المؤلفون: Swan, Anna L, Schütt, Christine, Rozman, Jan, del Mar Muñiz Moreno, Maria, Brandmaier, Stefan, Simon, Michelle, Leuchtenberger, Stefanie, Griffiths, Mark, Brommage, Robert, Keskivali-Bond, Piia, Grallert, Harald, Werner, Thomas, Teperino, Raffaele, Becker, Lore, Miller, Gregor, Moshiri, Ala, Seavitt, John R, Cissell, Derek D, Meehan, Terrence F, Acar, Elif F, Lelliott, Christopher J, Flenniken, Ann M, Champy, Marie-France, Sorg, Tania, Ayadi, Abdel, Braun, Robert E, Cater, Heather, Dickinson, Mary E, Flicek, Paul, Gallegos, Juan, Ghirardello, Elena J, Heaney, Jason D, Jacquot, Sylvie, Lally, Connor, Logan, John G, Teboul, Lydia, Mason, Jeremy, Spielmann, Nadine, McKerlie, Colin, Murray, Stephen A, Nutter, Lauryl MJ, Odfalk, Kristian F, Parkinson, Helen, Prochazka, Jan, Reynolds, Corey L, Selloum, Mohammed, Spoutil, Frantisek, Svenson, Karen L, Vales, Taylor S, Wells, Sara E, White, Jacqueline K, Sedlacek, Radislav, Wurst, Wolfgang, Lloyd, KC Kent, Croucher, Peter I, Fuchs, Helmut, Williams, Graham R, Bassett, JH Duncan, Gailus-Durner, Valerie, Herault, Yann, Mallon, Ann-Marie, Brown, Steve DM, Mayer-Kuckuk, Philipp, Hrabe de Angelis, Martin

المصدر: PLOS Genetics. 16(12)

مصطلحات موضوعية: Biological Sciences, Genetics, Aging, Osteoporosis, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Musculoskeletal, Animals, Bone Density, Female, Gene Expression Regulation, Gene Ontology, Genetic Pleiotropy, Genome-Wide Association Study, Genotype, Male, Mice, Mice, Transgenic, Mutation, Osteoblasts, Osteoclasts, Phenotype, Promoter Regions, Genetic, Protein Interaction Maps, Sex Characteristics, Transcriptome, IMPC Consortium, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6k44398j
https://escholarship.org/content/qt6k44398j/qt6k44398j.pdf

المؤلفون: Ruggiero, Carmen, Durand, Nelly, Jarjat, Marielle, Barhanin, Jacques, Ghirardello, Elena, J, Dack, Michael, R G, Williams, Graham, R, Bassett, J, H Duncan, Lalli, Enzo

المساهمون: Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Laboratoire de PhysioMédecine Moléculaire (LP2M), Imperial College London, Fondation Jérôme Lejeune #1944, Fondation ARC Project PJA 20191209289, ANR-15-CE14-0017,LOCALDO,Mécanismes du contrôle LOCal de la production de l'ALDOstérone dans la glande surrénale et leur importance dans la pathogénèse de l'hyperaldosteronisme primaire(2015)

المصدر: ISSN: 2768-0622 ; Clinical and Translational Discovery ; https://hal.science/hal-03838818 ; Clinical and Translational Discovery, 2022, 2 (3), pp.e113. ⟨10.1002/ctd2.113⟩.

مصطلحات موضوعية: bone, peptides, Wnt signalling, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

Relation: hal-03838818; https://hal.science/hal-03838818; https://hal.science/hal-03838818/document; https://hal.science/hal-03838818/file/Clinical%20and%20Translational%20Dis%20-%202022%20-%20Ruggiero%20-%20The%20secreted%20protein%20augurin%20is%20a%20novel%20modulator%20of%20canonical%20Wnt_compressed.pdf

الاتاحة: https://hal.science/hal-03838818
https://hal.science/hal-03838818/document
https://hal.science/hal-03838818/file/Clinical%20and%20Translational%20Dis%20-%202022%20-%20Ruggiero%20-%20The%20secreted%20protein%20augurin%20is%20a%20novel%20modulator%20of%20canonical%20Wnt_compressed.pdf
https://doi.org/10.1002/ctd2.113

المؤلفون: Butterfield, Natalie C, Curry, Katherine F, Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S, Adoum, Anne-Tounsia, Leitch, Victoria D, Logan, John G, Waung, Julian A, Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E, Wilkinson, J Mark, McAninch, Elizabeth A, Vancollie, Valerie E, Kussy, Fiona, White, Jacqueline K, Lelliott, Christopher J, Adams, David J, Jacques, Richard, Bianco, Antonio C, Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I, Williams, Graham R, Bassett, JH Duncan

