المؤلفون: Pranay Shah, Ross Hill, Camille Dion, Stephen J. Clark, Abdulkadir Abakir, Jeroen Willems, Mark J. Arends, Juan I. Garaycoechea, Harry G. Leitch, Wolf Reik, Gerry P. Crossan

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/9298bed0fab347d4ab08101e4f2d4f6c

المؤلفون: Ross J. Hill, Nazareno Bona, Job Smink, Hannah K. Webb, Alastair Crisp, Juan I. Garaycoechea, Gerry P. Crossan

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/f0329d797201440c9a105480326a2843

المؤلفون: Carla Umansky, Agustín E. Morellato, Matthias Rieckher, Marco A. Scheidegger, Manuela R. Martinefski, Gabriela A. Fernández, Oleg Pak, Ksenia Kolesnikova, Hernán Reingruber, Mariela Bollini, Gerry P. Crossan, Natascha Sommer, María Eugenia Monge, Björn Schumacher, Lucas B. Pontel

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/653aae910d4d4b0192f151bf36477da9

المؤلفون: Jonathan Ribeiro, Gerry P. Crossan

المصدر: Nucleic Acids Research.

مصطلحات موضوعية: endocrine system, Genetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159fafdca971cedbb241790fda6056fc
https://doi.org/10.1093/nar/gkad168

المؤلفون: Gerry P. Crossan, Ross J. Hill

المصدر: Nature genetics

مصطلحات موضوعية: Genome instability, Male, DNA Repair, DNA repair, DNA damage, Cellular differentiation, Apoptosis, Biology, Germline, Article, Genomic Instability, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Genetics, medicine, Animals, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Aldehydes, Genome, Mutagenesis, Cell Differentiation, DNA, Endonucleases, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Meiosis, medicine.anatomical_structure, Cross-Linking Reagents, Fertility, Germ Cells, chemistry, Female, 030217 neurology & neurosurgery, Germ cell, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964a2711d9f018a5d82a6f663f807144
http://europepmc.org/articles/PMC6675612

المؤلفون: Lee Mulderrig, Naomi Park, Serena Nik-Zainal, Frederic Langevin, Juan I. Garaycoechea, Guillaume Guilbaud, Fentang Yang, Gerry P. Crossan, Ketan J. Patel, Sophie Roerink, Sandra Louzada, Michael R. Stratton

المصدر: Nature. 553:171-177

مصطلحات موضوعية: Male, 0301 basic medicine, Genome instability, DNA End-Joining Repair, Cell Survival, DNA damage, Acetaldehyde, Biology, medicine.disease_cause, Genomic Instability, Article, Mice, 03 medical and health sciences, medicine, Animals, DNA Breaks, Double-Stranded, Ku Autoantigen, Mutation, Multidisciplinary, Ethanol, Whole Genome Sequencing, Fanconi Anemia Complementation Group D2 Protein, Alcohol Dehydrogenase, Hematopoietic Stem Cell Transplantation, Recombinational DNA Repair, Genes, p53, Hematopoietic Stem Cells, Cell biology, Mice, Inbred C57BL, Transplantation, Haematopoiesis, Fanconi Anemia, 030104 developmental biology, Female, Tumor Suppressor Protein p53, Stem cell, Homologous recombination, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8c4f41485eb2814ca4ed75f1c67c97
https://doi.org/10.1038/nature25154

المؤلفون: Rui Yu, Verena Broecker, Guillermo Burgos-Barragan, James A. Swenberg, Mark J. Arends, Gayathri Chandrasekaran, Ketan J. Patel, Gerry P. Crossan, Lucas B. Pontel, Wei Wei, Limin Liu, Iván V. Rosado, Juan I. Garaycoechea

المساهمون: Universidad de Sevilla. Departamento de Genética, Medical Research Council. UK, Instituto de Salud Carlos III. España, Ministerio de Economía y Competitividad (MINECO). España, National Institute of Environmental Health Sciences (NIEHS). U.S., Texas Commission for Environmental Quality. U.S., Wellcome Trust. UK

المصدر: idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Molecular Cell
Pontel, L B, Rosado, I V, Burgos-Barragan, G, Garaycoechea, J I, Yu, R, Arends, M J, Chandrasekaran, G, Broecker, V, Wei, W, Liu, L, Swenberg, J A, Crossan, G P & Patel, K J 2015, ' Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen ', Molecular Cell, vol. 60, no. 1, pp. 177-188 . https://doi.org/10.1016/j.molcel.2015.08.020

