sensitivity Tests, Drug Resistance, Fungal, Drug Discovery, medicine, Animals, Decoquinate, Humans, Gene, 030304 developmental biology, 0303 health sciences, Mice, Inbred ICR, biology, Molecular Structure, Cytochrome b, Fungal genetics, General Medicine, Articles, Cytochromes b, biology.organism_classification, Molecular biology, 3. Good health, chemistry, biology.protein, Dihydroorotate dehydrogenase, Molecular Medicine, Female, Atovaquone, medicine.drug
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المؤلفون: Estelle Glory-Afshar, Daniel R. Rines, Ghislain M. C. Bonamy, Robert F. Murphy, Sumit K. Chanda, Tao Peng
المصدر: Proceedings of the National Academy of Sciences. 107:2944-2949
مصطلحات موضوعية: Proteomics, Multidisciplinary, Intracellular Space, Colocalization, Image processing, Biological Sciences, Biology, Fluorescence, Cell biology, Transport protein, Protein Transport, Artificial Intelligence, Organelle, Image Processing, Computer-Assisted, Compartment (pharmacokinetics), Biological system, Algorithms, Cellular compartment, Fluorescent Dyes
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المؤلفون: Anna Dubrovska, Sungeun Kim, Anthony P. Orth, Ghislain M. C. Bonamy, Kathryn B. Grandinetti, Richard J. Salamone, Jimmy Elliott, Diana Graus Porta, John R. Walker, Venkateshwar A. Reddy, Carlos Garcia-Echeverria
المصدر: PLoS ONE, Vol 8, Iss 1, p e51671 (2013)
PLoS ONEمصطلحات موضوعية: Mouse, Cellular differentiation, Tumor Physiology, Cancer Treatment, Cell Culture Techniques, Gene Expression, lcsh:Medicine, Fibroblast growth factor, Mice, Mice, Inbred NOD, Drug Discovery, Molecular Cell Biology, Basic Cancer Research, Breast Tumors, lcsh:Science, education.field_of_study, Gene knockdown, Multidisciplinary, Stem Cells, Cancer Risk Factors, Integrin beta1, Obstetrics and Gynecology, Cell Differentiation, Animal Models, Signaling in Selected Disciplines, Flow Cytometry, Gene Expression Regulation, Neoplastic, Oncology, Neoplastic Stem Cells, Medicine, Female, Cellular Types, Research Article, Biotechnology, Signal Transduction, congenital, hereditary, and neonatal diseases and abnormalities, Tics, Population, Genetic Causes of Cancer, Breast Neoplasms, Mammary Neoplasms, Animal, Biology, Breast cancer, Model Organisms, Breast Cancer, mental disorders, medicine, Genetics, Animals, Humans, Kinase activity, Receptor, Fibroblast Growth Factor, Type 2, education, Cell Proliferation, Oncogenic Signaling, Cell growth, Gene Expression Profiling, lcsh:R, Cancers and Neoplasms, CD24 Antigen, Chemotherapy and Drug Treatment, medicine.disease, nervous system diseases, body regions, Microscopy, Fluorescence, Immunology, Cancer research, lcsh:Q, Gene Function, human activities, Neoplasm Transplantation
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المؤلفون: Ghislain M. C. Bonamy, Michael B. Stadler, Loren Miraglia, Anthony P. Orth, Mohamed Bentires-Alj, Sungeun Kim, Joana Pinto Couto, Duvini De Silva, Adrian Britschgi, Stephan Duss, Heike Brinkhaus, Venkateshwar A. Reddy
المصدر: Cancer Research. 76:3305-3305
مصطلحات موضوعية: Cancer Research, Hippo signaling pathway, Oncology, Kinase, Biology, Cell fate determination, Human breast, Cell biology