وصف الملف: Electronic; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/341479

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/341479
https://doi.org/10.17863/CAM.88906

المؤلفون: Youlten, Scott E., Kemp, John P., Logan, John G., Ghirardello, Elena J., Sergio, Claudio M., Dack, Michael R.G., Guilfoyle, Siobhan E., Leitch, Victoria D., Butterfield, Natalie C., Komla-Ebri, Davide, Chai, Ryan C., Corr, Alexander P., Smith, James T., Mohanty, Sindhu T., Morris, John A., McDonald, Michelle M., Quinn, Julian M.W., McGlade, Amelia R., Bartonicek, Nenad, Jansson, Matt, Hatzikotoulas, Konstantinos, Irving, Melita D., Beleza-Meireles, Ana, Rivadeneira, Fernando, Duncan, Emma, Richards, J. Brent, Adams, David J., Lelliott, Christopher J., Brink, Robert, Phan, Tri Giang, Eisman, John A., Evans, David M., Zeggini, Eleftheria, Baldock, Paul A., Bassett, J. H.Duncan, Williams, Graham R., Croucher, Peter I.

المصدر: Youlten , S E , Kemp , J P , Logan , J G , Ghirardello , E J , Sergio , C M , Dack , M R G , Guilfoyle , S E , Leitch , V D , Butterfield , N C , Komla-Ebri , D , Chai , R C , Corr , A P , Smith , J T , Mohanty , S T , Morris , J A , McDonald , M M , Quinn , J M W , McGlade , A R , Bartonicek , N , Jansson , M , ....

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الاتاحة: https://pure.eur.nl/en/publications/f586a47b-51a6-4d98-bdb2-36b67789ec89
https://doi.org/10.1038/s41467-021-22517-1
http://www.scopus.com/inward/record.url?scp=85105379914&partnerID=8YFLogxK

المؤلفون: Youlten, Scott E, Kemp, John P, Logan, John G, Ghirardello, Elena J, Sergio, Claudio M, Dack, Michael RG, Guilfoyle, Siobhan E, Leitch, Victoria D, Butterfield, Natalie C, Komla-Ebri, Davide, Chai, Ryan C, Corr, Alexander P, Smith, James T, Mohanty, Sindhu T, Morris, John A, McDonald, Michelle M, Quinn, Julian MW, McGlade, Amelia R, Bartonicek, Nenad, Jansson, Matt, Hatzikotoulas, Konstantinos, Irving, Melita D, Beleza-Meireles, Ana, Rivadeneira, Fernando, Duncan, Emma, Richards, J Brent, Adams, David J, Lelliott, Christopher J, Brink, Robert, Phan, Tri Giang, Eisman, John A, Evans, David M, Zeggini, Eleftheria, Baldock, Paul A, Bassett, JH Duncan, Williams, Graham R, Croucher, Peter I

مصطلحات موضوعية: Age Factors, Animals, Bone Diseases, Bone and Bones, Computational Biology, Female, Homeostasis, Humans, Male, Mice, Knockout, Osteocytes, Osteoporosis, Sequence Analysis, RNA, Sex Factors, Transcriptome

وصف الملف: Electronic; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/323516

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/323516
https://doi.org/10.17863/CAM.70974

المؤلفون: Butterfield, Natalie C, Curry, Katherine F, Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S, Adoum, Anne-Tounsia, Leitch, Victoria D, Logan, John G, Waung, Julian A, Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E, Wilkinson, J Mark, McAninch, Elizabeth A, Vancollie, Valerie E, Kussy, Fiona, White, Jacqueline K, Lelliott, Christopher J, Adams, David J, Jacques, Richard, Bianco, Antonio C, Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I, Williams, Graham R, Bassett, JH Duncan

مصطلحات موضوعية: Animals, Bone and Bones, CRISPR-Cas Systems, Cartilage, Clustered Regularly Interspaced Short Palindromic Repeats, Disease Models, Animal, Drug Discovery, Gene Editing, Genetic Association Studies, Genetic Predisposition to Disease, Gonadotropin-Releasing Hormone, Iodide Peroxidase, Mice, Knockout, Osteoarthritis, Paired Box Transcription Factors, Phenotype, Iodothyronine Deiodinase Type II

وصف الملف: Electronic; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/317177

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/317177
https://doi.org/10.17863/CAM.64289