مصطلحات موضوعية: DNA damage, Endogeny, Kidney, Article, DNA Adducts, Gene Knockout Techniques, Mice, Formaldehyde, medicine, Animals, Molecular Biology, Carcinogen, Cells, Cultured, Alcohol dehydrogenase, biology, Fanconi Anemia Complementation Group D2 Protein, Alcohol Dehydrogenase, Kidney metabolism, Hematopoietic stem cell, Cell Biology, Hematopoietic Stem Cells, Molecular biology, 3. Good health, Cell biology, Haematopoiesis, medicine.anatomical_structure, Liver, biology.protein, Carcinogens, Stem cell, Mutagens

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8f1fa5e33bd087a5587511933f8814

المؤلفون: Gerry P. Crossan

المصدر: Blood. 128:2748-2750

مصطلحات موضوعية: 0301 basic medicine, Immunology, nutritional and metabolic diseases, Hematopoietic stem cell, Cell Biology, Hematology, Type 2 diabetes, Biology, medicine.disease, Biochemistry, Metformin, 03 medical and health sciences, 030104 developmental biology, medicine.anatomical_structure, Fanconi anemia, hemic and lymphatic diseases, medicine, Cancer research, Cancer risk, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::66f6e25059d37dd72e5ca17e775aab51
https://doi.org/10.1182/blood-2016-11-748129

المؤلفون: Juan I. Garaycoechea, Jan Silhan, Orlando D. Schärer, Shivam Mukherjee, Michael R. G. Hodskinson, Gerry P. Crossan, Ketan J. Patel, Christopher M. Johnson

المصدر: Molecular Cell

مصطلحات موضوعية: Genome instability, DNA Repair, DNA damage, DNA repair, Bone Marrow Cells, Mice, Transgenic, macromolecular substances, Biology, Article, Recombinases, DNA Adducts, Mice, chemistry.chemical_compound, Neoplasms, DNA Crosslinking, Animals, Replication protein A, Molecular Biology, Nuclease, Base Sequence, Tumor Suppressor Proteins, technology, industry, and agriculture, Cell Biology, Endonucleases, Hematopoietic Stem Cells, Molecular biology, DNA-Binding Proteins, Mice, Inbred C57BL, chemistry, biology.protein, Nucleic Acid Conformation, DNA, DNA Damage, Nucleotide excision repair

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d241584e6440b138596dda1fde877445

المؤلفون: Juan I. Garaycoechea, Gerry P. Crossan, Mark J. Arends, Frederic Langevin, Ketan J. Patel, Maria Daly

المصدر: Nature. 489:571-575

مصطلحات موضوعية: Male, Aging, DNA Repair, DNA repair, DNA damage, Aldehyde dehydrogenase, Acetaldehyde, Kaplan-Meier Estimate, Mice, Bone Marrow, hemic and lymphatic diseases, FANCD2, medicine, Animals, Progenitor cell, Mice, Knockout, Aldehydes, Leukemia, Multidisciplinary, Ethanol, biology, Aldehyde Dehydrogenase, Mitochondrial, Fanconi Anemia Complementation Group D2 Protein, Bone marrow failure, Aldehyde Dehydrogenase, Hematopoietic Stem Cells, medicine.disease, Mice, Inbred C57BL, Haematopoiesis, Fanconi Anemia, Immunology, biology.protein, Cancer research, Female, Stem cell, DNA Damage, Mutagens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a0d93666d83ccd453f1f0124b020c9
https://doi.org/10.1038/nature11368

المؤلفون: Gerry P. Crossan, Ketan J. Patel

المصدر: The Journal of Pathology. 226:326-337

مصطلحات موضوعية: Complementation, Genetics, Genome instability, chemistry.chemical_compound, chemistry, DNA repair, DNA replication, DNA Repair Pathway, Biology, Gene, Phenotype, DNA, Pathology and Forensic Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a5727101f61e95b1048a294a35ddcc45
https://doi.org/10.1002/path.3002

المؤلفون: Mark J. Arends, Iván V. Rosado, Frederic Langevin, Ketan J. Patel, Gerry P. Crossan

المصدر: Nature. 475:53-58

مصطلحات موضوعية: Cisplatin, congenital, hereditary, and neonatal diseases and abnormalities, Multidisciplinary, DNA damage, nutritional and metabolic diseases, DNA Repair Pathway, Biology, medicine.disease, medicine.disease_cause, Fanconi anemia, hemic and lymphatic diseases, FANCD2, Immunology, medicine, Cancer research, Carcinogen, Genotoxicity, medicine.drug, ALDH2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::302e8a07b6d4a5773946145b2b2b009c
https://doi.org/10.1038/nature10192

