المؤلفون: Alaa Amash, Gesa Volkers, Patrick Farber, Daniel Griffin, K. Shawn Davison, Allison Goodman, Raffi Tonikian, Aaron Yamniuk, Bryan Barnhart, Tim Jacobs

المصدر: mAbs, Vol 16, Iss 1 (2024)

مصطلحات موضوعية: Antibody, bispecific, developability, format, immunogenicity, manufacturability, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/020fa653c746460f9979c68b5e356aea

المؤلفون: Nina E. Weisser, Mario Sanches, Eric Escobar-Cabrera, Jason O’Toole, Elizabeth Whalen, Peter W. Y. Chan, Grant Wickman, Libin Abraham, Kate Choi, Bryant Harbourne, Antonios Samiotakis, Andrea Hernández Rojas, Gesa Volkers, Jodi Wong, Claire E. Atkinson, Jason Baardsnes, Liam J. Worrall, Duncan Browman, Emma E. Smith, Priya Baichoo, Chi Wing Cheng, Joy Guedia, Sohyeong Kang, Abhishek Mukhopadhyay, Lisa Newhook, Anders Ohrn, Prajwal Raghunatha, Matteo Zago-Schmitt, Joseph D. Schrag, Joel Smith, Patricia Zwierzchowski, Joshua M. Scurll, Vincent Fung, Sonia Black, Natalie C. J. Strynadka, Michael R. Gold, Leonard G. Presta, Gordon Ng, Surjit Dixit

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8a871ad93e594eeba832492229b1329b

المؤلفون: Kate Gibson, Lauren Chong, Tim Jacobs, Patrick Farber, Antonios Samiotakis, Harveer Dhupar, Allison Goodman, Cindy-Lee Crichlow, Melissa Cid, Ping Xiang, Ahn Lee, Irene Yu, Gabrielle Conaghan, Nathalie Blamey, Vivian Li, Valentine de Puyraimond, Patrick Rowe, Stephanie K Masterman, Raffi Tonikian, Bryan C Barnhart, Juntao (Matt) Mai, Philippe Pouliot, Kate Caldwell, Lauren Clifford, Janice Reimer, Karine Herve, John Marwick, Lena M Bolten, Tova Pinsky, Gesa Volkers, Girija Bodhankar, Caitlyn De Jong, Sophie Cullen, Stefan Hannie, Rhys Chappell, Emma Lathouwers, Kirstin Brown, Mark Fogg, Aaron Yamniuk

المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/d71de961c12640bd9fb3d2088e75ea52

المؤلفون: Christian Lizak, Liam J. Worrall, Lars Baumann, Moritz M. Pfleiderer, Gesa Volkers, Tianjun Sun, Lyann Sim, Warren Wakarchuk, Stephen G. Withers, Natalie C. J. Strynadka

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/fabd1f28b66b4a33a5fbc85e3dd477c6

المؤلفون: Natalie C. J. Strynadka, Gesa Volkers, Seino A. K. Jongkees, Liam J. Worrall, Angel C. Y. Yu, Stephen G. Withers

المصدر: Glycobiology

مصطلحات موضوعية: medicine.medical_treatment, Cell, Virulence, Neuraminidase, Sialidase, Biochemistry, Genome, Microbiology, 03 medical and health sciences, Propionibacterium acnes, Structural Biology, Acne Vulgaris, medicine, Endocarditis, Humans, Cytotoxicity, 030304 developmental biology, Skin, 0303 health sciences, biology, 030302 biochemistry & molecular biology, biology.organism_classification, medicine.disease, 3. Good health, medicine.anatomical_structure, Cytokine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6b68913bbc1fd6a7d02c926cf8c3f8
https://pubmed.ncbi.nlm.nih.gov/34792586

المؤلفون: Johannes J. Preidl, Jürgen Niesser, Christian Lizak, Gesa Volkers, Vinayaga S. Gnanapragassam, Frederico I Rosell, Ruediger Horstkorte, Natalie C. J. Strynadka, Jörg Rademann