المؤلفون: Butterfield, Natalie C., Curry, Katherine F., Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S., Adoum, Anne-Tounsia, Leitch, Victoria D., Logan, John G., Waung, Julian A., Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E., Wilkinson, J. Mark, McAninch, Elizabeth A., Vancollie, Valerie E., Kussy, Fiona, White, Jacqueline K., Lelliott, Christopher J., Adams, David J., Jacques, Richard, Bianco, Antonio C., Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan

المساهمون: Wellcome Trust, Mrs. Janice Gibson and the Ernest Heine Family Foundation, EC | Horizon 2020 Framework Programme

المصدر: Nature Communications ; volume 12, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-020-20761-5
https://www.nature.com/articles/s41467-020-20761-5.pdf
https://www.nature.com/articles/s41467-020-20761-5

المؤلفون: Butterfield, Natalie C., Curry, Katherine F., Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S., Adoum, Anne-Tounsia, Leitch, Victoria D., Logan, John G., Waung, Julian A., Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E., Wilkinson, J. Mark, McAninch, Elizabeth A., Vancollie, Valerie E., Kussy, Fiona, White, Jacqueline K., Lelliott, Christopher J., Adams, David J., Jacques, Richard, Bianco, Antonio C., Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan

المصدر: Nature Communications ; volume 12, issue 1 ; ISSN 2041-1723

الاتاحة: https://doi.org/10.1038/s41467-021-23768-8
https://www.nature.com/articles/s41467-021-23768-8.pdf
https://www.nature.com/articles/s41467-021-23768-8

المؤلفون: Swan, Anna L., Schütt, C. (Christine), Rozman, J. (Jan), Muñiz Moreno, M. (Maria del Mar), Brandmaier, S. (Stefan), Simon, M. (Michelle), Leuchtenberger, S. (Stefanie), Griffiths, M. (Mark), Brommage, R. (Robert), Keskivali-Bond, P. (Piia), Grallert, H. (Harald), Werner, T. (Thomas), Teperino, R. (Raffaele), Becker, L. (Lore), Miller, G. (Gregor), Moshiri, A. (Ala), Seavitt, John R., Cissell, Derek D., Meehan, Terrence F., Acar, Elif F., Lelliott, Christopher J., Flenniken, Ann M., Champy, M. (Marie-France), Sorg, T. (Tania), Ayadi, A. (Abdelkader), Braun, Robert E., Cater, H. (Heather), Dickinson, Mary E., Flicek, P. (Paul), Gallegos, J. (Juan), Ghirardello, Elena J., Heaney, Jason D., Jacquot, S. (Sylvie), Lally, C. (Connor), Logan, John G., Teboul, L. (Lydia), Mason, J. (Jeremy), Spielmann, N. (Nadine), McKerlie, C. (Colin), Murray, Stephen A., Nutter, Lauryl M. J., Odfalk, Kristian F., Parkinson, H. (Helen), Prochazka, J. (Jan), Reynolds, Corey L., Selloum, M. (Mohammed), Spoutil, F. (Frantisek), Svenson, Karen L., Vales, Taylor S., Wells, Sara E., White, Jacqueline K., Sedlacek, R. (Radislav), Wurst, W. (Wolfgang), Lloyd, K. C. Kent, Croucher, Peter I., Fuchs, H. (Helmut), Williams, Graham R., Bassett, J. H. Duncan, Gailus-Durner, V. (Valerie), Herault, Y. (Yann), Mallon, A. (Ann-Marie), Brown, Steve D. M., Mayer-Kuckuk, P. (Philipp), Hrabe de Angelis, M. (Martin)

مصطلحات موضوعية: Sciences du Vivant [q-bio]/Médecine humaine et pathologie, Sciences du Vivant [q-bio]/Biologie animale

الاتاحة: https://doi.org/10.1371/journal.pgen.1009190

المؤلفون: Komla-Ebri, Davide, Pollard, Andrea S., Sparkes, Penny C., Ghirardello, Elena J., Gogakos, Apostolos, Logan, John G., Williams, Graham R., Bassett, J.H. Duncan

المصدر: Bone Reports ; volume 13, page 100646 ; ISSN 2352-1872

الاتاحة: http://dx.doi.org/10.1016/j.bonr.2020.100646
https://api.elsevier.com/content/article/PII:S235218722030406X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S235218722030406X?httpAccept=text/plain

المؤلفون: Morris, John A, Kemp, John P., Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan C., Vulpescu, Nicholas A., Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu T., Sergio, C. Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee Lee, Vijay, Jinchu, Simon, Marie Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne Tounsia, Mannan, Naila S., Komla-Ebri, Davide S.K., Pollard, Andrea S., Dewhurst, Hannah F., Hassall, Thomas A.D., Beltejar, Michael John G., Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., McCreight, Jennifer C., Huber, Karen E., Litterman, Nadia K., McIntyre, Matthew H., Mountain, Joanna L., Wilson, Catherine H., Cooper, Cyrus, Tobias, Jonathan H., Gregson, Celia L., Adams, David J., Evans, David M.