المؤلفون: Gerry P. Crossan, Mikko I. Kettunen, Frederic Langevin, Mark J. Arends, David Y. Lewis, Sanger Mouse Genetics, Iván V. Rosado, David J. Adams, Louise van der Weyden, Pierre-Henri L. Gaillard, Ferdia A. Gallagher, Ketan J. Patel, Kevin M. Brindle, Rebecca E. McIntyre

المساهمون: Medical Research Council, The Wellcome Trust Sanger Institute [Cambridge], Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), Centre de Recherche en Cancérologie de Marseille (CRCM / U891 Inserm), Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Cancer Research UK Cambridge Institute [Cambridge, Royaume-Uni] (CRUK), University of Cambridge [UK] (CAM), Addenbrooke's Hospital, Cambridge University NHS Trust

المصدر: Nature Genetics
Nature Genetics, Nature Publishing Group, 2011, 43 (2), pp.147-152. ⟨10.1038/ng.752⟩
Crossan, G P, van der Weyden, L, Rosado, I V, Langevin, F, Gaillard, P-H L, McIntyre, R E, Gallagher, F, Kettunen, M I, Lewis, D Y, Brindle, K, Arends, M J & Adams, D J & Patel, K J 2011, ' Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia ', Nature Genetics, vol. 43, no. 2, pp. 147-152 . https://doi.org/10.1038/ng.752
Nature genetics

مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, Fanconi anemia, complementation group C, DNA damage, Regulator, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], Biology, Article, Recombinases, Mice, 03 medical and health sciences, 0302 clinical medicine, Fanconi anemia, hemic and lymphatic diseases, Genetics, medicine, Recombinase, Animals, Humans, Gene, Cellular Senescence, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Mice, Knockout, Phenocopy, 0303 health sciences, Genetic Complementation Test, nutritional and metabolic diseases, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.BBM.MN]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular Networks [q-bio.MN], Fibroblasts, Hematopoietic Stem Cells, medicine.disease, Magnetic Resonance Imaging, Cross-Linking Reagents, Fanconi Anemia, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, 030220 oncology & carcinogenesis, Female, Cell aging, DNA Damage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81175b7943a670092081f0bdd7fd2d8b
https://doi.org/10.1038/ng.752

المؤلفون: Michael R. G. Hodskinson, Gerry P. Crossan, Ketan J. Patel

المصدر: Cancer Cell. 20:693-695

مصطلحات موضوعية: endocrine system, Cancer Research, endocrine system diseases, Tumor suppressor gene, Cell Biology, Biology, Ring (chemistry), medicine.disease, medicine.disease_cause, Oncology, Complex protein, Cancer cell, Immunology, medicine, Cancer research, Tumor suppressor activity, skin and connective tissue diseases, Ovarian cancer, Carcinogenesis, Human breast

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be091902ae43f32064856aebd333b69b
https://doi.org/10.1016/j.ccr.2011.11.019

المؤلفون: Niels de Wind, Gerry P. Crossan, Gareth King, Frederic Langevin, Nina Oberbeck, Ketan J. Patel

المصدر: Molecular Cell, 55(6), 807-817

مصطلحات موضوعية: DNA damage, Acetaldehyde, Biology, Aldehyde Dehydrogenase 1 Family, Mice, Fanconi anemia, Pregnancy, hemic and lymphatic diseases, medicine, Animals, Humans, Molecular Biology, ALDH2, Fetus, Genome, Ethanol, Fanconi Anemia Complementation Group A Protein, Aldehyde Dehydrogenase, Mitochondrial, Retinal Dehydrogenase, Embryo, Cell Biology, DNA Repair Pathway, Aldehyde Dehydrogenase, medicine.disease, Embryo, Mammalian, Hematopoietic Stem Cells, Molecular biology, Embryonic stem cell, FANCA, Cell biology, Isoenzymes, Mice, Inbred C57BL, Disease Models, Animal, Fanconi Anemia, Animals, Newborn, embryonic structures, Female, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29542053506f431b1430ad1cd5c6458
https://pubmed.ncbi.nlm.nih.gov/25238193

المؤلفون: Frédéric P M, Langevin, Juan I, Garaycoechea, Gerry P, Crossan, Ketan J, Patel

المصدر: Medecine sciences : M/S. 29(4)

مصطلحات موضوعية: Mice, Knockout, Aldehydes, Mice, Fanconi Anemia, Aldehyde Dehydrogenase, Mitochondrial, Animals, Humans, DNA, Aldehyde Dehydrogenase, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::874f14e3374f7c0a5e1b6c509184f61f
https://pubmed.ncbi.nlm.nih.gov/23621931