المصدر: ACS Chemical Biology. 13:2320-2328

مصطلحات موضوعية: 0301 basic medicine, Glycoconjugate, Cell, Biochemistry, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Cytidine Monophosphate, medicine, Humans, Enzyme Inhibitors, Neural Cell Adhesion Molecules, Fluorescent Dyes, chemistry.chemical_classification, Drug discovery, Polysialic acid, General Medicine, Sialyltransferases, 3. Good health, Molecular Docking Simulation, 030104 developmental biology, medicine.anatomical_structure, chemistry, Cell culture, 030220 oncology & carcinogenesis, Cancer cell, Sialic Acids, Molecular Medicine, Neural cell adhesion molecule, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3401e6c0b6ddd9f5cce06329cfefef72
https://doi.org/10.1021/acschembio.8b00478

المؤلفون: Jeff Proctor, Gerry Rowse, D.M. Mills, Liz Stangle, Iulia Dude, Ryan Blackler, Akram Khodabandehloo, Joel B. Smith, David Douda, Grant Raymond Wickman, Thomas Spreter, Patricia Zwierzchowski, Surjit Bhimarao Dixit, Desmond Lau, Stuart D. Barnscher, Genevieve Desjardins, Laurence Madera, Nicole Afacan, Gesa Volkers, Leisa Stenberg, Jennifer Leah Bishop, Sifa Arrafi, Maya Poffenberger, Irene Yu

المصدر: Cancer Research. 81:1788-1788

مصطلحات موضوعية: Cancer Research, Therapeutic index, Protease, Oncology, business.industry, medicine.medical_treatment, Cancer research, Tumor specific, Interleukin 12, Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f60b9702ff910c14160182f6e96e5105
https://doi.org/10.1158/1538-7445.am2021-1788

المؤلفون: Charles Stevens, Lisa Newhook, Thomas Spreter, Harsh Pratap, Freiburger Lee, Daniel T. Patton, Duncan Browman, D.M. Mills, Renee Duan, Gesa Volkers, Anna von Rossum, Brandon Clavette, Elizabeth C. Halvorsen, Dimitri Tcaciuc

المصدر: Cancer Research. 81:1737-1737

مصطلحات موضوعية: Cancer Research, Bispecific antibody, Oncology, Chemistry, Valency, Biophysics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fcd71700d990ec79de52eb0e7794d0dd
https://doi.org/10.1158/1538-7445.am2021-1737

المؤلفون: Gesa Volkers, Javairia Rahim, Florian Heinkel, Anna von Rossum, Leisa Stenberg, Purva Bhojane, Surjit Bhimarao Dixit, Eric Escobar-Cabrera, Thomas Spreter, Sifa Arrafi, Liz Stangle, Harsh Pratap

المصدر: Cancer Research. 81:924-924

مصطلحات موضوعية: Therapeutic window, Cancer Research, Oncology, biology, business.industry, Cancer research, biology.protein, Tumor specific, Medicine, Immune modulation, Antibody, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3cb3833799c140fd6d65215bf44db479
https://doi.org/10.1158/1538-7445.am2021-924

المؤلفون: David H. Kwan, Emilie Lameignere, Nichollas E. Scott, Liam J. Worrall, Lars Baumann, Gesa Volkers, Leonard J. Foster, Natalie C. J. Strynadka, Ching-Ching Yu, Warren W. Wakarchuk, Gregory A. Wasney, Stephen G. Withers

المصدر: Nature Structural & Molecular Biology. 22:627-635

مصطلحات موضوعية: Models, Molecular, Glycan, Glycosylation, Stereochemistry, Sialyltransferase, Molecular Sequence Data, Crystallography, X-Ray, Mass Spectrometry, chemistry.chemical_compound, Protein structure, N-linked glycosylation, Polysaccharides, Structural Biology, Animals, Humans, Amino Acid Sequence, Structural motif, Neural Cell Adhesion Molecules, Molecular Biology, Ternary complex, Cells, Cultured, chemistry.chemical_classification, Binding Sites, Sequence Homology, Amino Acid, biology, Recombinant Proteins, Sialyltransferases, Protein Structure, Tertiary, Amino acid, Sialic acid, carbohydrates (lipids), Kinetics, chemistry, Biochemistry, Mutation, Sialic Acids, biology.protein, Electrophoresis, Polyacrylamide Gel, Chromatography, Thin Layer, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872eefa27ca0d438d54f3a35a5e74954
https://doi.org/10.1038/nsmb.3060