المصدر: the 23 and Me Research Team , Morris , J A , Kemp , J P , Youlten , S E , Laurent , L , Logan , J G , Chai , R C , Vulpescu , N A , Forgetta , V , Kleinman , A , Mohanty , S T , Sergio , C M , Quinn , J , Nguyen-Yamamoto , L , Luco , A L , Vijay , J , Simon , M M , Pramatarova , A , Medina-Gomez , C , Trajanoska , K , Ghirardello , E J , Butterfield ....

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/1983/5ae4f474-7885-469a-b8f6-a86a22b032bd
https://research-information.bris.ac.uk/en/publications/5ae4f474-7885-469a-b8f6-a86a22b032bd
https://doi.org/10.1038/s41588-018-0302-x
https://research-information.bris.ac.uk/ws/files/178292453/Morrisetal2018.NatGen.Manuscript.pdf
http://www.scopus.com/inward/record.url?scp=85059469185&partnerID=8YFLogxK

المؤلفون: Kemp, John P, Medina-Gomez, Carolina, Forgetta, Vincenzo, Warrington, Nicole M, Youlten, Scott E, Zheng, Jie, Gregson, Celia L, Grundberg, Elin, Trajanoska, Katerina, Logan, John G, Pollard, Andrea S, Sparkes, Penny C, Ghirardello, Elena J, Leitch, Victoria D, Butterfield, Natalie C, Komla-Ebri, Davide, Adoum, Anne-Tounsia, Curry, Katharine F, White, Jacqueline K, Kussy, Fiona, Greenlaw, Keelin M, Xu, Changjiang, Harvey, Nicholas C, Cooper, Cyrus, Greenwood, Celia M T, Maurano, Matthew T, Kaptoge, Stephen, Rivadeneira, Fernando, Tobias, Jonathan H, Croucher, Peter I, Ackert-Bicknell, Cheryl L, Bassett, J H Duncan, Richards, J Brent, Evans, David M

المصدر: Kemp , J P , Medina-Gomez , C , Forgetta , V , Warrington , N M , Youlten , S E , Zheng , J , Gregson , C L , Grundberg , E , Trajanoska , K , Logan , J G , Pollard , A S , Sparkes , P C , Ghirardello , E J , Leitch , V D , Butterfield , N C , Komla-Ebri , D , Adoum , A-T , Curry , K F , White , J K , Kussy , F , Greenlaw , K M , Xu , ....

مصطلحات موضوعية: Bone mineral density, Genome-wide association, GPC6, Osteoporosis, UK Biobank, Ultrasound

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/1983/3add3904-73fa-4e06-957d-a45a9d8baea1
https://research-information.bris.ac.uk/en/publications/3add3904-73fa-4e06-957d-a45a9d8baea1
https://doi.org/10.1038/ng.3949
https://research-information.bris.ac.uk/ws/files/124277384/NG_A45024R_Manuscript.pdf
https://research-information.bris.ac.uk/ws/files/124500297/Supplementary_information_PDF.pdf
https://research-information.bris.ac.uk/ws/files/124500287/Figure_1_PDF.pdf
https://research-information.bris.ac.uk/ws/files/124500289/Figure_2_PDF.pdf
https://research-information.bris.ac.uk/ws/files/124500291/Figure_3_PDF.pdf
https://research-information.bris.ac.uk/ws/files/124500293/Figure_4_PDF.pdf
https://research-information.bris.ac.uk/ws/files/124500295/Figure_5_PDF.pdf

المؤلفون: Morris, John, Kemp, John, Youlten, Scott, Logan, John, Chai, Ryan, Vulpescu, Nicholas, Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu, Sergio, Marcelo, Medina-Gomez, Carolina, Trajanoska, Katerina, Quinn, Julian, Ghirardello, Elena, Butterfield, Natalie, Curry, Katharine, Leitch, Victoria, Sparkes, Penny, Laurent, Laetitia, Adoum, Anne-Tounsia, Mannan, Naila, Komla-Ebri, Davide, Pollard, Andrea, Dewhurst, Hannah, Kaptoge, Stephen, Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia, Evangelou, Evangelos, Ohlsson, Claes