المؤلفون: Janine L. Bakker, Kathleen Claes, Muriel A. Adank, Marc Tischkowitz, Bruce Poppe, Nelly Sabbaghian, Johan P. de Winter, Quinten Waisfisz, Kim De Leeneer, Hans J. J. P. Gille, Henk M.W. Verheul, Gerry P. Crossan, Hanne Meijers-Heijboer, Saskia E. van Mil

المساهمون: Cancer Center Amsterdam, Amsterdam Reproduction & Development (AR&D), Human Genetics, Human genetics, Medical oncology, CCA - Oncogenesis

المصدر: Bakker, J L, van Mil, S E, Crossan, G, Sabbaghian, N, De Leeneer, K, Poppe, B, Adank, M A, Gille, J J P, Verheul, H, Meijers-Heijboer, H, de Winter, J P, Claes, K, Tischkowitz, M & Waisfisz, Q 2013, ' Analysis of the Novel Fanconi Anemia Gene SLX4/FANCP in Familial Breast Cancer Cases ', Human Mutation, vol. 34, no. 1, pp. 70-73 . https://doi.org/10.1002/humu.22206
Human mutation, 34(1), 70-73. Wiley-Liss Inc.
Human Mutation, 34(1), 70-73. Wiley-Liss Inc.

مصطلحات موضوعية: Adult, Male, PALB2, DNA Mutational Analysis, Mutation, Missense, Breast Neoplasms, Biology, Frameshift mutation, Breast Neoplasms, Male, Cohort Studies, Recombinases, Breast cancer, Germline mutation, Fanconi anemia, Genetics, medicine, Missense mutation, Humans, Genetic Predisposition to Disease, skin and connective tissue diseases, Genetics (clinical), Aged, Aged, 80 and over, Family Health, Splice site mutation, BRIP1, Middle Aged, medicine.disease, Fanconi Anemia, Mutation, Female, RNA Splice Sites

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a745a8c1c8289efabb32ec816430e1
https://pubmed.ncbi.nlm.nih.gov/22911665

المؤلفون: Iván V. Rosado, Gerry P. Crossan, Ketan J. Patel, Minoru Takata, Frederic Langevin

المصدر: Nature structuralmolecular biology. 18(12)

مصطلحات موضوعية: Fanconi anemia, complementation group C, DNA Repair, DNA damage, Formaldehyde, Fanconi Anemia Complementation Group L Protein, Biology, Cell Line, chemistry.chemical_compound, Gene Knockout Techniques, Structural Biology, Fanconi anemia, medicine, Animals, Molecular Biology, chemistry.chemical_classification, Fanconi Anemia Complementation Group C Protein, DNA Repair Pathway, Metabolism, medicine.disease, Aldehyde Oxidoreductases, Enzyme, Fanconi Anemia, chemistry, Biochemistry, Chickens, DNA, Metabolic Networks and Pathways

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c93d4ad6afe5fcd6a0e0a0fdbdbda60
https://pubmed.ncbi.nlm.nih.gov/22531379

المؤلفون: John R. Ferdinand, Ketan J. Patel, Felix A. Dingler, Stephen O'Rahilly, Christopher L. Millington, Liam Gaul, Menna R. Clatworthy, Lee Mulderrig, Gerry P. Crossan, Zewen K. Tuong, John Tadross, Mark J. Arends, Juan I. Garaycoechea

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Nature, 600(7887), 158-163. Nature Publishing Group
Nature

مصطلحات موضوعية: Male, Cachexia, Growth Differentiation Factor 15, Transcription, Genetic, DNA damage, Endogeny, RNA polymerase II, Cockayne syndrome, Kidney Tubules, Proximal, Mice, Stress, Physiological, Transcription (biology), Formaldehyde, medicine, Animals, Renal Insufficiency, Cockayne Syndrome, Poly-ADP-Ribose Binding Proteins, Multidisciplinary, biology, Chemistry, Neurodegeneration, Alcohol Dehydrogenase, Brain, medicine.disease, Cell biology, Disease Models, Animal, DNA Repair Enzymes, biology.protein, Female, ERCC6, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c126b81815336d8114d275f2fc5d2869

المؤلفون: Juan I. Garaycoechea, Ketan J. Patel, Gerry P. Crossan

المصدر: Cell Stem Cell. (2):111-112

مصطلحات موضوعية: Evolutionary biology, Incidence (epidemiology), Genetics, Molecular Medicine, Cell Biology, Biology, Stem cell, Bioinformatics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649f4740fd19a7ff33fbd77b8c38cbac