المؤلفون: Gesa Volkers, Lothar Petruschka, Winfried Hinrichs

المصدر: Journal of Medicinal Chemistry. 54:5108-5115

مصطلحات موضوعية: Models, Molecular, Protein Conformation, medicine.drug_class, Tetracycline, Tetracycline antibiotics, Antibiotics, Repressor, Crystallography, X-Ray, Protein–protein interaction, chemistry.chemical_compound, Allosteric Regulation, Transcription (biology), Drug Discovery, medicine, Chelation, TetR, Tetracycline Resistance, Surface Plasmon Resonance, Recombinant Proteins, Anti-Bacterial Agents, Repressor Proteins, chemistry, Biochemistry, Tetracyclines, Molecular Medicine, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd9469a91afbd2b789c64b9ae073525
https://doi.org/10.1021/jm200332e

المؤلفون: Winfried Hinrichs, Gesa Volkers, Gottfried J. Palm, Linda Schuldt, Gerard D. Wright

المصدر: Acta Crystallographica Section F Structural Biology and Crystallization Communications. 66:611-614

مصطلحات موضوعية: Tetracycline, Biophysics, Triclinic crystal system, Crystallography, X-Ray, Biochemistry, Mixed Function Oxygenases, law.invention, Hydroxylation, chemistry.chemical_compound, Structural Biology, law, Genetics, medicine, Bacteroides, Crystallization, biology, Monooxygenase, Condensed Matter Physics, biology.organism_classification, Crystallography, chemistry, Crystallization Communications, Bacteroides thetaiotaomicron, Monoclinic crystal system, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9ea7cb61c7f5ad3fb51f05289b520b
https://doi.org/10.1107/s174430911001225x

المؤلفون: Santosh Panjikar, Gesa Volkers, João M. Damas, Cláudio M. Soares, Gottfried J. Palm, Winfried Hinrichs

المصدر: Acta crystallographica. Section D, Biological crystallography. 69(Pt 9)

مصطلحات موضوعية: Stereochemistry, Tetracycline, medicine.drug_class, Tetracycline antibiotics, Flavoprotein, Minocycline, Crystallography, X-Ray, Tigecycline, Mixed Function Oxygenases, Hydroxylation, chemistry.chemical_compound, Bacterial Proteins, Structural Biology, medicine, Bacteroides, Binding site, Binding Sites, biology, Chemistry, Tetracycline Resistance, Active site, General Medicine, Monooxygenase, Anti-Bacterial Agents, Oxygen, Biochemistry, biology.protein, EF-Tu, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be435e28474334224f61bf87c2db760
https://pubmed.ncbi.nlm.nih.gov/23999299

المؤلفون: Winfried Hinrichs, Gesa Volkers, Gerard D. Wright, Gottfried J. Palm, Manfred S. Weiss

المصدر: FEBS letters. 585(7)

مصطلحات موضوعية: Models, Molecular, Antibiotic resistance, Tetracycline, medicine.drug_class, Tetracycline antibiotics, TetX, Biophysics, Tigecycline, Crystallography, X-Ray, Biochemistry, Mixed Function Oxygenases, Structural Biology, Genetics, medicine, Bacteroides, Molecular Biology, Binding Sites, Flavin, biology, Rational design, Tetracycline Resistance, Cell Biology, biology.organism_classification, Tetracycline degradation, Protein Structure, Tertiary, Oxygen, Flavin-Adenine Dinucleotide, Efflux, Bacteroides thetaiotaomicron, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197ef6c68d7720d2c32c23cfc0c9b812
https://pubmed.ncbi.nlm.nih.gov/21402075

المؤلفون: Gesa Volkers, Natalie C. J. Strynadka, Emilie Lameignere, Liam J. Worrall

المصدر: Acta Crystallographica Section A Foundations and Advances. 70:C482-C482

مصطلحات موضوعية: Inorganic Chemistry, Structural Biology, Computer science, General Materials Science, Computational biology, Physical and Theoretical Chemistry, Condensed Matter Physics, Biochemistry, Structure and function

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::89724d2c81a8a843a9f3b7277f94b539
https://doi.org/10.1107/s2053273314095175

المؤلفون: Winfried Hinrichs, Manfred S. Weiss, Gesa Volkers, Gottfried J. Palm, Gerard D. Wright

المصدر: Acta Crystallographica Section A Foundations of Crystallography. 66:s144-s145

مصطلحات موضوعية: Biochemistry, Structural Biology, Chemistry, Tetracycline, medicine, Monooxygenase, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e788de34b1e3847894d37eff24d3f2af
https://doi.org/10.1107/s0108767310096790