Relation: orcid:0000-0002-9105-2249

الاتاحة: https://espace.library.uq.edu.au/view/UQ:f64e5eb

المؤلفون: Morris, John A., Kemp, John P, Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan, Vulpescu, Nicholas A, Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu, Sergio, C Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee Lee, Vijay, Jinchu, Simon, Marie-Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne-Tounsia, Mannan, Naila S., Komla-Ebri, Davide, Pollard, Andrea S., Dewhurst, Hannah F., Hassell, Thomas, Beltajar, Michael-John G., Adams, Douglas J., Vaillancourt, Suzanne M., Kaptoge, Stephen K., Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia, Evangelou, Evangelos, Ohlsson, Claes, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas R., Tobias, Jonathan H., Gregson, Celia L., Harvey, Nicholas, Grundberg, Elin, Goltzman, David, Adams, David J, Lelliott, Christopher J., Hinds, David A., Ackert-Bicknell, Cheryl L., Hsu, Yi-Hsiang, Maurano, Matthew T., Croucher, Peter I., Williams, Graham R., Bassett, J.H. Duncan, Evans, David M., Richards, J. Brent

وصف الملف: text; slideshow; spreadsheet

Relation: https://eprints.soton.ac.uk/427202/1/Morrisetal2018.NatGen.Manuscript_clean.docx; https://eprints.soton.ac.uk/427202/2/Morrisetal2018.NatGen.Figure1.pptx; https://eprints.soton.ac.uk/427202/3/Morrisetal2018.NatGen.Figure2.pptx; https://eprints.soton.ac.uk/427202/4/Morrisetal2018.NatGen.Figure3.pptx; https://eprints.soton.ac.uk/427202/5/Morrisetal2018.NatGen.Figure4.pptx; https://eprints.soton.ac.uk/427202/6/Morrisetal2018.NatGen.Figure5.pptx; https://eprints.soton.ac.uk/427202/7/Copy_of_Morrisetal2018.NatGen.SupplementaryTables.xlsx; Morris, John A., Kemp, John P, Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan, Vulpescu, Nicholas A, Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu, Sergio, C Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee Lee, Vijay, Jinchu, Simon, Marie-Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne-Tounsia, Mannan, Naila S., Komla-Ebri, Davide, Pollard, Andrea S., Dewhurst, Hannah F., Hassell, Thomas, Beltajar, Michael-John G., Adams, Douglas J., Vaillancourt, Suzanne M., Kaptoge, Stephen K., Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia, Evangelou, Evangelos, Ohlsson, Claes, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas R., Tobias, Jonathan H., Gregson, Celia L., Harvey, Nicholas, Grundberg, Elin, Goltzman, David, Adams, David J, Lelliott, Christopher J., Hinds, David A., Ackert-Bicknell, Cheryl L., Hsu, Yi-Hsiang, Maurano, Matthew T., Croucher, Peter I., Williams, Graham R., Bassett, J.H. Duncan, Evans, David M. and Richards, J. Brent , 23andMe Research Team (2019) An atlas of genetic influences on osteoporosis in humans and mice. Nature Genetics, 51 (2), 258-266. (doi:10.1038/s41588-018-0302-x ).

الاتاحة: https://eprints.soton.ac.uk/427202/
https://eprints.soton.ac.uk/427202/1/Morrisetal2018.NatGen.Manuscript_clean.docx
https://eprints.soton.ac.uk/427202/2/Morrisetal2018.NatGen.Figure1.pptx
https://eprints.soton.ac.uk/427202/3/Morrisetal2018.NatGen.Figure2.pptx
https://eprints.soton.ac.uk/427202/4/Morrisetal2018.NatGen.Figure3.pptx
https://eprints.soton.ac.uk/427202/5/Morrisetal2018.NatGen.Figure4.pptx
https://eprints.soton.ac.uk/427202/6/Morrisetal2018.NatGen.Figure5.pptx
https://eprints.soton.ac.uk/427202/7/Copy_of_Morrisetal2018.NatGen.SupplementaryTables.xlsx

المؤلفون: Morris, John A., Kemp, John P., Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan C., Vulpescu, Nicholas A., Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu T., Sergio, C. Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee-Lee, Vijay, Jinchu, Simon, Marie-Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne-Tounsia, Mannan, Naila S., Komla-Ebri, Davide S. K., Pollard, Andrea S., Dewhurst, Hannah F., Hassall, Thomas A. D., 23andMe Research Team

مصطلحات موضوعية: Genetics, 1311 Genetics

Relation: orcid:0000-0002-9105-2249

الاتاحة: https://espace.library.uq.edu.au/view/UQ:c79e5e3

المؤلفون: Kemp, John P., Morris, John A., Medina-Gómez, Carolina, Forgetta, Vincenzo, Warrington, Nicole M., Youlten, Scott E., Zheng, Jie, Gregson, Celia L., Grundberg, Elin, Trajanoska, Katerina, Logan, John G., Pollard, Andrea S., Sparkes, Penny C., Ghirardello, Elena J., Allen, Rebecca, Leitch, Victoria D., Butterfield, Natalie C., Komla-Ebri, Davide, Adoum, Anne-Tounsia, Curry, Katharine F., White, Jacqueline K, Kussy, Fiona, Greenlaw, Keelin M., Xu, Changjang, Harvey, Nicholas C., Cooper, Cyrus, Adams, David J., Greenwood, Celia M.T., Maurano, Matthew T., Kaptoge, Stephen K., Rivadeneira, Fernando, Tobias, Jonathan H., Croucher, Peter I., Ackert-Bicknell, Cheryl L., Bassett, J.H. Duncan, Williams, Graham R., Richards, J. Brent, Evans, David M.

وصف الملف: text; image; spreadsheet

Relation: https://eprints.soton.ac.uk/413885/1/NG_A45024R_Manuscript.docx; https://eprints.soton.ac.uk/413885/2/NG_A45024R_Figure1.tiff; https://eprints.soton.ac.uk/413885/3/NG_A45024R_Figure2.tiff; https://eprints.soton.ac.uk/413885/4/NG_A45024R_Figure3.tif; https://eprints.soton.ac.uk/413885/5/NG_A45024R_Figure4.tif; https://eprints.soton.ac.uk/413885/6/NG_A45024R_Suppl_Figures_ISI_New.docx; https://eprints.soton.ac.uk/413885/7/NG_A45024R_Suppl_Tables.xlsx; https://eprints.soton.ac.uk/413885/8/Supplementary_Note.docx; Kemp, John P., Morris, John A., Medina-Gómez, Carolina, Forgetta, Vincenzo, Warrington, Nicole M., Youlten, Scott E., Zheng, Jie, Gregson, Celia L., Grundberg, Elin, Trajanoska, Katerina, Logan, John G., Pollard, Andrea S., Sparkes, Penny C., Ghirardello, Elena J., Allen, Rebecca, Leitch, Victoria D., Butterfield, Natalie C., Komla-Ebri, Davide, Adoum, Anne-Tounsia, Curry, Katharine F., White, Jacqueline K, Kussy, Fiona, Greenlaw, Keelin M., Xu, Changjang, Harvey, Nicholas C., Cooper, Cyrus, Adams, David J., Greenwood, Celia M.T., Maurano, Matthew T., Kaptoge, Stephen K., Rivadeneira, Fernando, Tobias, Jonathan H., Croucher, Peter I., Ackert-Bicknell, Cheryl L., Bassett, J.H. Duncan, Williams, Graham R., Richards, J. Brent and Evans, David M. (2017) Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis. Nature Genetics, 49 (10), 1468-1475. (doi:10.1038/ng.3949 ).

الاتاحة: https://eprints.soton.ac.uk/413885/
https://eprints.soton.ac.uk/413885/1/NG_A45024R_Manuscript.docx
https://eprints.soton.ac.uk/413885/2/NG_A45024R_Figure1.tiff
https://eprints.soton.ac.uk/413885/3/NG_A45024R_Figure2.tiff
https://eprints.soton.ac.uk/413885/4/NG_A45024R_Figure3.tif
https://eprints.soton.ac.uk/413885/5/NG_A45024R_Figure4.tif
https://eprints.soton.ac.uk/413885/6/NG_A45024R_Suppl_Figures_ISI_New.docx
https://eprints.soton.ac.uk/413885/7/NG_A45024R_Suppl_Tables.xlsx
https://eprints.soton.ac.uk/413885/8/Supplementary_Note.docx

المؤلفون: Butterfield, Natalie C, Curry, Katherine F, Steinberg, Julia, Dewhurst, Hannah, Komla-Ebri, Davide, Mannan, Naila S, Adoum, Anne-Tounsia, Leitch, Victoria D, Logan, John G, Waung, Julian A, Ghirardello, Elena, Southam, Lorraine, Youlten, Scott E, Wilkinson, J Mark, McAninch, Elizabeth A, Vancollie, Valerie E, Kussy, Fiona, White, Jacqueline K, Lelliott, Christopher J, Adams, David J, Jacques, Richard, Bianco, Antonio C, Boyde, Alan, Zeggini, Eleftheria, Croucher, Peter I, Williams, Graham R, Bassett, JH Duncan

مصطلحات موضوعية: Gene Editing, Mice, Knockout, Iodide Peroxidase, Bone and Bones, 3. Good health, Gonadotropin-Releasing Hormone, Disease Models, Animal, Mice, Cartilage, Phenotype, Drug Discovery, Osteoarthritis, Animals, Paired Box Transcription Factors, Clustered Regularly Interspaced Short Palindromic Repeats, Genetic Predisposition to Disease, CRISPR-Cas Systems, Genetic Association Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8635d16a3526e8a6bacf4646c85b738

المؤلفون: Paul Flicek, Raffaele Teperino, Lydia Teboul, Thomas Werner, Marie-France Champy, Christopher J. Lelliott, Graham R. Williams, Jacqueline K. White, Gregor Miller, Mary E. Dickinson, Ann M Flenniken, Radislav Sedlacek, Martin Hrabé de Angelis, John R. Seavitt, Peter I. Croucher, Maria del Mar Muniz Moreno, Sara Wells, Jan Rozman, Terrence F. Meehan, Kristian F Odfalk, Juan Gallegos, J. H. Duncan Bassett, Mohammed Selloum, John G. Logan, Sylvie Jacquot, Elena J. Ghirardello, Robert Braun, Frantisek Spoutil, Kevin C K Lloyd, Lore Becker, Stephen A. Murray, Jan Prochazka, Elif F. Acar, Taylor S Vales, Michelle Simon, Helmut Fuchs, Nadine Spielmann, Mark Griffiths, Piia Keskivali-Bond, Valerie Gailus-Durner, Tania Sorg, Christine Schütt, Jeremy Mason, Helen Parkinson, Karen L. Svenson, Abdel Ayadi, Anna L Swan, Jason D. Heaney, Colin McKerlie, Wolfgang Wurst, Ann-Marie Mallon, Heather Cater, Stefanie Leuchtenberger, Harald Grallert, Steve D.M. Brown, Stefan Brandmaier, Yann Herault, Philipp Mayer-Kuckuk, Corey L. Reynolds, Ala Moshiri, Robert Brommage, Derek D. Cissell, Lauryl M J Nutter, Connor Lally

المساهمون: MRC Harwell Institute [UK], German Research Center for Environmental Health - Helmholtz Center München (GmbH), German Center for Diabetes Research - Deutsches Zentrum für Diabetesforschung [Neuherberg] (DZD), Institute of Molecular Genetics of the Czech Academy of Sciences (IMG / CAS), Czech Academy of Sciences [Prague] (CAS), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Helmholtz-Zentrum München (HZM), The Wellcome Trust Sanger Institute [Cambridge], University of Michigan [Ann Arbor], University of Michigan System, University of California [Davis] (UC Davis), University of California, Baylor College of Medicine (BCM), Baylor University, European Molecular Biology Laboratory [Hinxton], University of Toronto, University of Manitoba [Winnipeg], Lunenfeld-Tanenbaum Research Institute [Toronto, Canada], French National Infrastructure for Mouse Phenogenomics (PHENOMIN), The Jackson Laboratory [Bar Harbor] (JAX), European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, Imperial College London, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Deutsches Zentrum für Neurodegenerative Erkrankungen [Ulm] (DZNE), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Munich Cluster for systems neurology [Munich] (SyNergy), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM)-Ludwig-Maximilians-Universität München (LMU), Garvan Institute of Medical Research [Sydney, Australia], St. Vincent’s Clinical School [Sydney, Australia], UNSW Faculty of Medicine [Sydney], University of New South Wales [Sydney] (UNSW)-University of New South Wales [Sydney] (UNSW), Université de Nouvelle-Galles du Sud - UNSW [Sydney, Australia], Mundlos, Stefan, Wellcome Trust, Commission of the European Communities, European Commission, Herault, Yann, Helmholtz Zentrum München = German Research Center for Environmental Health, University of California (UC), Garvan Institute of medical research, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Technische Universität München [München] (TUM), Technische Universität München [München] (TUM)-Ludwig-Maximilians-Universität München (LMU), Swan, Anna L [0000-0003-1810-3756], Rozman, Jan [0000-0002-8035-8904], Del Mar Muñiz Moreno, Maria [0000-0002-2662-890X], Leuchtenberger, Stefanie [0000-0003-2475-0810], Brommage, Robert [0000-0002-9947-3822], Grallert, Harald [0000-0002-6876-9655], Werner, Thomas [0000-0003-0402-4539], Teperino, Raffaele [0000-0001-8815-1409], Becker, Lore [0000-0002-6890-4984], Miller, Gregor [0000-0002-4281-4905], Seavitt, John R [0000-0003-3209-3187], Cissell, Derek D [0000-0002-6450-422X], Acar, Elif F [0000-0003-2908-7691], Lelliott, Christopher J [0000-0001-8087-4530], Braun, Robert E [0000-0003-3856-9465], Cater, Heather [0000-0002-8696-6070], Flicek, Paul [0000-0002-3897-7955], Ghirardello, Elena J [0000-0002-1100-9217], Heaney, Jason D [0000-0001-8475-8828], Lally, Connor [0000-0002-3801-1966], Logan, John G [0000-0003-2801-700X], Mason, Jeremy [0000-0002-2796-5123], Nutter, Lauryl MJ [0000-0001-9619-146X], Odfalk, Kristian F [0000-0003-4152-4583], Prochazka, Jan [0000-0003-4675-8995], Selloum, Mohammed [0000-0003-4057-3519], Spoutil, Frantisek [0000-0002-7310-3487], Svenson, Karen L [0000-0002-7928-1911], Vales, Taylor S [0000-0001-9751-5681], Wells, Sara E [0000-0002-0572-0600], White, Jacqueline K [0000-0001-6268-2826], Sedlacek, Radislav [0000-0002-3352-392X], Wurst, Wolfgang [0000-0003-4422-7410], Lloyd, KC Kent [0000-0002-5318-4144], Williams, Graham R [0000-0002-8555-8219], Herault, Yann [0000-0001-7049-6900], Brown, Steve DM [0000-0002-0617-4824], Hrabe de Angelis, Martin [0000-0002-7898-2353], Apollo - University of Cambridge Repository

المصدر: PLoS Genetics
PLoS Genetics, Public Library of Science, 2020, 16 (12), pp.e1009190. ⟨10.1371/journal.pgen.1009190⟩
PLoS genetics, vol 16, iss 12
PLoS Genet. 16:e1009190 (2021)
PLoS Genetics 16(12), e1009190 (2020). doi:10.1371/journal.pgen.1009190
PLOS Genetics
PLoS Genetics, 2020, 16 (12), pp.e1009190. ⟨10.1371/journal.pgen.1009190⟩
PLoS Genetics, Vol 16, Iss 12, p e1009190 (2020)

مصطلحات موضوعية: Male, Osteoporosis, genetics [Gene Expression Regulation], Transgenic, Transcriptome, Mice, 0302 clinical medicine, Animal Cells, Aetiology, Musculoskeletal System, Connective Tissue Cells, Genetics & Heredity, 0303 health sciences, Genomics, 3. Good health, Cellular Types, musculoskeletal diseases, Genotype, In silico, 1.1 Normal biological development and functioning, 03 medical and health sciences, genetics [Osteoporosis], Rheumatology, pathology [Osteoblasts], Genetic, Genome-Wide Association Studies, Genetics, GENOME-WIDE ASSOCIATION, Molecular Biology, Skeleton, Ecology, Evolution, Behavior and Systematics, METAANALYSIS, metabolism [Osteoblasts], 0604 Genetics, [SDV.GEN]Life Sciences [q-bio]/Genetics, Science & Technology, Osteoblasts, IDENTIFICATION, Biology and Life Sciences, Computational Biology, medicine.disease, COLLAGEN, Biological Tissue, OSTEOGENESIS IMPERFECTA, DISCOVERY, IMPC Consortium, Mutation, Animal Studies, Developmental Biology, Candidate gene, Cancer Research, Bone density, Gene Expression, Osteoclasts, [SDV.GEN] Life Sciences [q-bio]/Genetics, QH426-470, Bone remodeling, Bone Density, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Protein Interaction Maps, Connective Tissue Diseases, Promoter Regions, Genetic, Genetics (clinical), Bone mineral, Sex Characteristics, genetics [Bone Density], metabolism [Osteoclasts], Genetic Pleiotropy, Animal Models, pathology [Osteoclasts], Phenotype, DIFFERENTIATION, Experimental Organism Systems, ANIMAL-MODELS, Connective Tissue, SEX, Female, Anatomy, Technology Platforms, Life Sciences & Biomedicine, Research Article, metabolism [Osteoporosis], Mouse Models, 030209 endocrinology & metabolism, Mice, Transgenic, Biology, Research and Analysis Methods, Promoter Regions, Model Organisms, Underpinning research, medicine, Animals, ddc:610, Bone, 030304 developmental biology, Human Genetics, Cell Biology, Genome Analysis, Gene Ontology, Gene Expression Regulation, Musculoskeletal, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd75524d05346ddd91358167446ef7f4